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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contemporary Achievements in Diagnosis and Treatment of Gynecological and Obstetric Conditions

edited by

Radmila Sparić

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2214 | Submission Open

Keywords: fibroid; endometriosis; pelvic pain; reproductive endocrinology; pregnancy complications; delivery; infertility; obstetrics; diagnosis; treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Laboratory Diagnosis of Infections

edited by Mònica Balaguer Gargallo

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2170 | Submission Open

Keywords: infections; laboratory diagnosis; biochemical markers; bacterial resistance

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence in Health Monitoring and Diagnosis: AI Meets Conventional Models—2nd Edition

edited by

Stanislav Makhanov

submission deadline 31 Aug 2026 | 4 articles | Viewed by 2012 | Submission Open

Keywords: artificial intelligence; medical image processing; deep learning; machine learning; diagnostics; health monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advanced Diagnostics in Head and Neck Oncology

edited by Xindong Fan, Siyi Li, Longwei Hu and

Yuchen Shen

submission deadline 31 Aug 2026 | 3 articles | Viewed by 2007 | Submission Open

Keywords: head and neck; tumor; surgical diagnosis; non-invasive diagnostic method; diagnostic biomarkers; intraoperative imaging; pathology; minimally invasive biopsy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Pediatric Diseases: 2nd Edition

edited by

Elena Tarca

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1903 | Submission Open

Keywords: pediatrics; neonatal medicine; congenital malformations; pediatric orthopedics and trauma; pediatric oncology; pediatric surgery; pediatric urology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Aspects of CTC Research for Basic Medicine and Clinical Application

edited by Hayao Nakanishi

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1507 | Submission Open

Keywords: CTC; metastasis; mobilization; cluster heterogeneity; routine blood test; genetic analysis; CTC organoid

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Challenges in Urology: From Diagnosis to Management—2nd Edition

edited by

and

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1492 | Submission Open

Keywords: complications; rare; urologic cancer; urinary tract infections; urology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnostic and Therapeutic Digestive Endoscopy

edited by Pier Alberto Testoni

submission deadline 31 Aug 2026 | Viewed by 1470 | Submission Open

Keywords: gastroenterology; digestive tract diseases; gastrointestinal endoscopy; early diagnosis; endocavitary therapy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Expanding Horizons: Optical Coherence Tomography in Cross-Specialty Diagnostic Practice

edited by

Nicusor Iftimia

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1439 | Submission Open

Keywords: optical coherence tomography; cross-specialty diagnosis; AI-assisted OCT; OCT angiography; multimodal imaging

(This special issue belongs to the Section Biomedical Optics)

New Advances in Chest Imaging

edited by

Davide Colombi

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1393 | Submission Open

Keywords: chest imaging; lung cancer; interstitial lung diseases; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Sports Injuries

edited by

Ki-Mo Jang

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1306 | Submission Open

Keywords: sports injury; sports medicine; diagnosis; treatment; surgery; rehabilitation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Cardiovascular and Vascular Imaging

edited by

Alfredo Mauriello

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1291 | Submission Open

Keywords: vascular disease; cardiovascular disease; POCUS; limb disease; vascular imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Electrocardiology: Diagnostic Innovations and Clinical Applications

edited by

Branislav Milovanovic

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1198 | Submission Open

Keywords: heart rate variability (HRV); deceleration capacity; acceleration capacity; late potentials; artificial intelligence; machine learning; autonomic nervous system; electrocardiographic biomarkers; risk stratification; predictive analytics; signal processing

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Diagnosis and Management of Oral Cancer: Challenges, Advances, and Multidisciplinary Integration

edited by Eleni A. Georgakopoulou

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1198 | Submission Open

Keywords: oral cancer; early diagnosis; oral squamous cell carcinoma; artificial intelligence; oral potentially malignant disorders; multidisciplinary management; tumor board; oral pathology; misinformation; dental screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Diagnostic Approaches in Cardiovascular and Metabolic Disorders: From Pathophysiology to Clinical Practice

edited by

Iris Bararu-Bojan

and

Manuela Ciocoiu

submission deadline 31 Aug 2026 | 3 articles | Viewed by 1143 | Submission Open

Keywords: biomarkers; cardiovascular diseases; metabolic disorders; diagnostic imaging; precision medicine; pathophysiology; early diagnosis; risk stratification; omics technologies; clinical application

