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Colorectal Cancer: Molecular and Cellular Basis

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 25 November 2025 | Viewed by 38

Special Issue Editor


E-Mail Website
Guest Editor
Medical Genetics, National Institute of Gastroenterology—IRCCS “Saverio de Bellis” Research Hospital, Castellana Grotte, 70013 Bari, Italy
Interests: colorectal cancer

Special Issue Information

Dear Colleagues,

Colorectal cancer is one of the leading causes of cancer-related morbidity and mortality worldwide, with a complex interplay of genetic, epigenetic, and environmental factors driving its initiation and progression. Despite significant advances in diagnosis and treatment, colorectal cancer remains a formidable challenge in oncology, underscoring the urgent need for a deeper understanding of its molecular and cellular underpinnings. This Special Issue, “Colorectal Cancer: Molecular and Cellular Basis”, brings together cutting-edge research and reviews that explore the mechanisms governing tumor initiation, progression, metastasis, and resistance to therapy. By presenting novel insights and state-of-the-art research, this collection aspires to enhance our understanding of colorectal cancer at the molecular and cellular levels, paving the way for innovative strategies in diagnosis, management, and therapy. Through collaboration and knowledge-sharing, this issue seeks to support the ongoing fight against colorectal cancer.

We are pleased to invite you to contribute to our Special Issue in the International Journal of Molecular Sciences, entitled “Colorectal Cancer: Molecular and Cellular Basis”. We encourage you to submit original articles or reviews that provide an overview of current knowledge regarding the molecular network of colorectal cancer, including cellular signaling pathways involved in CRC initiation, progression, and metastasis. We also encourage submissions exploring potential strategies for the treatment of colorectal cancer.

Dr. Martina Lepore Signorile
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • colorectal cancer
  • molecular and cellular biology
  • tumor initiation
  • tumor progression
  • metastasis

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Published Papers

This special issue is now open for submission.
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