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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Application of Neuroimaging Biomarkers in the Diagnosis and Treatment of Mental Diseases, 2nd Edition

edited by Deborah A. Yurgelun-Todd, Douglas Kondo, Nicolas A Nunez, Perry Franklin Renshaw and Dost Öngür

submission deadline 25 Aug 2025 | 1 articles | Viewed by 6718 | Submission Open

Keywords: neuroimaging; biomarkers; 1H-MRS; 31P-MRS; brain spectroscopy; mood disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Perspectives in Forensic Diagnosis

edited by

Stavroula A. Papadodima

and

Laurent Martrille

submission deadline 31 Aug 2025 | 17 articles | Viewed by 37396 | Submission Open

Keywords: abuse; alcohol; autopsy; ballistics; brain injury; cause of death; drug-facilitated sexual assault; drugs; forensic anthropology; forensic clinical examination; forensic engineering; forensic entomology; forensic microbiology; forensic odontology; Forensic pathology; genetics; histopathology; identification of the body; molecular biology; multidisciplinary approach; post mortem interval; post-mortem biochemical analysis; postmortem CT; postmortem immunohistochemistry; postmortem MRI; rape; reconstruction of trauma; sepsis; toxicology; virtopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Abdominal Diseases: Diagnosis, Treatment and Management

edited by

Bogdan Socea

submission deadline 31 Aug 2025 | 13 articles | Viewed by 25904 | Submission Open

Keywords: abdominal diseases; abdominal surgery; diagnosis; image-guided surgery/treatment; minimally invasive techniques; laparoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Musculoskeletal and Neuropathic Pain in COVID-19: Diagnosis and Management Challenge

edited by

César Fernández-de-las-Peñas

and

Lidiane Lima Florencio

submission deadline 31 Aug 2025 | 4 articles | Viewed by 20392 | Submission Open

Keywords: COVID-19; long-COVID; pain; musculoskeletal; neuropathic; sensitization; mechanism

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Image Quality Assessment Methods in Radiography, Computed Tomography and Magnetic Resonance

edited by

Rafał Obuchowicz

Adam Piórkowski

and

Michał Strzelecki

submission deadline 31 Aug 2025 | 9 articles | Viewed by 17737 | Submission Open

Keywords: CR; MRI; CT; image quality; preprocessing and postprocessing; texture analysis; artificial intelligence; quality control

(This special issue belongs to the Section Medical Imaging and Theranostics)

Grand Challenges in the Diagnosis and Management of Cardiovascular and Cerebrovascular Diseases

edited by

Sonu M. M. Bhaskar

submission deadline 31 Aug 2025 | 10 articles | Viewed by 16011 | Submission Open

Keywords: cardiovascular diseases; cerebrovascular diseases; diagnosis; management; imaging; biomarkers; artificial intelligence; therapeutic strategies; pharmacology; surgery; rehabilitation; multidisciplinary care

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advanced Brain Tumor Imaging

edited by

Giorgio Treglia

and Barbara Muoio

submission deadline 31 Aug 2025 | 7 articles | Viewed by 15190 | Submission Open

Keywords: brain tumors; gliomas; brain metastases; meningioma; neuroimaging; magnetic resonance; PET; MRI

(This special issue belongs to the Section Medical Imaging and Theranostics)

EEG Analysis in Diagnostics

edited by

Jae-Ho Han

submission deadline 31 Aug 2025 | 9 articles | Viewed by 12694 | Submission Open

Keywords: advanced EEG Techniques; the characterization of EEG signal patterns; the identification of EEG signal abnormalities; functional connectivity analysis in EEG; sleep studies based on EEG; EEG in epilepsy diagnosis and monitoring; neurofeedback and EEG in cognitive enhancement; event-related potentials in clinical EEG; understanding pathophysiology via EEG

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pulmonary and Critical Care Medicine: Diagnosis and Management

edited by

Te-Chun Shen

submission deadline 31 Aug 2025 | 6 articles | Viewed by 11523 | Submission Open

Keywords: COPD; asthma; interstitial lung disease; lung cancer; pneumonia (respiratory infection; pulmonary infection); obstructive sleep apnea; respiratory failure; acute respiratory distress syndrome

