POTS, ME/CFS and Long COVID: Recent Advances and Future Direction

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology".

Deadline for manuscript submissions: 20 January 2026 | Viewed by 197

Special Issue Editor


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Guest Editor
Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA
Interests: neurology; autonomic disorders; POTS; long COVID; small fiber neuropathy; autoimmunity; immunotherapy; women’s health
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Special Issue Information

Dear Colleagues,

Postural orthostatic tachycardia syndrome (POTS), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are complex syndromes caused by or associated with the dysfunction of the autonomic nervous system, which can follow an acute infection. Disorders of the autonomic nervous system have been an evolving area of research and clinical practice. In the past 5 years, the SARS-CoV-2 pandemic further underscored the need to elucidate the autonomic mechanisms of post-acute infectious syndromes, such as POTS, ME/CFS and long COVID. To this end, understanding the pathophysiology of and developing diagnostic as well as therapeutic approaches for these three syndromes are critical to improving patient care; they also serve as an opportunity to lead to groundbreaking discoveries in all autonomic disorders and post-acute infectious syndromes. In this Special Issue of the Journal of Clinical Medicine, the aim is to collect papers on a variety of topics concerning POTS, ME/CFS and long COVID. Studies and reviews on the potential biomarkers and identification of effective diagnostic tests as well as therapeutic options  in patients with these disorders are of particular interest.

We look forward to receiving your submissions to this Special Issue.

Dr. Svetlana Blitshteyn
Guest Editor

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Keywords

  • POTS
  • ME/CFS
  • long COVID
  • dysautonomia
  • orthostatic intolerance
  • autoimmunity

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Published Papers

This special issue is now open for submission.
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