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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Pain Medicine: Diagnostic and Management Innovations

edited by Yuchen Lee, Dongwoo Nam and Cheng-Hao Tu

submission deadline 31 Aug 2026 | Viewed by 175 | Submission Open

Keywords: pain medicine; chronic pain; neuropathic pain; nociplastic pain; biomarkers; imaging; quantitative sensory testing; artificial intelligence; digital health; multimodal analgesia; neuromodulation; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Hypertrophic Cardiomyopathy

edited by Ibraim Masciarelli Francisco Pinto

submission deadline 31 Aug 2026 | Viewed by 163 | Submission Open

Keywords: hypertrophic cardiomyopathy; multimodality imaging; genetic testing; cardiac MRI; risk stratification; myosin inhibitor; septal reduction therapy; sudden cardiac death; echocardiography; precision cardiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Epidemiological Diagnostics: Detecting and Controlling Infectious Diseases, 2nd Edition

edited by

Sri Banerjee

and W. Sumner Davis

submission deadline 31 Aug 2026 | Viewed by 160 | Submission Open

Keywords: epidemiological diagnostics; disease control; clinical practice and patient care; public health; infectious diseases

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

New Insights into the Diagnosis and Management of Head and Neck Cancer

edited by Yung-An Tsou

submission deadline 31 Aug 2026 | Viewed by 157 | Submission Open

Keywords: oropharyngeal cancer; HPV; radiotherapy optimization; multidisciplinary approaches; transoral robotics surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Functional Gastrointestinal Disorders (FGIDs): Diagnosis and Pathophysiology, Second Edition

edited by Gengqing Song

submission deadline 30 Sep 2026 | 4 articles | Viewed by 28813 | Submission Open

Keywords: functional gastrointestinal disorders; diagnosis; treatment approach; ROME criteria

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Presentation, Management and Prognosis of Infective Endocarditis

edited by

Arian Arjomandi Rad

, Alexander Weymann and Thanos Athanasiou

submission deadline 30 Sep 2026 | 2 articles | Viewed by 15431 | Submission Open

Keywords: infective endocarditis; clinical presentation; diagnostic modalities; antibiotic stewardship; surgical interventions; prognostic indicators

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Infectious Disease Diagnosis Technologies

edited by

Dakai Liu

and Fermina Maria Mazzella

submission deadline 30 Sep 2026 | 7 articles | Viewed by 12422 | Submission Open

Keywords: molecular diagnosis; biomarkers; microbial culture and identification; high-throughput sequencing; infectious diseases; artificial intelligence; digital image; radiological imaging; point-of-care testing

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Diagnostic Methods for Laboratory Medicine

edited by

Syed M. Shahid

submission deadline 30 Sep 2026 | 1 articles | Viewed by 11800 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; prevision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Laboratory Medicine)

Soft Tissue Sarcoma: From Diagnosis to Prognosis

edited by

Consolato M. Sergi

submission deadline 30 Sep 2026 | 3 articles | Viewed by 11267 | Submission Open

Keywords: soft tissue; mesenchyme; bone; pathogenesis; miRNA; imaging; diagnosis; therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Prognosis of Hematological Disease

edited by Sapha Shibeeb

submission deadline 30 Sep 2026 | 4 articles | Viewed by 10269 | Submission Open

Keywords: hematological diseases; leukaemia; molecular diagnostics; next-generation sequencing (NGS); precision medicine; predictive biomarkers; AI-assited diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovative Diagnostic Approaches in Retinal Diseases

edited by

Benedetto Falsini

and Andrea Cusumano

submission deadline 30 Sep 2026 | 6 articles | Viewed by 8359 | Submission Open

Keywords: retinal diseases; electrophysiology; imaging; optical coherence tomography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Diagnostics: From Algorithms to Clinical Impact

edited by

Ali Athar

, David Brown and

Hanem Ellethy

submission deadline 30 Sep 2026 | 7 articles | Viewed by 7737 | Submission Open

Keywords: machine learning in healthcare; artificial intelligence in diagnostics; medical imaging and deep learning; generative AI in medicine; multimodal data integration; explainable and trustworthy AI; translational medical AI; clinical decision support systems; secure and privacy-compliant data utilization