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Information-Driven Computer-Aided Diagnosis and Decision Support System

edited by Wen-Shan Jian and

Shuo-Chen Chien

submission deadline 31 Aug 2025 | 5 articles | Viewed by 8713 | Submission Open

Keywords: computer-aided diagnosis; decision support systems; machine learning in healthcare; artificial intelligence in medicine; medical data analytics; predictive modeling; clinical decision-making; healthcare informatics; diagnostic accuracy; patient outcomes

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Application of Artificial Intelligence in Gastrointestinal Disease

edited by Kai Zhao

submission deadline 31 Aug 2025 | 6 articles | Viewed by 8444 | Submission Open

Keywords: artificial intelligence; machine learning; gastrointestinal disease

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Acute Kidney Injury and Chronic Kidney Disease: From Pathogenesis to Diagnostics

edited by

Dimitris Kounatidis

and

Natalia G. Vallianou

submission deadline 31 Aug 2025 | 3 articles | Viewed by 8380 | Submission Open

Keywords: acute kidney injury (AKI); chronic kidney disease (CKD); pathogenesis; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Dental Medicine and Surgery

edited by

José María Martinez-Gonzalez

submission deadline 31 Aug 2025 | 5 articles | Viewed by 7667 | Submission Open

Keywords: oral surgery; oral medicine; implant dentistry; gerodontology; pharmacological treatments; bone regeneration; oral rehabilitation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Sepsis at the Crossroads: Innovations in Critical Care Management, Diagnostic Tools, and Treatment Paradigms

edited by

Paolo Formenti

submission deadline 31 Aug 2025 | 3 articles | Viewed by 6092 | Submission Open

Keywords: sepsis and clinical recognition; septic shock; SOFA and organ dysfunction; acute kidney injury; renal replacement therapy; new biomarkers; new therapeutic options

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

New Possibilities for Digital Diagnosis and Planning in Dentistry

edited by

Rodolfo Reda

submission deadline 31 Aug 2025 | 4 articles | Viewed by 5827 | Submission Open

Keywords: dental imaging; CBCT; MRI; scan; digital impression; digital plan; digital guide; CAD-CAM; manufacturing

(This special issue belongs to the Section Medical Imaging and Theranostics)

Neurological Diseases: Biomarkers, Diagnosis and Prognosis

edited by

Theodosis Kalamatianos

submission deadline 31 Aug 2025 | 7 articles | Viewed by 5600 | Submission Open

Keywords: biomarkers; neurological diseases; multiple sclerosis; traumatic brain injury; peripheral neuropathies; COVID-19 neurological-associated damage; diagnosis; prognosis.

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Developments and Future Trends in Thoracic Imaging

edited by Ioana Andreea Gheonea

submission deadline 31 Aug 2025 | 3 articles | Viewed by 5582 | Submission Open

Keywords: X-ray; computed tomography; magnetic resonance imaging; ultra-low-dose CT; photon-counting CT; oncology; artificial intelligence; emergency radiology; thoracic trauma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Endometriosis

edited by

Simone Ferrero

submission deadline 31 Aug 2025 | 2 articles | Viewed by 5149 | Submission Open

Keywords: endometriosis; diagnosis; ultrasonography; recurrence; prognosis; symptoms; laparoscopy; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Applications of Artificial Intelligence in Gastrointestinal Diseases

edited by Dimitra D. Dionysiou and Ioannis Gallos

submission deadline 31 Aug 2025 | 3 articles | Viewed by 4811 | Submission Open

Keywords: gastrointestinal disease; artificial intelligence; biomarkers; screening/diagnosis; personalized medicine; treatment outcome; pathogenesis; risk management

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Perspectives in Ophthalmic Imaging

edited by

Ratheesh Kumar Meleppat

submission deadline 31 Aug 2025 | 4 articles | Viewed by 4803 | Submission Open

Keywords: optical coherence tomography; retinal imaging; ophthalmic imaging; OCT; diagnosis of eye diseases

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Machine Learning in Disease Screening, Diagnosis and Prognosis

edited by Dee Pei

submission deadline 31 Aug 2025 | 6 articles | Viewed by 4682 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Advances in Hyperspectral and Multispectral Imaging for Diseases Diagnosis

edited by

Arvind Mukundan

submission deadline 31 Aug 2025 | 3 articles | Viewed by 4657 | Submission Open

Keywords: spectral imaging; hyperspectral imaging (HSI); multispectral imaging (MSI); medical diagnostics; disease detection; clinical applications; imaging technology; early diagnosis; personalized medicine; diagnostic pathways; healthcare innovations; biomedical imaging

