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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Therapeutic Horizons of Oligosaccharides: Molecular Mechanisms and Therapeutic Potential

edited by

Abdelali Daddaoua

and

María Núñez-Núñez

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2311 | Submission Open

Keywords: oligosaccharides; bacterial infection; multidrug-resistant

(This special issue belongs to the Section Molecular Microbiology)

Role of Immune Cells in Cancers

edited by Helga Maria Schmetzer

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2243 | Submission Open

Keywords: cancer; immune monitoring; immune escape; immune activation

(This special issue belongs to the Section Molecular Oncology)

Advances in Kidney Transplantation

edited by Zeljko Kikic

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2217 | Submission Open

Keywords: chronic rejection; antibody-mediated rejection; immunosuppression; BK virus nephropathy (BKVAN); diagnostic challenges

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Editing for Cereal Crops

edited by

Ke Wang

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2204 | Submission Open

Keywords: gene-editing techniques; novel germplasm; quality; nutrition; agronomic traits

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Venom and Antivenom

edited by

Vance G. Nielsen

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2169 | Submission Open

Keywords: venom; antivenom; mass spectroscopy; spectrophotometry; thromboelastography; coagulation; neuromuscular junction

(This special issue belongs to the Section Molecular Toxicology)

Advances in Brassica Crop Metabolism and Genetics (Second Edition)

edited by

Bo Sun

and

Honghao Lv

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1995 | Submission Open

Keywords: brassica crop; genomics; transcriptomics; proteomics; metabolomics; gene editing; metabolite synthesis and regulation; phylogeny and taxonomy; physiological traits; biotic/abiotic stresses; biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Climate Change Mitigation Strategies in Grapevine Molecular, Biochemical, and Physiological Performance

edited by

Sandra Pereira

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1882 | Submission Open

Keywords: grapevine growth; climate change; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research in Epilepsy

edited by

Kinga Borowicz

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1879 | Submission Open

Keywords: epilepsy; epileptogenesis; antiepileptic drugs; drug resistance; interactions of antiepileptic drugs; multi-omics in epilepsy

(This special issue belongs to the Section Molecular Neurobiology)

Non-Coding RNAs’ Functionality—Diagnosis and Therapy in Cancer and Other Indications (2nd Edition)

edited by

Mohamed Raafat El-Gewely

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1854 | Submission Open

Keywords: non-coding RNAs (ncRNAs); long non-coding RNAs (lncRNAs); MicroRNAs (miRNAs); circular RNAs (circRNAs); epigenetic and post-transcriptional regulation; epithelial– mesenchymal transition (EMT); cell proliferation and Apoptosis; biomarkers and Liquid biopsy; RNA-based therapeutics; next-generation sequencing (NGS); CRISPR/Cas9 screening; single-cell RNA sequencing (scRNA-seq); RNA interference (RNAi); cancer stem cells; early cancer diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Obesity and Cancer Risk: Molecular Mechanisms and Perspectives

edited by

Hendrik Lehnert

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1728 | Submission Open

Keywords: epidemiology of obesity and cancer; experimental models of cancer in obesity; genetic and epigenetics of obesity and metabolic dysfunction associated cancer; tumor microenvironment; basis of metastatic spread of cancer in obesity; therapeutic modeling and targeting

(This special issue belongs to the Section Molecular Oncology)

miRNAs in Cancers: From Molecular Biology to Treatment

edited by

Laura Mosca

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1611 | Submission Open

Keywords: cancer; miRNA; epigenetic

(This special issue belongs to the Section Molecular Biology)

Bioactive Compounds from Foods Against Diseases

edited by Jongbin Lim

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1585 | Submission Open

Keywords: diet-related diseases; bioactive compounds; analytical techniques; functional foods; molecular interaction; health benefits

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Research on System Biology Methods and Tools for Integrating Omics Data

edited by Yuanyan Xiong

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1584 | Submission Open

Keywords: systems biology; multi-omics integration; network analysis; computational biology; bioinformatics tools; machine learning; precision medicine

(This special issue belongs to the Section Molecular Informatics)

Nutrition, Inflammation, and Chronic Kidney Disease

edited by

Denise Mafra

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1567 | Submission Open

Keywords: chronic kidney disease; inflammation; nutrients; bioactive compounds

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Traits in Animals and Aquatic Species, and Their Improvement Technologies

edited by

Lishi Yang

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1549 | Submission Open

Keywords: biotechnology; genetic breeding; stress responses; epigenetics; non-coding RNAs; gene regulation; molecular ecology; animals; aquaculture; development

