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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 30 Sep 2025 | Viewed by 221 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in Cardiac MRI

edited by

Magalie Viallon

submission deadline 30 Sep 2025 | Viewed by 199 | Submission Open

Keywords: diagnosis; cardiac MRI; prognosis; patient care; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Sleep Disorders Using Machine Learning Approaches, 2nd Edition

edited by

Alaa Sheta

, Shyam Subramanian and

Salim R. Surani

submission deadline 30 Sep 2025 | Viewed by 192 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; sleep disorders; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Optical Coherence Tomography in Non-Invasive Diagnostic Imaging

edited by

Carmen Cantisani

and

Sandra Schuh

submission deadline 30 Sep 2025 | 1 articles | Viewed by 172 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; optical coherence tomography; non-invasive diagnostic imaging

(This special issue belongs to the Section Biomedical Optics)

Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis

edited by

Steven L. Fernandes

submission deadline 30 Sep 2025 | Viewed by 138 | Submission Open

Keywords: diagnosis; prognosis; tumor/cancer; deep learning; multimodal large language models

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition

edited by

Silvia Martu

Liliana-Georgeta Foia

and

Maria Alexandra Mârțu

submission deadline 30 Sep 2025 | Viewed by 136 | Submission Open

Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Lung Imaging: Highlights of Recent Research and Clinical Applications

edited by

Stefano Palmucci

submission deadline 30 Sep 2025 | Viewed by 134 | Submission Open

Keywords: diagnosis; prognosis; lung imaging; markers; clinical practice and patient care

(This special issue belongs to the Section Medical Imaging and Theranostics)

Applications of Electrodiagnosis in Neuromuscular Diseases

edited by

Donggyu Lee

submission deadline 30 Sep 2025 | Viewed by 133 | Submission Open

Keywords: electrodiagnosis; neuromuscular diseases; EMG (electromyography); nerve conduction studies; electrical stimulation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Gynecological Diseases: Advancements and Challenges

edited by

Massimo Origoni

submission deadline 30 Sep 2025 | Viewed by 123 | Submission Open

Keywords: gynecology; diagnosis; new technologies; female; women diseases; new approaches; genital pathology; reproductive medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hot Topics in Modern and Personalized Pathology

edited by

Sergejs Isajevs

submission deadline 30 Sep 2025 | Viewed by 116 | Submission Open

Keywords: personalized diagnostics and tissue biomarkers; molecular pathology; digital pathology; oncological pathology; and rare cancer studies; tumor diagnostics and tumor biomarkers; immunohistochemistry; molecular and ultrastructural pathology; laboratory medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Translational Research Advances in the Diagnosis of Hematological Diseases

edited by

Robert S. Ohgami

submission deadline 30 Sep 2025 | Viewed by 113 | Submission Open

Keywords: hematologic diseases; genomic diagnostics; digital pathology; biomarker; laboratory diagnostics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Microbiome-Based Diagnostics for Oncological Diseases: Innovations and Clinical Applications

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 30 Sep 2025 | Viewed by 108 | Submission Open

Keywords: microbiome-based diagnostics; disease biomarkers; gut microbiota; cancer microbiome; metagenomics; multi-omics in diagnostics; machine learning in microbiome analysis; dysbiosis and disease; precision medicine; microbiome– host interactions

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Radiation Oncology

edited by Xianjin Dai

submission deadline 30 Sep 2025 | Viewed by 108 | Submission Open

Keywords: artificial intelligence in radiation therapy; deep learning-based auto-segmentation; AI-driven radiotherapy; treatment planning; adaptive radiation therapy with AI radiomics and machine learning for outcome prediction; multi-modal image analysis in radiotherapy; reinforcement learning for dose optimization uncertainty; quantification in AI for radiation oncology; trustworthy and explainable AI in cancer treatment; AI-integrated radiotherapy; workflow automation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Enhancements in Screening Pathways for Early Detection of Lung Cancer

edited by

Paolo Albino Ferrari

and

Antonio Maccio

submission deadline 30 Sep 2025 | Viewed by 98 | Submission Open

Keywords: lung cancer screening; early diagnosis; multidisciplinary pathways; liquid biopsy; exhaled breath condensate; molecular imaging; sub-lobar resection; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Diagnosis and Management of Breast Cancer

edited by Wing Lok Wendy Chan

submission deadline 30 Sep 2025 | Viewed by 94 | Submission Open

Keywords: breast cancer; diagnosis; treatment; personalized medicine; imaging techniques; immunotherapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Diagnosis of Hypertension

edited by Vasileios Kotsis

submission deadline 30 Sep 2025 | Viewed by 93 | Submission Open

Keywords: hypertension; diagnosis; biomarkers; digital health; early detection

(This special issue belongs to the Section Clinical Laboratory Medicine)

