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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Properties and Applications of Nanoparticles and Nanomaterials: 4th Edition
edited by Xiaogang Li
submission deadline 10 Sep 2026 | Viewed by 373 | Submission Open
Keywords: nanostructures; nanoparticles; microstructure characterization; material design; evaluation of mechanical properties; applications of nanomaterials
(This special issue belongs to the Section Molecular Nanoscience)
Nanomaterials for Targeted Therapy and Drug Delivery
edited by Ceren Kimna
submission deadline 10 Sep 2026 | Viewed by 190 | Submission Open
Keywords: nanocarriers  ; targeted therapies  ; translational nanomedicine  ; nano-bio interactions
(This special issue belongs to the Section Molecular Nanoscience)
Pain: From Bench to Bedside
edited by and Robert J. Yong
submission deadline 20 Sep 2026 | 1 articles | Viewed by 41095 | Submission Open
Keywords: CGRP pathway; chronic pain; drug discovery; ion channels; machine learning; molecular targets; neuroimmune signaling; non-opioid analgesics; translational pain research     TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Autoimmune Diseases: From Pathogenesis to Treatment and Prognostic Markers
edited by Alessandra Bettiol
submission deadline 20 Sep 2026 | 12 articles | Viewed by 36354 | Submission Open
Keywords: autoimmune diseases; inflammation; immunity; pathogenesis; immunosuppressants; biologics; biomarkers
(This special issue belongs to the Section Molecular Immunology)
Drug Delivery to the Central Nervous System: From Design, Synthesis, and Evaluation
edited by
submission deadline 20 Sep 2026 | 6 articles | Viewed by 35338 | Submission Open
Keywords: central nervous system; central nervous system diseases; drug delivery systems; blood– brain barrier; blood– cerebrospinal fluid barrier; drug design; nanomedicine; neuropharmacology; neuroprotective agents; biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
Plant Metabolomics: Uncovering the Hidden World of Plant Secondary Metabolites
edited by
submission deadline 20 Sep 2026 | 13 articles | Viewed by 30060 | Submission Open
Keywords: metabolomics; secondary metabolites; plant biochemistry; mass spectrometry; NMR spectroscopy; plant signaling pathways; natural products; chemical ecology; metabolic profiling; phytochemicals; medicinal plants; herbal medicines
(This special issue belongs to the Section Molecular Plant Sciences)
New Insights in Antibody Therapy
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 18038 | Submission Open
Keywords: biological therapy; antibody therapy; non-communicable diseases; infectious diseases; chronic disease
(This special issue belongs to the Section Molecular Immunology)
Renin-Angiotensin System in Health and Diseases
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 15849 | Submission Open
Keywords: coronavirus disease 2019 (COVID-19); SARS-CoV-2; RAAS; spike protein; angiotensin; ACE2; clinical study; basic experiments
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Type 2 Diabetes: Molecular Pathophysiology and Treatment
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 14562 | Submission Open
Keywords: type 2 diabetes mellitus and comorbidity; bioinformatics; molecular pathways; genetic background; biomarkers; novel therapies
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Burn Wound Healing and Skin Regeneration: Innovations and Insights
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 14160 | Submission Open
Keywords: burn wound healing; skin regeneration; novel biomaterials; wound dressings; regenerative therapies
(This special issue belongs to the Section Biochemistry)
Inflammation in Chronic Disease: Molecular Mechanisms and Signaling Pathways
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 12601 | Submission Open
Keywords: inflammation; neuroinflammation; immune response; inflammation-associated disease; inflammation mediators (proteins; enzymes; ecc); cytokines; macrophages; mast cells; monocytes; dendritic cells; oxidative stress; signaling pathways
(This special issue belongs to the Section Molecular Immunology)
Cancer Drug Treatment and Cancer Cell Drug Resistance submission deadline 20 Sep 2026 | 3 articles | Viewed by 12552 | Submission Open
Keywords: cellular plasticity; heterogeneity; combinational chemotherapy; metastasis; tumor relapse; novel targets; drug delivery
(This special issue belongs to the Section Molecular Pharmacology)
Advances in Computer-Aided Drug Design Strategies submission deadline 20 Sep 2026 | 3 articles | Viewed by 12407 | Submission Open
