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Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 15 January 2026 | Viewed by 46

Special Issue Editors


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Guest Editor
Dipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy
Interests: helicobacter pylori infection; epidemiology; diagnosis and treatment; glucose 6 phosphate dehy-drogenase; celiac disease; GERD; IBD; nutrition; longevity; probiotic.
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Dipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Viale San Pietro 8, 07100 Sassari, Italy
Interests: gastrointestinal endoscopy; inflammatory bowel diseases; digestive oncology; neuroendocrine neoplasms; evidence-based medicine; systematic reviews; meta-analysis

Special Issue Information

Dear Colleagues,

Artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL) techniques, is demonstrating remarkable potential in advancing the field of gastroenterology. One of the most promising areas of application is medical imaging, where AI is being integrated into a wide range of modalities, ranging from abdominal ultrasonography to conventional endoscopy. In the context of cancer screening, AI-powered systems are proving especially effective in the early detection of precancerous and cancerous lesions, improving diagnostic accuracy and reducing the likelihood of missed findings. Notably, AI-enhanced endoscopic ultrasonography has shown promising performance in distinguishing between benign and malignant lesions, thereby supporting more accurate differential diagnoses. Additionally, AI is increasingly being utilized in prognostic modeling, offering innovative tools for predicting patient outcomes and informing clinical decision-making. Beyond clinical prediction, AI also serves as a valuable resource for enhancing both patient and physician understanding of various gastrointestinal diseases, supporting more informed discussions, shared decision-making, and overall health literacy. Although the promise of AI in healthcare is well recognized, its integration into clinical practice introduces varied challenging ethical considerations, including the protection of patient privacy, the potential for algorithmic bias, the transparency and interpretability of AI systems, the need for robust validation protocols, and the evolving responsibilities of medical professionals in an AI-assisted landscape.

This Special Issue will explore the growing impact of AI in the field of gastroenterology, offering a comprehensive overview of current evidence. In addition to summarizing the existing data, this Special Issue also presents emerging trends and future perspectives, focusing on the potential of AI to further revolutionize patient management and support personalized medicine in gastroenterology.

Prof. Dr. Maria Pina Dore
Prof. Dr. Elettra Merola
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • gastroenterology
  • medical imaging
  • endoscopy
  • prognostic modeling
  • ethical considerations

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Published Papers

This special issue is now open for submission.
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