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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights in Bacterial Infection Research: From Mechanisms to Therapies

edited by Marcin Równicki and

Tania Silva

submission deadline 20 Jul 2025 | Viewed by 943 | Submission Open

Keywords: bacteria; infection; antibiotic resistant; bacterial persisters; antimicrobial therapies; host-pathogen interactions

(This special issue belongs to the Section Molecular Microbiology)

Interplay of Metabolism and Inflammation in Gastrointestinal Disease

edited by Marios Papadakis and

Stavros P. Papadakos

submission deadline 20 Jul 2025 | Viewed by 939 | Submission Open

Keywords: gastrointestinal diseases; inflammation; metabolic dysregulation; metabolic processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Genetic Variants of Parkinson’s Disease

edited by Michael Schlossmacher and

Ari Zimran

submission deadline 20 Jul 2025 | 1 articles | Viewed by 932 | Submission Open

Keywords: DNA; PD prevention; genetic variants of Parkinson's disease

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in Nanomedicines Against Bacterial Infections

edited by

Stephanie Andrade

, Nuno Guimarães,

Maria João Ramalho

and

Joana A. Loureiro

submission deadline 20 Jul 2025 | Viewed by 923 | Submission Open

Keywords: nanotechnology; nanoparticle; nanocarriers; nanoantibiotic; drug delivery system; targeted delivery; theranostic; infectious diseases; antibacterial agent; antimicrobial resistance; biomedical application

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Research on Tumor Suppressor Proteins

edited by Jie Liu

submission deadline 20 Jul 2025 | 1 articles | Viewed by 851 | Submission Open

Keywords: DNA repair; genome stability; tumor suppressor; BRCA1; BRCA2; PALB2; RAD51C

(This special issue belongs to the Section Molecular Oncology)

Molecular Research in Redox Balance in Pathological and Physiological Conditions

edited by

Pawel Sutkowy

submission deadline 20 Jul 2025 | 1 articles | Viewed by 848 | Submission Open

Keywords: oxidative stress; nitrosative stress; antioxidative stress; redox signaling; inflammation; antioxidants; reactive oxygen species; reactive nitrogen species; pathological states; physiological condition

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Neurologic and Neurodegenerative Disorders

edited by

Ioana-Miruna Balmus

and

Ioannis Mavroudis

submission deadline 20 Jul 2025 | 1 articles | Viewed by 823 | Submission Open

Keywords: traumatic brain injury; chronic traumatic encephalopathy; Alzheimer’ s disease; motor neuron disease; amyotrophic lateral sclerosis; neurosignalling; neurodegeneration; brain– gut axis impairment; oxidative stress; chronic inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neurodegeneration and Neuroinflammatory Processes in Age-Related Diseases

edited by

Barbara Mroczko

submission deadline 20 Jul 2025 | 2 articles | Viewed by 800 | Submission Open

Keywords: age-related diseases; neurodegenerative diseases; neurodegeneration; neuroinflammation; aging

(This special issue belongs to the Section Molecular Neurobiology)

The 50th Anniversary of the Discovery of Reciprocal Translocation between Chromosome 9 and 22: The Impact on Molecular and Genomic Knowledge on Cancer

edited by

Ana Cristina Gonçalves

Raquel Alves

and

Ana Bela Sarmento Ribeiro

submission deadline 20 Jul 2025 | Viewed by 751 | Submission Open

Keywords: cancer genomics; cancer biomarkers; cancer pathogenesis; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Molecular Research of Gut Microbiota in Human Health and Diseases

edited by

Juan Francisco Martínez-Blanch

submission deadline 20 Jul 2025 | Viewed by 744 | Submission Open

Keywords: gut microbiota; gut metabolites; gastroenterology; microbiology; inflammation; human diseases