Cardiometabolic Disease: Diagnosis and Management

edited by Muhammad Shariq Usman

submission deadline 30 Sep 2025 | Viewed by 90 | Submission Open

Keywords: cardiometabolic disease; diagnosis; management; diabetes; obesity; personalized medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus

edited by

Elisabeth Kapaki

and

Efstratios-Stylianos Pyrgelis

submission deadline 30 Sep 2025 | Viewed by 89 | Submission Open

Keywords: idiopathic normal pressure hydrocephalus (iNPH); neurological disorder; ventricular enlargement; cerebrospinal fluid (CSF) dynamics; cognitive impairment; gait disturbance

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Role of Diagnostic Imaging in Musculoskeletal Pain

edited by Ian Young

submission deadline 30 Sep 2025 | Viewed by 88 | Submission Open

Keywords: diagnostic imaging; musculoskeletal pain; imaging techniques (or imaging modalities); diagnostic accuracy; clinical applications; pain management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Evaluation and Management of Developmental Disabilities

edited by

Meir Lotan

submission deadline 30 Sep 2025 | Viewed by 87 | Submission Open

Keywords: developmental disabilities; early intervention; diagnostic assessment; therapeutic strategies; neurodevelopmental disorders; personalized care; multidisciplinary approach; family-centered support

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathology and Molecular Diagnosis of Vascular Diseases

edited by

Francisco S. Lozano Sánchez

and María Begoña García-Cenador

submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open

Keywords: vascular pathology; molecular diagnostics; precision medicine; biomarkers; atherosclerosis; thrombosis; vascular imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Molecular Diagnosis and Medical Management of Cardiovascular Diseases

edited by

Yiqing Yang

submission deadline 30 Sep 2025 | Viewed by 67 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; coronary artery disease; arrhythmia; cardiomyopathy; essential hypertension; stroke; molecular genetics; epidemiology; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Nuclear Medicine and Molecular Imaging in Cancer Diagnosis, Therapy, and Treatment Assessment

edited by

Sara Harsini

submission deadline 30 Oct 2025 | 2 articles | Viewed by 1163 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET/CT; theranostics; cancer diagnosis; treatment monitoring

(This special issue belongs to the Section Medical Imaging and Theranostics)

Deep Learning and Multimodal Feature Fusion for Advanced Medical Imaging Diagnosis

edited by

Sarmad Maqsood

and

Rytis Maskeliūnas

submission deadline 30 Oct 2025 | Viewed by 167 | Submission Open

Keywords: deep learning; feature fusion; medical imaging; artificial intelligence in healthcare; diagnostic imaging; multimodal data integration; explainable AI; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning in Medical Imaging: Challenges and Opportunities

edited by Morten Bo Søndergaard Svendsen

submission deadline 30 Oct 2025 | Viewed by 165 | Submission Open

Keywords: deep learning; artificial intelligence; medical imaging; endoscopy; image segmentation; medical image processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning in Medical Image Segmentation and Diagnosis

edited by Rahib Abiyev

submission deadline 31 Oct 2025 | 11 articles | Viewed by 20043 | Submission Open

Keywords: deep learning in medical diagnosis; medical imaging and deep learning; data mining and deep learning; emerging deep learning techniques and diagnosis; deep learning for the classification of lesions and disease; deep learning for segmentation; denoising; and super resolution; deep learning for signal analysis; learning mechanisms in deep neural networks; ensemble learning; stacked networks; medical informatics; computer-assisted diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Machine Learning for Computer-Aided Diagnosis in Biomedical Imaging—2nd Edition

edited by

Farhan Akram

submission deadline 31 Oct 2025 | 11 articles | Viewed by 18869 | Submission Open

Keywords: cancer diagnosis; medical images; electronic health records; machine learning; deep learning; artificial intelligence; explainable AI models; multi-modal analysis; federated learning; CAD systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Cardiovascular Diseases

edited by Fabrizio Guarracini and Cristina Giannattasio

submission deadline 31 Oct 2025 | 18 articles | Viewed by 15948 | Submission Open

Keywords: cardiovascular disease; risk stratification; preventive cardiology; hypertension; dyslipidaemias; heart failure management; interventional cardiology; coronary artery disease; arrythmias

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Assessment and Diagnosis of Cognitive Disorders

edited by

Elena Cecilia Rosca

submission deadline 31 Oct 2025 | 7 articles | Viewed by 15791 | Submission Open

Keywords: cognitive disorders; neurology; neuroimaging; biomarkers; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Ultrasound

edited by

Rute Santos

submission deadline 31 Oct 2025 | 11 articles | Viewed by 14284 | Submission Open

Keywords: quantitative ultrasound techniques; ultrasound tissue characterization; ultrasound-guided therapy or intervention; clinical applications of diagnostic ultrasound; ultrasound imaging processing; diagnostic ultrasound devices

(This special issue belongs to the Section Medical Imaging and Theranostics)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Oct 2025 | 8 articles | Viewed by 11292 | Submission Open