Keywords: computer-aided drug design; artificial intelligence in drug discovery; molecular docking; molecular dynamics simulations; macromolecular systems; quantum mechanics/molecular mechanics (QM/MM); big data analytics in drug development; pharmacokinetics optimization; structure-based drug design (SBDD); ligand-based drug design; virtual screening techniques
(This special issue belongs to the Section Molecular Informatics)
Understanding Aging in Health and Disease
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 11911 | Submission Open
Keywords: immunosenescence; age-related disease; ageing; oxidative stress; inflammaging
(This special issue belongs to the Section Molecular Biology)
Progression of Multiple Sclerosis: Environmental Factors, Genetics, Therapeutics and Immunopathogenesis
edited by Alberto Gajofatto
submission deadline 20 Sep 2026 | 4 articles | Viewed by 11751 | Submission Open
Keywords: multiple sclerosis; disability progression; neurodegeneration; pathogenesis; immunology; risk factor; environment; genetics; treatment
(This special issue belongs to the Section Molecular Neurobiology)
Advances in the Genetics, Epidemiology and Management of Myopathies submission deadline 20 Sep 2026 | 2 articles | Viewed by 11579 | Submission Open
Keywords: myopathies; muscle disorders; muscle weakness; muscle pain; myalgia
(This special issue belongs to the Section Molecular Biology)
Molecular Research of Dystonia and Parkinson’s Disease
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 11241 | Submission Open
Keywords: dystonia; Parkinson’ s disease; molecular mechanism; molecular pathology; cell biology; genetic predisposition to disease; physiopathology; neural plasticity; animal models; biomedical translational science
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Identification of Novel Biomarkers Towards Improved Diagnosis and Management of Peripheral Vascular Diseases
edited by
submission deadline 20 Sep 2026 | 6 articles | Viewed by 10971 | Submission Open
Keywords: vascular pathophysiology; peripheral atherosclerosis; aneurysm; venous disorders; congenital vascular malformations; molecular biomarkers; diagnostic biomarkers; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Antibody Engineering and Therapeutic Applications
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 10632 | Submission Open
Keywords: monoclonal antibody (mAb) therapies; antibody engineering; antibody-drug conjugate (ADC); chimeric antigen receptor T cell (CAR-T); bispecific antibody; T-cell engager (TCE); cancer immunotherapy; immunocytokine; AI-driven antibody design; antibody structure and mechanism of action
(This special issue belongs to the Section Molecular Pharmacology)
25th Anniversary of IJMS: Advances in Physical Chemistry and Chemical Physics submission deadline 20 Sep 2026 | 10 articles | Viewed by 10194 | Submission Open
Keywords: molecular dynamics; quantum chemistry; spectroscopic techniques; supramolecular interactions; computational modeling; AI in chemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Parkinson’s Disease and Related Diseases: Mechanisms, Genetic Factors and Treatments
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 10105 | Submission Open
Keywords: Parkinson’ s disease; neurodegenerative disorders; α -synuclein aggregation; neuroinflammation; gene therapy; biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
Artificial Intelligence and Computer-Aided Design: Molecular Simulation Technology in Exploring Bioactive Compounds for Health Promotion
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 9978 | Submission Open
Keywords: molecular simulation; bioactive compounds; molecular docking; molecular dynamics; quantum mechanics; functional mechanisms
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Latest Advances in Diabetes Research and Practice
edited by Ezekiel Uba Nwose
submission deadline 20 Sep 2026 | 5 articles | Viewed by 9904 | Submission Open
Keywords: diabetes mellitus; cardiovascular risk; metabolic syndrome; antioxidants; oxidative stress; antiplatelet monitoring; evidence-based medicine; laboratory medicine
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
The Structures, Syntheses of Natural Products, and Their Biological Effects
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 9651 | Submission Open
Keywords: structures of natural products; syntheses; biological effects; biomedical applications
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Neurological Diseases: From Pathogenesis to Molecular Diagnosis and Treatment submission deadline 20 Sep 2026 | 10 articles | Viewed by 9299 | Submission Open
Keywords: Alzheimer's disease; Parkinson's disease; Huntington's disease; epilepsy; stroke; neurological diseases; treatment of neurological diseases
(This special issue belongs to the Section Molecular Neurobiology)
