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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis and Management of Hematologic Malignancies

edited by

Ankur Varma

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2341 | Submission Open

Keywords: acute myeloid leukemia; chronic myeloid leukemia; myelodysplastic syndrome; myeloproliferative neoplasm; Hodgkin's lymphoma; non-Hodgkin's lymphoma; acute lymphocytic leukemia; chronic lymphocytic leukemia; bone marrow failure syndrome; juvenile myelomonocytic leukemia

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis, Prognosis and Management of Cardiovascular Disease in Patients with Rheumatic Conditions

edited by

Patrick H. M. C. Dessein

Miguel Angel Gonzalez-Gay

and

Iván Ferraz-Amaro

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1531 | Submission Open

Keywords: rheumatoid arthritis; rheumatic conditions; cardiovascular risk factors; atherosclerosis; left ventricular structure and function; arterial function; cardiovascular events; ischemic heart disease; ischemic stroke; heart failure; peripheral vascular disease; venous thrombotic disease; cardiovascular drugs; antirheumatic agents

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Laboratory Diagnosis in Microbial Diseases, 3rd Edition

edited by

Hsin-Yao Wang

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1445 | Submission Open

Keywords: genomics; proteomics; diagnostics; infections

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

OCT and OCTA Assessment of Retinal and Choroidal Diseases

edited by Andrei Theodor Bǎlǎşoiu and

Ovidiu Zlatian

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1443 | Submission Open

Keywords: optical coherence tomography; optical coherence tomography angiography; diabetic retinopathy; age related macular degeneration; retinal vascular diseases.

(This special issue belongs to the Section Biomedical Optics)

Advances in Dental Imaging, Oral Diagnosis, and Forensic Dentistry

edited by

Anastasia Mitsea

, Christos Angelopoulos and Aliki Rontogianni

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1052 | Submission Open

Keywords: automated segmentation; neural networks in dentistry; digital intraoral scanning; radiographic/surgical guides; virtual reality in dental imaging; 3D surgical stimulation; 3D facial reconstruction; forensic odontology; forensic dentistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Gastrointestinal Surgery: Diagnosis and Management in 2025

edited by

Federico Selvaggi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 772 | Submission Open

Keywords: gastrointestinal trauma; oligometastatic disease; mesorectal metastasis; lymphnode metastasis; minimally invasive surgical therapy; endoscopic diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Gynecological and Pediatric Imaging

edited by

Gabriele Masselli

submission deadline 31 Jan 2026 | 1 articles | Viewed by 598 | Submission Open

Keywords: gynecological imaging; pediatric imaging; obstetrics imaging; magnetic resonance imaging (MRI); computed tomography (CT); ultrasound; early detection; cancer; congenital anomalies; treatment response; outcome assessment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Hematological Disease

edited by Sapha Shibeeb

submission deadline 31 Jan 2026 | 1 articles | Viewed by 506 | Submission Open

Keywords: hematological diseases; leukaemia; molecular diagnostics; next-generation sequencing (NGS); precision medicine; predictive biomarkers; AI-assited diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound in the Diagnosis and Management of Skin Diseases—2nd Edition

edited by

Joanna Czajkowska

Norbert Kiss

and Miklós Gyöngy

submission deadline 31 Jan 2026 | 1 articles | Viewed by 329 | Submission Open

Keywords: skin diseases; ultrasound; skin cancer; machine learning; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Clinical and Interventional Gastroenterology

edited by

Antonio Facciorusso

and

Eyad Gadour

submission deadline 31 Jan 2026 | Viewed by 112 | Submission Open

Keywords: diagnostic endoscopy; AI in gastroenterology; biomarker discovery; capsule endoscopy; confocal laser endomicroscopy; early cancer detection; functional GI disorders; molecular diagnostics; non-invasive imaging; microbiome analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multidisciplinarity in Myeloid Neoplasms: Bridging Diagnostics and Clinical Insights

edited by Alexander Haushofer and Bernhard Strasser

submission deadline 31 Jan 2026 | Viewed by 111 | Submission Open

Keywords: acute myeloid leukemia (AML); myelodysplastic syndromes (MDS); myeloproliferative neoplasms (MPN); MDS/MPN genetic profiling; multidisciplinary collaboration; diagnostic innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Aspects of CTC Research for Basic Medicine and Clinical Application

edited by Hayao Nakanishi

submission deadline 31 Jan 2026 | Viewed by 68 | Submission Open

Keywords: CTC; metastasis; mobilization; cluster heterogeneity; routine blood test; genetic analysis; CTC organoid

