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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Skin Cancer: A Closer Look at Non-Melanoma Types
edited by Andrea Paradisi
submission deadline 20 Apr 2026 | 3 articles | Viewed by 2294 | Submission Open
Keywords: basal cell carcinoma; squamous cell carcinoma; actinic keratosis; diagnosis; treatment; non-melanoma skin cancer (NMSC)
(This special issue belongs to the Section Dermatology)
Neuropathic Pain: From Prevention to Diagnosis and Management
edited by Enrico Martin
submission deadline 20 Apr 2026 | 1 articles | Viewed by 2154 | Submission Open
Keywords: neuropathic pain; clinical research; TMR; RPNI; preclinical studies; QoL; PROMS; translational medicine; pain mechanisms
(This special issue belongs to the Section Clinical Neurology)
Advances in the Management of Oral Lichen Planus: A Comprehensive Clinical Perspective
edited by Zuzanna Ślebioda and
submission deadline 20 Apr 2026 | 2 articles | Viewed by 2097 | Submission Open
Keywords: oral lichen planus; treatment; topical treatment; systemic treatment; oral mucosa; oral pathology; immunosuppressive therapy
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Oral Cancer: Clinical Updates and Perspectives submission deadline 20 Apr 2026 | 1 articles | Viewed by 2074 | Submission Open
Keywords: oral cancer; oral surgery; dental implant; tooth extraction; oral health; early detection; biomarkers; targeted therapy; immunotherapy
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Chronic Disease Management and Rehabilitation in Older Adults
edited by
submission deadline 20 Apr 2026 | 2 articles | Viewed by 2034 | Submission Open
Keywords: chronic disease; older adults; geriatric rehabilitation; holistic physiotherapy; physical activity; health outcomes; elderly people; geriatric care; health promotion
(This special issue belongs to the Section Geriatric Medicine)
Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases
edited by and
submission deadline 20 Apr 2026 | 3 articles | Viewed by 2002 | Submission Open
Keywords: echocardiography; cardiac diseases; 3D echo; stress; myocardial strain; intracardiac; subclinical cardiac disease
(This special issue belongs to the Section Cardiology)
Clinical Management of Frailty
edited by , Walter Sepulveda-Loyola and
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1547 | Submission Open
Keywords: frailty; comprehensive geriatric assessment; assessment; monitoring; functional decline; physical performance; ex-ercise interventions; nutritional strategies; interventions; adverse outcomes
(This special issue belongs to the Section Geriatric Medicine)
Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy
edited by , Francesco Costa and Filippo Maria Polli
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1490 | Submission Open
Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g.; kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction
(This special issue belongs to the Section Clinical Neurology)
Current Updates and Advances in Hemodialysis
edited by Edita Žiginskienė
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1433 | Submission Open
Keywords: kidney replacement therapy; hemodialysis; hemodiafiltration; vascular access; dialysis membranes; dialysis complications; dialysis adequacy; outcomes
(This special issue belongs to the Section Nephrology & Urology)
Implant Dentistry: New Challenges and Complication Management
edited by Jordi Gargallo
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1312 | Submission Open
Keywords: navigation surgery; accuracy; computer-aided surgery; computer-assisted; three-dimensional imaging; fixed implant prostheses; zirconia; CAD/CAM; patient satisfaction; peri-implantitis; quality of life; retreatment; tooth loss; connective tissue; keratinized tissue; soft tissue management; bone regeneration; bone grafting; immediate implant placement; immediate implant loading
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Novel Technologies to Assist Emergency Medical Care
edited by and Young Soon Cho
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1265 | Submission Open
Keywords: emergency medical services; artificial intelligence in emergency medicine; telemedicine and remote patient monitoring; wearable health technologies; point-of-care diagnostics; automated decision support systems; robotics in emergency medicine; pre-hospital care innovations
(This special issue belongs to the Section Emergency Medicine)
Respiratory Medicine in the Oldest-Old
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1201 | Submission Open
Keywords: oldest-old; respiratory system with aging; pneumonia; epidemiology; COPD; interstitial lung disease; bronchial asthma; lung cancer; mycobacterial or fungal infections; peri-/post-operative status; respiratory frailty; social problems and end of life
(This special issue belongs to the Section Respiratory Medicine)
Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis
edited by Dong-Ho Kang
submission deadline 20 Apr 2026 | 2 articles | Viewed by 1157 | Submission Open
Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning
(This special issue belongs to the Section Orthopedics)
Preoperative Optimization in Cardiac Surgery
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1079 | Submission Open
Keywords: preoperative optimization; cardiac surgery; risk assessment; comorbid conditions; multidisciplinary collaboration; perioperative risks; cardiovascular evaluation
(This special issue belongs to the Section Cardiology)
Total Joint Arthroplasty: Clinical Advances and Innovations in Surgical Techniques and Rehabilitation
edited by , Marco Minelli and Federico Della Rocca
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1079 | Submission Open
Keywords: total joint arthroplasty; hip replacement; knee arthroplasty; robotic-assisted surgery; minimally invasive techniques; implant design; postoperative rehabilitation; periprosthetic joint infection; surgical innovation
(This special issue belongs to the Section Orthopedics)
Clinical Care and Rehabilitation for Neuromuscular Diseases submission deadline 20 Apr 2026 | 2 articles | Viewed by 983 | Submission Open
Keywords: neuromuscular diseases; myopathy; neuropathy; motor neuron disease; amyotrophic lateral sclerosis; diseases of neuromuscular junction; neurorehabilitation; rehabilitation; clinical care; neuroscience
(This special issue belongs to the Section Clinical Rehabilitation)
Acute Myeloid Leukemia: Latest Advances in Diagnostics, Therapeutic Strategies and Clinical Management: 2nd Edition
edited by Michael D. Diamantidis
submission deadline 20 Apr 2026 | 1 articles | Viewed by 764 | Submission Open
Keywords: ELN; ICC and WHO 2022 AML classifications; molecular AML diagnostics; AML biology; measurable residual disease (MRD); novel targeted AML therapies; AML immunotherapies; hematopoietic stem cell transplantation (HSCT)
(This special issue belongs to the Section Hematology)
Pediatric Dentistry: Real-World Clinical Insights submission deadline 20 Apr 2026 | 1 articles | Viewed by 733 | Submission Open
Keywords: pediatric dentistry; minimally invasive dentistry; new technologies; biomaterials; innovative management approaches; caries management; pulp management; dental trauma; molar incisor hypomineralization; public health services research; epidemiological research; translational research
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Carotid Artery Disease (CAD) and Its Complications: A Comprehensive Update
edited by Yacob G. Tedla
submission deadline 20 Apr 2026 | 1 articles | Viewed by 703 | Submission Open
Keywords: carotid artery disease; ischemic stroke; vascular dementia; transient ischemic attack; vascular imaging; carotid endarterectomy; carotid stent placement; risk stratification
(This special issue belongs to the Section Vascular Medicine)
Clinical Updates in Pediatric Radiology submission deadline 20 Apr 2026 | Viewed by 694 | Submission Open
Keywords: pediatric radiology; advances in pediatric imaging; pediatric neuroimaging; artificial in-telligence in pediatric imaging; radiomics and machine learning; low-field MRI techniques; magnetic resonance imaging in pediatrics; computed tomography in pediatrics; radiation dose optimization; patient-centred imaging protocols
(This special issue belongs to the Section Clinical Pediatrics)
Orofacial Pain: Innovations in Treatment Modalities and Patient Care
edited by Takahiko Nagamine
submission deadline 20 Apr 2026 | 1 articles | Viewed by 673 | Submission Open
Keywords: orofacial pain; treatment; patient care; oral dysfunction; chronic pain; burning mouth syndrome; temporomandibular joint pain: oral cenesthopathy; atypical odontalgia; phantom bite syndrome
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in Maternal Fetal Medicine
edited by and Anna Franca Cavaliere
submission deadline 20 Apr 2026 | 1 articles | Viewed by 635 | Submission Open
Keywords: drugs use during pregnancy; fetal treatment; pregnancy complications; infectious diseases; neonatal poor adaptation syndrome
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Update on Thoracic Trauma
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 519 | Submission Open
Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation
(This special issue belongs to the Section Respiratory Medicine)
Optimizing Outcomes in Emergency Medicine and Cardiopulmonary Resuscitation submission deadline 20 Apr 2026 | 1 articles | Viewed by 519 | Submission Open
Keywords: emergency medicine; cardiopulmonary resuscitation; prehospital care; outcome prediction; post-pesuscitation care; advanced life support; emergency response systems; medical ethics; simulation in medicine
(This special issue belongs to the Section Emergency Medicine)
Recent Advances in Endocrine Surgery—2nd Edition
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 517 | Submission Open