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insights into the Obstetrics and Gynecology

edited by

Gaspare Cucinella

submission deadline 20 Jul 2025 | Viewed by 738 | Submission Open

Keywords: ginecology; pelvic disorders; endometrial; cervical and ovarian cancers; covid and pregnancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Review Papers in Molecular Genetics and Genomics 2024

edited by

Apostolos Zaravinos

submission deadline 20 Jul 2025 | Viewed by 692 | Submission Open

Keywords: gene regulation; chromatin; epigenetics; genomes; cancer genetics and epigenetics; functional genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Cell Envelope Biogenesis and, Molecular Strategies to Maintain Cellular Homeostasis in Bacteria

edited by

Satish Raina

and

Gracjana Klein

submission deadline 20 Jul 2025 | 1 articles | Viewed by 681 | Submission Open

Keywords: LpxC and the regulation of LPS; periplasmic protein folding; disulfide bond formation; BAM proteins and assembly of outer membrane proteins; periplasmic protease DegP (HtrA); lipopolysaccharide assembly; LPS modifications and diversity; LPS and phospholipid trafficking; bacterial virulence factors; antibiotic resistance; extracytoplasmic function sigma factors; regulatory RNAs; two-component systems; lipid A and its modification

(This special issue belongs to the Section Molecular Microbiology)

Synthesis and Characterization of Nanocarriers and Hydrogels for Multiple Biomedical Applications

edited by

Tilahun Ayane Debele

submission deadline 20 Jul 2025 | Viewed by 669 | Submission Open

Keywords: nanocarrier synthesis; nanocarrier characterization; stimulus-sensitive nanocarriers; hydrogels; drug delivery systems; biomedical applications; nanotechnology in medicine; targeted drug delivery; controlled release; theranostic; nanomedicine; pH-sensitive nanocarriers; temperature-sensitive hydrogels; polymer-based nanocarriers; nanoparticle-hydrogel composites

(This special issue belongs to the Section Molecular Nanoscience)

Modulating the Function of the Immune System by Thyrotropin and Thyroid Hormones

edited by Graciela Alicia Cremaschi and Claudia Gabriela Pellizas

submission deadline 20 Jul 2025 | Viewed by 635 | Submission Open

Keywords: thyrotropin (TSH); thyroid hormones (THs); immune modulation; immunology; immune; autoimmune; immunoendocrinology; hypothalamic-pituitary-thyroid axis; antitumor immune response

(This special issue belongs to the Section Molecular Immunology)

Natural Compounds: Structural Diversity, Modifications, and Biological Activities

edited by Tomasz Pospieszny

submission deadline 20 Jul 2025 | 1 articles | Viewed by 626 | Submission Open

Keywords: bile acids; molecular research; biological activity; natural products; steroids

(This special issue belongs to the Section Bioactives and Nutraceuticals)

KRAS-Mutant Cancers: From Basic Biology to Clinical Translation

edited by

Mirela Sedic

Sérgia Velho

and Luka Bočkor

submission deadline 20 Jul 2025 | Viewed by 624 | Submission Open

Keywords: KRAS mutations; KRAS signalling; cancer; KRAS inhibitors; drug resistance; tumour microenvironment; cellular metabolism

(This special issue belongs to the Section Molecular Oncology)

Stroke: Novel Molecular Mechanisms and Therapeutic Approaches

edited by Kang-Ho Choi

submission deadline 20 Jul 2025 | Viewed by 611 | Submission Open

Keywords: stroke; cerebrovascular disease; mechanisms; treatment; diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights and Research on Nutrition and Obesity

edited by

Giovanna Bermano

submission deadline 20 Jul 2025 | 1 articles | Viewed by 576 | Submission Open

Keywords: nutrition; obesity; malnutrition; overnutrition; molecular and cellular mechanisms; nutrient– gene interactions; metabolic disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

