Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Thyroid Disorders: New Clinical Diagnosis and Management submission deadline 15 May 2026 | Viewed by 347 | Submission Open
Keywords: thyroid disorders; clinical diagnosis; ultrasound; elastography; thyroid cancer; thyroiditis; hyperthyroidism; hypothyroidism; advanced imaging
Advances in Nephrology submission deadline 30 May 2026 | 9 articles | Viewed by 48946 | Submission Open
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Diagnostic and Therapeutic Strategies for Infectious Diseases
edited by
submission deadline 31 May 2026 | 8 articles | Viewed by 23786 | Submission Open
Keywords: infectious diseases; diagnostic advancements; therapeutic strategies; antimicrobial resistance; molecular diagnostics; clinical management; emerging pathogens; precision medicine
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Diagnosis and Management of Ophthalmic Disorders
edited by Assaf Kratz
submission deadline 31 May 2026 | 12 articles | Viewed by 15376 | Submission Open
Keywords: ocular diseases; early diagnosis; advanced imaging; glaucoma; age-related macular degeneration; diabetic retinopathy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Medical Imaging in Diagnosis, Prevention and Rehabilitation of Musculoskeletal Injuries
edited by , W. Catherine Cheung and Suguna Pappu
submission deadline 31 May 2026 | 4 articles | Viewed by 10538 | Submission Open
Keywords: fitting of prostheses and exoskeletons; force-based manipulations; medical imaging (e.g.; MRI; CT; ultrasound elastography); musculoskeletal pain (low-back pain and non-specific causes of chronic pain); myofascial pain syndrome; sports training; surgical scar and postoperative management; thermal and non-thermal modalities
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advanced Diagnostic Approaches in Cardiovascular Diseases: From Imaging to Biomarkers submission deadline 31 May 2026 | 11 articles | Viewed by 10236 | Submission Open
Keywords: medical diagnosis; cardiovascular diseases; imaging; biomarkers; AI-driven analytics
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Liquid Biopsy: Cancer Diagnostic Biomarkers of the Future
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 9792 | Submission Open
Keywords: liquid biopsy; circulating tumor cells (CTCs); ctDNA testing; exosomes; blood analytes
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
DNA Sequencing of Infectious Diseases submission deadline 31 May 2026 | 4 articles | Viewed by 8826 | Submission Open
Keywords: DNA sequencing; infectious disease; diagnostics; screening; whole-genome sequencing; targeted amplicon sequencing
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Endoscopic Diagnostics for Pancreatobiliary Disorders 2025
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 8092 | Submission Open
Keywords: endoscopic ultrasonography; endoscopic retrograde cholangiopancreatography; EUS– FNA; SPACE; pancreatic cancer; bile duct caner; gallbladder cancer
(This special issue belongs to the Section Biomedical Optics)
Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition
edited by Costantino Ricci
submission deadline 31 May 2026 | 5 articles | Viewed by 8001 | Submission Open
Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Oral and Maxillofacial Imaging submission deadline 31 May 2026 | 6 articles | Viewed by 7509 | Submission Open
Keywords: technological advancements; diagnostic imaging; treatment planning; clinical applications; oral and maxillofacial surgery; radiology
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Diagnosis of Digestive Diseases
edited by Noriaki Manabe
submission deadline 31 May 2026 | 4 articles | Viewed by 7306 | Submission Open
Keywords: diagnosis of gastrointestinal disease; functional gastrointestinal disorders; organic diseases; personalized medicine; physiological function evaluation
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Emergency Medicine: Diagnostic Insights
edited by Ancor Sanz-Garcia and Raúl López-Izquierdo
submission deadline 31 May 2026 | 4 articles | Viewed by 7245 | Submission Open
Keywords: diagnostic tools; point-of-care testing; prehospital; emergency medicine; rapid and accurate diagnosis; imaging modalities; biomarkers; AI-driven algorithms
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management
edited by Ombretta Martinelli and
submission deadline 31 May 2026 | 7 articles | Viewed by 7163 | Submission Open
Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases
edited by and Xavier Iriart
submission deadline 31 May 2026 | 4 articles | Viewed by 6409 | Submission Open
Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Musculoskeletal Disorders: Diagnosis, Management, and Rehabilitation, 2nd Edition
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 5367 | Submission Open
Keywords: musculoskeletal disorders; pain; disability; diagnosis; interventions; rehabilitation strategies; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Artificial Intelligence Approaches for Medical Diagnostics in the USA
edited by and Yao Zhao
submission deadline 31 May 2026 | 4 articles | Viewed by 5181 | Submission Open
Keywords: artificial intelligence; medical image segmentation; image registration; image quality enhancement; image artifact reduction; radiomics; image reconstruction; deep learning in diagnostics; AI-driven medical Imaging; diagnostic accuracy; diagnostic imaging innovations
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Histopathology in Cancer Diagnosis and Prognosis—2nd Edition
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 4993 | Submission Open
Keywords: cancer; precision medicine; histopathology; diagnosis; prognostic/predictive markers
