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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Glycobiology: The New Discoveries, Approaches, and Technical Developments: 2nd Edition

edited by Sanja Dabelić

submission deadline 20 May 2026 | 2 articles | Viewed by 1416 | Submission Open

Keywords: glycans; lectins; glycoconjugates; glycosylation; genetic disorders of glycosylation; glycomics and glycoproteomics

(This special issue belongs to the Section Macromolecules)

Synthesis Manufacturing and Biomedical Applications of Nanofibers Scaffold

edited by

Marco Antonio Álvarez Pérez

and

Vincenzo Guarino

submission deadline 20 May 2026 | 1 articles | Viewed by 1288 | Submission Open

Keywords: scaffold manufacturing; nanofibers; 3D platforms; biohybrid scaffolds; biomolecules; functionalization; biomaterials

(This special issue belongs to the Section Molecular Nanoscience)

New Research on Bioactive Natural Products: 2nd Edition

edited by

Alexandros Tsoupras

submission deadline 20 May 2026 | 1 articles | Viewed by 1273 | Submission Open

Keywords: chronic disorders; bioactives; natural sources; sustainable sources; biomolecular; structure– activity relationship; synergism; health promoting; bio-functional; products; supplements; nutraceuticals; drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances and Mechanisms in Breast Cancer—2nd Edition

edited by

Ioannis Boutas

submission deadline 20 May 2026 | 1 articles | Viewed by 1242 | Submission Open

Keywords: breast cancer; genes and molecular pathways; targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pancreatic Diseases: Molecular Pathology and Therapeutics

edited by

Maria Ines Vaccaro

submission deadline 20 May 2026 | 1 articles | Viewed by 1231 | Submission Open

Keywords: pancreatic cancer; acute pancreatitis; chronic pancreatitis; diabetes; inflammation; molecular markers; therapeutic strategies; genetic predispositions; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advancements in Regenerative Medicine Research

edited by

Rosa V. Ventrella

submission deadline 20 May 2026 | 1 articles | Viewed by 1216 | Submission Open

Keywords: regenerative medicine; tissue repair; wound healing; stem cells; cell differentiation; cell signalling; gene regulation; mechanotransduction; precision medicine

(This special issue belongs to the Section Molecular Biology)

Multifunctional Magnetic Nanoparticles: Synthesis, Properties, and Biomedical Applications

edited by

Krishtappa Manjunatha

submission deadline 20 May 2026 | Viewed by 1197 | Submission Open

Keywords: magnetic nanoparticles; molecular functionalization; magnetocaloric materials; drug delivery systems; molecular imaging; magnetic memory; nanocomposites; nanophosphors; environmental remediation; energy storage materials; magnetic biosensing; biofunctional interfaces

(This special issue belongs to the Section Molecular Nanoscience)

Advanced Molecular Research on Pregnancy Complication Mechanisms

edited by

Aleksandra Stefanović

submission deadline 20 May 2026 | 1 articles | Viewed by 1144 | Submission Open

Keywords: hypertensive pregnancy disorders; gestational diabetes; intrauterine growth restriction; maternal metabolism in pregnancy complications; genetic and epigenetic mechanisms in pregnancy complications; immunology in pregnancy complications

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Gastrointestinal Inflammation: From Pathogenesis to Molecular Diagnosis and Treatment

edited by

Nikolett Bódi

submission deadline 20 May 2026 | 1 articles | Viewed by 1078 | Submission Open

Keywords: gastrointestinal tract; inflammation; gastroenteritis; infection; microbiome; mucosal epithelium; immune cells; enteric nervous system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Electrochemical Nanomaterials for Energy and Catalysis

edited by

Sankar Sekar

submission deadline 20 May 2026 | 1 articles | Viewed by 1053 | Submission Open

Keywords: advanced micro- and nanomaterials for electrochemical applications; electrochemical energy storage; electrocatalysis; photoelectrochemical water splitting; electrochemical sensors; supercapacitor; batteries; nanocomposites and functionalized materials; energy storage and conversion application; natural resources-based materials

(This special issue belongs to the Section Molecular Nanoscience)

Analysis on Effector and Regulatory Molecules in Renal Diseases

edited by

Takashi Oda

submission deadline 20 May 2026 | 1 articles | Viewed by 1048 | Submission Open

Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural and Synthetic Modified Nucleic Acids: Their Properties, Functions and Applications

edited by

Malgorzata Sierant

submission deadline 20 May 2026 | 2 articles | Viewed by 1031 | Submission Open

Keywords: DNA; RNA; nucleic acid analogues; modified nucleosides; modified nucleosides identification techniques; nucleoside modifying enzymes; gene therapy; therapeutic nucleic acids; biomedical applications; drug delivery

