Repair Mechanisms of Stem Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 136
Special Issue Editors
Interests: immunomodulation; signalling pathways; OMICs and regenerative medicine; isolation and characterization of stem cells; innovative methodologies and bioengineering applications of stem cells; gene therapy; scaffolds and stem cells; tissue regeneration in disease modes; organoids
Special Issues, Collections and Topics in MDPI journals
2. Instituto Pluridisciplinar (UCM), Madrid, Spain
3. Grupo de Medicina Regenerativa, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 28041 Madrid, Spain
Interests: immunomodulation; neuroprotection; neurological diseases; cell signalling pathways; neurorepair; stem cells and neuroprottectants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Stem cell research is important for understanding the mechanisms of tissue regeneration in preclinical models. Regenerative medicine allows us to understand the reparative role that stem cells play in various tissues through the release of paracrine factors, such as the brain, heart, liver, kidneys, and peripheral organs. Furthermore, stem cells have the potential to differentiate into diverse cell types. The study of stem cell biology, including its roles in immunomodulation, protection, and signal transduction, allows us to understand their protective and regenerative capacities through the paracrine mechanisms of different stem cell types. This subject also includes the study of new protocols and methodologies that cover aspects ranging from the isolation and characterization of stem cells to the application of bioengineering, including gene therapy, such as studies with mesenchymal stem cells, hematopoietic stem cells, induced pluripotent stem cells (iPS cells), etc.
This Special Issue aims to compile such studies, including their biomedical applications. Proposals on differentiation protocols and new techniques for stem cell isolation are of particular interest, including innovative research strategies that culminate in a prospective look at the future of tissue regeneration. The study of the cellular and molecular mechanisms involved in stem cell repair in vitro and in preclinical models from an integrative perspective is also welcome, including OMIC techniques, metabolomics, and immune and cellular approaches. Submissions including molecular and cellular signalling pathways are also encouraged. Furthermore, innovations in biomaterials and 3D printing technologies enhance the regenerative capacity of scaffolds to promote stem cell growth and differentiation, leading to successful stem cell integration into damaged tissues and potentially improving the efficacy of stem cell therapies.
We intend for this Special Issue to serve as a vital resource for basic and clinical researchers involved in the field of regenerative medicine. We look forward to hearing from you and advancing this field, fostering its development.
Dr. Ana Flores
Prof. Dr. Jose Joaquin Merino
Guest Editors
Manuscript Submission Information
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Keywords
- stem cell biology
- stem cells
- stem cell therapy
- tissue regeneration
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