Melanin and Other Pigments: Function, Synthesis and Characterization
edited by Koen P. Vercruysse
submission deadline 20 Sep 2026 | 4 articles | Viewed by 9074 | Submission Open
Keywords: melanin; eumelanin; pheomelanin; allomelanin; catechol; indole; phenol
(This special issue belongs to the Section Biochemistry)
Inflammation in Pregnancy and Childbirth
edited by and Maciej Ziętek
submission deadline 20 Sep 2026 | 2 articles | Viewed by 9052 | Submission Open
Keywords: pregnancy; labor; eicosanoid; chronic inflammation; cytokines; intestinal dysbiosis; mitogen-activated protein kinase; nuclear factor kappa-light-enhancer-activated B cell; maresins; resolvins and protectins
(This special issue belongs to the Section Molecular Immunology)
Elucidating How Chondrocytes Maintain Cartilage Stability
edited by James A. Martin
submission deadline 20 Sep 2026 | 4 articles | Viewed by 8812 | Submission Open
Keywords: chondrocytes; articular cartilage; chondrogenesis; osteoarthritis; mechano-transduction; aging; extracellular matrix
(This special issue belongs to the Section Molecular Biology)
Bioactive Molecules from Food or Other Natural Sources Against Cancer: 2nd Edition submission deadline 20 Sep 2026 | 3 articles | Viewed by 8696 | Submission Open
Keywords: cancer; natural bioactive molecules; natural products; tumor
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Biosynthesis of Phytochemicals and Their Applications in Novel Drug Lead Development
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 8578 | Submission Open
Keywords: biosynthesis of phytochemicals in plants; phytochemical isolation; phytochemical structure; animal and human protein targets of phytochemicals; chemical derivatives of phytochemicals
(This special issue belongs to the Section Molecular Pharmacology)
Medicinal Plant Resources—from Molecular Studies to Sustainable Use
edited by Ekaterina Kozuharova
submission deadline 20 Sep 2026 | 3 articles | Viewed by 8403 | Submission Open
Keywords: genetic improvement of medicinal plants; sustainable use; bioactive compounds
(This special issue belongs to the Section Molecular Plant Sciences)
Recent Advances in Immunosuppressive Therapy
edited by
submission deadline 20 Sep 2026 | 2 articles | Viewed by 8315 | Submission Open
Keywords: immunosuppressive drugs; calcineurin inhibitors; corticosteroids; inhibitors of purine synthesis; mammalian target of rapamycin inhibitors; biological treatment; cell-based therapies; biomarkers; genetic profiling
(This special issue belongs to the Section Molecular Immunology)
From Macrophage Biology to Cell and EV-Based Immunotherapies submission deadline 20 Sep 2026 | 2 articles | Viewed by 8215 | Submission Open
Keywords: macrophage-based; macrophage-targeting; cancer immunotherapies; autoimmunity
(This special issue belongs to the Section Molecular Immunology)
The Role of Bioactive Compounds in Human Health and Disease: 3rd Edition
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 8014 | Submission Open
Keywords: cancer; inflammation; cardiovascular diseases; plants; bioactive compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Inner Ear Disorders: From Molecular Mechanisms to Treatment
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 7980 | Submission Open
Keywords: hearing loss; balance disorders; stem cell approaches; precision gene therapy; molecular reprogramming; targeted delivery systems; molecular biomarkers; suppression of oxidative stress and inflammation; tissue engineering; immune response and off-target effects
(This special issue belongs to the Section Molecular Immunology)
Molecular Advances in Regenerative Medicine and Therapeutics
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 7685 | Submission Open
Keywords: regenerative medicine; morphology; regenerative dentistry; biomaterials; scaffolds; organoids; tissue regeneration
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cellular and Molecular Study of Neurodevelopmental and Neurological Disorders
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 7612 | Submission Open
Keywords: autism spectrum disorder; ADHD; schizophrenia; intellectual disability; Alzheimer’ s disease; Parkinson’ s disorder; traumatic brain injury; epilepsy; neurodevelopmental disorders; neurological diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring the Complex Interplay Between Metabolic Diseases, MASLD, and Liver Cancer submission deadline 20 Sep 2026 | 4 articles | Viewed by 7443 | Submission Open
Keywords: hepatocellular carcinoma; MASLD; MASH; obesity; insulin resistance; dyslipidemia; liver cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Advances in Metabolic Engineering and Synthetic Biology of Yeasts
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 7424 | Submission Open
