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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Trends in Ultrasound Imaging

edited by

Ştefan Cristian Vesa

and

Ingrid Andrada Vasilache

submission deadline 15 Feb 2026 | 1 articles | Viewed by 1089 | Submission Open

Keywords: ultrasound; imaging; diagnostics; artificial intelligence; elastography; contrast-enhanced ultrasound; radiomics; 3D ultrasound; point-of-care ultrasound; interventional imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Acute Kidney Injury and Chronic Kidney Disease: From Pathogenesis to Diagnostics

edited by

Dimitris Kounatidis

and

Natalia G. Vallianou

submission deadline 28 Feb 2026 | 3 articles | Viewed by 15624 | Submission Open

Keywords: acute kidney injury (AKI); chronic kidney disease (CKD); pathogenesis; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis of Oral and Maxillofacial Disease: 2nd Edition

edited by

Luís Eduardo Almeida

submission deadline 28 Feb 2026 | 8 articles | Viewed by 13029 | Submission Open

Keywords: maxillofacial disease; oral disease; biomarkers; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Echocardiography, 2nd Edition

edited by

Giulia Elena Mandoli

submission deadline 28 Feb 2026 | 8 articles | Viewed by 11915 | Submission Open

Keywords: standard echocardiography; speckle tracking echocardiography; strain; myocardial deformation; 3D echocardiography; valvular reconstruction; differential diagnosis; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Diagnostic and Interventional Radiology

edited by

Serena Carriero

submission deadline 28 Feb 2026 | 7 articles | Viewed by 11307 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; image-guided therapy; AI; minimally invasive procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Contemporary Issues in Maternal-Fetal Medicine

edited by

Themistoklis Dagklis

and

Ioannis Tsakiridis

submission deadline 28 Feb 2026 | 5 articles | Viewed by 11285 | Submission Open

Keywords: obstetrics; high-risk pregnancy; maternal medicine; fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Maternal–Fetal and Neonatal Diagnostics

edited by Elisa Bevilacqua

submission deadline 28 Feb 2026 | 3 articles | Viewed by 10520 | Submission Open

Keywords: high risk pregnancy; twin pregnancy; maternal– fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Molecular Pathology and Imaging for Precision Diagnosis and Treatment of Tumors

edited by

Maurizio Martini

submission deadline 28 Feb 2026 | 7 articles | Viewed by 10032 | Submission Open

Keywords: molecular pathology; molecular imaging; precision oncology; biomarkers; digital pathology; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management in Otolaryngology 2026

edited by

Rong-San Jiang

submission deadline 28 Feb 2026 | 4 articles | Viewed by 9985 | Submission Open

Keywords: ear; diagnosis; head and neck; management; nose; otolaryngology; throat

(This special issue belongs to the Section Medical Imaging and Theranostics)

Explainable Machine Learning in Clinical Diagnostics

edited by

Kai-Chih Pai

submission deadline 28 Feb 2026 | 6 articles | Viewed by 8525 | Submission Open

Keywords: interpretable machine learning (IML); explainable machine learning; clinical medicine; knowledge integration; global/local explanations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Liquid Chromatography–Mass Spectrometry (LC-MS) in the Clinical Laboratory

edited by

Siddabasave Gowda B. Gowda

submission deadline 28 Feb 2026 | 5 articles | Viewed by 8470 | Submission Open

Keywords: LC-MS; clinical diagnostics; biomarker discovery; metabolomics; lipidomics; clinical samples; method validation; precision medicine; analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Colorectal Lesions

edited by Andrei Chitul

submission deadline 28 Feb 2026 | 4 articles | Viewed by 8191 | Submission Open

Keywords: colorectal lesions; diagnostic modalities; imaging techniques; machine learning; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Applications of Artificial Intelligence in Gastrointestinal Diseases

edited by Dimitra D. Dionysiou and Ioannis Gallos

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7883 | Submission Open

Keywords: gastrointestinal disease; artificial intelligence; biomarkers; screening/diagnosis; personalized medicine; treatment outcome; pathogenesis; risk management