(This special issue belongs to the Section Molecular Biology)

Exploring Rare Diseases: Genetic, Genomic and Metabolomic Advances: 2nd Edition

edited by

Judit Bene

and

Kinga Hadzsiev

submission deadline 20 May 2026 | 1 articles | Viewed by 998 | Submission Open

Keywords: rare diseases; genotype– phenotype analyses; NGS; mass spectrometry; biomarker discovery; molecular targeted therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in the Structure, Biological Activity and Structure–Activity Relationship of Polysaccharides

edited by

Natalia Nowacka-Jechalke

and

Marta Kinga Lemieszek

submission deadline 20 May 2026 | 2 articles | Viewed by 997 | Submission Open

Keywords: natural polysaccharides; phytochemicals; nutraceuticals; structure– activity relationship; anticancer potential; immunomodulation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Eukaryotic DNA Replication—from Bench to Bedside

edited by Heinz-Peter Nasheuer

submission deadline 20 May 2026 | 1 articles | Viewed by 965 | Submission Open

Keywords: genome stability; cell cycle; DNA replication; chromatin replication; replication origins— selection; licensing and firing; replication forks— smoothly progressing and under stress; role of DNA replication in cancer and other human diseases; disease treatment opportunities

(This special issue belongs to the Section Molecular Genetics and Genomics)

Surfactants: Design, Synthesis and Application

edited by

Urszula Bazylinska

submission deadline 20 May 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: surfactants; adsorption phenomena; critical micellar concentration (CMC); hydrophilic– lipophilic balance (HLB); critical packing parameter (CPP); emulsion formulations; vesicular and non-vesicular origin nanocarriers; drug delivery; theranostics

(This special issue belongs to the Section Materials Science)

Advances in the Translational Preclinical Research

edited by

Mariano Gabri

submission deadline 20 May 2026 | 1 articles | Viewed by 887 | Submission Open

Keywords: translational preclinical research; drug discovery; cancer therapies; in vitro and in vivo experiments; biological mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Extracellular Vesicles in Disease and Therapeutic Applications

edited by Sunyoung Park

submission deadline 20 May 2026 | 1 articles | Viewed by 840 | Submission Open

Keywords: extracellular vesicles (EVs); disease biomarkers; EV-based therapeutics; cancer diagnosis; drug delivery; immune modulation; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Synthesis and Application of Natural and Inspired-Natural Products

edited by Mauro de Nisco

submission deadline 20 May 2026 | 1 articles | Viewed by 789 | Submission Open

Keywords: natural products; natural substances; derivative; synthesis; application

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Emerging Roles of the Gut-Brain Axis (GBA) in Health and Disease

edited by Vinata Vedam-Mai

submission deadline 20 May 2026 | 1 articles | Viewed by 766 | Submission Open

Keywords: gut– brain axis; gut microbiota; brain function; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unraveling the Molecular Landscape of Primary Brain Tumors

edited by

Giuseppe Lombardi

, Francesco Pasqualetti and Tamara Ius

submission deadline 20 May 2026 | Viewed by 742 | Submission Open

Keywords: primary brain tumors; molecular oncology; glioma; glioblastoma; biomarkers; targeted therapy; epigenetics; tumor microenvironment; genomic profiling; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Survival of the Fittest: Physiological Adaptations of Insects in Hostile Environments

edited by

Amit Roy

and

Amrita Chakraborty

submission deadline 20 May 2026 | Viewed by 678 | Submission Open

Keywords: insect adaptation; temperature tolerance; insect physiology; detoxification; symbiosis and stress tolerance mechanisms

(This special issue belongs to the Section Molecular Biology)

New Molecular Insights into Antibacterial Material

edited by Rahela Carpa

submission deadline 20 May 2026 | 1 articles | Viewed by 656 | Submission Open

Keywords: antimicrobial resistance; nanoparticles; biopolymers; antimicrobial peptides; antimicrobial materials

(This special issue belongs to the Section Materials Science)

Current Advance in Infectious and Inflammatory Diseases

edited by

Justyna Agier

and

Paulina Żelechowska

submission deadline 20 May 2026 | 1 articles | Viewed by 652 | Submission Open

Keywords: inflammatory diseases; infectious diseases; host– pathogen interactions; antimicrobial resistance; immune modulation; cytokine signaling

