Functional Gastrointestinal Disorders (FGIDs): Diagnosis and Pathophysiology, Second Edition

Dear Colleagues,

FGIDs, such as functional dyspepsia and irritable bowel syndrome, are the most common disorders seen by gastroenterologists. FGIDs are often recognized by the coexistence of multiple morphologic and physiological abnormalities, including motility disturbance, visceral hypersensitivity, altered mucosal and immune function, altered gut microbiota, and altered central nervous system processing. FGIDs affect over 40% of people worldwide, decrease quality of life, and impose a significant burden on healthcare systems. An accurate diagnosis and better understanding of pathophysiology are critically important for FGIDs. Authors are invited to submit original research articles, mini-reviews, systematic reviews, meta-analyses, and case reports on the diagnosis and pathophysiology of FGIDs.

FGIDs: gastroesophageal reflux disease, non-cardiac chest pain, dysphagia, functional dyspepsia, gastroparesis, intestinal pseudo-obstruction, small intestinal bacterial overgrowth, intestinal gas, constipation, diarrhea, and fecal incontinence;

Diagnostic methods: esophageal manometric, electrogastrography, impedance, barostat, ultrasound, magnetic resonance imaging, anorectal manometry, and other novel methods;

Pathophysiology: gastrointestinal dysmotility, visceral hypersensitivity, disorders of the brain–gut interaction, autonomic dysfunction, impaired barrier function, dysbiosis, altered autoimmune mechanisms, inflammatory, altered brain functions, etc. 

Due to the nature of the journal, contributions solely on the management of FGIDs are not suitable for this Special Issue. If needed, potential contributors may send their abstracts to this Special Issue for clarification.

Dr. Gengqing Song
Guest Editor

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• functional gastrointestinal disorders
• diagnosis
• treatment approach
• ROME criteria