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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Early Diagnosis of Sepsis: Current Status and Challenges

edited by

Andrea Piccioni

and

Gloria Rozzi

submission deadline 30 Nov 2025 | Viewed by 164 | Submission Open

Keywords: sepsis; early diagnosis of sepsis; biomarkers; sepsis mortality; serum presepsin; SOFA score

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Diagnostic Techniques and Endoscopic Management for Gastrointestinal Diseases

edited by

Micheal Tadros

submission deadline 30 Nov 2025 | Viewed by 161 | Submission Open

Keywords: endoscopy; gastrointestinal disease; diagnostic techniques

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Laboratory Diagnosis of Infections

edited by Mònica Balaguer Gargallo

submission deadline 30 Nov 2025 | Viewed by 160 | Submission Open

Keywords: infections; laboratory diagnosis; biochemical markers; bacterial resistance

(This special issue belongs to the Section Clinical Laboratory Medicine)

Bacterial Infections and Antimicrobial Resistance: Diagnosis and Management

edited by

Georgina Tzanakaki

submission deadline 30 Nov 2025 | Viewed by 151 | Submission Open

Keywords: bacterial infections; antimicrobial resistance (AMR); diagnostic innovations; molecular diagnostics; antimicrobial stewardship; multidrug-resistant pathogens; alternative therapies; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Digital Innovation in Salivary Diagnostics for Oral and Systemic Health

edited by

Corina Marilena Cristache

submission deadline 30 Nov 2025 | Viewed by 145 | Submission Open

Keywords: saliva diagnosis; oral disease; systemic diseases; artificial intelligence; AI driven diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Imaging of Autoimmune Diseases

edited by Simone Appenzeller

submission deadline 30 Nov 2025 | Viewed by 143 | Submission Open

Keywords: autoimmune diseases; systemic lupus erythematosus; systemic sclerosis; diagnosis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Treatment of Kidney Disease—2nd Edition

edited by

Giuseppe Stefano Netti

submission deadline 30 Nov 2025 | Viewed by 131 | Submission Open

Keywords: kidney diseases; acute kidney injury; nephropathy; biomarkers; diagnosis; chronic renal failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Prognosis of Steatotic Liver Disease

edited by

Helma Pinchemel Cotrim

submission deadline 30 Nov 2025 | Viewed by 118 | Submission Open

Keywords: steatotic liver disease— SLD; steatohepatitis; steatosis; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Soft Tissue and Bone Sarcomas: Advances in Diagnosis, Treatment, and Prognosis

edited by

Andrea Angelini

submission deadline 30 Nov 2025 | Viewed by 115 | Submission Open

Keywords: soft tissue sarcomas; bone sarcomas; diagnosis; prognosis; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hepatocellular Carcinoma: Diagnosis and Management

edited by Po-Ming Chen

submission deadline 30 Nov 2025 | Viewed by 109 | Submission Open

Keywords: hepatocellular carcinoma; chronic infection; non-alcoholic steatohepatitis; diagnostic and therapeutic strategies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Hearing Diseases

edited by

Mehdi Abouzari

submission deadline 30 Nov 2025 | Viewed by 103 | Submission Open

Keywords: artificial intelligence; hearing loss; diagnosis; machine learning; auditory neuroscience; speech recognition; cochlear implants; data science; computational algorithm

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Imaging in Oral Diseases

edited by Xavier Roselló-LLabres and

José López López

submission deadline 30 Nov 2025 | Viewed by 96 | Submission Open

Keywords: CBCT 3D maxillofacial imaging; virtual diagnostic simulation; social media pathology image sharing; oral disease diagnostic algorithms; AI-driven oral pathology detection; dental radiographic caries analysis; digital oral lesion segmentation; cross-disciplinary imaging workflows; tele-radiology collaboration platforms; salivary gland scintigraphy applications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Revolutionizing Male Infertility: Novel Mechanistic Insights, Diagnostic Innovations, and Management Strategies

edited by

Athanasios Zachariou

submission deadline 30 Nov 2025 | Viewed by 92 | Submission Open

Keywords: male infertility; andrology; reproductive health; testis; spermatozoa; semen analysis; TESE; mTESE; ultrasound; artificial intelligence; IVF