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Imaging Diagnosis of Dermatology

edited by Linda Tognetti

submission deadline 30 Sep 2026 | 4 articles | Viewed by 7094 | Submission Open

Keywords: high-resolution imaging; non-invasive diagnosis; LC-OCT; RCM; OCT; US

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Hematologic Malignancies

edited by

Ankur Varma

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6440 | Submission Open

Keywords: acute myeloid leukemia; chronic myeloid leukemia; myelodysplastic syndrome; myeloproliferative neoplasm; Hodgkin's lymphoma; non-Hodgkin's lymphoma; acute lymphocytic leukemia; chronic lymphocytic leukemia; bone marrow failure syndrome; juvenile myelomonocytic leukemia

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Management of Endometrial Diseases

edited by

Kotaro Kitaya

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6381 | Submission Open

Keywords: endometrial diseases; artificial intelligence; hysteroscopy; ultrasound; minimally invasive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Sleep and Respiratory Medicine

edited by Cheng-Yu Tsai

submission deadline 30 Sep 2026 | 4 articles | Viewed by 6078 | Submission Open

Keywords: sleep and respiratory disorders; chest medicine; AI in healthcare; digital technology; precision diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Applications of Optical Coherence Tomography and Optical Coherence Tomography Angiography in Ophthalmology

edited by

Daniela Bacherini

submission deadline 30 Sep 2026 | 5 articles | Viewed by 5381 | Submission Open

Keywords: OCT; OCTA; ophthalmology; diagnostics; clinical applications

(This special issue belongs to the Section Biomedical Optics)

Diagnosis, Prognosis and Management of Cardiovascular Disease in Patients with Rheumatic Conditions

edited by

Patrick H. M. C. Dessein

Miguel Angel Gonzalez-Gay

and

Iván Ferraz-Amaro

submission deadline 30 Sep 2026 | 2 articles | Viewed by 5054 | Submission Open

Keywords: rheumatoid arthritis; rheumatic conditions; cardiovascular risk factors; atherosclerosis; left ventricular structure and function; arterial function; cardiovascular events; ischemic heart disease; ischemic stroke; heart failure; peripheral vascular disease; venous thrombotic disease; cardiovascular drugs; antirheumatic agents

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Digital Innovation in Salivary Diagnostics for Oral and Systemic Health

edited by

Corina Marilena Cristache

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4993 | Submission Open

Keywords: saliva diagnosis; oral disease; systemic diseases; artificial intelligence; AI driven diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Revolutionizing Male Infertility: Novel Mechanistic Insights, Diagnostic Innovations, and Management Strategies

edited by

Athanasios Zachariou

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4742 | Submission Open

Keywords: male infertility; andrology; reproductive health; testis; spermatozoa; semen analysis; TESE; mTESE; ultrasound; artificial intelligence; IVF

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Radiomics and Artificial Intelligence Applications in the Diagnosis of Brain Lesions

edited by

Calin G. Buzea

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4496 | Submission Open

Keywords: brain lesions; biomarker; prognosis; diagnosis; radiomics; artificial intelligence

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Physiological Sound Processing for Medical Diagnostics: Innovations, Challenges, and Applications

edited by

Oliver Faust

and Prabal Datta Barua

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4253 | Submission Open

Keywords: heart sounds; lung sounds; cough analysis; sleep apnea and snoring; wearable devices; explainability and ethical AI; standardization and clinical validation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostics Advances in Peripheral Nerve Injuries

edited by

Jean Noël Goubier

submission deadline 30 Sep 2026 | 2 articles | Viewed by 4243 | Submission Open

Keywords: peripheral nerve injuries; diagnosis challenges; magnetic resonance imaging (MRI); electromyography (EMG); brachial plexus injury; nerve trunk lesions; radicular lesions; nerve recovery assessment; advances in nerve imaging; EMG-guided treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancing Diagnostics in Neuroimaging

edited by

Ali Y Mian

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4159 | Submission Open

Keywords: neuroimaging; magnetic resonance imaging (MRI); positron emission tomography (PET); radiomics; neurological disorders; precision medicine; quantitative biomarkers; multimodal integration