(This special issue belongs to the Section Biomedical Optics)

New Perspectives in Cardiac Imaging

edited by

George Koulaouzidis

submission deadline 31 Aug 2025 | 4 articles | Viewed by 4206 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiac magnetic resonance imaging; computed tomography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Future Challenges for Lung and Liver Ultrasound

edited by Chiara De Molo

submission deadline 31 Aug 2025 | 2 articles | Viewed by 4128 | Submission Open

Keywords: lung ultrasound; liver ultrasound; pulmonary ultrasound; diagnosis; sonography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Expanding Horizons in Fascial Diagnostics and Interventions

edited by

Stanley K. H. Lam

and Bradley Dean Fullerton

submission deadline 31 Aug 2025 | 1 articles | Viewed by 4071 | Submission Open

Keywords: ultrasound imaging; fascial pathologies; musculoskeletal function; fascial disorders; ultrasound-guided interventions; musculoskeletal care

(This special issue belongs to the Section Medical Imaging and Theranostics)

Symptoms, Diagnosis, Prognosis and Management of Long COVID or Post-COVID Conditions, 2nd Edition

edited by

Tim Duong

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3801 | Submission Open

Keywords: long COVID; SARS-CoV-2; COVID-19 sequela; post-acute sequelae of COVID-19 (PASC); COVID-19 symptoms; multiorgan failure; diabetes; hypertension; shortness of breath; symptoms; diagnosis; prognosis; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Autopsy for Medical Diagnostics: 3rd Edition

edited by

Giulia Ottaviani

and

Simone G. Ramos

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3548 | Submission Open

Keywords: autopsy; post-mortem investigation; cardiovascular pathology; sudden cardiac death; sudden unexpected death; perinatal autopsy; molecular autopsy; virtual autopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Hearing Loss and Deafness: Identification, Management, Prevention, and Rehabilitation

edited by Peter J. Kullar and Jameel Muzaffar

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3444 | Submission Open

Keywords: hearing loss; presbycusis; cochlear implants; hearing implants; hearing aids; congenital hearing loss; sudden sensorineural hearing loss

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Insights into Pediatric Genetics

edited by

Chunglin Lee

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3313 | Submission Open

Keywords: pediatric genetics; genetic sequencing; rare disorders; genetic diagnosis; precision medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Pathology and Diagnosis of Hematology

edited by

Elizabeth Soilleux

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3290 | Submission Open

Keywords: medical diagnosis; pathology; hematology; leukemia; lymphoma; myeloproliferative disorders; thrombotic microangiopathies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in the Diagnosis and Treatment of Inflammatory Bowel Diseases

edited by Thomas Klag

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3256 | Submission Open

Keywords: chronic inflammatory bowel diseases (IBD); Crohn's disease (CD); ulcerative colitis (UC); therapy monitoring; extraintestinal manifestations (EIMs); quality of life; artificial intelligence (AI); personalized medicine; personalized medicine; endoscopic advancements

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Immune-Mediated Diseases: Diagnosis and Management

edited by

Marcos López Hoyos

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2942 | Submission Open

Keywords: immune-mediated inflammatory disease; biomarker; companion diagnostics; cytokines; immunoregulation; complement; autoantibodies; innate immunity; adaptive immunity; multiplexing; immunophenotype; mass cytometry; ELISPOT; single-cell RNA

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Use of Histopathological Image Analysis in Diagnostics

edited by

Elizabeth Soilleux

and

Florian Jaeckle

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2876 | Submission Open

Keywords: histopathological; diagnostics; artificial intelligence; algorithms; image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advancements in the Diagnostics and Management of Musculoskeletal Diseases

edited by

Alessandro de Sire

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2405 | Submission Open

Keywords: musculoskeletal system; joint; orthopedics; traumatology; rehabilitation; radiology; fracture; muscle; connective tissues; regenerative medicine; tissue engineering