(This special issue belongs to the Section Molecular Microbiology)

Computational Approaches in Biomedicine: Innovations and Insights

edited by

Carlos Leon

submission deadline 20 May 2026 | Viewed by 602 | Submission Open

Keywords: computational biomedicine; artificial intelligence; machine learning; omic technologies; system biology; medical imaging; structural biology; drug discovery

(This special issue belongs to the Section Molecular Informatics)

Lipoproteins—Opportunities for the Development of Nanotherapeutics in Chronic Disease

edited by

Thomas Grewal

submission deadline 20 May 2026 | Viewed by 597 | Submission Open

Keywords: lipoproteins; LDL; HDL; nanotherapeutics; chronic disease; targeted therapy; drug delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Repair Mechanisms of Stem Cells

edited by

Ana Flores

and

Jose Joaquin Merino

submission deadline 20 May 2026 | Viewed by 596 | Submission Open

Keywords: stem cell biology; stem cells; stem cell therapy; tissue regeneration

(This special issue belongs to the Section Biochemistry)

Chessboard: How Plants and Insects Outsmart Each Other

edited by

Mateusz Labudda

submission deadline 20 May 2026 | 1 articles | Viewed by 592 | Submission Open

Keywords: acarology; biotic stress; entomology nitric oxide; oxidative stress; phytopathology; reactive nitrogen species; reactive oxygen species

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Transcription Factors in Antioxidant Pathways

edited by

Eleonora Stanca

submission deadline 20 May 2026 | 1 articles | Viewed by 575 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Current Research in Membrane Transporters, Channels, and Receptors

edited by Ivana Vrhovac Madunic

submission deadline 20 May 2026 | 1 articles | Viewed by 566 | Submission Open

Keywords: membrane transporters; cell membrane; transmembrane proteins; glucose transport; ion channels; cellular receptors; signal tranduction; pathophysiology; diabetes; aging

(This special issue belongs to the Section Molecular Biology)

New Biomarkers in Pancreatic Diseases

edited by

Laura Gaman

and

Mihaela Badea

submission deadline 20 May 2026 | Viewed by 530 | Submission Open

Keywords: pancreatic disease; pancreatic cancer; pancreatitis; biomarker; RNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cell Death in Human Diseases: Mechanisms, Biomarkers and Therapeutic Opportunities

edited by

Decha Pinkaew

submission deadline 20 May 2026 | Viewed by 514 | Submission Open

Keywords: cell death; apoptosis; necroptosis; ferroptosis; pyroptosis; human disease; biomarkers

(This special issue belongs to the Section Molecular Biology)

X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes

edited by Yoram Chaiter and

Yossy Machluf

submission deadline 20 May 2026 | Viewed by 505 | Submission Open

Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Heart Failure: From Pathogenesis to Innovative Treatments

edited by Volker Adams and

Ephraim Bernhard Winzer

submission deadline 20 May 2026 | 1 articles | Viewed by 502 | Submission Open

Keywords: heart failure; HFrEF; HFpEF; comorbidities; pathophysiology; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Ocular Inflammation and Infection

edited by

Christine Fardeau

submission deadline 20 May 2026 | 1 articles | Viewed by 492 | Submission Open

Keywords: ocular infections; uveitis; choroiditis; masquerade syndrome; pseudo-uveitis; intraocular lymphoma; retinal dystrophy; ocular inflammation; neuroinflammation; immunotherapy-induced uveitis; autoimmune eye diseases; sarcoidosis; OCT; indocyanine green angiography

(This special issue belongs to the Section Molecular Immunology)

Advances in Endoplasmic Reticulum Stress and Apoptosis—Second Edition

edited by

Orsolya Kapuy

and

Beáta Lizák

submission deadline 20 May 2026 | 2 articles | Viewed by 479 | Submission Open

Keywords: ER stress; apoptosis initiated by ER stress; cellular survival; redox homeostasis of ER; autophagy initiated by ER stress; cell death pathways initiated by ER stress

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms of Skeletal Muscle Adaptation

edited by

Michele Salanova

submission deadline 20 May 2026 | 1 articles | Viewed by 471 | Submission Open

Keywords: skeletal muscle; adaptive responses; muscle physiology; genomics; transcriptomics; proteomics; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Biological Breeding and Molecular Biology of Tropical Crops

edited by Yongzan Wei

submission deadline 20 May 2026 | 1 articles | Viewed by 441 | Submission Open

Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology

edited by Richard H. W. Funk

submission deadline 20 May 2026 | Viewed by 428 | Submission Open

Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors

(This special issue belongs to the Section Molecular Biophysics)

