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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Age-Dependence of Neuroimmune Reactions

edited by

Babak Baban

submission deadline 31 Jul 2025 | Viewed by 67 | Submission Open

Keywords: age; neuroimmune dynamics; neuroimmune interaction; immune system; the central nervous system; age-related neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Molecular Immunology)

Molecular Advanced of Layered Double Hydroxides (LDH) for Corrosion Protection

edited by

Henryk Kania

submission deadline 31 Jul 2025 | Viewed by 67 | Submission Open

Keywords: layered double hydroxide (LDHs); corrosion resistance; coatings; corrosion products

(This special issue belongs to the Section Materials Science)

Extracellular Vesicles: Unraveling Molecular Pathways for Targeted Therapy

edited by

Ssang-Goo Cho

submission deadline 31 Jul 2025 | Viewed by 66 | Submission Open

Keywords: stem cells; cellular reprogramming; extracellular vesicles; exosomes; targeted therapy; regenerative medicine; rejuvenation; anti-inflammation therapy; pain syndrome

(This special issue belongs to the Section Molecular Biology)

Advancing Precision Medicine in Urological Cancers: Integrating Multi-Omics and Optimizing Therapeutic Approaches

edited by Magaly Martinez-Ferrer

submission deadline 31 Jul 2025 | Viewed by 66 | Submission Open

Keywords: prostate cancer; proteomics; metabolomics; precision medicine; biomarker

(This special issue belongs to the Section Molecular Oncology)

New Research on the Biological Activities of Natural Components and Their Application

edited by

Željana Fredotović

submission deadline 31 Jul 2025 | Viewed by 65 | Submission Open

Keywords: natural compounds; traditional and medicinal plants; biological activities

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Extracellular Vesicles as Biomarkers in Personalized Medicine

edited by Thi Thuy Nguyen Dao

submission deadline 31 Jul 2025 | Viewed by 65 | Submission Open

Keywords: extracellular vesicles; biomarkers; cancer; cardiovascular diseases; neurodegenerative diseases; personalized medicineg

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Genetics, Genomics and Breeding in Field Crops

edited by

Xianzhong Feng

submission deadline 31 Jul 2025 | Viewed by 65 | Submission Open

Keywords: field crop; genomics; molecular genetics; breeding technologies; germplasm utilization

(This special issue belongs to the Section Molecular Plant Sciences)

Progress in Spectroscopic Studies of Biomolecules

edited by

Mahmoud Ghomi

submission deadline 31 Jul 2025 | Viewed by 64 | Submission Open

Keywords: spectroscopic; nuclear magnetic resonance; X-ray; neutron scattering; biomolecular structure

(This special issue belongs to the Section Molecular Biophysics)

Molecular Research in Epilepsy and Epileptogenesis—2nd Edition

edited by

Stanisław Jerzy Czuczwar

submission deadline 31 Jul 2025 | Viewed by 64 | Submission Open

Keywords: epilepsy; antiseizure; anti-epileptogenic drugs; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Musculoskeletal Injuries and Conditions: From Pathophysiology to Novel Therapeutic Approaches

edited by

Jai-Hong Cheng

submission deadline 31 Jul 2025 | Viewed by 60 | Submission Open

Keywords: musculoskeletal disorder; pathophysiology; diagnosis; biomarkers; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Molecular Diagnosis and Treatment of Neurodegenerative Diseases

edited by

Bruno Manadas

submission deadline 31 Jul 2025 | Viewed by 54 | Submission Open

Keywords: neurodegenerative disorders; biomarkers; treatment; omics; systems biology

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Molecular Research on Axon Demyelination and Remyelination

edited by Rachelle Frazen

submission deadline 31 Jul 2025 | Viewed by 52 | Submission Open

Keywords: myelin; Schwann; OPC/oligodendrocytes; axon— glia crosstalk; peripheral neuropathies; multiple sclerosis; remyelination; myelin maintenance; molecular targets; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Impact of Vitamins on Cardiovascular Disease

edited by León Ferder

submission deadline 31 Jul 2025 | Viewed by 50 | Submission Open

Keywords: vitamins; cardiovascular disease; atherosclerosis; hypertension; heart failure; endothelial dysfunction; mitochondrial metabolism; oxidative stress; longevity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Light-On Molecular Probes for Biomedical Analysis

edited by Aleksey A. Vasilev

submission deadline 31 Jul 2025 | Viewed by 46 | Submission Open

Keywords: fluorogenic dyes; nucleic acid binders; nucleic acid labels; molecular probes; fluorogenic polymers and nanomaterials