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Application of Ultrasound Imaging in Clinical Diagnosis
edited by
submission deadline 31 May 2026 | 5 articles | Viewed by 4304 | Submission Open
Keywords: diagnostic ultrasound imaging and systems; doppler ultrasound techniques and applications; elastography for tissue characterization; contrast-enhanced ultrasound (CEUS); artificial intelligence in diagnostic ultrasound; point-of-care ultrasound (POCUS); ultrasound-guided interventions
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in the Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus submission deadline 31 May 2026 | 1 articles | Viewed by 4065 | Submission Open
Keywords: idiopathic normal pressure hydrocephalus (iNPH); neurological disorder; ventricular enlargement; cerebrospinal fluid (CSF) dynamics; cognitive impairment; gait disturbance
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Medical Imaging Diagnosis of Oral and Maxillofacial Diseases
edited by , and Erwin Berkhout
submission deadline 31 May 2026 | 4 articles | Viewed by 3848 | Submission Open
Keywords: oral radiology; digital dentistry; dental imaging; diagnosis; treatment planning
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advanced Diagnosis and Integrated Management of Bone and Soft Tissue Tumors
edited by Tiao Lin
submission deadline 31 May 2026 | 6 articles | Viewed by 3777 | Submission Open
Keywords: musculoskeletal neoplasms; diagnostic imaging; molecular pathology; multidisciplinary treatment; personalized medicine; translational research; multidisciplinary collaboration
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Applications of CT and MRI
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 3748 | Submission Open
Keywords: CT; MRI; diagnosis; prognosis; oncology; neurology
(This special issue belongs to the Section Medical Imaging and Theranostics)
Cardiometabolic Disease: Diagnosis and Management
edited by Muhammad Shariq Usman
submission deadline 31 May 2026 | 1 articles | Viewed by 3584 | Submission Open
Keywords: cardiometabolic disease; diagnosis; management; diabetes; obesity; personalized medicine
(This special issue belongs to the Section Clinical Laboratory Medicine)
Collaborative Robotics and Total Laboratory Automation in Clinical Diagnostics
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 3557 | Submission Open
Keywords: collaborative robotics; total laboratory automation (TLA); diagnostic medicine; clinical validation  ; robotic liquid handling  ; digital pathology  ; clinical microbiology
(This special issue belongs to the Section Clinical Laboratory Medicine)
Clinical Advances and Applications in Neuroradiology: 2nd Edition
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 3118 | Submission Open
Keywords: neuroradiology; advanced imaging; susceptibility-weighted imaging (SWI); diffusion tensor imaging (DTI); functional MRI (fMRI); CT perfusion; MR perfusion; MR spectroscopy; PET; molecular imaging; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in the Use of Artificial Intelligence for the Diagnosis and Management of Hand Conditions
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 3059 | Submission Open
Keywords: artificial intelligence; machine learning; hand conditions; preoperative diagnosis; postoperative prognosis; surgical outcomes; imaging techniques
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Medical Imaging: Innovations and Diagnostic Applications
edited by , Moumen Elmelegy, and
submission deadline 31 May 2026 | 3 articles | Viewed by 2978 | Submission Open
Keywords: medical imaging; artificial intelligence; disease diagnosis; radiomics
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
The Application of Large Language Models (LLMs) and Vision-Language Models (VLMs) in Healthcare submission deadline 31 May 2026 | 3 articles | Viewed by 2889 | Submission Open
Keywords: large language models (LLMs); vision-language models (VLMs); artificial intelligence in healthcare; natural language processing (NLP); clinical decision support systems; medical imaging analysis; multimodal learning; healthcare data analytics; patient-centered care; ethical AI in medicine
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
From Data to Decisions: Deep Learning in Clinical Diagnostics
edited by Jianfu Li
submission deadline 31 May 2026 | 1 articles | Viewed by 2752 | Submission Open
Keywords: deep learning; clinical diagnostics; medical AI; diagnostic accuracy; clinical decision support; medical imaging; biomarker discovery; healthcare implementation
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Precise Diagnosis, Classification, and Monitoring of Pulmonary Diseases submission deadline 31 May 2026 | 1 articles | Viewed by 2453 | Submission Open
Keywords: lung diseases; pulmonary diseases; imaging techniques; causal biological pathways; clinical biomarkers
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical and Laboratory Diagnosis of Inherited Metabolic Diseases in Children
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 2123 | Submission Open
Keywords: newborn screening; selective screening; inherited metabolic disease; biochemical diagnostics; biomarkers; molecular analysis; next-generation sequencing
(This special issue belongs to the Section Clinical Laboratory Medicine)
Emerging Predictive Biomarkers in Breast Cancer
edited by and Maria Vita Sanò
submission deadline 31 May 2026 | 1 articles | Viewed by 1933 | Submission Open
Keywords: breast cancer; HER2-positive; TNBC; ER+; HER2-negative; HER2-low; PD-L1; 18F-FES PET; hormonotherapy; immunotherapy; immune checkpoint inhibitors; liquid biopsy; circulating tumor cells; ctDNA; antibody drug conjugates; PARP inhibitors; CDK4/6 inhibitors; predictive biomarkers
