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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence in Cardiovascular and Stroke Imaging

edited by

Jasjit S. Suri

submission deadline 31 Mar 2026 | Viewed by 64 | Submission Open

Keywords: artificial intelligence; cardiovascular; stroke imaging; diagnosis; prognosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Eye Disease, 4th Edition

edited by

Jae-Ho Han

submission deadline 31 Mar 2026 | Viewed by 59 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; fundus image; optical coherence tomography; ophthalmology; retinal vessel; glaucoma; retinopathy; macular degeneration; image segmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Imaging in Multiple Sclerosis

edited by Emanuele Tinelli

submission deadline 31 Mar 2026 | Viewed by 57 | Submission Open

Keywords: multiple sclerosis; MRI; neuroimaging; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Musculoskeletal Tumors

edited by

Tomoki Nakamura

submission deadline 31 Mar 2026 | Viewed by 54 | Submission Open

Keywords: bone tumors; soft tissue tumors; metastatic bone tumors; diagnosis; chemotherapy; immunotherapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Radiology for Breast Cancer

edited by Romuald Ferré

submission deadline 31 Mar 2026 | Viewed by 52 | Submission Open

Keywords: breast cancer screening; digital breast tomosynthesis (DBT); contrast-enhanced mammography (CEM); abbreviated breast MRI; artificial intelligence and radiomics; ultrasound correlation; risk-stratified imaging pathways

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Diagnostic Approaches and Personalized Interventions for Sleep Disorders

edited by Dagmara Dimitriou, Zaid Awad and Mustafa Jaafar

submission deadline 31 Mar 2026 | Viewed by 44 | Submission Open

Keywords: sleep disorders; obstructive sleep apnoea; diagnosis; personalized treatment; neurodivergence; comorbidities; cross-cultural sleep; wearable technology; paediatric sleep; public health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Focus on Children's Oral Health: Advances in Pediatric Dentistry and Imaging Assessments

edited by Iole Vozza

submission deadline 31 Mar 2026 | Viewed by 36 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Diabetes Mellitus

edited by

Franklyn Iheagwam

and

Aw Tar-Choon

submission deadline 31 Mar 2026 | Viewed by 34 | Submission Open

Keywords: diabetes diagnosis; glycemic monitoring; personalized treatment; chronic complications; point-of-care testing; insulin resistance; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Diagnostics: From Algorithms to Clinical Impact

edited by

Ali Athar

, David Brown and

Hanem Ellethy

submission deadline 31 Mar 2026 | Viewed by 34 | Submission Open

Keywords: machine learning in healthcare; artificial intelligence in diagnostics; medical imaging and deep learning; generative AI in medicine; multimodal data integration; explainable and trustworthy AI; translational medical AI; clinical decision support systems; secure and privacy-compliant data utilization

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Cardiology

edited by Hélder Alexandre Correia Dores

submission deadline 31 Mar 2026 | Viewed by 33 | Submission Open

Keywords: cardiology; cardiac imaging; biomarkers; artificial intelligence (AI); wearable technology; precision diagnostics; point-of-care testing

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advances in Radiomics for Medical Imaging: Second Edition

edited by

Xiang Li

submission deadline 31 Mar 2026 | Viewed by 32 | Submission Open

Keywords: radiomics; PET/CT; SPECT/CT; medical imaging; cancers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancing Medical Imaging with AI: From Cutting-Edge Algorithms to Clinical Integration

edited by Kyong Joon Lee

submission deadline 31 Mar 2026 | Viewed by 31 | Submission Open

Keywords: artificial intelligence; medical imaging; deep learning; computer-aided diagnosis (CADx); diagnostic imaging; clinical validation; medical image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Biochemical Testing Applications in Clinical Diagnosis—2nd Edition

edited by

Donatella Coradduzza

submission deadline 31 Mar 2026 | Viewed by 27 | Submission Open

Keywords: biochemical testing; clinical diagnosis; biomarkers; point-of-care tests; innovative analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Application of PET/CT in Diagnosis and Treatment of Cancers—2nd Edition

edited by Alberto Miceli

submission deadline 31 Mar 2026 | Viewed by 24 | Submission Open

Keywords: PET/CT; 18F-FDG; cancers; diagnosis; cancer treatment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pediatric Ophthalmology Diagnostics and Management

edited by Mariola Dorecka and Bogumiła Wójcik-Niklewska

submission deadline 31 Mar 2026 | Viewed by 22 | Submission Open

Keywords: pediatric ophthalmology; children; congenital glaucoma; congenital cataract; cornea; strabismus; myopia; retinopathy of prematurity; amblyopia