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis—2nd Edition

edited by

Stefano Elia

submission deadline 30 Nov 2025 | Viewed by 92 | Submission Open

Keywords: thoracic surgery; lung cancer; pleural diseases; mediastinal malignancies; surgical outcome

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Precision Diagnosis of Head and Neck Tumors: From Clues to Clarity

edited by

Alfio Ferlito

and

Orlando Guntinas-Lichius

submission deadline 30 Nov 2025 | 1 articles | Viewed by 89 | Submission Open

Keywords: head and neck cancer; screening; radiomics; human papillomavirus; liquid biopsy; de-escalation; clinical guidelines; sentinels node; quality of life

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Current Status and Challenges of Heart Disease Diagnosis

edited by

Giuseppe Sgarito

submission deadline 30 Nov 2025 | Viewed by 87 | Submission Open

Keywords: heart disease; cardiovascular diagnosis; cardiac imaging; artificial intelligence; biomarkers; end-stage heart failure; electrophysiology; sudden cardiac death; tissue characterization; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Optical Imaging Technologies in Ophthalmology and Neuroscience: Advances and Applications

edited by

Jae-Ho Han

submission deadline 30 Nov 2025 | Viewed by 85 | Submission Open

Keywords: optical imaging; ophthalmology; neuroscience; diagnosis; prognosis

(This special issue belongs to the Section Biomedical Optics)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 30 Nov 2025 | Viewed by 80 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Functional and Structural MR Image Analysis

edited by

Xingfeng Li

submission deadline 30 Nov 2025 | Viewed by 76 | Submission Open

Keywords: functional MRI; structural MRI; image analysis; radiomics; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Latest Innovations in Interventional Oncology

edited by

Pierleone Lucatelli

and

David C. Madoff

submission deadline 30 Nov 2025 | Viewed by 68 | Submission Open

Keywords: contrast-enhanced ultrasound (CEUS); hybrid PET-MRI oncology imaging; optical coherence tomography (OCT) diagnostics; AI-driven lesion segmentation; radiomics-based tumor profiling; liquid biopsy innovations; endovascular biomarker sampling; molecular imaging specificity; real-time tumor characterization; image-guided diagnostic paradigms

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostics Advances in Peripheral Nerve Injuries

edited by

Jean Noël Goubier

submission deadline 30 Nov 2025 | 1 articles | Viewed by 64 | Submission Open

Keywords: peripheral nerve injuries; diagnosis challenges; magnetic resonance imaging (MRI); electromyography (EMG); brachial plexus injury; nerve trunk lesions; radicular lesions; nerve recovery assessment; advances in nerve imaging; EMG-guided treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Diagnosis and Treatment in Surgical Oncology

edited by Spiros G. Delis

submission deadline 30 Nov 2025 | Viewed by 60 | Submission Open

Keywords: diagnosis; surgical oncology; surgical techniques; medical imaging; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI and Big Data in Medical Diagnostics

edited by

Miguel Mascarenhas

, Hélder Cardoso and

Guilherme Macedo

submission deadline 30 Nov 2025 | Viewed by 54 | Submission Open

Keywords: artificial intelligence; big data; diagnosis; convolutional neural networks; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in the Diagnosis and Prognosis of Lung Cancer

edited by Naomi Takemura

submission deadline 10 Dec 2025 | Viewed by 77 | Submission Open

Keywords: lung cancer; molecular biomarkers; artificial intelligence; early detection; precision detection; medical imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Tuberculosis Detection and Diagnosis 2025

edited by

Kanagavel Murugesan

submission deadline 30 Dec 2025 | 2 articles | Viewed by 3453 | Submission Open

Keywords: immunological testing: TST; IGRA; microscopic testing: sputum smear microscopy; AFB staining; molecular testing: NAATs; including LAMP and GeneXpert MTB/RIF; fluorescence in situ hybridization (FISH); culture-based testing: BACTEC MGIT; imaging techniques: X-rays; CT; advanced testing technologies: NGS; mass spectrometry

