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Molecular Mechanisms, Pathogenesis, and Novel Therapeutic Strategies in Cardiovascular Disease, 2nd Edition

Special Issue Editor


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Guest Editor
Division of Vascular Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA
Interests: aneurysm; vascular biology; angiogenesis; intimal hyperplasia; macrophage; osteoclastogenesis; MMPs
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Aneurysms, characterized by the localized dilation of blood vessels, pose a significant health risk due to the potential for rupture and life-threatening hemorrhage. In recent years, there has been growing interest in understanding the molecular mechanisms underlying the development and progression of aneurysms. This Special Issue aims to highlight recent advances in aneurysm research, focusing on the molecular aspects of aneurysm formation, progression, and novel therapeutic strategies.

In this Special Issue of the International Journal of Molecular Sciences, we invite authors to submit original research articles, reviews, and perspectives that delve into the molecular underpinnings of aneurysm formation and progression, specifically in relation to cardiovascular disease. Topics of interest include, but are not limited to, vascular remodeling, extracellular matrix degradation, the role of inflammatory signaling pathways, and the identification of novel molecular targets for therapy.

We particularly encourage submissions that provide in-depth insights into the molecular mechanisms of aneurysm pathobiology and the intricate interplay between various cellular and molecular factors contributing to aneurysm development. Contributions exploring innovative therapeutic approaches, such as gene therapy, stem cell therapy, and pharmacological interventions targeting specific molecular pathways, are also welcome.

By assembling a diverse collection of high-quality articles, this Special Issue aims to advance our understanding of the complex molecular landscape governing aneurysm formation and progression in cardiovascular disease and to inspire further research in this rapidly evolving field.

Dr. Dai Yamanouchi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aneurysm pathobiology
  • vascular remodeling
  • extracellular matrix degradation
  • inflammatory signaling pathways
  • molecular targets for therapy
  • autophagy
  • macrophage
  • inflammation
  • immune cell regulation
  • age-related diseases
  • therapeutic implications

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