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Computed Tomography Imaging in Medical Diagnosis, 2nd Edition

edited by

Fabio Sandomenico

submission deadline 28 Feb 2026 | 4 articles | Viewed by 7297 | Submission Open

Keywords: computed tomography; medical diagnosis; imaging; internal organs; bones; soft tissue; blood vessels

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI in Dermatology

edited by Jonathan Shapiro

submission deadline 28 Feb 2026 | 4 articles | Viewed by 7156 | Submission Open

Keywords: teledermatology; artificial intelligence; AI algorithms; natural language processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Next-Generation Diagnostic Strategies: Bridging Health Sciences and Laboratory Medicine

edited by

Syed M. Shahid

submission deadline 28 Feb 2026 | 1 articles | Viewed by 6593 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; prevision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advancements in the Diagnosis and Management of Liver Disease and Liver Transplantation

edited by Ioana Gabriela Lupescu

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6033 | Submission Open

Keywords: focal and diffuse liver pathology; liver transplantation; MPMRI; MDCT; advanced imaging techniques; specific liver contrast material; imaging biomarkers; interventional radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Technological Advances in Oral and Maxillofacial Surgery for Diagnosis

edited by

Maria Giulia Cristofaro

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5751 | Submission Open

Keywords: oral and maxillofacial surgery; oral cancers; maxillofacial trauma; surgical and informatics technology; intraoperative navigation; robotic surgery; oral and maxillofacial surgery reconstruction; nanotechnologies; DNA sequencing

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging of the Future: From the Standardisation of Diagnostic Processes to Artificial Intelligence

edited by

Emanuele David

submission deadline 28 Feb 2026 | 1 articles | Viewed by 5655 | Submission Open

Keywords: artificial intellicence; technologies; ultrasound; MRI; CT; angiography; mammography

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Perspectives and Gaps in the Diagnosis and Management of Rheumatic Diseases

edited by Vikas Majithia

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5545 | Submission Open

Keywords: rheumatology; rheumatic diseases; inflammatory connective tissue diseases; rheumatoid arthritis; systemic lupus erythematosus; vasculitis; spondyloarthritis; scleroderma; osteoarthritis; current perspective; diagnosis; treatment; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Thyroid Cancer: Types, Symptoms, Diagnosis and Management

edited by

Mara Carsote

, Mihai-Lucian Ciobica and

Claudiu Nistor

submission deadline 28 Feb 2026 | 4 articles | Viewed by 5445 | Submission Open

Keywords: thyroid neoplasia; thyroiditis; imaging; functional imaging; thyroidectomy; tumor markers; histological exam; molecular findings; pediatric population; pregnancy and thyroid conditions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Anesthesia and Pain Medicine

edited by Jamal Hasoon

submission deadline 28 Feb 2026 | 4 articles | Viewed by 5390 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Gynecological Oncology: Advanced Diagnosis and Management in 2025

edited by

Zoard T. Krasznai

and

Rudolf Lampé

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5314 | Submission Open

Keywords: gynecology; oncology; endometrial cancer; ovarian cancer; cervical cancer; diagnosis; staging; surgical methods; standardization of surgery; treatment; innovation; precision medicine; artificial intelligence; machine learning