Pathogenesis and Treatment of Prostate Cancer

edited by

Vincenzo Fiorentino

submission deadline 20 May 2026 | Viewed by 367 | Submission Open

Keywords: prostate cancer; pathogenesis; genetic mutations; target therapy; surgery; radiation therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Understanding Respiratory Virus–Host Interactions

edited by Kun Li

submission deadline 20 May 2026 | Viewed by 348 | Submission Open

Keywords: respiratory viruses; virus– host interactions; molecular mechanisms; viral replication; host– immune response; molecular pathogenesis; molecular signaling; antiviral strategies

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Neurofibromatosis Type 1: From Molecular Insights to Novel Therapies

edited by László Szabó and

Márta Medvecz

submission deadline 20 May 2026 | Viewed by 343 | Submission Open

Keywords: neurofibromatosis type 1; genotype– phenotype analyses; molecular pathogenesis; next-generation sequencing (NGS); molecular targeted therapy; MEK inhibitors; imaging studies

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Research in Nanophotonics and Biophotonics

edited by

Prabhakar Pradhan

submission deadline 20 May 2026 | Viewed by 339 | Submission Open

Keywords: biophotonics; spectroscopy; light scattering; Raman/FTIR; cancer; Alzheimer's and Parkinson’ s diseases; nanophotonics; plasmonics; nano-biophotonics

(This special issue belongs to the Section Molecular Nanoscience)

New Advances in Reproductive Immunology and Pathology

edited by Silvia Giugliano

submission deadline 20 May 2026 | Viewed by 319 | Submission Open

Keywords: maternal– fetal immune tolerance; reproductive immunopathology; cytokine signaling in pregnancy; immune-related infertility; metabolome-immune crosstalk; microbiome influence on fertility

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Antimicrobial Agents: Mechanisms and Applications

edited by

Aleksandra Maria Kocot

submission deadline 20 May 2026 | Viewed by 317 | Submission Open

Keywords: antimicrobial compounds; antibacterial activity; antibiotic resistance; pathogen-tailored therapeutic targeting; novel antimicrobials; molecular aspects of the mechanisms of action of antibacterial substances; effectiveness of antibacterial substances

(This special issue belongs to the Section Biochemistry)

Advanced Research on Comparative Reproductive Physiology

edited by

Heriberto Rodriguez-Martinez

and

Manuel Álvarez-Rodríguez

submission deadline 20 May 2026 | Viewed by 306 | Submission Open

Keywords: andrology; sperm; oocyte; gamete interactions; reproductive morphology; reproductive endocrinology; omics; epigenetics; pregnancy; all animal species

(This special issue belongs to the Section Molecular Biology)

Unraveling Neuroimmune Disorders: From Pathogenic Pathways to Biomarker-Driven Precision Medicine

edited by

Mariapaola Marino

submission deadline 20 May 2026 | Viewed by 280 | Submission Open

Keywords: innate immunity; adaptive immunity; inflammation; autoantibodies; peptides; cytokines; receptors; leukocytes; extracellular vesicles; signal transduction; apoptosis

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances in Primary Colorectal Cancer and Liver Metastases

edited by Alexandros E. Giakoustidis

submission deadline 20 May 2026 | Viewed by 278 | Submission Open

Keywords: colorectal cancer; metastasis; treatment; management; screening; genetic alterations; epigenetic alterations; genomics; epigenomics; methylation; liver-directed therapy; radiation; immunotherapy; peritoneal carcinomatosis; monotherapy; chemotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms Linked to Exercise

edited by Igor Zubrzycki

submission deadline 20 May 2026 | Viewed by 267 | Submission Open

Keywords: molecular mechanisms; exercise adaptations; translational health

(This special issue belongs to the Section Molecular Biology)

Targeted Protein Degradation: From Molecular Mechanisms to Therapeutic Applications

edited by

Asim Debnath

submission deadline 20 May 2026 | Viewed by 266 | Submission Open

Keywords: targeted protein degradation; ubiquitin– proteasome system; PROTAC; drug design; medicinal chemistry

(This special issue belongs to the Section Molecular Pharmacology)

Displaying special issue 3201-3250 on page 65 of 69.

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