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Treatment, and Management of Hair Disorders

edited by Neil Jairath and

Vignesh Ramachandran

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4135 | Submission Open

Keywords: hair loss; alopecia; management; cicatricial; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Management of Liver Diseases

edited by

Po-Heng Chuang

submission deadline 30 Sep 2026 | 5 articles | Viewed by 3669 | Submission Open

Keywords: liver parenchyma diseases; fatty liver; hepatitis; intrahepatic space-occupying lesions; abscess liver cancer; biomarkers; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Trends in Cardiovascular Imaging: 2nd Edition

edited by

Hans-Christoph Becker

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3644 | Submission Open

Keywords: cardiac CT; cardiac MRI; hybrid and multimodality imaging; artificial intelligence and machine learning; coronary artery disease; myocardial tissue characterization; congenital heart disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Contemporary Clinical Anatomy in Diagnostic Practice: Imaging, Artificial Intelligence, and Diagnostic Interpretation

edited by

Piotr Karauda

submission deadline 30 Sep 2026 | 1 articles | Viewed by 3308 | Submission Open

Keywords: clinical anatomy; diagnostic interpretation; medical imaging; artificial intelligence; diagnostic accuracy; anatomical variability; translational diagnostics; radiological anatomy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases, Second Edition

edited by

Stefano Francesco Crinò

submission deadline 30 Sep 2026 | 4 articles | Viewed by 2858 | Submission Open

Keywords: endoscopic ultrasound; eRCP; radiomics; tissue acquisition; artificial intelligence; magnetic resonance imaging; cholangioscopy; pancreatic cancer; pancreatic cysts; hepatocellular carcinoma; cholangiocarcinoma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Insights into Imaging Diagnosis of Heart Disease

edited by

Michael Henein

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2822 | Submission Open

Keywords: cardiovascular imaging including echocardiography and CTCA; cardiovascular imaging; echocardiography; cardiac magnetic resonance; myocardial perfusion imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging-Guided Diagnosis and Precision Assessment in Spine and Joint Disorders

edited by Giuliano Lo Bianco, Timothy Deer and Kenneth B. Chapman

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2818 | Submission Open

Keywords: imaging-guided diagnostics; precision pain medicine; chronic pain; spine and joint disorders; artificial intelligence in imaging; radiomics and imaging biomarkers; neuromodulation and image-guided interventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Allergy and Asthma: Clinical Diagnostics and Management

edited by

Askin Gulsen

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2801 | Submission Open

Keywords: allergy; asthma; precision medicine; biomarkers; airway inflammation; clinical diagnostics; biologic therapies; phenotyping; disease management; immunology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancing Blood-Based Diagnostics: Innovations, Challenges and Clinical Impact

edited by Sapha Shibeeb

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2455 | Submission Open

Keywords: diagnostic biomarkers; analytical performance; test interpretability; prognostic markers; translational diagnostics; artificial intelligence in diagnostics; precision medicine; clinical decision-making

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Pain Medicine: Diagnosis and Management

edited by Alessandro Dario

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2434 | Submission Open

Keywords: neuropathic pain; fibromialgia; low back pain; nociplastic pain; artificial intelligence in pain medicine; evidence-based consensus guidelines; pain measuring; cancer pain medicine; interventional pain medicine; topic analgesic for chronic pain; SPECT/CT scan

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Research Updates in Vestibular Dysfunction: Diagnostic Breakthroughs

edited by

Jun Wang

and

Sulin Zhang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2359 | Submission Open

Keywords: vestibular disorders; vertigo; biomarkers; molecular diagnostics; vestibular compensation; Meniere’ s disease; BPPV; vestibular migraine; PPPD; dizziness; balance

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Hematology and Oncology, 2nd Edition

edited by Chohao Lee

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2317 | Submission Open

Keywords: hematological malignancies; lymphoma; leukemia; multiple myeloma; precision medicine; immunotherapy; genomics; targeted therapies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Multilayered Insights into Next-Generation Sequencing (NGS) and Endocrine Tumors/Malignancies: From Molecular Mechanisms to Precision Diagnosis

edited by

Sorina Schipor

and

Dana Manda

submission deadline 30 Sep 2026 | Viewed by 2253 | Submission Open

Keywords: thyroid; adrenal; pituitary; parathyroid; germline; somatic; gene; molecular biology; diagnosis; hormone; gene

