Molecular Immunologic Perspectives on Mycobacterium tuberculosis Infection
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 1660
Special Issue Editor
Interests: mycobacterial diseases; tuberculosis; host immune responses; pathogenesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Infectious disease continues to endanger human lives, causing significant morbidity and mortality worldwide. Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), is believed to have been existence for several thousand years. TB continues to cause 1.6 million deaths every year and 10 million new cases annually worldwide. While the incidence of TB has been steadily decreasing in countries like USA and Canada due to stringent public health measures, the number of active infections caused by non-tuberculous Mycobacteria has increased by more than 100% in these countries, with more than five million deaths in recent years.
Ever since HIV was first discovered in 1981, more than 40 million people have died due to AIDS. Currently, 37 million people are living with HIV infection. Individuals living with HIV with low CD4 T cell counts are increasingly susceptible to M. tb. The pandemic, caused by different variants of SARS-CoV2, has resulted in neglect when it comes to the management of several infectious diseases, including TB and malaria.
The Special Issue will include original articles pertaining to molecular immunologic perspectives on Mycobacterium tuberculosis infection, host–pathogen interactions, and pathogenesis in the context of chronic infections. Articles, case reports, and reviews on the current breakthroughs in this field are highly welcomed.
We welcome articles on the most recent advances in the discovery of novel therapeutic compounds and repurposed drugs that can potentially be utilized against M. tb. We also invite submissions on preclinical research findings obtained from mechanistic studies.
Prof. Dr. Vishwanath Venketaraman
Guest Editor
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Keywords
- M. tb infection
- molecular immunology
- HIV
- AIDS
- pathogenesis
- host immune responses
- adjunctive therapy
- immune-enhancing agents
- antimycobacterial compounds
- host-directed therapies
- pathogenesis
- modulation of host immune responses
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