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Anatomy—Third Edition

edited by

Kyu-ho Yi

submission deadline 31 Dec 2025 | 19 articles | Viewed by 79877 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis of Gastrointestinal Diseases—2nd Edition

edited by

Huarong Chen

submission deadline 31 Dec 2025 | 20 articles | Viewed by 53558 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Characteristics of Headache and Diagnosis of Primary and Secondary Headache Disorders

edited by

Elena R. Lebedeva

submission deadline 31 Dec 2025 | 9 articles | Viewed by 43129 | Submission Open

Keywords: primary headache disorders; secondary headache disorders; migraine-like headache; tension-type headache; migraine; headache; characteristics of headache

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnostic Imaging of Gastrointestinal Diseases

edited by

Adrian Saftoiu

Bogdan Silviu Ungureanu

and

Irina M. Cazacu

submission deadline 31 Dec 2025 | 13 articles | Viewed by 33146 | Submission Open

Keywords: gastrointestinal diseases; gastrointestinal malignancies; endoscopy; endoscopic ultrasound; confocal laser endomicroscopy; ERCP; ultrasound; CEUS; CT; MRI

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Artificial Intelligence in Healthcare

edited by

Kelvin K. L. Wong

and

Dhanjoo N. Ghista

submission deadline 31 Dec 2025 | 8 articles | Viewed by 17944 | Submission Open

Keywords: artificial intelligence; AI-driven radiomics; healthcare; digital radiology; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Pathological Image Analysis—2nd Edition

edited by

Masayuki Tsuneki

submission deadline 31 Dec 2025 | 6 articles | Viewed by 13897 | Submission Open

Keywords: histopathology; cytopathology; molecular pathology; surgical pathology; digital pathology; microscopy; whole slide image (WSI); clinical data; computer vision; deep learning; machine learning; computation; mathematics; domain adaptation; segmentation; classification; pattern recognition; explainable AI; reconstruction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Developments in the Diagnosis of Skin Tumors

edited by

Sorina Danescu

submission deadline 31 Dec 2025 | 7 articles | Viewed by 13845 | Submission Open

Keywords: basal cell carcinoma; melanoma; benign tumors; cutaneous squamous cell carcinoma; Bowen’ s disease; actinic keratosis; diagnosis; biomarkers; imaging techniques; molecular diagnostics; histopathology; precision medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence Advances for Medical Computer-Aided Diagnosis—2nd Edition

edited by

Mugahed A. Al-antari

submission deadline 31 Dec 2025 | 6 articles | Viewed by 12001 | Submission Open

Keywords: image classification; image segmentation; medical image processing; biomedical optical imaging; medical signal processing; artificial intelligence; deep learning; machine learning; computer-aided diagnosis; explainable artificial intelligence

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Inflammatory Pathologies

edited by Uday Nagesh Shivaji

submission deadline 31 Dec 2025 | 6 articles | Viewed by 11726 | Submission Open

Keywords: systemic chronic inflammation; biomarkers of inflammation; imaging in inflammatory pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Presentation, Management and Prognosis of Infective Endocarditis

edited by

Arian Arjomandi Rad

, Alexander Weymann and Thanos Athanasiou

submission deadline 31 Dec 2025 | 2 articles | Viewed by 11482 | Submission Open

Keywords: infective endocarditis; clinical presentation; diagnostic modalities; antibiotic stewardship; surgical interventions; prognostic indicators

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Orthopedics and the Musculoskeletal System: Diagnosis, Prognosis, and Mechanisms

edited by Nahum Rosenberg

submission deadline 31 Dec 2025 | 7 articles | Viewed by 10636 | Submission Open

Keywords: muscle biology; muscle rehabilitation; orthopedic imaging; orthopedic diagnosis; orthopedic trauma; fracture healing

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Imaging: Trends, Impact, and Application in Medical and Biomedical Diagnostics

edited by

Naresh Kumar Ravichandran

submission deadline 31 Dec 2025 | 6 articles | Viewed by 10304 | Submission Open

Keywords: vascular and tumor imaging; drug testing; blood flow characterization; tissue characterization and cell migration analysis; fluorescence microscopy (FM); optical coherence tomography (OCT); ultrasound imaging (sonography); multiphoton microscopy (MPM); photoacoustic tomography (PAT); computed tomography (CT); conebeam computed tomography (CBCT); magnetic resonance imaging (MRI); endoscopy; scanning laser ophthalmoscopy; super-resolution microscopy; hyperspectral imaging; diffuse optical tomography; spectroscopy; structured illumination microscopy (SIM); laser doppler imaging; artificial intelligence; machine learning; algorithm development