(This special issue belongs to the Section Molecular Biology)

Melanoma: From Molecular Pathology to Therapeutic Approaches, 2nd Edition

edited by

Michael Eccles

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1546 | Submission Open

Keywords: melanoma; pathology; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Molecular Mechanisms of Genotoxicity

edited by Francesca Marcon and

Roberta Meschini

submission deadline 20 Jun 2026 | Viewed by 1537 | Submission Open

Keywords: DNA damage; DNA repair; genotoxicity; carcinogenesis; chronic degenerative diseases; human health; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Cardiac Repair and Regeneration: From Pathogenesis to Therapeutic Perspectives

edited by Marina Leone and Olaf Bergmann

submission deadline 20 Jun 2026 | Viewed by 1528 | Submission Open

Keywords: heart regeneration; cardiomyocyte proliferation; cell cycle; ischemic heart disease; myocardial infarction; stem cells; cardiac repair; polyploidization; tissue engineering; immune cells; metabolism; cell death

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Colorectal Cancer: Molecular and Cellular Basis

edited by Martina Lepore Signorile

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1496 | Submission Open

Keywords: colorectal cancer; molecular and cellular biology; tumor initiation; tumor progression; metastasis

(This special issue belongs to the Section Molecular Oncology)

Conversion and Valorization of Lignocellulosic Biomass

edited by

Loredana Marcolongo

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1490 | Submission Open

Keywords: lignocellulosic biomass; vegetal and agro processing wast; catalytic and biocatalytic conversion; value added products; lignocellulosic platform; bioprocessing; biorefinery; green chemistry; circular economy; bioeconomy

(This special issue belongs to the Section Biochemistry)

The Molecular and Cellular Pathophysiologic Mechanisms Underlying Ocular Diseases and Emerging Therapies (2nd Edition)

edited by

Snježana Kaštelan

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1466 | Submission Open

Keywords: eye disease; immunobiological features; molecular pathogenesis; biomarkers; clinical implications; emerging therapies; lacrimal gland; ocular tumors; glaucoma; diabetic retinopathy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Upper and Lower Airway Diseases in Allergy and Immunology: From Bench to Bedside

edited by

Giovanni Paoletti

Giulia Costanzo

and

Enrico Marco Heffler

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1465 | Submission Open

Keywords: unified airway disease; allergic rhinitis; asthma; chronic rhinosinusitis; eosinophilic; airway inflammation; airway epithelial barrier; immune dysregulation; respiratory microbiome; biomarkers; allergy and immunology

(This special issue belongs to the Section Molecular Immunology)

Pathogenesis and Molecular Therapy of Brain Tumor

edited by

Theo Kraus

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1434 | Submission Open

Keywords: brain tumor; glioma; glioblastoma; astrocytoma; oligodendroglioma; epigenetics; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Targeting Epigenetic Complexes and Alternative Protein Degradation Pathways in Medicinal Chemistry

edited by Jean Leandro Dos Santos

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1347 | Submission Open

Keywords: protein degradation; LYTAC; AUTAC; ATTEC; epigenetics; NuRD; HDAC; BRD; SWI/SNF; PRC2; chromatin; conjugates; lysosome; autophagy; drug discovery

(This special issue belongs to the Section Biochemistry)

Molecular Research on Orchid Plants: 2nd Edition

edited by Wen‑Chieh Tsai

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1320 | Submission Open

Keywords: orchid; genomics; genome; genes; tumor; inflammation; drug; transcriptomics

(This special issue belongs to the Section Molecular Plant Sciences)

Zebrafish as a Novel Model for Toxicological Research

edited by Leobardo Manuel Gómez-Oliván

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1280 | Submission Open

Keywords: zebrafish; toxicological assessment; organic and inorganic contaminants; oxidative stress; developmental toxicity; neurotoxicity; reproductive toxicity; genotoxicity; alternative testing models; One Health

(This special issue belongs to the Section Molecular Toxicology)

Cancer Models: Development and Applications

edited by

Yong Teng

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1234 | Submission Open

Keywords: tumor organoids; animal models of cancer; drug screening models; highly clinically relevant cancer models; technologies related to cancer model development