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis, Treatment, and Prognosis of Breast Cancer

edited by

Marko Buta

submission deadline 31 Jan 2026 | Viewed by 68 | Submission Open

Keywords: breast cancer diagnosis; molecular profiling; artificial intelligence; targeted therapy; immunotherapy; treatment strategies; prognostic markers; triple-negative breast cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic, Predictive and Prognostic Biomarkers for Neurodegenerative Diseases

edited by Ionica Pirici

submission deadline 31 Jan 2026 | Viewed by 66 | Submission Open

Keywords: neurodegenerative diseases; biomarkers; medical imaging; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Opportunities in Laboratory Medicine in the Era of Genetic Testing

edited by

Fernanda De-Paris

submission deadline 31 Jan 2026 | Viewed by 60 | Submission Open

Keywords: laboratory medicine; genetic testing; molecular diagnostics; personalized medicine; clinical decision-making; infectious disease diagnosis; precision oncology

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Advances in Retinal Imaging

edited by

Rodolfo Mastropasqua

and

Maria Ludovica Ruggeri

submission deadline 31 Jan 2026 | Viewed by 51 | Submission Open

Keywords: retina; vitreoretinal diseases; inherited retinal dystrophies; diabetic retinopathy; age-related macular degeneration; retinal detachment; optical coherence tomography; imaging

(This special issue belongs to the Section Biomedical Optics)

Advances in Diagnostic and Interventional Nephrology

edited by Ammar Almehmi

submission deadline 31 Jan 2026 | Viewed by 46 | Submission Open

Keywords: dialysis access; fistula; graft; stent; peritoneal catheter; drug-coated balloon; EndoAVF; dialysis; vascular access dysfunction; interventional nephrology; diagnostic imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathogenesis and Early Diagnosis of HPV-Related Cancers and Pre-Cancers

edited by

Anna Daniela Iacobone

and

Marta Tagliabue

submission deadline 31 Jan 2026 | Viewed by 43 | Submission Open

Keywords: HPV-related cancer; molecular diagnostics; precancerous lesions; biomarkers; early detection; cervical cancer; anal cancer; oropharyngeal cancer; prognostic factors; HPV genotyping

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in the Diagnosis and Management of Respiratory Disease: From Biomarkers to Treatment Decisions

edited by

Konstantinos Kostikas

and

Athena Gogali

submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open

Keywords: respiratory biologics; bronchoscopy; airways disease; exhaled biomarkers; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Cardiac Magnetic Resonance Imaging: Current and Future Clinical Applications

edited by

Per Lav Madsen

submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open

Keywords: cardiomyopathy; cardiovascular physiology; ischemic heart disease; metabolic heart disease; stress MRI; heart failure with reduced ejection fraction; heart failure with preserved ejection fraction

Urinary Tract Infections: Advances in Diagnosis and Management

edited by

Paul Froom

submission deadline 31 Jan 2026 | Viewed by 33 | Submission Open

Keywords: urinary tract infections; diagnosis; management; antimicrobial therapy; urinalysis; urine culture; recurrent UTI; asymptomatic bacteriuria

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer

edited by

Qiang Lv

and Xiao Yang

submission deadline 31 Jan 2026 | Viewed by 33 | Submission Open

Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases, Second Edition

edited by

Stefano Francesco Crinò

submission deadline 31 Jan 2026 | Viewed by 32 | Submission Open

Keywords: endoscopic ultrasound; eRCP; radiomics; tissue acquisition; artificial intelligence; magnetic resonance imaging; cholangioscopy; pancreatic cancer; pancreatic cysts; hepatocellular carcinoma; cholangiocarcinoma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Beyond the Tipping Point: Advances in the Diagnosis and Management of Acute-on-Chronic Liver Failure and End-Stage Liver Disease

