Emerging Roles of the Gut-Brain Axis (GBA) in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 9
Special Issue Editor
Special Issue Information
Dear Colleagues,
We invite researchers, clinicians, and scientists to contribute original articles, reviews, and perspectives to our upcoming Special Issue focused on the gut–brain axis (GBA) and its role in health and disease. The GBA is an intricate, bidirectional communication network between the gastrointestinal tract and the central nervous system, involving neural, hormonal, immune, and microbial pathways. Emerging evidence highlights the GBA's pivotal role in regulating mood, cognition, immune responses, and metabolic processes, while its dysregulation has been implicated in a broad spectrum of conditions—from depression, anxiety, and neurodegenerative disorders to irritable bowel syndrome and inflammatory bowel disease.
This issue seeks to explore the latest advances in understanding how the gut microbiota influences brain function and vice versa, and how this knowledge can be harnessed for novel diagnostic tools and therapeutic strategies. We particularly welcome submissions on microbiome research, psychobiotics, nutritional neuroscience, immune signaling, and gut-targeted interventions in neurological and psychiatric disorders.
Join us in advancing this exciting interdisciplinary field by sharing your work. Submissions will undergo rigorous peer review, and selected papers will be featured in a high-impact issue aimed at driving innovation in clinical and translational medicine.
Dr. Vinata Vedam-Mai
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut–brain axis
- gut microbiota
- brain function
- diagnostic tools
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