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diabetes Mellitus: Clinical Diagnostics and Management

edited by

Syed M. Shahid

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2216 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; precision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis, Treatment and Management of Gastrointestinal Diseases

edited by

Carmen Fierbinteanu-Braticevici

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2120 | Submission Open

Keywords: gastrointestinal diseases; liver diseases; biomarkers in GI disease; imaging in GI diagnosis (CT; MRI; ultrasound); non-invasive diagnostic tools; GI Endoscopic procedures; treatment approaches; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Gastrointestinal Pathology

edited by

Ivan R. Ilić

and

Pavle Randjelovic

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1786 | Submission Open

Keywords: gastroesophageal reflux disease; gastritis; dysplasia; gastric cancer; inflammatory bowel disease; microscopic colitis; microbiota; celiac disease; colorectal cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancing Medical Imaging with AI: From Cutting-Edge Algorithms to Clinical Integration

edited by

Kyong Joon Lee

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1712 | Submission Open

Keywords: artificial intelligence; medical imaging; deep learning; computer-aided diagnosis (CADx); diagnostic imaging; clinical validation; medical image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovative Diagnostic Imaging Technology in Musculoskeletal Tumors

edited by

Min Wook Joo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1630 | Submission Open

Keywords: musculoskeletal tumors; diagnostic imaging; innovative technology; advanced imaging modalities; tumor classification; tumor staging; imaging protocols; image analysis techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Gastrointestinal Endoscopy

edited by

Gwang Ha Kim

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1524 | Submission Open

Keywords: artificial intelligence; bariatric endoscopy; gastrointestinal bleeding; endoscopic imaging; endoscopic resection; endoscopic ultrasonography; gastrointestinal tumor; third-space endoscopy

(This special issue belongs to the Section Biomedical Optics)

Obstetrics in the 21st Century: New Challenges and Translational Perspectives in Diagnostics

edited by

Edward Araujo Júnior

and

Alex Sandro Rolland Souza

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1476 | Submission Open

Keywords: obstetrics; high-risk pregnancies; ultrasound; magnetic resonance imaging; pathology; immunology; experimental; genomics; biomarkers; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Laboratory Markers of Human Disease—2nd Edition

edited by

Mina Hur

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1365 | Submission Open

Keywords: laboratory biomarkers; genomics; proteomics; molecular diagnostics; clinical chemistry

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Treatment of Kidney Disease—2nd Edition

edited by

Giuseppe Stefano Netti

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1345 | Submission Open

Keywords: kidney diseases; acute kidney injury; nephropathy; biomarkers; diagnosis; chronic renal failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound Imaging: Current Status and Future Perspectives

edited by Christoph Frank Dietrich

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1214 | Submission Open

Keywords: elastography; CEUS; fat quantification; radiomics/ultrasomics; point-of-care ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Maternal-Fetal Medicine: Diagnosis, Prognosis and Clinical Features

edited by Antonio Braga

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1164 | Submission Open

Keywords: maternal– fetal medicine; prenatal diagnosis; fetal ultrasound and doppler; prediction models; high-risk pregnancy; perinatal outcomes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

EEG Analysis in Diagnostics, 2nd Edition

edited by

Jae-Ho Han

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1133 | Submission Open

Keywords: advanced EEG Techniques; the characterization of EEG signal patterns; the identification of EEG signal abnormalities; functional connectivity analysis in EEG; sleep studies based on EEG; EEG in epilepsy diagnosis and monitoring; neurofeedback and EEG in cognitive enhancement; event-related potentials in clinical EEG; understanding pathophysiology via EEG

(This special issue belongs to the Section Medical Imaging and Theranostics)

Autopsy Pathology's Paradigm Shift: Are AI and New Technologies Forging a New Era?

edited by

Vincenzo Arena

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1109 | Submission Open

Keywords: autopsy pathology; AI; artificial intelligence; immunohistochemistry; molecular pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 301-350 on page 7 of 13.

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