Identification of Novel Biomarkers Towards Improved Diagnosis and Management of Peripheral Vascular Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 619
Special Issue Editor
Interests: peripheral artery disease; chronic venous disease; aortic aneurysm; biomarker discovery; microRNA; gene expression profiling; visualisation and analysis of biological data in R
Special Issue Information
Dear Colleagues,
Diseases affecting peripheral vasculature (outside the coronary and cerebral circulation) encompass a variety of disorders, including atherosclerotic diseases (e.g., peripheral artery disease), venous disorders (e.g., chronic venous disease), aneurysmal diseases (e.g., abdominal aortic aneurysm), and congenital vascular malformations (e.g., Klippel-Trénaunay-Weber syndrome). Most of these diseases significantly impairs quality of life and are associated with severe morbidity and mortality. Despite advances in medical science, they continue to represent a substantial public health challenge. Current diagnostic modalities are often insufficiently sensitive or specific, missing many at-risk individuals during the early stages and leading to delayed or suboptimal interventions.
The identification of new molecular biomarkers for peripheral vascular diseases is critical for improving early detection, risk stratification, and personalised treatment strategies, addressing limitations of traditional diagnostic tools. Novel biomarkers can provide insights into underlying pathophysiological mechanisms, enabling more accurate prognostic assessments and facilitating the development of targeted therapies to reduce disease burden and improve patient outcomes.
This special issue invites articles from molecular research focused on the identification of novel biomarkers (at the levels of genome, epigenome, transcriptome, and proteome) with potential usefulness as diagnostic and therapeutic targets for peripheral vascular diseases.
Dr. Daniel P. Zalewski
Guest Editor
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Keywords
- vascular pathophysiology
- peripheral atherosclerosis
- aneurysm
- venous disorders
- congenital vascular malformations
- molecular biomarkers
- diagnostic biomarkers
- therapeutic targets
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