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Eye Disease: Diagnosis, Management, and Prognosis—2nd Edition

edited by

Adam Wylęgała

submission deadline 31 Aug 2026 | 4 articles | Viewed by 1129 | Submission Open

Keywords: eye disease; diagnosis; prognosis; OCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Role of AI in Ultrasound, 2nd Edition

edited by

Hyuksool Kwon

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1117 | Submission Open

Keywords: artificial intelligence; medical ultrasound; diagnostic imaging; automated image interpretation; predictive modeling; personalized medicine; clinical workflow optimization; healthcare access; multidisciplinary innovation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Trends and Diagnosis of Autoimmune Diseases

edited by

Abdulla Watad

and

Yonatan Shneor Patt

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1101 | Submission Open

Keywords: autoimmunity; diagnosis; biomarkers; comorbidities; epidemiology; metabolic syndrome; autoinflammatory conditions; psoriasis; cardiovascular disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Breast Cancer: Second Edition

edited by

Fulvio Borella

and

Isabella Castellano

submission deadline 31 Aug 2026 | 1 articles | Viewed by 1100 | Submission Open

Keywords: prognostic and predictive factors; breast carcinoma; phylloid tumor; immunohistochemistry; diagnosis; breast cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Laboratory Diagnosis of Emerging and Recent Infectious Diseases

edited by

Chaeseung Lim

and

Woongsik Jang

submission deadline 31 Aug 2026 | Viewed by 1019 | Submission Open

Keywords: emerging infectious diseases; laboratory diagnostics; molecular testing; immunoassays; point-of-care testing; pathogen detection; public health surveillance

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnostic Approaches to Temporomandibular Disorders

edited by

Yiu Yan Leung

submission deadline 31 Aug 2026 | 1 articles | Viewed by 920 | Submission Open

Keywords: temporomandibular disorders; TMD; diagnostic approaches; imaging modalities; clinical assessment; TMJ; facial pain; MRI; CBCT; orofacial pain

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Diagnostic Radiology: AI, Advanced Imaging and Precision Medicine

edited by

Thomas Frauenfelder

submission deadline 31 Aug 2026 | 1 articles | Viewed by 901 | Submission Open

Keywords: medical imaging; worklfow optimization; vision-language models; clinical decision support; diagnostic radiology; AI agents in healthcare; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Diagnosis and Prognosis of Urologic Oncology

edited by

Juan Gómez Rivas

and Jesús Moreno Sierra

submission deadline 31 Aug 2026 | 1 articles | Viewed by 862 | Submission Open

Keywords: urologic cancers; prostate; bladder; kidney; testicular malignancies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Echocardiography Diagnostics

edited by Hatem Soliman Aboumarie

submission deadline 31 Aug 2026 | 1 articles | Viewed by 824 | Submission Open

Keywords: echocardiography innovations; cardiac imaging advancements; strain echocardiography; 3D/4D cardiac ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Musculoskeletal Imaging and Exercise Metabolism

edited by Jimin Ren

submission deadline 31 Aug 2026 | 1 articles | Viewed by 798 | Submission Open

Keywords: quantitative musculoskeletal MRI/MRS; exercise physiology; muscle bioenergetics; pH and metabolic flux; oxygenation and perfusion; rehabilitation and training; aging and sarcopenia; mineral metabolism and lipid infiltration

(This special issue belongs to the Section Medical Imaging and Theranostics)