(This special issue belongs to the Section Materials Science)

Galectins (Gals), 2nd Edition

edited by

Luciano Pirone

submission deadline 10 Aug 2025 | 2 articles | Viewed by 867 | Submission Open

Keywords: galectin; inhibitors; cancer; inflammation; glycans; drug design; modeling; biomarkers

(This special issue belongs to the Section Molecular Biology)

Molecular Characterization and Applications of Nanomaterials in Nanomedicine and Cancer Therapy

edited by

Costica Caizer

submission deadline 15 Aug 2025 | 1 articles | Viewed by 718 | Submission Open

Keywords: nanomaterials (preparation methods; characterization techniques; properties); theoretical studies of nanomaterials and computational simulations; biocompatibility and biofunctionalization; applications in nanomedicine; applications in cancer therapy; drug delivery; nanoparticle imaging; magnetic resonance imaging (MRI); contrast agents; nanotheranostics

(This special issue belongs to the Section Molecular Nanoscience)

Anti-Cancer, Anti-Inflammatory, and Antioxidation Active Substances: 3rd Edition

edited by

Ming-Ju Hsieh

submission deadline 15 Aug 2025 | 1 articles | Viewed by 641 | Submission Open

Keywords: anti-inflammatory; anti-cancer; antioxidants; antiproliferative; antiviral; antibacterial; antibodies; molecular mechanism; chemoresistance; molecular biology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular and Cellular Therapies Barriers and Opportunities

edited by

O’neil W. Guthrie

submission deadline 15 Aug 2025 | Viewed by 99 | Submission Open

Keywords: gene therapy; gene editing; RNA therapy; RNA editing; protein therapy; stem cells; cell therapy; genomics; proteomics; molecular pathology

(This special issue belongs to the Section Molecular Biology)

The Role of the Gut and Oral Microbiota in Neurodevelopment: Molecular Biological Insights

edited by Ioannis Alexandros Charitos

submission deadline 15 Aug 2025 | Viewed by 55 | Submission Open

Keywords: neuroscience; central nervous system; peripheral nervous system; human microbiota; metabolome; gut– oral-microbiota– brain axis; neurodevelopment disorders; cognitive modulation; neurodegenerative diseases; psychobiotics

(This special issue belongs to the Section Molecular Microbiology)

Novel Therapeutic Strategies for Gynecological Cancer

edited by

Masayuki Sekine

submission deadline 15 Aug 2025 | Viewed by 48 | Submission Open

Keywords: gynecological cancer; therapeutic strategies; genomic medicine; multimodality treatment; biomarker; molecular targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Pathologies and Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

edited by

Elisa Oltra

submission deadline 20 Aug 2025 | 2 articles | Viewed by 26483 | Submission Open

Keywords: myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); diagnosis; post-exertional malaise (PEM); comorbidity; biomarker; therapy; immunity; microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Targeted Therapies of Breast Cancer

edited by

Piotr Dzięgiel

, Karolina Jabłońska and

Katarzyna Nowińska

submission deadline 20 Aug 2025 | 8 articles | Viewed by 24557 | Submission Open

Keywords: breast cancer; cancer progression; cancer metastasis; tumor microenvironment; molecular mechanisms; molecular markers; epigenetics; genomics; transcriptomics; EMT; targeted therapies; signaling pathways; exosomes; EMT; hormonal regulation; drugs; apoptosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Retinal Degenerative Diseases: 2nd Edition

edited by

Diego García-Ayuso

and

Johnny Di Pierdomenico

submission deadline 20 Aug 2025 | 5 articles | Viewed by 20216 | Submission Open

Keywords: retina; photoreceptor degenerative diseases; inherited retinal degenerations; glaucoma; retinal pigment epithelial cells; retinal ganglion cells (RGCs); neuronal degeneration; glial activation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Metabolomics: Uncovering the Hidden World of Plant Secondary Metabolites

edited by

Jen-Tsung Chen

submission deadline 20 Aug 2025 | 12 articles | Viewed by 16836 | Submission Open

Keywords: metabolomics; secondary metabolites; plant biochemistry; mass spectrometry; NMR spectroscopy; plant signaling pathways; natural products; chemical ecology; metabolic profiling; phytochemicals; medicinal plants; herbal medicines