edited by Jonathan Soldera

submission deadline 31 Jan 2026 | Viewed by 30 | Submission Open

Keywords: liver cirrhosis; hepatorenal syndrome; acute-on-chronic liver failure; liver transplan-tation; biomarkers; diagnostic imaging; artificial intelligence; inflammation media-tors; prognosis; end-stage liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Lung Involvement in Connective Tissue Disease: Advances in Diagnosis and Management

edited by Laura Groșeanu

submission deadline 31 Jan 2026 | Viewed by 30 | Submission Open

Keywords: interstitial lung disease; connective tissue disease; complication; etiology; genetic risks; epigenetic changes; dysregulated immunity; CT patterns; mechanisms; screening; assessing; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Jan 2026 | Viewed by 28 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Biomarkers of Urological Diseases

edited by

Martin Pejchinovski

submission deadline 31 Jan 2026 | Viewed by 27 | Submission Open

Keywords: proteomics; biomarkers; diagnosis; prediction; treatment; clinical application; technical advances

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiovascular Diseases: Innovations in Diagnosis and Management

edited by Hisao Hara

submission deadline 31 Jan 2026 | Viewed by 26 | Submission Open

Keywords: myocardial infarction; biomarker; prognosis; coronary risk; residual risk; prognosis prediction

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multimodal Biomarkers, AI, and Quantum Biology for Brain Diagnostics

edited by

Igor Goryanin

submission deadline 31 Jan 2026 | Viewed by 22 | Submission Open

Keywords: artificial intelligence; quantum biology; neurodiagnostics; biomarkers; neuroimaging; electrophysiology; diagnostics; brain networks

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Role of Magnetic Resonance Imaging in Obesity and Diabetes: 2nd Edition

edited by

Per Lav Madsen

submission deadline 31 Jan 2026 | Viewed by 20 | Submission Open

Keywords: magnetic resonance imaging (MRI); obesity and diabetes; diabetic foot complications; brain atrophy; diabetic kidney disease (DKD); functional MRI; non-invasive imaging; early diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy

edited by Cristiano Spada and Daniele Salvi

submission deadline 31 Jan 2026 | Viewed by 17 | Submission Open

Keywords: gastrointestinal endoscopy; therapeutic endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); artificial intelligence; small bowel capsule endoscopy; bariatric endoscopy

(This special issue belongs to the Section Biomedical Optics)

Advances in the Diagnosis and Management of Morbid Obesity

edited by Justyna Domienik-Karłowicz

submission deadline 31 Jan 2026 | Viewed by 16 | Submission Open

Keywords: morbid obesity; obesity diagnosis; body composition analysis; visceral adiposity; metabolic syndrome; biomarkers in obesity; genetic predisposition; comorbidity assessment; imaging techniques; risk stratification

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Insights into the Diagnosis of Pediatric Cholestasis

edited by Paola Francalanci

submission deadline 31 Jan 2026 | Viewed by 13 | Submission Open

Keywords: extrahepatic cholestasis; intrahepatic cholestasis; biliary atresia; genetic liver disease; inborn errors of metabolism; jaundice; monogenic liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis, Management, and Prognosis of Liver Disease and Its Syndromes, Second Edition

edited by

Chien Hao Huang

submission deadline 31 Jan 2026 | Viewed by 12 | Submission Open

Keywords: acute liver disease; chronic liver disease; viral hepatitis; liver cirrhosis; non-alcoholic steatohepatitis (NASH); diagnosis; treatment; prognosis score

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Breast Diagnostics

edited by Takouhie Catherine Maldjian

submission deadline 31 Jan 2026 | Viewed by 11 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; breast imaging; breast cancer; breast cancer prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Sports Injuries

edited by

Ki-Mo Jang

submission deadline 31 Jan 2026 | Viewed by 9 | Submission Open

Keywords: sports injury; sports medicine; diagnosis; treatment; surgery; rehabilitation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Predictive Biomarkers in Oncology

edited by

Jun Zhang

submission deadline 31 Jan 2026 | Viewed by 6 | Submission Open

Keywords: predictive biomarkers; precision oncology; liquid biopsy; treatment response; biomarker validation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advanced Diagnosis and Treatment Plan for Orthodontic and Oro-Facial Rehabilitations—2nd Edition