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Advances in Cardiovascular Risk Prediction

edited by Ming-Shyan Lin

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2399 | Submission Open

Keywords: cardiovascular diseases; risk prediction; biomarker; machine learning

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in the Diagnosis and Management of Respiratory Diseases

edited by Elio Antonucci

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2372 | Submission Open

Keywords: respiratory disease diagnosis; advanced diagnostic techniques; respiratory management strategies; therapeutic innovations; pulmonary pathophysiology; chronic obstructive pulmonary disease (COPD); asthma management; interstitial lung diseases; respiratory infection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Deep Learning in Biomedical Signal Analysis

edited by

Takahiro Emoto

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2224 | Submission Open

Keywords: deep learning; biomedical signal processing; pattern recognition; disease diagnosis; feature extraction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Multiple Myeloma Imaging in 2025

edited by

Majid Chalian

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1961 | Submission Open

Keywords: PET/CT; MRI; multiple myeloma; diagnosis; multiparametric imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Anesthesia and Pain Medicine

edited by Jamal Hasoon

submission deadline 31 Aug 2025 | 4 articles | Viewed by 1890 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Liquid Biopsy for the Diagnosis of Breast Cancer

edited by

Chihwan David Cha

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1840 | Submission Open

Keywords: breast cancer; diagnosis; metastasis; ctDNA; liquid biopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advanced Role of Endoscopic Ultrasound in Clinical Medicine

edited by

Germana De Nucci

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1674 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic imaging; fine needle aspiration (FNA); contrast-enhanced EUS; elastography techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence Approaches for Medical Diagnostics in the USA

edited by

Jinzhong Yang

and Yao Zhao

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1668 | Submission Open

Keywords: artificial intelligence; medical image segmentation; image registration; image quality enhancement; image artifact reduction; radiomics; image reconstruction; deep learning in diagnostics; AI-driven medical Imaging; diagnostic accuracy; diagnostic imaging innovations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Applications of Optical Coherence Tomography and Optical Coherence Tomography Angiography in Ophthalmology

edited by

Daniela Bacherini

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1621 | Submission Open

Keywords: OCT; OCTA; ophthalmology; diagnostics; clinical applications

(This special issue belongs to the Section Biomedical Optics)

Advances in Imaging Diagnosis of Dermatology

edited by Linda Tognetti

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1536 | Submission Open

Keywords: high-resolution imaging; non-invasive diagnosis; LC-OCT; RCM; OCT; US

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging and Diagnosis in Neurosurgery

edited by Giulio Anichini

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1451 | Submission Open

Keywords: MRI sequences; magnetic electroencephalography; endovascular neurosurgery; fluorescence-guided surgery; spectroscopic technologies (e.g.; Raman; confocal; and hyperspectral); mü ller matrix polarization; intraoperative neuromonitoring; two/three-dimensional endoscopes; exoscopes; artificial intelligence; laboratory diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Infectious Disease Diagnosis Technologies

edited by

Dakai Liu

and Fermina Maria Mazzella

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1365 | Submission Open

Keywords: molecular diagnosis; biomarkers; microbial culture and identification; high-throughput sequencing; infectious diseases; artificial intelligence; digital image; radiological imaging; point-of-care testing

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Management of Coronary Heart Disease

edited by Luciano Candilio

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1283 | Submission Open

Keywords: coronary heart disease; coronary revascularization; coronary artery disease; ischemic heart disease; atherosclerosis; cardiovascular disease; non-invasive coronary diagnostic tests

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emergency Medicine: Diagnostic Insights

edited by Ancor Sanz-Garcia and Raúl López-Izquierdo

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1230 | Submission Open

Keywords: diagnostic tools; point-of-care testing; prehospital; emergency medicine; rapid and accurate diagnosis; imaging modalities; biomarkers; AI-driven algorithms

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Diagnostic Cytology

edited by Varsha Manucha

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1218 | Submission Open

Keywords: cytological diagnosis; fine-needle aspiration; rapid onsite evaluation (ROSE); ancillary testing; immunohistochemistry; fluorescence in situ hybridization (FISH)

(This special issue belongs to the Section Clinical Laboratory Medicine)

Imaging of the Future: From the Standardisation of Diagnostic Processes to Artificial Intelligence

edited by

Emanuele David

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1211 | Submission Open

Keywords: artificial intellicence; technologies; ultrasound; MRI; CT; angiography; mammography

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

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