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances and Approaches in Managing Neurological Disorders: Multi-Omics and P4 Medicine

edited by

Shashanka Ashili

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4787 | Submission Open

Keywords: multi-omics; neurological disorders; P4 medicine; Appomics; neurodegenerative disorders; neurodevelopmental disorders; personalized medicine; bioinformatics; aging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Alzheimer's Disease Diagnosis Based on Deep Learning

edited by Anees Abrol

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4616 | Submission Open

Keywords: Alzheimer's disease (AD); deep learning; MRI; demographic information; disease probability map; convolutional neural network (CNN)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Diagnosis and Management in Pediatric Surgery

edited by Ioannis A. Valioulis

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4611 | Submission Open

Keywords: pediatric surgery; neonatal surgery; pediatric urology; pediatric oncology; laparoscopy in children; robotic surgery for children; organ transplantation; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4355 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovative Diagnostic Approaches in Retinal Diseases

edited by

Benedetto Falsini

and Andrea Cusumano

submission deadline 28 Feb 2026 | 4 articles | Viewed by 4174 | Submission Open

Keywords: retinal diseases; electrophysiology; imaging; optical coherence tomography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Impacts and Value of Anatomy, 2nd Edition

edited by

Maria Piagkou

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3801 | Submission Open

Keywords: musculoskeletal anatomy; clinical anatomy; surgical anatomy; vascular; nervous system; anatomical variations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Insights for Skin Melanoma

edited by

Luca Roncati

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3436 | Submission Open

Keywords: skin melanoma; tissue biopsy; histopathological examination; immunohistochemistry; dermatoscopy; reflectance confocal microscopy; modern artificial intelligence; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis, Treatment, and Management of Hair Disorders

edited by Neil Jairath and

Vignesh Ramachandran

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3283 | Submission Open

Keywords: hair loss; alopecia; management; cicatricial; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management in Cardiac Intensive Care Medicine

edited by

Elad Asher

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3192 | Submission Open

Keywords: cardiac intensive care; cardiogenic shock; acute heart failure; hemodynamic monitoring; mechanical circulatory support; post-cardiac arrest care; critical care cardiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Application of Cone Beam Computed Tomography for Maxillofacial Diseases, Third Edition

edited by

Yiu Yan Leung

submission deadline 28 Feb 2026 | 4 articles | Viewed by 3166 | Submission Open

Keywords: cone-beam computed tomography; imaging; radiology; oral and maxillofacial surgery; dentistry; diagnosis; risk management; 3D printing; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Anatomy and Diagnosis of Peripheral Nervous System—2nd Edition

edited by

Alexandra Diana Vrapciu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2989 | Submission Open

Keywords: anatomy; peripheral nervous system; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Endocrinology Pathology

edited by

Mara Carsote

Ana Valea

and

Claudiu Nistor

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2989 | Submission Open

Keywords: histological classification and reporting; cytological analysis; fine-needle aspiration; molecular markers; immunohistochemistry; hormone; dynamic hormonal testing; endocrine tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Imaging in Bone and Soft-Tissue Sarcomas: Practice, Education, and Innovation—2nd Edition

edited by

Paolo Spinnato

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2974 | Submission Open

Keywords: soft-tissue sarcomas; bone sarcomas; imaging; MRI; CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Skin Diseases

edited by

Montserrat Fernández-Guarino

submission deadline 28 Feb 2026 | 4 articles | Viewed by 2888 | Submission Open

Keywords: dermatology; skin disease; molecular diagnostics; laboratory test; assessment of therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Trends in Cardiovascular Imaging: 2nd Edition

edited by

Hans-Christoph Becker

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2720 | Submission Open

Keywords: cardiac CT; cardiac MRI; hybrid and multimodality imaging; artificial intelligence and machine learning; coronary artery disease; myocardial tissue characterization; congenital heart disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Subjective Experiences of Decline and Dementia Risk: Cognitive, Functional, and Emotional Predictors of Cognitive Decline

edited by Katya Numbers

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2632 | Submission Open

Keywords: subjective cognitive decline (SCD); dementia risk; cognitive complaints; functional decline; emotional well-being; early diagnosis and intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Biomarkers for Cardiovascular Disease

edited by

Manuela Ciocoiu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2601 | Submission Open