Orthopedics and the Musculoskeletal System: Clinical Diagnosis and Management

edited by

Nahum Rosenberg

submission deadline 31 Aug 2026 | 1 articles | Viewed by 741 | Submission Open

Keywords: imaging diagnosis; AI-assisted diagnostic tools; biomarkers; shoulder pathology; bone healing; fracture management; spine disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Technologies in Advanced Cytopathological and Histopathological Diagnostics

edited by

Giuseppe Donato

and

Paolo Zaffino

submission deadline 31 Aug 2026 | Viewed by 733 | Submission Open

Keywords: digital pathology; molecular markers; cytopathology; histopathology; multimodal analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Precision Diagnosis and Management of Breast Cancer

edited by

Kefah Mokbel

and Jajini Varghese

submission deadline 31 Aug 2026 | 1 articles | Viewed by 620 | Submission Open

Keywords: breast cancer; precision diagnostics; risk-adapted treatment; treatment de-escalation; surgery; radiotherapy; systemic therapy; liquid biopsy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Hepatobiliary Diseases

edited by

Ivan Romic

submission deadline 31 Aug 2026 | 1 articles | Viewed by 402 | Submission Open

Keywords: hepatobiliary diseases; liver diagnostics; biliary diagnostics; cirrhosis; malignancies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Forensic Medicine and Postmortem Diagnosis

edited by

Hiroshi Ikegaya

submission deadline 31 Aug 2026 | Viewed by 354 | Submission Open

Keywords: forensic pathology; postmortem diagnosis; cause of death; postmortem imaging; forensic DNA analysis; forensic anthropology; toxicological analysis

Non-Ionizing Imaging in Oral and Maxillofacial Radiology: Advances in MRI and Ultrasound

edited by Gürkan Ünsal

submission deadline 31 Aug 2026 | Viewed by 339 | Submission Open

Keywords: dental MRI; high-field MRI; TMJ imaging; ultrasound; elastography; salivary gland imaging; point-of-care imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Approaches for Artificial Intelligence in Neuroimaging Applications, 2nd Edition

edited by

Kwang-Sig Lee

submission deadline 31 Aug 2026 | Viewed by 335 | Submission Open

Keywords: neuroimaging; machine learning; deep learning; explainable artificial intelligence; SHAP; GradCAM; generative artificial intelligence; BERT; GPT; multi-modal reinforcement learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning, Generative AI, and Explainable AI in Medical Diagnostics: From Data to Decisions

edited by

Steven L. Fernandes

submission deadline 31 Aug 2026 | Viewed by 328 | Submission Open

Keywords: deep learning; machine learning; generative AI; explainable AI; medical diagnostics; medical imaging processing and analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Advances in Neurodegenerative Diseases

edited by

Giulia Bivona

submission deadline 31 Aug 2026 | Viewed by 321 | Submission Open

Keywords: Alzheimer’ s disease (AD); Parkinson’ s disease (PD); amyotrophic lateral sclerosis (ALS); prognosis; diagnosis; biomarkers

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Prognosis of Gynecological Diseases: Advances and Challenges

edited by Stefano Bettocchi and Stefania Carlucci

submission deadline 31 Aug 2026 | Viewed by 314 | Submission Open

Keywords: gynecological diseases; hysteroscopy; diagnostic technologies; prognostic evaluation; biomarkers; imaging techniques; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Innovations in Endodontics and Regenerative Dental Medicine

edited by

Paulo J. Palma

submission deadline 31 Aug 2026 | Viewed by 303 | Submission Open

Keywords: endodontic diagnostics; regenerative endodontics; nanomaterials; magnetic resonance imaging; cone-beam computed tomography (CBCT); optical coherence tomography (OCT); dental imaging innovations; pulp vitality biomarkers; periapical disease profiling; artificial intelligence in dentistry; predictive diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multidisciplinary Approaches to Oral Cancer Diagnosis

edited by

Siu Wai Choi

submission deadline 31 Aug 2026 | Viewed by 301 | Submission Open

Keywords: oral cancer diagnosis; oral cancer progression; machine learning; prediction models; biomarkers; early prediction

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnostic Pathways for Pregnancy Complications and Gynecologic Disease

edited by Argyro Papadopoulou

submission deadline 31 Aug 2026 | Viewed by 292 | Submission Open

Keywords: pregnancy complications; prenatal diagnosis; placental disorders; preeclampsia prediction; infertility evaluation; endometriosis diagnosis; minimally invasive techniques; biomarkers; women’ s views; gynecologic oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Role of Magnetic Resonance Imaging in Obesity and Diabetes: 2nd Edition