(This special issue belongs to the Section Biomedical Optics)

Advances in Diagnosis, Treatment and Management of Gastrointestinal Diseases

edited by

Carmen Fierbinteanu-Braticevici

submission deadline 31 Mar 2026 | Viewed by 20 | Submission Open

Keywords: gastrointestinal diseases; liver diseases; biomarkers in GI disease; imaging in GI diagnosis (CT; MRI; ultrasound); non-invasive diagnostic tools; GI Endoscopic procedures; treatment approaches; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Oral Squamous Cell Carcinoma: Diagnostics and Management

edited by Konstantinos Paraskevopoulos and

Dimitris Tatsis

submission deadline 31 Mar 2026 | Viewed by 19 | Submission Open

Keywords: oral squamous cell carcinoma; molecular diagnostics; artificial intelligence in oncology; advanced imaging techniques; personalized medicine; immunotherapy for OSCC; targeted therapies; multidisciplinary care; genomic profiling; early detection strategies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging Research on Gastrointestinal Disorders: Second Edition

edited by

Takahiro Emoto

submission deadline 31 Mar 2026 | Viewed by 15 | Submission Open

Keywords: gastrointestinal diseases; inflammatory bowel disease; intestinal obstruction; irritable bowel syndrome; gastric cancer; signal and imaging processing; visualization techniques for the gastrointestinal tract

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Endometrial Diseases

edited by

Kotaro Kitaya

submission deadline 31 Mar 2026 | Viewed by 11 | Submission Open

Keywords: endometrial diseases; artificial intelligence; hysteroscopy; ultrasound; minimally invasive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Endoscopy—A New Era in Gastrointestinal Diagnostics

edited by

Anastasios Koulaouzidis

Ervin Toth

and

Mohammed Abdulrasak

submission deadline 31 Mar 2026 | Viewed by 10 | Submission Open

Keywords: AI-supported detection; classification; and workflow in endoscopy; innovations in capsule and device-assisted endoscopy; image enhancement technologies and real-time analytics; therapeutic endoscopic advances and new instrumentation; integration of digital tools and automation into clinical practice; perspectives on training; quality; and standardization; ethical and regulatory considerations in emerging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Hematologic Tumors of the Bone: From Diagnosis to Prognosis

edited by Fabio Stagno

submission deadline 31 Mar 2026 | Viewed by 6 | Submission Open

Keywords: bone marrow tumors; hematologic malignancies; diagnostic biomarkers; prognostic tools; targeted therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Wearable Sensors and Artificial Intelligence for Real-Time Disease Monitoring

edited by

Wei-Chih Lien

submission deadline 31 Mar 2026 | Viewed by 5 | Submission Open

Keywords: wearable sensors; artificial intelligence; real-time monitoring; digital health; biosensors; machine learning

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Breakthroughs in Advanced Medical X-Ray and CT Imaging: From Technology to Clinical Application

edited by Joyoni Dey

submission deadline 31 Mar 2026 | Viewed by 5 | Submission Open

Keywords: advanced X-ray CT imaging; X-ray CT interferometry; phase-contrast X-ray; photon-counting detectors

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosing, Treating, and Preventing Eye Diseases

edited by Ermete Giancipoli

submission deadline 16 Apr 2026 | 1 articles | Viewed by 1897 | Submission Open

Keywords: retinal disease; vitreoretinal surgery; cataract surgery; intraocular lens; cornea; glaucoma; neuro-ophthalmology; multimodal imaging; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Image Analysis and Machine Learning

edited by

Inzamam Nasir

and

Costin Teodor Streba

submission deadline 21 Apr 2026 | Viewed by 75 | Submission Open

Keywords: AI-enhanced clinical imaging workflows; deep learning for disease classification and segmentation; radiomics and multi-omics integration; federated learning and privacy-preserving analytics; next-generation medical image annotation techniques; explainable AI in diagnostic imaging; high-throughput screening in digital pathology; cross-domain adaptation and transfer learning in healthcare; prognostic and predictive imaging biomarkers; clinical decision support systems using machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Prognosis and Management of Breast Cancer