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Diagnostic Options and Treatment Strategies for Neurological Disorders
edited by and Jenny Stritzelberger
submission deadline 31 May 2026 | 3 articles | Viewed by 1847 | Submission Open
Keywords: neuroscience; diagnostic tools; point-of-care testing; prehospital care; emergency medicine; rapid and accurate diagnosis; treatment strategies
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
New Advances in Diagnostic Bronchoscopy
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1783 | Submission Open
Keywords: diagnostic bronchoscopy; advanced imaging techniques; interventional bronchoscopy; minimally invasive techniques
(This special issue belongs to the Section Biomedical Optics)
Diagnostic Imaging in Ocular Surface
edited by and David Berkow
submission deadline 31 May 2026 | 3 articles | Viewed by 1666 | Submission Open
Keywords: ocular surface imaging; contact lens fitting; ultra-high-resolution oct; corneal topography; corneal tomography; scleral profilometry; wavefront aberrometry; in vivo confocal microscopy; artificial intelligence in eye imaging; meibomian gland imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Artificial Intelligence in Biomedical Signal and Imaging Processing submission deadline 31 May 2026 | 1 articles | Viewed by 1631 | Submission Open
Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Diagnosis and Management of Inflammatory Respiratory Diseases
edited by Kęstutis Malakauskas and
submission deadline 31 May 2026 | 1 articles | Viewed by 1529 | Submission Open
Keywords: asthma; chronic obstructive pulmonary disease; inflammatory respiratory diseases; inflammation; biomarkers; respiratory diagnostics; anti-inflammatory therapy
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in Inflammation and Infection Imaging: 2nd Edition
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 1515 | Submission Open
Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Diagnostic and Operative Hysteroscopy, 2nd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 1353 | Submission Open
Keywords: hysteroscopy; diagnosis; technique; malformation; uterus; endometrial; anomaly; minimally invasive; pathology
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Diagnosis and Treatment of Gynecological Infections
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1230 | Submission Open
Keywords: genital infections; vaginal microbiome; sexually transmitted infections; diagnostic microscopy; antibiotic resistance
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Ocular Surface Alterations in Eyelid Malpositions: Pathophysiology, Diagnostic Tools, and Therapeutic Approaches
edited by Massimiliano Serafino and
submission deadline 31 May 2026 | 1 articles | Viewed by 1217 | Submission Open
Keywords: lid malpositions and ocular surface disorders; dry eye syndrome; exposure keratopathy; tear film instability; anterior segment imaging; lid surgery outcomes
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Editorial Board Members' Collection Series: Molecular Diagnostics of Infectious Diseases, 2nd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 1202 | Submission Open
Keywords: molecular diagnostics; infectious diseases; microorganisms; virus detection; antibiotic resistance; bacterial strains
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Advances in the Diagnosis and Management of Autoimmune Rheumatic Diseases
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 891 | Submission Open
Keywords: autoimmune rheumatic diseases; biomarkers; precision medicine; targeted therapy; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in the Diagnosis and Management of Sports Injuries
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 867 | Submission Open
Keywords: sport injuries; sport traumatology; arthroscopy; surgery; joints
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Brain Radiation Necrosis: Emerging Insights in Pathophysiology, Diagnosis, and Management
edited by and Gokoulakrichenane Loganadane
submission deadline 31 May 2026 | 1 articles | Viewed by 837 | Submission Open
Keywords: brain radiation necrosis; radiation therapy; multimodal imaging; differential diagnosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Risk Factors, Incidence, and Outcome of Stroke
edited by Emir Veledar
submission deadline 31 May 2026 | 1 articles | Viewed by 745 | Submission Open
Keywords: stroke prevention; acute stroke management; post-acute stroke care; predictive modeling; risk stratification; neuroimaging; biomarkers; early detection; prognostic evaluation; diagnostic algorithms; cerebral infarction; intracranial hemorrhage; ischemic stroke subtypes
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Latest Advances in Ophthalmic Imaging: Second Edition submission deadline 31 May 2026 | 1 articles | Viewed by 708 | Submission Open
Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
Innovations in HIV Diagnostics and Monitoring
edited by Nuno Taveira
submission deadline 31 May 2026 | 1 articles | Viewed by 656 | Submission Open
Keywords: HIV disease; HIV diagnostics; HIV testing; HIV monitoring; point-of-care testing; next-generation sequencing; biomarkers
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Interdisciplinary Approaches to Improve Cardiovascular Outcomes
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 645 | Submission Open
Keywords: cardiovascular disease; prevention; risk factors; cardiovascular outcomes; interdisciplinarity; burden of disease
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
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