The Structures, Syntheses of Natural Products, and Their Biological Effects
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: closed (30 April 2025) | Viewed by 1552
Special Issue Editor
Interests: density functional theory; nanotechnology; materials; electronic structure; quantum mechanics; nanobiotechnology; computational chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The applications of natural products already have a long history of thousands of years; however, most cases were empirical summaries. With the continuous progress of science and technology, people have begun to systematically study the structures and biological effects of natural products using scientific methods to understand their working mechanisms and obtain them in large quantities through artificial syntheses. Many natural medicinal molecules have special therapeutic effects in animals and plants.
As the most typical example, Artemisinin's discovery, extraction, and structural determination have significant implications for human public health, bringing Ms. Youyou Tu the Nobel Prize in 2015. With the deepening of research, other effects of Artemisinin have also been found, such as anti-tumor, treatment of pulmonary hypertension, anti-diabetes, antifungal, immune regulation, antiviral, anti-inflammatory, anti-pulmonary fibrosis, antibacterial, and other pharmacological effects. However, its chemical total synthesis process is so complex that it cannot be commercialized. Fortunately, the biosynthesis technology through yeast fermentation is becoming increasingly sophisticated. Similar efficient natural products also include (but are not limited to) organic acids, antimicrobial peptides, biological adhesives, and so on. The studies of their molecular structures, structure–activity relationships, and syntheses are of great scientific and economic significance.
Therefore, we are launching this Special Issue to specifically report on the latest research and reviews on the structures and syntheses of natural products and their biological effects. All article research submissions should involve research at the molecular level as well as verified experiments to fit the scope of the Special Issue.
Dr. Ran Jia
Guest Editor
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Keywords
- structures of natural products
- syntheses
- biological effects
- biomedical applications
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