(This special issue belongs to the Section Biomedical Optics)

Advances in Fetal Diagnosis and Therapy

edited by Elisa Montaguti

submission deadline 31 Dec 2025 | 4 articles | Viewed by 9981 | Submission Open

Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence for Clinical Diagnostic Decision Making

edited by

Md Mohaimenul Islam

and

Ming-Chin Lin

submission deadline 31 Dec 2025 | 4 articles | Viewed by 9452 | Submission Open

Keywords: artificial intelligence; machine learning; clinical decision support systems; health disparity; medical imaging; disease diagnosis; medical errors; patient safety

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Latest Advances and Prospects in Cardiovascular Imaging

edited by Carlo Liguori

submission deadline 31 Dec 2025 | 5 articles | Viewed by 8903 | Submission Open

Keywords: cardiovascular imaging; cardiovascular magnetic resonance; coronary angiography; echocardiography; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

The Role of AI in Ultrasound

edited by

Hyuksool Kwon

submission deadline 31 Dec 2025 | 4 articles | Viewed by 8797 | Submission Open

Keywords: artificial intelligence; medical ultrasound; diagnostic imaging; automated image interpretation; predictive modeling; personalized medicine; clinical workflow optimization; healthcare access; multidisciplinary innovation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Computed Tomography Imaging for Clinical Diagnosis—2nd Edition

edited by Ibrahim Yel

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7834 | Submission Open

Keywords: computed tomography imaging; clinical diagnosis; dual-energy CT; photon-counting CT; image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances and Challenges in Gastrointestinal Endoscopy

edited by

Toshiro Iizuka

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7514 | Submission Open

Keywords: diagnosis at an early stage; endoscopy; precancerous lesion

(This special issue belongs to the Section Biomedical Optics)

Current Challenges and Perspectives of Ultrasound, 2nd Edition

edited by

Christoph Frank Dietrich

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7281 | Submission Open

Keywords: ultrasound; contrast-enhanced ultrasound (CEUS); endoscopic ultrasound; strain imaging; shear wave elastography; fusion imaging; endoscopic ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Issues on Kidney Diseases Diagnosis and Management 2025

edited by

Luis Yu

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7216 | Submission Open

Keywords: kidney diseases; renal involvement; AKI; CKD; glomerulopathies; diagnosis; treatment; dialysis; epidemiology; nephritic syndrome; nephrotic syndrome; biomarkers; urinalysis; oliguria; poliuria; electrolytes; acid-base balance

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Skin and Cutaneous Adnexal Tumors: Diagnosis and Management—2nd Edition

edited by

Andreas Manios

and

Dimitra Koumaki

submission deadline 31 Dec 2025 | 2 articles | Viewed by 6136 | Submission Open

Keywords: cutaneous adnexal tumors; follicular and sebaceous tumors; sweat gland tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Novel Methods and Devices for Monitoring and Diagnosing in Critical Care

edited by

Zhongheng Zhang

submission deadline 31 Dec 2025 | 6 articles | Viewed by 5991 | Submission Open

Keywords: hemodynamic monitoring; perfusion; heart-lung interactions; novel biomarkers; machine learning; ultrasound; therapeutic drug monitoring; wearable sensors

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Advances in the Diagnosis and Management of Breast Cancer

edited by

Fulvio Borella

and

Isabella Castellano

submission deadline 31 Dec 2025 | 3 articles | Viewed by 5456 | Submission Open

Keywords: prognostic and predictive factors; breast carcinoma; phylloid tumor; immunohistochemistry; diagnosis; breast cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Nephrology: Diagnosis and Management

edited by Elio Antonucci

submission deadline 31 Dec 2025 | 2 articles | Viewed by 5342 | Submission Open

Keywords: kidney disease; nephropathy; diagnosis management; renal disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Diagnostic Tools in the Emergency Department (ED): A Possible Help to Avoid Overcrowding

edited by Jacopo M. Legramante

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4569 | Submission Open

Keywords: critical care; emergency medicine; diagnostics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 301-350 on page 7 of 14.

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