edited by

Marko Spasic

submission deadline 21 Apr 2026 | Viewed by 72 | Submission Open

Keywords: breast cancer; diagnostics; personalized medicine; breast surgery; individualized treatment; radiotherapy; immunotherapy; targeted therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Insights in Dental Diagnostics, Biomaterials and Digital Workflow

edited by

Marina Meleșcanu Imre

and

Ana Maria Cristina Țâncu

submission deadline 21 Apr 2026 | Viewed by 39 | Submission Open

Keywords: dental diagnostics; artificial intelligence (AI); digital dentistry; biomaterials; 3D printing; intraoral scanning; CAD/CAM; digital workflow; predictive analytics; clinical innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Progress in Gynecologic Oncology

edited by

Antoni Llueca

submission deadline 21 Apr 2026 | Viewed by 32 | Submission Open

Keywords: gynecologic oncology; early diagnosis; molecular diagnostics; imaging techniques; artificial intelligence; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics in the Emergency and Critical Care Medicine

edited by

Zhongheng Zhang

submission deadline 30 Apr 2026 | 11 articles | Viewed by 31499 | Submission Open

Keywords: diagnostics; emergency and critical care medicine; trauma; anesthesiology; respiratory failure; sepsis; cardiovascular disease; healthcare-associated infection prevention; end-of-life care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Prognosis of Sepsis

edited by

Zhongheng Zhang

submission deadline 30 Apr 2026 | 4 articles | Viewed by 15647 | Submission Open

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Latest News in Digital Pathology

edited by Tahir Mahmood

submission deadline 30 Apr 2026 | 4 articles | Viewed by 5290 | Submission Open

Keywords: digital pathology; generative AI; cancer diagnosis; cancer prognosis; imaging modalities; cancer grading; artificial intelligence in pathology; histopathology; image analysis; medical imaging; vision-language models in histopathology; large language models for pathology diagnostics; multimodal AI integration in digital pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Skin Disorders 2025

edited by Neil K. Jairath

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1295 | Submission Open

Keywords: artificial intelligence; dermatology; computer vision; machine learning; deep neural networks; large language models; personalized medicine; predictive analytics; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Interventional Pulmonology

edited by George A. Eapen

submission deadline 30 Apr 2026 | Viewed by 286 | Submission Open

Keywords: interventional pulmonology; minimally invasive procedures; pulmonary diagnostics; bronchoscopy; lung cancer; advanced imaging modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Approach and Innovations in the Different Dentistry Fields, 2nd Edition

edited by

Francesco Inchingolo

Giuseppina Malcangi

Gianna Dipalma

Angelo Michele Inchingolo

and

Ioana Roxana Bordea

submission deadline 30 Apr 2026 | Viewed by 88 | Submission Open

Keywords: diagnosis; oral surgery; implantology; orthodontic; endodontic; oral health; orthodontic diseases and innovation; tissue regeneration; reconstructive surgical procedures; tissue engineering; biomedical engineering; stem cells regeneration tissue; oral surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Epidemiological Diagnostics: Advances and Applications

edited by

Jinhui Tian

submission deadline 30 Apr 2026 | Viewed by 76 | Submission Open

Keywords: artificial intelligence in diagnostic epidemiology; machine learning for diagnostic screening; predictive diagnostic modeling; automated diagnostic evidence synthesis; AI-designed peptides for diagnostics; antimicrobial peptide diagnostics; AI peptide engineering for pathogen detection; AI-driven population health diagnostics; diagnostic health informatics; digital diagnostic epidemiology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Driven Precision Medicine: Innovations in Diagnosis, Prognosis, and Management Response

edited by

Feng Gao

submission deadline 30 Apr 2026 | Viewed by 70 | Submission Open

Keywords: precision medicine; artificial intelligence; clinical decision support; deep learning; large language models (LLMs); prognosis prediction; medical imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Biomedical Diagnostics and Analysis 2025

edited by

Prabal Datta Barua

Turker Tuncer

and

Sengul Dogan

submission deadline 30 Apr 2026 | Viewed by 69 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; medical signal and image processing; internet of medical things (IoMT); bioinformatics; explainable artificial intelligence; machine learning; uncertainty