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Bioactive Nutrients Promoting Human Health

edited by

Baojun Xu

submission deadline 20 Aug 2025 | 9 articles | Viewed by 15351 | Submission Open

Keywords: bioactive nutrients; antioxidants; anti-inflammatory; disease prevention; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of Trace Elements in Nutrition and Health

edited by Jie Feng

submission deadline 20 Aug 2025 | 7 articles | Viewed by 14212 | Submission Open

Keywords: trace elements; nutrition; health; function; disease; metabolism; homeostasis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Skin Cancer Pathology: From Pathogenesis to Precision Therapies

edited by

Ovidiu Simion Cotoi

submission deadline 20 Aug 2025 | 4 articles | Viewed by 14050 | Submission Open

Keywords: skin cancer; melanoma; non-melanoma; immunotherapy; cutaneous malignancies; targeted therapy; early detection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Links between Sensory Nerves, Inflammation, and Pain 3.0

edited by

Zsuzsanna Helyes

and

Szőke Éva

submission deadline 20 Aug 2025 | 5 articles | Viewed by 13464 | Submission Open

Keywords: sensory neuropeptides; inflammation; neurogenic inflammation; pain; arthritis; colitis; neuropathy; migraine; novel drug targets; TRP channels; neuroinflammation

(This special issue belongs to the Section Molecular Biology)

Cytokines in Inflammatory Signaling: 2nd Edition

edited by

Waipo Chong

Daniela Novick

and

Rosalinda Sorrentino

submission deadline 20 Aug 2025 | 7 articles | Viewed by 13090 | Submission Open

Keywords: cytokines; inflammation; autoimmune diseases; immune homeostasis; signaling pathway; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Advances in Neurodegenerative Diseases Research and Therapy—Third Edition

edited by

Sumonto Mitra

submission deadline 20 Aug 2025 | 7 articles | Viewed by 12730 | Submission Open

Keywords: neurodegenerative diseases; therapy; molecular mechanisms; neuron; astrocytes; microglia; inflammation; brain; drug delivery

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Research of Skin Inflammation and Related Diseases

edited by

Filomena Napolitano

and

Valentina Giudice

submission deadline 20 Aug 2025 | 6 articles | Viewed by 12557 | Submission Open

Keywords: skin; inflammation; molecular target; inflammatory skin diseases; psoriasis; urticaria; atopic dermatitis; systemic sclerosis; skin fibrosis; immune system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Targeted Therapies and Drugs in Cancer

edited by

Maria Teresa Vietri

submission deadline 20 Aug 2025 | 5 articles | Viewed by 12235 | Submission Open

Keywords: targeted therapies; genetic mutation; PARP inhibitors; immunotherapy; drug development; cancer molecular analysis; drug response; molecular-targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exercise and Health: Cellular and Molecular Perspectives

edited by

Annamaria Mancini

submission deadline 20 Aug 2025 | 4 articles | Viewed by 12125 | Submission Open

Keywords: promoting health; anti-inflammatory action; anti-ageing action; mental health; mitochondrial adaptation; cellular function; regulation of gene expression; metabolic response to exercise

(This special issue belongs to the Section Molecular Biology)

Molecular Diagnostics and Genomics of Tumors

edited by

Petra Korać

submission deadline 20 Aug 2025 | 9 articles | Viewed by 12036 | Submission Open

Keywords: tumor biology; cancer genomics; molecular diagnostics; biomarkers; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Approach to Fern Development

edited by

Helena Fernández

submission deadline 20 Aug 2025 | 5 articles | Viewed by 11788 | Submission Open

Keywords: apomixis; apogamy; asexual reproduction; fern; proteomics; genomics; plant development; evo-devo; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Pathophysiology of Lung Diseases

edited by

Theodoros Karampitsakos

and Brenda M. Juan-Guardela

submission deadline 20 Aug 2025 | 5 articles | Viewed by 11519 | Submission Open

Keywords: biomarkers; asthma; COPD; pulmonary fibrosis; post-COVID-19 interstitial lung disease; pathogenesis; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Photodynamic Therapy and Photodetection, 2nd Edition

edited by

Petras Juzenas

submission deadline 20 Aug 2025 | 9 articles | Viewed by 11065 | Submission Open

Keywords: photodynamic therapy (PDT); photodetection (PD); photosensitiser; photochemical internalization (PCI); quantum dots; nanoparticles; nanotechnology; targeted therapy; immunotherapy; vaccines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Epigenetic Genes, Biomarkers and Immunotherapy in Cancers

edited by

Urszula Oleksiewicz

and

Andrzej Mackiewicz

submission deadline 20 Aug 2025 | 5 articles | Viewed by 10772 | Submission Open

Keywords: epigenetics; epigenetic modifications; immunotherapies; immune checkpoint; DNA methylation; histone modifications; epigenetic biomarkers; epidrugs; endogenous retroviruses