Keywords: endocrine surgery; thyroid; thyroid cancer; parathyroid; parathyroidectomy; adrenal glands; disorders of hepatobiliary and gastrointestinal tract
(This special issue belongs to the Section General Surgery)
Intrarenal Surgery for Kidney Stones and Other Kidney Diseases
edited by Razvan Multescu
submission deadline 20 Apr 2026 | 1 articles | Viewed by 511 | Submission Open
Keywords: intrarenal surgery; flexible ureteroscopy; percutaneous nephrolithotomy (PCNL); Mini-PCNL; thulium laser; ureteral access sheaths; flexible and navigable suction (FANS); upper urinary tract urothelial tumors
(This special issue belongs to the Section Nephrology & Urology)
Clinical Updates in Imaging of Musculoskeletal Diseases submission deadline 20 Apr 2026 | 1 articles | Viewed by 432 | Submission Open
Keywords: musculoskeletal imaging; ultrasound; magnetic resonance; sport imaging; rheumatology; nerve imaging
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Advances and Clinical Outcomes of Endocrinology
edited by Stefana Catalina Bilha and
submission deadline 20 Apr 2026 | Viewed by 260 | Submission Open
Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions
(This special issue belongs to the Section Endocrinology & Metabolism)
Prostate Surgery: The Latest Advances and Future Trends
edited by Akhil K. Das and
submission deadline 20 Apr 2026 | Viewed by 257 | Submission Open
Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP; ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation
(This special issue belongs to the Section Nephrology & Urology)
Ischemic and Hemorrhagic Complications of Uncommon Cerebrovascular Diseases: Cutting-Edge Clinical Research, Reviews, and Expert Opinions
edited by Mariel G. Kozberg and Alexis T. Roy
submission deadline 20 Apr 2026 | Viewed by 250 | Submission Open
Keywords: cerebrovascular disease; ischemic stroke; hemorrhagic stroke; genetics; vasculopathy; headache; superficial siderosis; vascular malformations
(This special issue belongs to the Section Clinical Neurology)
New Insights into Acne Vulgaris Treatment and Management Strategies
edited by Jo Linda Maria Sinagra
submission deadline 20 Apr 2026 | Viewed by 231 | Submission Open
Keywords: acne; hormonal treatments; isotretinoin; laser therapy; antibiotic
(This special issue belongs to the Section Dermatology)
Clinical Updates and Perspectives on Transcranial Magnetic Stimulation (TMS)—2nd Edition submission deadline 20 Apr 2026 | Viewed by 220 | Submission Open
Keywords: non-invasive brain stimulation; transcranial magnetic stimulation; motor cortex; neuroplasticity; motor learning; dementia; stroke; movement disorders; depression; spinal cord; neuropsychiatric disorders
(This special issue belongs to the Section Clinical Neurology)
Interventional Ultrasound Associated with Rehabilitation in the Treatment of Muscolo-Skeletal Disease
edited by Stefano Galletti and
submission deadline 20 Apr 2026 | Viewed by 197 | Submission Open
Keywords: ultrasound; infiltrative treatment; musculoskeletal imaging; rehabilitation; orthopedic; rheumatology; interventional ultrasound
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Global Expert Views on Aortic Valve Repair and Replacement: 2nd Edition submission deadline 20 Apr 2026 | Viewed by 172 | Submission Open
Keywords: aortic valve pathologies; minimally invasive approach; aortic valve repair; aortic valve replacement; imaging techniques
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Oculoplastic Surgery: From Eyelid Reconstruction to Innovative Techniques
edited by Argyrios Tzamalis
submission deadline 20 Apr 2026 | Viewed by 168 | Submission Open
Keywords: oculoplastic surgery; eyelid reconstruction; orbital surgery; novel minimally invasive; image guided
Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition submission deadline 20 Apr 2026 | 1 articles | Viewed by 137 | Submission Open
Keywords: robotic-assisted spine surgery; artificial intelligence (AI); machine learning (ML); cement-augmented pedicle screws; cement leakage risk stratification; osteoporosis pharmacotherapy; surgical navigation systems; image-guided spine surgery; predictive analytics in spine care; spine technology innovation
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Musculoskeletal Pain submission deadline 20 Apr 2026 | Viewed by 127 | Submission Open
Keywords: musculoskeletal pain; chronic pain; primary musculoskeletal pain; secondary chronic musculoskeletal pain; multi-disciplinary pain treatment; imaging in interventional pain management
(This special issue belongs to the Section Orthopedics)
Skin Cancer: Prevention, Diagnosis, Quality of Life and Treatment Outcomes
edited by Athanassios A. Kyrgidis and
submission deadline 20 Apr 2026 | Viewed by 122 | Submission Open
Keywords: skin cancer; melanoma; squamous cell carcinoma; basal cell carcinoma; clinical biomarkers; dermoscopy; quality of life
