Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Mental Health".

Deadline for manuscript submissions: 30 July 2025 | Viewed by 1835

Special Issue Editors


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Guest Editor
Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples “Federico II”, 80131 Naples, Italy
Interests: clinical health psychology; psychological adjustment; illness experience; relational resources; psychological intervention

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Guest Editor
Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples “Federico II”; Program of Clinical Psychopathology, AOU Federico II University Hospital, 80131 Naples, Italy
Interests: psychopathology; personality disorders; neural correlates of consciousness; medical decision-making

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Guest Editor
Department of Neurosciences, University of Turin; Clinical Psychology Unit, AOU Città della Salute e della Scienza Hospital, 10126 Turin, Italy
Interests: palliative care; dignity care; psychotherapy; spirituality; existential distress; end of care; cancer

Special Issue Information

Dear Colleagues,

Research on the experience of oncological diagnoses and treatments has consistently demonstrated a significant impact on psychological, social, behavioral, and emotional domains. Psycho-oncology plays a crucial role in addressing the burden faced by patients, families, and caregivers throughout the cancer journey, influencing health outcomes as well. From this perspective, emerging evidence shows that psychological distress not only affects mental health but also directly impacts treatment outcomes. For instance, recent studies on cancer immunotherapy have demonstrated that individuals experiencing emotional distress before treatment tend to have worse outcomes. Preventing psychological distress and addressing the mental health of cancer patients and their communities should be a priority, especially in response to the predicted exponential growth in cancer incidence by 2030, as forecasted by international scientific organizations. The primary focus should be on developing a unified and synergistic healthcare response that respects the complexity of the cancer experience, adapting efficient interventions to recover the life dimensions damaged by the illness, as well as facing the palliative stage and end of life. To fully develop the role of psycho-oncology in promoting well-being and enhancing treatment efficacy, a multidimensional approach is essential.

This Special Issue invites scholars to contribute to the debate on these domains by submitting research papers, longitudinal studies, and reviews, conducted through qualitative, quantitative, or mixed methods.

Topics should relate, but are not limited, to the following thematic areas:

  1. Psychological, psychopharmacological, and social interventions in cancer care;
  2. Palliative care, end-of-life, and ethical issues;
  3. Caregiver support and family-centered approaches;
  4. Challenges in cancer survivorship: oncofertility, resilience, social reintegration, fear of recurrence, and aging;
  5. Pediatric psycho-oncology;
  6. Psychoneuroimmunology, stress management, and cancer progression/remission;
  7. Psycho-oncological interventions for patients and healthcare professionals;
  8. Promoting early cancer diagnosis and prevention campaigns.

We particularly encourage submissions that address disparities in access to psycho-oncological services, innovative research methodologies, and interdisciplinary collaborations.

Dr. Benedetta Muzii
Prof. Dr. Nelson Mauro Maldonato
Dr. Andrea Bovero
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • psycho-oncology
  • cancer care
  • adaptation process
  • illness experience
  • risk and protective factors
  • mental health care
  • oncofertility
  • palliative care
  • critical experience
  • prevention
  • qualitative and quantitative methods
  • quality of life
  • health behaviors

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Published Papers (1 paper)

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Research

13 pages, 717 KiB  
Article
Stoma Acceptance Mediates Body Image Distress and Mental Health-Related Quality of Life: A Single-Center Study on Radical Cystectomy Patients with Ureterostomy
by Benedetta Muzii, Francesco Di Bello, Claudia Collà Ruvolo, Simone Morra, Federico Polverino, Colomba Pessolano, Massimiliano Creta, Gianluigi Califano, Gabriele Pezone, Francesco Mangiapia, Pierluigi Alvino, Nicola Longo and Nelson Mauro Maldonato
J. Clin. Med. 2024, 13(24), 7682; https://doi.org/10.3390/jcm13247682 - 17 Dec 2024
Cited by 1 | Viewed by 1175
Abstract
Background: Muscle-invasive bladder cancer and subsequent radical cystectomy with ureterocutaneostomy significantly impact patients’ body image and quality of life, potentially increasing the risk of adverse mental health outcomes. Acceptance may represent a psychosocial resource to buffer the effects of body image impairment on [...] Read more.
Background: Muscle-invasive bladder cancer and subsequent radical cystectomy with ureterocutaneostomy significantly impact patients’ body image and quality of life, potentially increasing the risk of adverse mental health outcomes. Acceptance may represent a psychosocial resource to buffer the effects of body image impairment on health, thereby supporting stoma adjustment and preserving quality of life. Objective: This study aimed to investigate the mediating role of stoma acceptance in the relationship between body image distress and mental health. Methods: A single-center cross-sectional survey was conducted with 73 muscle-invasive bladder cancer patients undergoing radical cystectomy with ureterocutaneostomy. Participants completed structured, anonymous self-report measures assessing body image distress, stoma acceptance, and mental health-related quality of life through validated questionnaires. Results: Statistical analyses revealed significant negative correlations between body image distress and mental health and stoma acceptance. Conversely, stoma acceptance was significantly and positively associated with mental health. Regression-based mediation modeling indicated that stoma acceptance exerted a significant mediating effect on the relationship between body image and mental health-related quality of life. Conclusions: These findings highlight the considerable and unprecedented role of stoma acceptance as a mediating factor that may promote the adjustment and enhance the quality of life of urostomy patients. Further research is warranted to explore interventions targeting stoma acceptance to prevent body image distress and promote mental health. Full article
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