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Epigenetic Modifications

edited by

Marco Miceli

, Mariella Cuomo and

Rosa Della Monica

submission deadline 20 Aug 2025 | 4 articles | Viewed by 10737 | Submission Open

Keywords: epigenetic modifications; chromatin remodeling; transcription factors; RNA modification; histones; methylation; diseases; epigenetic drugs development

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biomedical Applications of Mesenchymal Stem Cells

edited by

Giuliana Mannino

and

Debora Lo Furno

submission deadline 20 Aug 2025 | 6 articles | Viewed by 10502 | Submission Open

Keywords: mesenchymal stem cells; cell differentiation; cell therapy; regenerative medicine; tissue homeostasis; cartilage

(This special issue belongs to the Section Molecular Pharmacology)

Molecular and Cellular Advances in Endometriosis Research: 3rd Edition

edited by

Antonio Simone Laganà

submission deadline 20 Aug 2025 | 3 articles | Viewed by 10444 | Submission Open

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Computational Molecular Biology of Metabolic Pathways and Signal Transduction Pathways

edited by Ralf Herwig

submission deadline 20 Aug 2025 | 6 articles | Viewed by 10254 | Submission Open

Keywords: computational genomics; computational structural and molecular biology; molecular dynamics simulations; artificial intelligence; AI-driven drug design and development; molecular modeling; computer-aided drug design; computational proteomics; computational and theoretical chemistry

(This special issue belongs to the Section Molecular Biology)

New Insights into CKD and Age-Related Bone and Mineral Disorders

edited by

Natalia Carrillo-López

Sara Panizo

and

Cristina Alonso-Montes

submission deadline 20 Aug 2025 | 4 articles | Viewed by 10229 | Submission Open

Keywords: chronic kidney disease; CKD; CKD-MBD; mineral and bone disorder

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Therapeutic Targets in Cancers: 3rd Edition

edited by

Elena Levantini

submission deadline 20 Aug 2025 | 5 articles | Viewed by 9976 | Submission Open

Keywords: targeted therapy; precision oncology; immune modulation; cancer stem cell targeting; RNA-based therapy

(This special issue belongs to the Section Molecular Oncology)

Viral Infection and Virology Methods

edited by

Letizia Santinelli

submission deadline 20 Aug 2025 | 5 articles | Viewed by 9959 | Submission Open

Keywords: acute and chronic viral infection; molecular mechanism; new methodologies; emerging disease; innate and adaptive immunity

(This special issue belongs to the Section Molecular Microbiology)

Molecular Pharmacology in Diabetes, 2nd Edition

edited by

Rosa Fernandes

and

Flávio Reis

submission deadline 20 Aug 2025 | 3 articles | Viewed by 9865 | Submission Open

Keywords: diabetes; vascular complications; cancer; neurodegenerative disorders; key molecular players; signaling pathways; molecular biomarkers; pharmacological agents; antioxidants; anti-inflammatory agents

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms and Regulation in Chronic Kidney Diseases

edited by

Marijn Speeckaert

submission deadline 20 Aug 2025 | 4 articles | Viewed by 9711 | Submission Open

Keywords: chronic kidney disease; pathophysiology; genetic and epigenetic factors; metabolic and inflammatory pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Glycosaminoglycans in Human Diseases

edited by

Darko Kero

submission deadline 20 Aug 2025 | 4 articles | Viewed by 9609 | Submission Open

Keywords: glycosaminoglycans; inflammation; infectious disease; cancer

(This special issue belongs to the Section Biochemistry)

Molecular Application of Mass Spectrometry and Chromatography in Biomedicine

edited by

Giovanni Ventura

submission deadline 20 Aug 2025 | 6 articles | Viewed by 9303 | Submission Open

Keywords: mass spectrometry; chromatography; LC-MS; GC-MS; biomarker discovery; pharmaceuticals; metabolimics; proteomics; lipidomics

(This special issue belongs to the Section Molecular Biophysics)

Antioxidant, Anti-Inflammatory, and Antimicrobial Activities of Phytochemicals: Bridging Traditional Knowledge and Molecular Insights

edited by

Ramona Suharoschi

Oana Lelia Pop

and

Adriana Fodor

submission deadline 20 Aug 2025 | 2 articles | Viewed by 9298 | Submission Open

Keywords: phytochemicals; antioxidant activities; anti-inflammatory properties; antimicrobial effects; molecular mechanisms; clinical applications; traditional medicine; bioavailability; safety and toxicology and regulatory aspects of phytochemicals; pharmacological interaction

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 1551-1600 on page 32 of 69.

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