(This special issue belongs to the Section Dermatology)
Clinical Management for Anesthesia Critical Care
edited by Gianluca Zani
submission deadline 20 Apr 2026 | Viewed by 114 | Submission Open
Keywords: anesthesia; critical care medicine; clinical management; critically ill patients; organ failure; organ dysfunction; per-sonalized therapy; outcome; technical skills; non-technical skills
(This special issue belongs to the Section Anesthesiology)
The Latest Research on Male Infertility
edited by Gianmaria Salvio and Nicola delli Muti
submission deadline 20 Apr 2026 | Viewed by 110 | Submission Open
Keywords: idiopathic male infertility; unexplained male infertility; semen quality; testicular dysfunction; male hypogonadism; gonadal failure
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Advances and Challenges in Head and Neck Reconstructive Surgery
edited by , and Luca Calabrese
submission deadline 20 Apr 2026 | Viewed by 105 | Submission Open
Keywords: reconstructive surgery; head and neck; innovation; microsurgery; virtual surgical planning; 3D-printed implants; tissue engineering
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Heart Failure: Treatment and Clinical Perspectives
edited by Geza Halasz, Domenico Gabrielli and Francesco Grigioni
submission deadline 20 Apr 2026 | Viewed by 104 | Submission Open
Keywords: heart failure; chronic heart failure; acute heart failure; treatment; cardiac imaging; diagnostics; patient outcomes; prognosis
(This special issue belongs to the Section Cardiology)
Hip and Knee Arthroplasty: Update on Clinical Management
edited by Maximilian F. Kasparek
submission deadline 20 Apr 2026 | Viewed by 102 | Submission Open
Keywords: total hip arthroplasty (THA); total knee arthroplasty (TKA); revision arthroplasty; implant fixation; cemented; cementless; hybrid; alignment in TKA; mechanical alignment; kinematic alignment; restricted kinematic alignment; functional alignment; navigation; robotic-assisted surgery; patient-specific instrumentation; additive manufacturing; 3D printing; personalized implant
(This special issue belongs to the Section Orthopedics)
New Insights into Retinal Diseases
edited by Fabio Scarinci and Giulio Pocobelli
submission deadline 20 Apr 2026 | Viewed by 101 | Submission Open
Keywords: optical coherence tomography; optical coherence tomography angiography; vitreoretinal diseases; retinal imaging analysis; biomarkers; segmentation; retinal ischemia; retinal blood flow; choroidal blood flow
(This special issue belongs to the Section Ophthalmology)
Innate Immunity in Overdrive: Novel Insights into Autoinflammatory Syndromes
edited by Alessandro Conforti
submission deadline 20 Apr 2026 | Viewed by 98 | Submission Open
Keywords: autoinflammatory diseases; innate immunity; inflammasome; cytokines; Interleukin-1; monogenic syndromes; polygenic autoinflammatory disorders; adult-onset Still’ s disease; Behç et’ s disease; targeted therapy; disease registries; real-world evidence; VEXAS syndrome; UBA1 mutations; precision medicine; biomarkers; outcome assessment
(This special issue belongs to the Section Immunology & Rheumatology)
Myocardial Infarction: The Latest Advances and Prospects
edited by and Antonios Ziakas
submission deadline 20 Apr 2026 | Viewed by 96 | Submission Open
Keywords: coronary artery disease; myocardial infarction; PPCI; echocardiography; antiplatelet agents; radial access; global longitudinal strain
(This special issue belongs to the Section Cardiology)
Vertebral Fractures and Spinal Cord Injury: Advances in Management
edited by and Martin Stangenberg
submission deadline 20 Apr 2026 | Viewed by 95 | Submission Open
Keywords: fracture management; spinal cord injuries; artificial intelligence; machine learning; spinal trauma
(This special issue belongs to the Section Orthopedics)
Pharmacotherapy of Mental Diseases: Latest Developments submission deadline 20 Apr 2026 | Viewed by 94 | Submission Open
Keywords: brain stimulation; mental health; novel intervention; pharmacotherapy; psychotherapy; quality of life; psychologi-cal well-being; treatment personalization in mental diseases
(This special issue belongs to the Section Mental Health)
New Insights in Joint Arthroplasty—2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 92 | Submission Open
Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA
(This special issue belongs to the Section Orthopedics)
Advances in the Management of Pediatric Neuromuscular Diseases
edited by Nicolas Deconinck
submission deadline 20 Apr 2026 | Viewed by 92 | Submission Open
Keywords: pediatric neuromuscular diseases; neuromuscular disorders (NMD); pediatric; genetic NMD; juvenile myasthenia gravis; chronic demyelinating polyneuropathy; next generation sequencing (NGS); spinal muscular atrophy; Duchenne muscular dystrophy; clinical guidelines
(This special issue belongs to the Section Clinical Neurology)
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