Keywords: diagnosis; precision medicine; predictive diagnostics; therapeutic strategies; biomarkers; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Prognosis of Heart Disease, 2nd Edition

edited by

Yuli Huang

submission deadline 31 Oct 2025 | 7 articles | Viewed by 11073 | Submission Open

Keywords: heart disease; coronary artery disease; arrhythmia; heart failure; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Sports Medicine

edited by

Luis Manuel Martínez Aranda

and

Jacobo Á. Rubio Arias

submission deadline 31 Oct 2025 | 4 articles | Viewed by 10142 | Submission Open

Keywords: diagnosis; sports injuries; injury frequency; ligaments; strain; tendon injuries; sport-related concussion; injury treatment; return to play; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis, Prognosis and Management of Hematologic Malignancies

edited by

Rossella Cacciola

Emma C. Cacciola

, Alessandra Romano and Alessandro Allegra

submission deadline 31 Oct 2025 | 6 articles | Viewed by 10084 | Submission Open

Keywords: leukemia; myeloproliferative neoplasms; myeloma; lymphoma

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Fetal Cardiology

edited by Maciej Słodki

submission deadline 31 Oct 2025 | 4 articles | Viewed by 9971 | Submission Open

Keywords: fetal cardiology; echocardiography; medical imaging; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Vasculitis

edited by

Alicia Rodríguez-Pla

submission deadline 31 Oct 2025 | 7 articles | Viewed by 9842 | Submission Open

Keywords: vasculitis; advances; updates; management; treatment; therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endoscopy in Diagnosis of Gastrointestinal Disorders—2nd Edition

edited by

Miguel Mascarenhas

submission deadline 31 Oct 2025 | 8 articles | Viewed by 8509 | Submission Open

Keywords: endoscopy; gastroenterology; coloproctology; digestive healthcare; artificial intelligence; digestive oncology; colonoscopy; capsule endoscopy; upper endoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Head and Neck Disease

edited by

Cristiana Lo Nigro

submission deadline 31 Oct 2025 | 7 articles | Viewed by 7806 | Submission Open

Keywords: head and neck disease; oral and maxillofacial disease; throat cancer; thyroid disease; otolaryngology tumor

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis of Skin Disease

edited by

Gerardo Cazzato

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7635 | Submission Open

Keywords: dermatology; dermatopathology; skin diseases; neoplastic diseases; inflammatory dermatopathology; CTCL; melanoma; squamous cell carcinoma; basal cell carcinoma; infectious diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Gynecological Oncology

edited by

Elena Bernad

and

Marius L. Craina

submission deadline 31 Oct 2025 | 6 articles | Viewed by 7258 | Submission Open

Keywords: female genital neoplasms; breast neoplasms; screening; diagnosis; treatment; surgery; medical oncology; psycho-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Thyroid Disorders

edited by Vladan Zivaljevic

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7007 | Submission Open

Keywords: thyroid disease management; diagnosis of thyroid disease; novel procedures; thyroid disorders; thyroid cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Applications and Potential of Magnetic Resonance Spectroscopy

edited by Jimin Ren

submission deadline 31 Oct 2025 | 4 articles | Viewed by 6958 | Submission Open

Keywords: magnetic resonance spectroscopy; metabolite; lipids and phospholipids; brain; skeletal muscle

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—2nd Edition

edited by

Andre Luiz Ferreira Costa

Kaan Orhan

and

Sérgio Lúcio Pereira de Castro Lopes

submission deadline 31 Oct 2025 | 5 articles | Viewed by 6295 | Submission Open

Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Thyroid Cancer

edited by

Kwangsoon Kim

submission deadline 31 Oct 2025 | 4 articles | Viewed by 6201 | Submission Open

Keywords: thyroid cancer; diagnosis; surgery; recurrence; theranostics; prognosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Treatment of Pediatric Emergencies—2nd Edition

edited by

Katerina Kambouri

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5910 | Submission Open

Keywords: pediatric emergency; diagnosis; pathology; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Optical Coherence Tomography in Diagnosis of Ophthalmology Disease

edited by Ninel Z Gregori and Lisa C. Olmos de Koo

submission deadline 31 Oct 2025 | 7 articles | Viewed by 5601 | Submission Open

Keywords: adaptive optics; multimodal imaging; optical coherence tomography; retinal diseases; spectral-domain optical coherence tomography; swept-source optical copherence tomography

(This special issue belongs to the Section Biomedical Optics)

Novel Technologies in Orthopedic Surgery: Diagnosis and Management

edited by Giuseppe Salvatore

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5429 | Submission Open

Keywords: orthopedic surgery; orthopedic diagnosis; orthopedics; computer navigation and augmented reality; robotics; digital templating; 3D Printing; artificial intelligence; machine learning; deep learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pediatric Gastrointestinal Pathology

edited by Juan Putra

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4909 | Submission Open

Keywords: inflammatory bowel disease; crohn disease; celiac disease; ulcerative colitis; vascular anomalies; eosinophilic esophagitis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2025

edited by

Paweł Gać

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4298 | Submission Open

Keywords: cardiovascular medicine; risk factors; heart and vascular biology; imaging diagnostics; electrocardiogram; biochemistry; toxicology; experimental medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Generative AI and Deep Learning in Medical Diagnostics

edited by

Steven L. Fernandes

submission deadline 31 Oct 2025 | 1 articles | Viewed by 4004 | Submission Open

Keywords: generative AI; medical diagnostics; medical imaging processing and analysis; deep learning; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

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