GABA Signaling in Health and Disease in the Nervous System, 2nd Edition

edited by

Alexandre Hiroaki Kihara

submission deadline 20 Jul 2025 | Viewed by 569 | Submission Open

Keywords: gamma-aminobutyric acid; neurodevelopment; neuronal differentiation; neuronal disorders; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Iron and Sulfur in Plants, 4th Edition

edited by

Stefania Astolfi

and

Silvia Celletti

submission deadline 20 Jul 2025 | Viewed by 566 | Submission Open

Keywords: biofortification; Fe– S clusters; iron; iron deficiency; metabolites; methionine; nutrient interaction; root exudates; strategy I; strategy ii; sulfur; sulfur deficiency

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in the Genetic Research on Psychiatric Disorders

edited by Lawrence Shih-Hsin Wu

submission deadline 20 Jul 2025 | Viewed by 563 | Submission Open

Keywords: genetics; bipolar disorder; schizophrenia; major depressive disorder; autism; substance abuse; genomics

(This special issue belongs to the Section Molecular Neurobiology)

Colorectal Cancer: Molecular Mechanism and Treatment Strategies

edited by

Pina Ziranu

submission deadline 20 Jul 2025 | Viewed by 522 | Submission Open

Keywords: colorectal cancer; personalized treatment; treatment strategies; cancer biology

(This special issue belongs to the Section Molecular Oncology)

Molecular and Cellular Mechanisms of Genotoxicity

edited by

Bernd Kaina

submission deadline 20 Jul 2025 | Viewed by 513 | Submission Open

Keywords: DNA damage; gene instab; genetic instab; DNA methyl; genotoxic; gene mutation; DNA repair; genotoxicity; toxicogenetic; toxicogenomic

(This special issue belongs to the Section Molecular Toxicology)

Rational Design and Synthesis of Bioactive Molecules, 2nd Edition

edited by

Irena Kostova

submission deadline 20 Jul 2025 | Viewed by 510 | Submission Open

Keywords: synthesis; structure; bonding; reactivity; chemical properties; physical properties; pharmacological activity; structure– activity relationship; applications

(This special issue belongs to the Section Molecular Biology)

Molecular and Cellular Mechanisms of Skin Diseases (Second Edition)

edited by

Elisabetta Palazzo

submission deadline 20 Jul 2025 | 1 articles | Viewed by 506 | Submission Open

Keywords: hyperproliferative skin diseases; psoriasis; keratinocyte carcinoma; actinic keratosis; atopic dermatitis; skin inflammation; inflammation-associated skin diseases; epidermal differentiation; epidermal cell metabolism; 3D models; in vivo models

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Hereditary Spherocytosis

edited by

Susana Rocha

and

Alice Santos-Silva

submission deadline 20 Jul 2025 | Viewed by 501 | Submission Open

Keywords: hereditary spherocytosis; erythrocyte membrane molecular defects; next-generation sequencing; molecular diagnosis; molecular mechanisms of disease

(This special issue belongs to the Section Molecular Genetics and Genomics)

Vitamin D Signaling in Human Health and Diseases

edited by

Daniela Rovito

submission deadline 20 Jul 2025 | Viewed by 494 | Submission Open

Keywords: vitamin D receptor; vitamin D; prevention; therapeutic potential; mineral homeostasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Therapeutic Strategies to Overcome Drug Resistance in Cancer

edited by

Inamul Haque

submission deadline 20 Jul 2025 | Viewed by 482 | Submission Open

Keywords: drug resistance; cancer therapy; targeted therapy; nanotechnology; tumor microenvironment; signaling pathway; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Mechanistic Studies of Mitosis

edited by Eleni Petsalaki

submission deadline 20 Jul 2025 | Viewed by 479 | Submission Open

Keywords: mitosis; cancer; cell biology; spindle checkpoint; abscission; abscission checkpoint; cytokinesis

(This special issue belongs to the Section Biochemistry)

