B Cell Lymphoma: From Pathogenesis to Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 1842
Special Issue Editor
Interests: lymphoma; non-Hodgkin lymphoma; B cell lymphoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lymphomas comprise a heterogeneous group of hematological malignancies classified according to their clinical, anatomopathological, and molecular features. Diffuse large B cell lymphoma (DLBCL) is the most common B cell malignancy worldwide. The incidence of DLBCL increases from 45 cases to 112 per 100,000 people in patients aged 60–64 years and 80–84 years, respectively.
In recent years, numerous genomic sequencing studies have primarily targeted recurrent mutations in individual genes, elucidating underlying oncogenic mechanisms, and recently molecular classifications have deepened our understanding of DLBCL and begun to offer a pathway to improve cure rates by clustering high-risk populations. Therefore, a deeper and detailed analysis using genomic, transcriptome, and epigenetic data has been performed by different groups, refining the classification of DLBCL into clusters with an impact on clinical outcomes. For more than two decades, the combination of rituximab, an anti-CD-20 antibody, and chemotherapy has been the standard of care of such a kind of malignancy, and new options have failed to improve the outcome.
We aim for this Special Issue to cover in-depth reviews and research regarding the role of epigenetic regulation, genes implicated in cell cycle control, proliferation, and apoptosis; the most important biological processes participating in pathogenesis may have an impact on the treatment and outcome of such patients.
Dr. Myrna Gloria Candelaria
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- non-Hodgkin lymphoma pathogenesis
- B cell lymphoma regulation
- epigenetics and B cell lymphoma
- bispecific antibodies in lymphoma
- epigenetics in B cell lymphoma
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
