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Phytochemicals: Molecular Mechanism Research on Antioxidants and Anti-Inflammatory Agents

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 20 May 2025 | Viewed by 1379

Special Issue Editor


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Guest Editor
Institute of Molecular Physiology, Johannes Gutenberg-University Mainz, Hanns-Dieter-Hüsch-Weg 17, D-55128 Mainz, Germany
Interests: natural products; anti-inflammatory; antioxidant; immunostimulant; wound healing; hepatocytes; keratiocytes

Special Issue Information

Dear Colleagues,

Phytochemicals are plant-based bioactive compounds produced by plants. Utilizing these components, which are characterized by low toxicity, abundance, and cost-effectiveness, offers a promising strategy for improving individual health and well-being. Phytochemicals, including flavonoids, phenolic acids, and terpenoids, have attracted significant interest due to their antioxidative and anti-inflammatory properties.

This Special Issue invites papers that investigate the various effects of phytochemicals, including their roles in the following:

  • Scavenging free radicals;
  • Inhibiting inflammatory mediators;
  • Modulating signaling pathways;
  • Identifying molecular targets;
  • Mechanisms underlying their mechanisms of action.

The aim of this Special Issue is to advance our understanding of phytochemicals and their multifaceted roles in health and disease management.

We look forward to your valuable contributions to this Special Issue in the form of original papers, reviews, and short communications.

Dr. Shereen Basiouni
Guest Editor

Manuscript Submission Information

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Keywords

  • phytochemicals
  • bioactive compounds
  • antioxidant
  • anti-inflammatory
  • mechanism of action

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Published Papers (1 paper)

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Research

21 pages, 590 KiB  
Article
Evaluation of Spirulina platensis as a Feed Additive in Low-Protein Diets of Broilers
by Hüseyin Yalçınkaya, Sakine Yalçın, Muhammad Shazaib Ramay, Esin Ebru Onbaşılar, Buket Bakır, Fatma Kübra Erbay Elibol, Suzan Yalçın, Awad A. Shehata and Shereen Basiouni
Int. J. Mol. Sci. 2025, 26(1), 24; https://doi.org/10.3390/ijms26010024 - 24 Dec 2024
Viewed by 905
Abstract
Spirulina platensis is a natural antioxidant product that has the ability to improve the performance of poultry. Therefore, the present study aimed to evaluate the effect of using Spirulina platensis as a feed additive in broiler diets. A total of 252 daily male [...] Read more.
Spirulina platensis is a natural antioxidant product that has the ability to improve the performance of poultry. Therefore, the present study aimed to evaluate the effect of using Spirulina platensis as a feed additive in broiler diets. A total of 252 daily male Ross 308 chicks were randomly assigned to six groups. There were two different protein groups: one was at the catalog protein value, and the other was reduced by 10%. Spirulina platensis at 0, 0.1, and 0.2% was added to each protein group. The trial lasted 41 days. Reducing the protein level by 10% had a negative impact on the performance of the chicks. However, Spirulina platensis supplementation had a positive effect on the feed conversion ratio, reduced the oxidative stress index in the chicks’ liver and meat, increased the total antioxidant status and antioxidant enzyme activities, improved the villus height, serum IgG, and some bone parameters, and reduced the serum triglyceride concentration. The carcass yield, visceral organ weight percentages, total phenolic content, and malondialdehyde (MDA) level in the thigh meat and some serum biochemical parameters were not affected by the usage of Spirulina platensis. In conclusion, 0.1% Spirulina platensis could be a feasible feed additive in low-protein diets due to eliciting an improved performance, antioxidant status, and immune response in broilers. Full article
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