Advancements in Genomic Technologies for Molecular Safety Assessment

edited by

Eric Blomme

submission deadline 20 Jul 2025 | Viewed by 478 | Submission Open

Keywords: gene expression; safety assessment; genomic technologies; genomic tools; molecular toxicology; toxicity; predictive safety assessments; proteomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Superoxide

edited by

Francesco Caruso

and

Miriam Rossi

submission deadline 20 Jul 2025 | Viewed by 472 | Submission Open

Keywords: superoxide; SOD; antioxidants; superoxide radical; natural product

(This special issue belongs to the Section Biochemistry)

Molecular Insight into Skin Infection and Inflammation

edited by

Danuta Nowicka

submission deadline 20 Jul 2025 | Viewed by 465 | Submission Open

Keywords: skin infection; skin inflammation; inflammatory skin diseases; atopic dermatitis; skin microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Omics-Driven Unveiling of the Structure and Function of Nanoparticles

edited by

Elva Morretta

submission deadline 20 Jul 2025 | Viewed by 462 | Submission Open

Keywords: nanoparticles; nanotechnology; drug delivery; protein corona; proteomics; nano-proteomics; matabolomics; lipidomics

(This special issue belongs to the Section Molecular Biophysics)

Molecular Research in Myocarditis

edited by Cristina Vicenzetto

submission deadline 20 Jul 2025 | 1 articles | Viewed by 461 | Submission Open

Keywords: myocarditis; autoimmunity; viral myocarditis; molecular mechanisms; genetic background; therapeutic targets

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Molecular Pathology, Drug Resistance and Diagnostics of Human Fungal Diseases

edited by

Chi-Ching Tsang

submission deadline 20 Jul 2025 | Viewed by 460 | Submission Open

Keywords: host-fungal interaction; pathogenesis; virulence; antifungal immunity; antifungal resistance; molecular diagnosis

(This special issue belongs to the Section Molecular Microbiology)

Molecular Metabolism in Plant Chemistry

edited by

Diamanto Lazari

submission deadline 20 Jul 2025 | Viewed by 446 | Submission Open

Keywords: phytochemistry; plant secondary metabolism; biosynthesis of secondary metabolites; plant and pathogens; stress tolerance and resistance; plant cell cultures; plant biotechnology; bioactive natural products

(This special issue belongs to the Section Biochemistry)

Optical Molecular Systems: From Design to Applications

edited by

Amador Menéndez-Velázquez

submission deadline 20 Jul 2025 | Viewed by 445 | Submission Open

Keywords: luminescent materials; spectral conversion; smart optical materials; human-centric lighting; healthcare diagnostics; imaging; and therapeutics; advanced optical sensors

(This special issue belongs to the Section Materials Science)

Molecular Applications of Spectroscopy in Drug Structure and Activity Analysis

edited by

Malvina Orkoula

submission deadline 20 Jul 2025 | Viewed by 445 | Submission Open

Keywords: spectroscopic techniques; Raman microscopy and imaging; IR/FT-IR/ATR; UV/Vis; XRD; polymorphic forms; material purity; pharmaceutical finished products; biosimilars; stability of APIs and excipients; interaction between APIs and excipients; counterfeit identification; reverse engineering in pharmacy; at-line; in-line

(This special issue belongs to the Section Molecular Biophysics)

Neurogenetics: Applications of Precision Medicine and Gene Therapy for Rare Neurogenetic Disorders

edited by

Paschalis Theotokis

submission deadline 20 Jul 2025 | Viewed by 443 | Submission Open

Keywords: precision medicine; gene therapy; neurogenetics; rare monogenic diseases; inherited nervous system disorders; mitochondrial diseases (e.g.; LHON; MELAS); lysosomal storage disorders (e.g.; Tay– Sachs; Gaucher); hereditary neuropathies (e.g.; CMT; hATTR); motor neuron diseases (e.g.; SMA; ALS); spinocerebellar ataxias (e.g.; SCA); biomarkers in neurology