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biology of Oral Cancer

edited by Rafał Pęksa

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1198 | Submission Open

Keywords: oral cancer; molecular mechanisms; biomarkers; tumor microenvironment; therapy resistance; precision medicine; carcinogenesis; oral squamous cell carcinoma; epigenetics; microbiome; immunotherapy; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Antibacterial Nanomaterials for Medicinal Applications

edited by

Tsung-Rong Kuo

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1160 | Submission Open

Keywords: nanotechnology; antibacterial; nanomaterials; toxicity; biocompatibility; medicinal applications

(This special issue belongs to the Section Molecular Nanoscience)

Latest Molecular Research on Polymer Coatings

edited by

Joanna Karasiewicz

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1146 | Submission Open

Keywords: synthesis of specialty compounds; specialty compounds in industrial treatment; amphiphilic compounds; wettability (including solids and biomaterials); antimicrobial activity; surface activity; superwetting; high hydrophobic/hydrophilic/olrophobic/olephilic properties; special applications: self-cleaning; anti-icing; self-healing; biocidal; etc.

(This special issue belongs to the Section Materials Science)

Plant Breeding Strategies: Employment of Plant Adaptation Mechanisms to Biotic and Abiotic Stresses

edited by

Vidmantas Bendokas

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1140 | Submission Open

Keywords: marker-assisted selection; molecular breeding; whole-transcriptome analysis; RNA sequencing; DNA sequencing; plant stress response

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Cytokines in Inflammation and Diseases

edited by

Keiichi Yamanaka

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: inflammation; cytokine; complication; systemic inflammation; internal organ

(This special issue belongs to the Section Molecular Immunology)

Toxicology Research: Understanding and Predicting Compound-Induced Toxicity

edited by

Miriam Beatríz Virgolini

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1105 | Submission Open

Keywords: toxicity; adverse-outcome pathway; metals; pesticides; drugs of abuse; pharmaceuticals

(This special issue belongs to the Section Molecular Toxicology)

The Role of Bioactive Natural Products in Human Health

edited by

Eleonora Di Salvo

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1066 | Submission Open

Keywords: bioactive compound; human health; functional foods; nutraceutical products; food toxicology; antioxidant properties; anti-inflammation; antimicrobial molecules

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Signaling and Cellular Mechanisms in Asthma

edited by

Kapil Sirohi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 988 | Submission Open

Keywords: asthma; endotypes; pausi-immune asthma; nonatopic asthma; steroid insensitivity; neutrophilic asthma; innate lymphoid cells; Th2 cells

(This special issue belongs to the Section Molecular Immunology)

Protein–Protein Interactions in Human Cancer

edited by

Geng Wu

submission deadline 20 Jun 2026 | 1 articles | Viewed by 988 | Submission Open

Keywords: protein– protein interactions; protein– protein complexes; human cancer; signal transduction pathways; protein structure and function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metabolomics of Medicinal Plants

edited by

L. Gerardo Zepeda Vallejo

and

Elvia Becerra-Martínez

submission deadline 20 Jun 2026 | 2 articles | Viewed by 940 | Submission Open

Keywords: metabolomics; medicinal plants; nuclear magnetic resonance; mass spectrometry; bioinformatic; phenotyping; metabolic pathways; bioactive metabolites

(This special issue belongs to the Section Molecular Plant Sciences)

Multifaceted Roles of Extracellular Vesicles in Cancer and Other Diseases

edited by

Eleni Myrto Trifylli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 839 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer diagnostics; non-invasive tests; liquid biopsy; cancer therapy; biomarker discovery; nanotechnology; EV engineering; drug delivery; neurodegenerative diseases; cardiovascular diseases; infectious diseases; autoimmune diseases; precision diagnostics

(This special issue belongs to the Section Molecular Oncology)

Natural Antioxidants—Sources, Characteristics, and Biological Activity

edited by

Maciej Spiegel

submission deadline 20 Jun 2026 | 1 articles | Viewed by 787 | Submission Open

Keywords: natural antioxidants; oxidative stress; reactive oxygen species; inflammation; free radicals; structure– activity relationship; nutraceuticals; synergistic effects; plant-derived compounds; drug discovery