edited by

Per Lav Madsen

submission deadline 31 Aug 2026 | Viewed by 286 | Submission Open

Keywords: magnetic resonance imaging (MRI); obesity and diabetes; diabetic foot complications; brain atrophy; diabetic kidney disease (DKD); functional MRI; non-invasive imaging; early diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI and Computational Tools in Gastrointestinal Diagnostics: Shaping the Future of Clinical Practice

edited by

Chang Bang

submission deadline 31 Aug 2026 | 1 articles | Viewed by 286 | Submission Open

Keywords: artificial intelligence; machine learning; gastrointestinal endoscopy; computer-aided diagnosis (CAD); human-ai interaction; automation bias & neglect; digestive diseases; precision medicine; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Rare Cancers: Improving Diagnosis and Prognosis Through Collaborative Research

edited by Chen-Wang Chang

submission deadline 31 Aug 2026 | Viewed by 280 | Submission Open

Keywords: rare cancer; diagnosis and prognosis; biomarker; early detection; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Computational and Functional Diagnostic Approaches in Behavioral and Clinical Neurosciences

edited by

Marco Esposito

Marcella Caputi

Roberta Fadda

and Antonio Cerasa

submission deadline 31 Aug 2026 | Viewed by 270 | Submission Open

Keywords: computational diagnostics; behavioral assessment; multimodal biomarkers; nutritional and metabolic indicators; physiological; neuroimaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advanced Radiomics in Precision Oncology

edited by

Shahin Zandieh

submission deadline 31 Aug 2026 | Viewed by 267 | Submission Open

Keywords: radiomics; deep radiomics; medical imaging; artificial intelligence (AI); precision medicine; quantitative imaging; deep learning; feature extraction; image analytics; big data

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Multimodality Cardiac Imaging: Enhancing Precision in Cardiology

edited by

Sanjeev Bhattacharyya

and Apostolos Vrettos

submission deadline 31 Aug 2026 | Viewed by 247 | Submission Open

Keywords: multimodality cardiac imaging; echocardiography; cardiac CT; cardiac MRI; transcatheter interventions; precision cardiology; imaging biomarkers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Lung Cancer—2nd Edition

edited by

Savvas Lampridis

and

Marco Scarci

submission deadline 31 Aug 2026 | Viewed by 245 | Submission Open

Keywords: lung cancer; diagnosis; screening; imaging; pathology; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Advances in the Diagnosis and Management of Skin Diseases and Skin Quality Enhancement

edited by

Peter Hsien Li Peng

and Leihong Flora Xiang

submission deadline 31 Aug 2026 | Viewed by 237 | Submission Open

Keywords: diagnostic focus: non-invasive diagnostics (dermoscopy; ultrasound(sonography); and OCT); dermatopathology; management focus: precision dermatology; lasers; energy based devices (EBDs); injectables; enhancement focus: skin quality; dermal remodeling

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Medicine in Cardiology: Applications in Risk Stratification, Diagnostics, Prognosis, and Management

edited by Aman Goyal and Zhuqing Shi

submission deadline 31 Aug 2026 | Viewed by 230 | Submission Open

Keywords: biomarkers; precision medicine; personalized medicine; diagnostics; risk; prognosis; cardiovascular medicine; heart failure; atrial fibrillation; coronary artery disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnosis of Acute Kidney Injury

edited by

Rolando Claure-Del Granado

and Nuttha Lumlertgul

submission deadline 31 Aug 2026 | Viewed by 204 | Submission Open

Keywords: AKI biomarkers; point-of-care testing; multi-omics integration; machine learning risk prediction; urinary proteomics; biomarker-guided decision support; functional renal imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Pain Medicine: Diagnostic and Management Innovations

edited by Yuchen Lee, Dongwoo Nam and Cheng-Hao Tu

submission deadline 31 Aug 2026 | Viewed by 185 | Submission Open

Keywords: pain medicine; chronic pain; neuropathic pain; nociplastic pain; biomarkers; imaging; quantitative sensory testing; artificial intelligence; digital health; multimodal analgesia; neuromodulation; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Point-of-Care Echocardiography in Emergency and Critical Care

edited by

Alfredo Mauriello

submission deadline 31 Aug 2026 | Viewed by 178 | Submission Open

Keywords: pocus; echocardiography; intensive cardiac care; shock; acute coronary syndrome

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

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