Molecular Research in Epilepsy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 1043
Special Issue Editor
Special Issue Information
Dear Colleagues,
Despite the introduction of newer antiepileptic drugs with different mechanisms of action into treatment, the percentage of drug-resistant epilepsy still remains at around 30%. It cannot be ruled out that anticonvulsants administered chronically alter the expression of genes related to seizure processes and the synthesis of their protein products. Still, the most effective treatment for drug-resistant epilepsy remains the prevention of seizure generation and propagation, which requires very good knowledge of the mechanisms of epileptogenesis. However, despite significant progress in this field, knowledge of the pathophysiology of seizures is not yet sufficient.
The present Special Issue aims to present recent reports on the following:
- Mechanisms of epileptogenesis and seizure maturation;
- The molecular basis of drug resistance of seizures;
- Mechanisms of action of available antiepileptic drugs and their interactions with other drugs;
- Effects of seizures and antiepileptic drugs on genomics, proteomics, and metabolomics.
Prof. Dr. Kinga Borowicz
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- epilepsy
- epileptogenesis
- antiepileptic drugs
- drug resistance
- interactions of antiepileptic drugs
- multi-omics in epilepsy
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
