Upper and Lower Airway Diseases in Allergy and Immunology: From Bench to Bedside
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 67
Special Issue Editors
2. IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy
Interests: allergology and clinical immunology; asthma; chronic rhinosinusitis with nasal polyps
Special Issues, Collections and Topics in MDPI journals
Interests: allergology and clinical immunology; asthma; chronic rhinosinusitis with nasal polyps; immunology; rheumatology
Special Issues, Collections and Topics in MDPI journals
2. IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy
Interests: allergy; anaphylaxis; drug allergy; asthma; severe asthma; rhinosinusitis with and without nasal polyps; biologicals; precision medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue focuses on the complex interplay between upper and lower airways in allergic and immunologic diseases. The respiratory tract functions as a unified system, and increasing evidence highlights how inflammation in one part of the airways can influence the other. Conditions such as allergic rhinitis, chronic rhinosinusitis, asthma, and eosinophilic airway disorders often coexist, suggesting shared immunopathological mechanisms. This collection aims to explore recent advances in the understanding of airway inflammation, novel diagnostic approaches, and emerging therapeutic strategies. We invite original research articles, reviews, and clinical studies that investigate the pathophysiology, biomarkers, and treatment of upper and lower airway diseases in the context of allergy and immunology. Contributions discussing the role of the epithelial barrier, immune dysregulation, and the microbiome are especially welcome. This Special Issue offers a valuable platform for clinicians and researchers to share insights and promote an integrated approach to respiratory allergic and immunologic conditions. Please note that pure clinical or model studies are unsuitable for this journal, but clinical submissions with biomolecular studies are welcome.
Dr. Giovanni Paoletti
Dr. Giulia Costanzo
Dr. Enrico Marco Heffler
Guest Editors
Manuscript Submission Information
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Keywords
- unified airway disease
- allergic rhinitis
- asthma
- chronic rhinosinusitis
- eosinophilic
- airway inflammation
- airway epithelial barrier
- immune dysregulation
- respiratory microbiome
- biomarkers
- allergy and immunology
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