Molecular Research in Ocular Inflammation and Infection
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 9
Special Issue Editor
Interests: uveitis; macular edema; retinopathy; choroiditis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ocular inflammation is associated with a wide range of diseases and is recognized as the fifth leading cause of blindness in Western countries. Its underlying causes can be categorized into several main groups:
- Infectious causes: These are the most common and include pathogens such as Toxoplasma gondii, members of the herpesvirus family, Mycobacterium tuberculosis, and less frequently involved agents such as Bartonella species.
- Autoimmune disorders confined to the choroid-retina layer: Examples include acute posterior multifocal placoid pigment epitheliopathy, idiopathic multifocal choroiditis, and serpiginous choroiditis. Their pathophysiology is increasingly elucidated through optical coherence tomography (OCT) and indocyanine green angiography.
- Systemic autoimmune diseases: These involve ocular manifestations as part of systemic conditions, such as sarcoidosis, which has shown a rising incidence and prevalence in recent years.
- Neoplastic masquerade syndromes: These include conditions that mimic uveitis, most classically intraocular non-Hodgkin B-cell lymphoma, as well as systemic hematologic malignancies that delay diagnosis and specific treatment due to their atypical ocular presentations.
- Iatrogenic uveitis: This form of inflammation may be induced by novel anti-cancer immunotherapies, particularly immune checkpoint inhibitors.
Additionally, recent studies have described pseudo-uveitis masquerade syndromes in patients with genetic retinal dystrophies characterized by predominant neuroinflammation.
This Special Issue invites international contributions on all aspects of ocular inflammation and infection in both adults and children. Submissions may include (but are not limited to): original research, diagnostic advances, case reports or series, novel treatment approaches, and imaging innovations.
We hope that this international collaboration will contribute to deeper insights into the diagnosis and management of these complex and often rare conditions.
Dr. Christine Fardeau
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ocular infections
- uveitis
- choroiditis
- masquerade syndrome
- pseudo-uveitis
- intraocular lymphoma
- retinal dystrophy
- ocular inflammation
- neuroinflammation
- immunotherapy-induced uveitis
- autoimmune eye diseases
- sarcoidosis
- OCT
- indocyanine green angiography
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