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Pathogenesis, Diagnosis, and Management of Rheumatic Disease: Progress and Challenges

edited by Miguel Ángel González-Gay

submission deadline 30 Apr 2026 | Viewed by 55 | Submission Open

Keywords: rheumatic disease; systemic vasculitis; rheumatoid arthritis; metabolic syndrome; atherosclerosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 30 Apr 2026 | Viewed by 31 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Chronic Disease

edited by

Lin Zhang

submission deadline 30 Apr 2026 | Viewed by 24 | Submission Open

Keywords: biomarkers; digital health technologies; artificial intelligence in diagnostics; non-invasive imaging; genomic screening; point-of-care testing; risk stratification models; multi-omics integration

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Interventional Radiology in 2025–2026: From Technological Innovation to Clinical Optimization

edited by

Francesco Giurazza

submission deadline 30 Apr 2026 | Viewed by 20 | Submission Open

Keywords: emergency; oncology; arterial; vascular diseases; extravascular-bleedings; aneurysms; vascular malformations; neurointerventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Liver Tumors

edited by

Marija Radmilović-Radjenović

submission deadline 30 Apr 2026 | Viewed by 7 | Submission Open

Keywords: liver tumors; hepatocellular carcinoma; immunotherapy; imaging; oncology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnosis and Treatment of Chorioretinal Diseases: From Biomarkers to Imaging

edited by

Jay Kumar Chhablani

submission deadline 30 Apr 2026 | Viewed by 5 | Submission Open

Keywords: ocular imaging; biomarkers; retinal imaging; retinal diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Emerging Imaging Techniques in Reconstructive Microsurgery

edited by Marios N. Papadakis

submission deadline 30 Apr 2026 | Viewed by 2 | Submission Open

Keywords: reconstructive microsurgery; intraoperative imaging; indocyanine green angiography; high-resolution ultrasound; 3D imaging; magnetic resonance imaging (MRI); perfusion monitoring; imaging-guided surgery; dynamic thermography; surgical planning tools

(This special issue belongs to the Section Medical Imaging and Theranostics)

Point-of-Care Testing (POCT) for Infectious Diseases

edited by Rongzhang Hao

submission deadline 30 Apr 2026 | Submission Open

Keywords: point-of-care testing (POCT); microfluidic chip and biosensor; ultrafast detection techniques; AI-integrated testing systems; infectious disease; pathogen

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Artificial Intelligence in Magnetic Resonance Imaging

edited by

Aydin Eresen

submission deadline 30 Apr 2026 | Submission Open

Keywords: magnetic resonance imaging; artificial intelligence; diagnostic medicine; MRI data analysis; image processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Ovarian Cancer in 2025–2026: A Comprehensive Look at Characteristics, Screening, Diagnosis and Treatment

edited by

Edward J. Pavlik

submission deadline 1 May 2026 | 2 articles | Viewed by 3359 | Submission Open

Keywords: ovarian cancer; risk; treatment; detection; screening; trial design; treatment; collateral effects; endpoints; costs; efficacy; AI; sojourn time models; vaccines; PARP inhibitors; liquid biopsies; post treatment hematologic malignancies; HIPEC; STIC/STIL

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Nephrology

edited by

Marijn M. Speeckaert

submission deadline 30 May 2026 | 8 articles | Viewed by 24048 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endoscopic Diagnostics for Pancreatobiliary Disorders 2025

edited by

Masataka Kikuyama

submission deadline 31 May 2026 | 3 articles | Viewed by 2548 | Submission Open

Keywords: endoscopic ultrasonography; endoscopic retrograde cholangiopancreatography; EUS– FNA; SPACE; pancreatic cancer; bile duct caner; gallbladder cancer

(This special issue belongs to the Section Biomedical Optics)

Diagnostic Methods in Forensic Pathology, Third Edition

edited by

Gennaro Baldino

and

Elvira Ventura Spagnolo

submission deadline 31 May 2026 | 2 articles | Viewed by 1925 | Submission Open

Keywords: multidisciplinary approach; forensic pathology; sudden/unexpected death; sepsis and health infections; suicide; gender violence; post-mortem immunohistochemistry; post-mortem CT; virtopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

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