Keywords: cardiovascular risk factors; hypertension; dyslipidemia; overweight; obesity; diabetes mellitus; metabolic syndrome; atherosclerosis; physical inactivity; biomarkers; cardiovascular disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Neural Networks in Medical Diagnosis

edited by

Hamid Reza Marateb

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2086 | Submission Open

Keywords: neural networks in diagnostics; medical imaging analysis; deep learning in healthcare; predictive modeling for disease detection; clinical decision support systems; interpretability and explainability in AI; biomedical data processing; personalized medicine applications

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Medical Microwave Radiometry for R&D and Practical Applications in 2025

edited by

Igor Goryanin

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2061 | Submission Open

Keywords: microwave radiometry; core body temperature; breast cancer detection; artificial intelligence; COVID-19 pneumonia; vulnerable plaque; carotid; hypothermia; hyperthermia; ischemic stroke; traumatic brain injury; rheumatoid arthritis; diabetic foot; brown adipose tissue activity; vesicoureteral reflux

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Ultrasound Elastography in Musculoskeletal Disorders: From Bench to Bedside

edited by Yoshiki Yamakoshi

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2013 | Submission Open

Keywords: ultrasound elastography; shear wave elastography; musculoskeletal ultrasound; tissue elasticity; tendon and ligament imaging; myofascial pain syndrome; sports medicine; rehabilitation; diagnostic imaging; muscle stiffness

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Radiomics in Clinical Diagnosis

edited by

Alfonso Reginelli

and

Vittorio Patanè

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1964 | Submission Open

Keywords: radiomics; clinical diagnosis; medical imaging; quantitative imaging biomarkers; artificial intelligence; machine learning; image analysis; precision medicine; computer-aided diagnosis; multimodal imaging; feature extraction; predictive modeling; diagnostic imaging; integrative diagnostics; imaging biomarkers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pathology for Forensic Diagnosis

edited by

Cristina Mondello

and Vincenzo Cianci

submission deadline 28 Feb 2026 | 3 articles | Viewed by 1816 | Submission Open

Keywords: forensic pathology; forensic medicine; forensic radiology; forensic genetics; forensic toxicology; postmortem interval; forensic odontology; forensic entomology; forensic anthropology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances and Challenges in the Diagnosis and Treatment of Rheumatic Diseases

edited by

Anastas Batalov

Mariela Geneva-Popova

and Zgurov Batalov

submission deadline 28 Feb 2026 | 3 articles | Viewed by 1678 | Submission Open

Keywords: rheumatology ; rheumatic diseases ; musculoskeletal ultrasound ; clinical diagnostics ; biomarkers ; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multidisciplinary Diagnostic Approaches to Infectious Pathologies in Surgical Specialties

edited by

Elena Adelina Toma

and

Octavian Enciu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1500 | Submission Open

Keywords: surgical infections; diagnostic advancements; antimicrobial resistance; molecular diagnostics; radiological imaging; microbiological assays; AI-driven diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Prenatal Diagnosis: From Morphological Evaluation to Genetic Testing

edited by

Antonio Pizzuti

and

Gioia Mastromoro

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1360 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound (US); fetal magnetic resonance imaging (MRI); chromosomal microarray analysis; next-generation sequencing; exome sequencing; genome sequencing; non-invasive prenatal screening; non-invasive prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostics in Maxillofacial Oncology and Trauma

edited by

Ioanna Kalaitsidou

and

Benoît Schaller

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1003 | Submission Open

Keywords: maxillofacial diagnostics; craniofacial trauma; oral and maxillofacial oncology; artificial intelligence in imaging; photon-counting CT (PCCT); molecular biomarkers; histopathology; radiomics; multimodal imaging; preoperative planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Trends and Future Directions in Radiotheragnostic Research: A Special Issue in Collaboration with ISRT 2025

edited by

Kalevi Kairemo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 940 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; targeted alpha therapy; PSMA; prostate cancer; neuroendocrine neoplasms; somatostatin analogs; daughter radionuclides; dosimetry; small-scale/micro-dosimetry; radiobiology; target chemistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

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