edited by

Antonino Lo Giudice

submission deadline 31 Jan 2026 | Viewed by 4 | Submission Open

Keywords: CBCT; facial scan; oral imaging; orthodontics; digital dentistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Imaging in the Diagnosis and Management of Skin Diseases

edited by Lehang Guo

submission deadline 31 Jan 2026 | Viewed by 3 | Submission Open

Keywords: skin diseases; ultrasound imaging; optical coherence tomography (OCT) imaging; photoacoustic imaging; reflectance confocal microscopy (RCM) imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Genetic Diagnosis of Rare Neurological Disorders: Advances, Challenges, and Clinical Impact

edited by

Georgia Xiromerisiou

submission deadline 31 Jan 2026 | Viewed by 3 | Submission Open

Keywords: rare neurological disorders; genetic diagnosis; neurogenetics; next-generation sequencing; genotype– phenotype correlation; molecular diagnostics; clinical impact; personalized medicine; translational research; undiagnosed diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Trends in Ultrasound Imaging

edited by

Ştefan Cristian Vesa

and

Ingrid Andrada Vasilache

submission deadline 15 Feb 2026 | Viewed by 194 | Submission Open

Keywords: ultrasound; imaging; diagnostics; artificial intelligence; elastography; contrast-enhanced ultrasound; radiomics; 3D ultrasound; point-of-care ultrasound; interventional imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Maternal–Fetal and Neonatal Diagnostics

edited by Elisa Bevilacqua

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4469 | Submission Open

Keywords: high risk pregnancy; twin pregnancy; maternal– fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Current Perspectives and Gaps in the Diagnosis and Management of Rheumatic Diseases

edited by Vikas Majithia

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1532 | Submission Open

Keywords: rheumatology; rheumatic diseases; inflammatory connective tissue diseases; rheumatoid arthritis; systemic lupus erythematosus; vasculitis; spondyloarthritis; scleroderma; osteoarthritis; current perspective; diagnosis; treatment; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Imaging in Bone and Soft-Tissue Sarcomas: Practice, Education, and Innovation—2nd Edition

edited by

Paolo Spinnato

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1229 | Submission Open

Keywords: soft-tissue sarcomas; bone sarcomas; imaging; MRI; CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Neural Networks in Medical Diagnosis

edited by

Hamid Reza Marateb

submission deadline 28 Feb 2026 | 1 articles | Viewed by 816 | Submission Open

Keywords: neural networks in diagnostics; medical imaging analysis; deep learning in healthcare; predictive modeling for disease detection; clinical decision support systems; interpretability and explainability in AI; biomedical data processing; personalized medicine applications

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Musculoskeletal Radiology

edited by

Jernej Vidmar

submission deadline 28 Feb 2026 | Viewed by 92 | Submission Open

Keywords: musculoskeletal radiology; high-resolution MRI; ultrasound-guided interventions; artificial intelligence in imaging; CT imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Treatment, and Management of Hair Disorders

edited by Neil Jairath and

Vignesh Ramachandran

submission deadline 28 Feb 2026 | Viewed by 39 | Submission Open

Keywords: hair loss; alopecia; management; cicatricial; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Anatomy and Diagnosis of Peripheral Nervous System—2nd Edition

edited by

Alexandra Diana Vrapciu

submission deadline 28 Feb 2026 | Viewed by 38 | Submission Open

Keywords: anatomy; peripheral nervous system; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Management of Skin Diseases

edited by

Montserrat Fernández-Guarino

submission deadline 28 Feb 2026 | Viewed by 36 | Submission Open

Keywords: dermatology; skin disease; molecular diagnostics; laboratory test; assessment of therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management in Cardiac Intensive Care Medicine

edited by

Elad Asher

submission deadline 28 Feb 2026 | Viewed by 34 | Submission Open

Keywords: cardiac intensive care; cardiogenic shock; acute heart failure; hemodynamic monitoring; mechanical circulatory support; post-cardiac arrest care; critical care cardiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Displaying special issue 601-650 on page 13 of 14.

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