Multifaceted Roles of Extracellular Vesicles in Cancer and Other Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 102
Special Issue Editor
2. Laboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, Section of Medical Laboratories, School of Health & Caring Sciences, University of West Attica, Egaleo, Greece
3. Institute of Molecular Medicine and Biomedical Research, Athens, Greece
Interests: extracellular vesicles; precision medicine ; development of novel biomarkers; drug vectors ; immunotherapy; cholangiocarcinoma; HCC; biliary tract cancers; MASLD; chronic liver diseases
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) comprise highly heterogeneous nano-sized particles, encompassing exosomes, microvesicles, and apoptotic bodies, which have come into the spotlight in current oncological research due to their implications in cancer and their emerging role as next-generation diagnostic and therapeutic modalities. These vesicles are released by a wide variety of cells within the tumor and its microenvironment, playing a significant role in cell-to-cell crosstalk via their diverse embedded cargoes. These cargoes can modify the functional state of recipient cells and ultimately promote disease development and progression. A deeper understanding of their biological role in cancer, as well as in several other diseases, including neurodegenerative, cardiovascular, infectious, and autoimmune disorders, along with recent advancements in EV isolation, characterization, and engineering methodologies, will open up new horizons for the development of liquid-biopsy-based diagnostics and therapeutic tools. We welcome state-of-the-art research and high-impact contributions regarding EV-mediated diagnostics and therapeutics in oncology and other disease contexts in this Special Issue entitled “Multifaceted Roles of Extracellular Vesicles in Cancer and Other Diseases.”
Dr. Eleni Myrto Trifylli
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- extracellular vesicles
- exosomes
- cancer diagnostics
- non-invasive tests
- liquid biopsy
- cancer therapy
- biomarker discovery
- nanotechnology
- EV engineering
- drug delivery
- neurodegenerative diseases
- cardiovascular diseases
- infectious diseases
- autoimmune diseases
- precision diagnostics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