Keywords: yeast metabolic engineering; synthetic biology; CRISPR-Cas9; metabolic pathways; bio-based chemicals; bioprocess engineering; yeast strain optimization; industrial biotechnology
(This special issue belongs to the Section Molecular Microbiology)
Molecular Pharmacology and Interventions in Cardiovascular Disease: 2nd Edition submission deadline 20 Sep 2026 | 5 articles | Viewed by 7385 | Submission Open
Keywords: cardiovascular pharmacology; cardiovascular interventions; cardioprotection; myocardial ischemia and infarction; heart failure
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms, Pathogenesis, and Novel Therapeutic Strategies in Cardiovascular Disease, 2nd Edition
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 7187 | Submission Open
Keywords: aneurysm pathobiology; vascular remodeling; extracellular matrix degradation; inflammatory signaling pathways; molecular targets for therapy; autophagy; macrophage; inflammation; immune cell regulation; age-related diseases; therapeutic implications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Neutrophil Extracellular Traps (NETs) in Immunity and Diseases, 3rd Edition
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 7143 | Submission Open
Keywords: neutrophils; neutrophil functions; neutrophil extracellular traps (NETs); NET biology; NETs in autoimmune diseases; NETs in immune response; NETs in the development and progression of cancer diseases; NETs in immunothrombosis; degradation of NETs
(This special issue belongs to the Section Molecular Immunology)
New Challenges of Parkinson’s Disease, 2nd Edition submission deadline 20 Sep 2026 | 5 articles | Viewed by 6846 | Submission Open
Keywords: Parkinson’ s disease; neurodegeneration; synuclein; diagnosis; genetics; epigenetics; extracellular vesicles; biomarkers; treatments; rehabilitation
(This special issue belongs to the Section Molecular Neurobiology)
Gluten/Wheat-Related Disorders: The Role of Nutrition, Gut Barrier, Microbiota, and New Therapeutic Strategies
edited by Lisa Lungaro
submission deadline 20 Sep 2026 | 2 articles | Viewed by 6837 | Submission Open
Keywords: gluten-related disorders; celiac disease; non celiac gluten wheat sensitivity; gluten free diet; microbiota; gut barrier; probiotics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Dialogue Between Inflammation and Immunity: From Mechanism to Therapy
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 6837 | Submission Open
Keywords: inflammation; immune activation; immunomodulation; tolerance; immunotherapy; autoimmune diseases; cancer
(This special issue belongs to the Section Molecular Immunology)
Molecular Aspects of Forensic Toxicology
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 6664 | Submission Open
Keywords: forensic toxicology; molecular mechanism; toxicological biomarkers; post-mortem interval; in vitro; in vivo; and in silico models; new psychoactive substances (NPSs); new synthetic opioids; liquid chromatography-high resolution mass spectrometry (LC-HRMS/MS); liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-tandem mass spectrometry (GC-MS/MS)
(This special issue belongs to the Section Molecular Toxicology)
Molecular Mechanisms of the Aging Process: 2nd Edition submission deadline 20 Sep 2026 | 1 articles | Viewed by 6650 | Submission Open
Keywords: aging process; molecular mechanisms; epigenetic clock; cancer; metabolic disease
(This special issue belongs to the Section Molecular Biology)
Aging: From Molecular Mechanisms and Pathophysiology to Novel Therapeutic Approaches (3rd Edition) submission deadline 20 Sep 2026 | 5 articles | Viewed by 6372 | Submission Open
Keywords: human aging; molecular clock; aging genes; epigenetics; nutrigenomics; inflammaging; stem cells; telomeres; mitochondria; brain-gut axis; brain-muscle axis; gut microbiota; chronodisruption
(This special issue belongs to the Section Molecular Biology)
Advanced Molecular Research in Brain Tumors
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 6347 | Submission Open
Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME
(This special issue belongs to the Section Molecular Oncology)
Bee Products and Their Flavonoids: Recent Advances in Molecular Mechanisms, Therapeutic Applications, and Innovative Delivery Systems submission deadline 20 Sep 2026 | 2 articles | Viewed by 6189 | Submission Open
Keywords: honeybee products; flavonoids; bioactive compounds; biological activity; pharmacological activity; health benefits; side effects; disease prevention; antioxidant activity; apitherapy; nutritional properties; innovative technical approaches
(This special issue belongs to the Section Molecular Biology)
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