New Advances in Reproductive Immunology and Pathology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 14
Special Issue Editor
2. IRCCS Humanitas Research Hospital, Rozzano, 20089 Milan, Italy
Interests: immunology with a focus on inflammatory cytokines in immune-mediated and infectious diseases, integrating microbiology, metabolism, and nutrition to advance maternal-fetal health and reproductive medicine; multiomic and translational approaches to uncover molecular mechanisms and identify potential therapeutic targets
Special Issue Information
Dear Colleagues,
Reproductive immunology is a rapidly evolving field that explores the complex interactions between the immune system and reproductive processes. From conception to implantation, placental development, and parturition, immune mechanisms play a crucial role in ensuring successful reproduction. However, disruptions in immunological tolerance and regulation can lead to a spectrum of reproductive pathologies, including infertility, recurrent pregnancy loss, preeclampsia, endometriosis, and autoimmune-mediated pregnancy complications.
This Special Issue of the International Journal of Molecular Sciences aims to provide a comprehensive overview of current advances in reproductive immunology and their implications for understanding and managing reproductive disorders. We welcome the submission of original research articles, reviews, and short communications that explore immune cell populations in the reproductive tract, cytokine networks, maternal–fetal tolerance, immunogenetics, and the impact of systemic inflammation or infections on fertility and pregnancy outcomes. We also welcome the submission of articles that employ molecular, cellular, clinical, or translational approaches.
We will particularly focus on studies that integrate immunological insights with reproductive pathology to identify potential diagnostic markers or therapeutic targets. By collating interdisciplinary perspectives, this Special Issue seeks to enhance our understanding of reproductive immunopathology and foster innovations that could improve reproductive health and pregnancy care.
Dr. Silvia Giugliano
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- maternal–fetal immune tolerance
- reproductive immunopathology
- cytokine signaling in pregnancy
- immune-related infertility
- metabolome-immune crosstalk
- microbiome influence on fertility
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