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Cellular Mechanisms in Learning and Memory

edited by

Giovanna Traina

submission deadline 20 Jul 2025 | Viewed by 438 | Submission Open

Keywords: learning; memory; animal models; conditioning; molecular mechanisms; genetic mechanisms; epigenetic mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Studies of Age-Related Diseases: Immunosenescence and Inflammaging

edited by

Lia Ginaldi

submission deadline 20 Jul 2025 | Viewed by 437 | Submission Open

Keywords: aging; age-related; immunosenescence; immune system; inflammaging

(This special issue belongs to the Section Molecular Immunology)

Myelination in the Nervous Systems: From Molecular Pathways to Therapeutic Strategies

edited by Yanming Wang

submission deadline 20 Jul 2025 | Viewed by 408 | Submission Open

Keywords: myelination; the central nervsou system; neurodegenerative discorders; multiple sclerosis; leukodystrophies; myelin repair and regeneration

(This special issue belongs to the Section Molecular Biology)

Role of the Epithelial Mesenchymal Transition in Cancer Development and Invasiveness

edited by

Elisabetta Aldieri

submission deadline 20 Jul 2025 | Viewed by 406 | Submission Open

Keywords: epithelial mesenchymal transition; EMT; cancer; epithelial protein; mesenchymal phenotype; therapeutic approach

(This special issue belongs to the Section Molecular Oncology)

Molecular Linkages Between Obesity, Diabetes and Cancer

edited by Pilar F. Valerón

submission deadline 20 Jul 2025 | Viewed by 401 | Submission Open

Keywords: obesity; GLUT4; PPARg; lipid transporters (CD36 and AQP7); cancer progression; metastasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chemoinformatics and Bioinformatics Tools in Structure-Activity Modelling in Molecular Sciences: 3rd Edition

edited by

Bono Lučić

submission deadline 20 Jul 2025 | Viewed by 387 | Submission Open

Keywords: chemoinformatics tools and models; bioinformatics tools and models; structure– activity modeling; structure– property modeling; QSAR; QSPR; drug/structure identification in bioprospecting research; molecular docking; molecular interactions; protein– protein interactions; development of algorithms; databases and web servers; data mining in chemoinformatics and bioinformatics; structure representation and optimization; molecular descriptors; modeling of health and environmentally relevant endpoints (activities; properties); toxicity modeling and prediction; carcinogenicity modeling and prediction; computational methods in molecular sciences; model validation approaches; multivariate modeling; predictive modeling; descriptive modeling; continuous data modeling; classification data modeling; machine learning in molecular sciences; deep learning in molecular sciences; structure visualization tools

(This special issue belongs to the Section Molecular Informatics)

The Molecular Mechanisms and Pathogenesis of Food Allergy and New Technologies

edited by

Mónica Carrera

submission deadline 20 Jul 2025 | Viewed by 383 | Submission Open

Keywords: food allergy; omics; genomics; proteomics; transcriptomics; metabolomics; systems biology; micro/nanoabrication

(This special issue belongs to the Section Molecular Immunology)

From Bench to Bedside: A Triad of Innovation in Gastric Cancer Treatment—Immunotherapies, Gene Therapy and Surgery Unite

edited by

Gregory Christodoulidis

submission deadline 20 Jul 2025 | Viewed by 382 | Submission Open

Keywords: immunotherapy; gene therapy; advanced surgery

(This special issue belongs to the Section Molecular Oncology)

Chronic Lymphocytic Leukemia: Molecular Pathologies and Therapeutic Strategies

edited by Tang Her Jaing

submission deadline 20 Jul 2025 | Viewed by 378 | Submission Open

Keywords: chronic lymphocytic leukemia; genomic landscapes; precision medicine; clinical trials; biomarker

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Cancer Stem Cell Research: 2nd Edition

edited by

Tomoyasu Sugiyama

submission deadline 20 Jul 2025 | Viewed by 378 | Submission Open

Keywords: cancer stem cell; biomarker; signaling; cancer-associated fibroblast; artificial intelligence; cell therapy; antibody therapy; cell therapy; gene expression

(This special issue belongs to the Section Molecular Oncology)

Displaying special issue 1251-1300 on page 26 of 69.

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