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Precision Cancer Medicine: Molecular Insights, Biological Events and Clinical Perspectives

edited by

Dimitrios H. Roukos

submission deadline 20 Jun 2026 | Viewed by 786 | Submission Open

Keywords: multi-omics at bulk level; single-cell multi-omics; precision oncology; precision immune-oncology; tumor molecular profiling

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Actinomycetes-Derived Natural Products

edited by Fong Tian Wong

submission deadline 20 Jun 2026 | 1 articles | Viewed by 782 | Submission Open

Keywords: actinomycetes; natural products; actinobacterial; genome mining; omics; secondary metabolites; genetic engineering; discovery; structural diversity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Biology of 3D Cell and Tissue Culture Systems: Benefits to Research and Disease Diagnostics

edited by

Thomas J. Goodwin

submission deadline 20 Jun 2026 | 1 articles | Viewed by 773 | Submission Open

Keywords: 3D physiological relevance vs. 2D biology; 3D research; and diagnostic systems; evolving 3D “ omics” applications; research and clinical medicine; drug applications; toxicity evaluations; “ Omics” ; spatial biology of 3D

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cutting-Edge Advances in Natural Bioactive Compounds

edited by

Joachim Storsberg

submission deadline 20 Jun 2026 | Viewed by 639 | Submission Open

Keywords: natural bioactive compounds; phytochemicals; fungal metabolites; antioxidant activity; anti-inflammatory agents; antimicrobial compounds; anti-cancer compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

RNA in Biology and Medicine (2nd Edition)

edited by

Roberto Patarca

and William A. Haseltine

submission deadline 20 Jun 2026 | 1 articles | Viewed by 628 | Submission Open

Keywords: noncoding RNAs; coding RNAs; RNA-based therapy; RNA vaccine; RNA structure; RNA function

(This special issue belongs to the Section Molecular Biology)

Molecular Dynamics Techniques in the Artificial Intelligence Era

edited by

Luciano Tavares Costa

Andrew S. Paluch

and Itamar Borges Junior

submission deadline 20 Jun 2026 | Viewed by 609 | Submission Open

Keywords: molecular dynamics; machine learning; force field; free energy; statistical mechanics; algorithm development; artificial intelligence

(This special issue belongs to the Section Molecular Informatics)

Natural Products and Drug Delivery Systems in Dental Diseases

edited by

Rafael Scaf De Molon

submission deadline 20 Jun 2026 | 1 articles | Viewed by 607 | Submission Open

Keywords: periodontitis; natural products; anti-inflammatory therapy; local drug delivery; gingival inflammation; regenerative periodontics; nanotechnology in dentistry; herbal medicine; antimicrobial agents; oral microbiome modulation; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Gastrointestinal Immunity: Balancing Homeostasis and Pathological States

edited by Mihai Danciu and Gabriel Becheanu

submission deadline 20 Jun 2026 | Viewed by 580 | Submission Open

Keywords: gastrointestinal immunity; mucosal barrier function; immune signaling pathways; gut microbiota; inflammatory bowel disease (IBD); colorectal cancer; cytokines and chemokines; immunopathology; targeted immunotherapy; biomarkers of gut inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

T-Cell Lymphoma: From Basic Science to Novel Therapeutics

edited by

Daniele Caracciolo

and

Andrea Duminuco

submission deadline 20 Jun 2026 | Viewed by 578 | Submission Open

Keywords: T-cell lymphoma; targeted therapy; immunotherapy; translational research; real-world experience

(This special issue belongs to the Section Molecular Oncology)

Leukemia: Molecular Immune Mechanisms

edited by

Mohammad Hojjat-Farsangi

submission deadline 20 Jun 2026 | Viewed by 574 | Submission Open

Keywords: leukemia; immune system; Genetic Mutations and Alterations; Immune Evasion Mechanisms; Immune Cell Dysfunction; Cytokine Networks; Bone Marrow Microenvironment; immunotherapy strategies

(This special issue belongs to the Section Molecular Immunology)

Advancements in Inflammatory and Oxidative Disease Research

edited by

Sandra Barbalho

submission deadline 20 Jun 2026 | 1 articles | Viewed by 545 | Submission Open

Keywords: diabetes; cancer; neurological diseases; inflammation; oxidative stress; endocrinology; gastroenterology; pulmonology; rheumatology; cardiology; neurology; nephrology; dermatology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 3051-3100 on page 62 of 67.

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