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Molecular Mechanisms of Skeletal Muscle Adaptation

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 54

Special Issue Editor


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Guest Editor
Institute of Integrative Neuroanatomy, Charité Medical School Berlin, 10115 Berlin, Germany
Interests: skeletal muscle; muscle physiology; excitation contraction coupling; exercise performance; neuromuscular signaling; neuromuscular physiology; contractile proteins; muscle proteins; skeletal muscle fibers; muscle damage; exercise; oxidative stress
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Special Issue Information

Dear Colleagues,

Skeletal muscle is an extraordinarily plastic tissue capable of responding rapidly to significant mechanical, metabolic, and hormonal stimuli through profound changes at the molecular, cellular, and functional levels. Understanding the molecular mechanisms that regulate these adaptive responses is essential not only in outlining the principles behind muscle physiology but also in developing therapeutic strategies in clinical settings.

In recent years, skeletal muscle research has benefited from significant advances in fields such as genomics, transcriptomics, and proteomics. These technologies have opened up new perspectives to reshape our understanding of the following topics:

- The molecular pathways that regulate muscle hypertrophy, atrophy, and regeneration;
- The interactions between muscle and other systems, such as the nervous, endocrine, and immune systems.

Despite the growing number of studies, there is still a lack of systematic collections integrating recent findings into a coherent, multidisciplinary framework.

For these reasons, we propose a Special Issue of the International Journal of Molecular Sciences (IJMS) entitled “Molecular Mechanisms Underlying Skeletal Muscle Adaptation”.

This Special Issue will be dedicated to showcasing original articles and reviews exploring the molecular basis underlying skeletal muscle adaptations under physiological and pathological conditions.

Our aim is to provide a platform for the following endeavours:

  1. Sharing innovative results;
  2. Stimulating dialogue between practitioners with molecular and functional approaches;
  3. Encouraging collaboration between researchers working in complementary fields.

Dr. Michele Salanova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skeletal muscle
  • adaptive responses
  • muscle physiology
  • genomics
  • transcriptomics
  • proteomics
  • molecular mechanisms

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Published Papers

This special issue is now open for submission.
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