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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Diagnostics and Management of Stroke

edited by

Qiwen Deng

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3021 | Submission Open

Keywords: ischemic stroke; diagnostic; thrombolysis; endovascular thrombectomy; post-stroke cognitive impairment; secondary prevention; neuroinflammation; neuroprotection

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiovascular Diseases: Advances in Echocardiography and Cardiac Computed Tomography

edited by Vasileios Kamperidis

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2988 | Submission Open

Keywords: heart failure; echocardiography; valvular heart disease; strain imaging; cardiac computed tomography; atherosclerosis; cardiomyopathy; 3D imaging; coronary artery disease; CT FFR; perfusion imaging; stress echocardiography; TEE

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Developments in the Diagnosis of Skin Tumors: 2nd Edition

edited by

Sorina Danescu

submission deadline 31 Oct 2026 | Viewed by 2833 | Submission Open

Keywords: basal cell carcinoma; melanoma; benign tumors; cutaneous squamous cell carcinoma; Bowen’ s disease; actinic keratosis; diagnosis; biomarkers; imaging techniques; molecular diagnostics; histopathology; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Imaging for Maternal–Fetal Medicine

edited by

Alexandros Psarris

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2827 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound; fetal MRI; congenital anomalies; placental imaging; artificial intelligence in imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements and Innovations in the Diagnosis of Lung Cancer

edited by

Houssein A. Youness

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2810 | Submission Open

Keywords: lung cancer; diagnosis; biomarkers; artificial intelligence; robotic bronchoscopy; bronchoscopic imaging; endobronchial ultrasound; molecular profiling; genetic profiling; next-generation sequencing; tissue acquisition; low-dose CT screening; personalized medicine; medical imaging; lung nodules

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management in Emergency and Hospital Medicine–2nd Edition

edited by

Nin-Chieh Hsu

submission deadline 31 Oct 2026 | Viewed by 2584 | Submission Open

Keywords: diagnosis; treatment; management; hospital medicine; emergency medicine; point-of-care ultrasound; decision making; transitional care; palliative care; quality improvement

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Biomarkers of Urological Diseases

edited by

Martin Pejchinovski

and

Jochen Metzger

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2560 | Submission Open

Keywords: proteomics; biomarkers; diagnosis; prediction; treatment; clinical application; technical advances

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Maternal–Fetal Medicine

edited by Roxana Elena Bohiltea

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2521 | Submission Open

Keywords: maternal– fetal medicine; pregnancy; prenatal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Progress in Gynecologic Oncology

edited by

Antoni Llueca

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2436 | Submission Open

Keywords: gynecologic oncology; early diagnosis; molecular diagnostics; imaging techniques; artificial intelligence; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Laboratory Medicine—from Research to Clinical Implementation

edited by Kelvin Y. K. Chan and Sergio Bernardini

submission deadline 31 Oct 2026 | Viewed by 2250 | Submission Open

Keywords: laboratory medicine; clinical practice; laboratory diagnosis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Clinical Diagnosis and Management of Metabolic Bone Diseases

edited by

Maria Lucia Fleiuss Farias

submission deadline 31 Oct 2026 | Viewed by 2174 | Submission Open

Keywords: bone; PTH; hyperparathyroidism; chronic kidney disease-metabolic bone disorder; osteoporosis; DXA; HR-pQCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Machine Learning for Medical Image Processing and Analysis in 2026

edited by Wei Shao

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2013 | Submission Open

Keywords: machine learning; medical image processing; diagnostic accuracy; healthcare; algorithms

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Cardiovascular Imaging, 2nd Edition

edited by

Riemer H.J.A. Slart

submission deadline 31 Oct 2026 | 4 articles | Viewed by 1962 | Submission Open

Keywords: cardiovascular imaging; noninvasive imaging; diagnosis; prognosis; marker

(This special issue belongs to the Section Medical Imaging and Theranostics)

Neurological Diseases: Novel Biomarkers for Diagnosis and Management

edited by

Costanza Maria Cristiani

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1895 | Submission Open

Keywords: biomarkers; laboratory medicine; neuroimaging; neurological diseases; treatment; management; clinical diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Meningitis—2nd Edition

edited by

Georgina Tzanakaki

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1788 | Submission Open

Keywords: bacterial meningitis; invasive meningococcal disease; molecular diagnostics; molecular typing; laboratory surveillance; molecular epidemiology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Pediatric Ophthalmology Diagnostics and Management

edited by Mariola Dorecka and Bogumiła Wójcik-Niklewska

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1773 | Submission Open

Keywords: pediatric ophthalmology; children; congenital glaucoma; congenital cataract; cornea; strabismus; myopia; retinopathy of prematurity; amblyopia

(This special issue belongs to the Section Biomedical Optics)

Diagnosis and Management of Diabetes Mellitus

edited by

Franklyn Iheagwam

and

Tar-Choon Aw

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1764 | Submission Open

Keywords: diabetes diagnosis; glycemic monitoring; personalized treatment; chronic complications; point-of-care testing; insulin resistance; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Future of Diagnostics: Exploring the Role of Artificial Intelligence in Medicine 2026

edited by

Shang-Ming Zhou

, Neil Vaughan and Jiaxiang Zhang

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1585 | Submission Open

Keywords: diagnostics; artificial intelligence; medicine; healthcare; future

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic, Predictive and Prognostic Biomarkers for Neurodegenerative Diseases

edited by

Ionica Pirici

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1558 | Submission Open

Keywords: neurodegenerative diseases; biomarkers; medical imaging; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

From Mystery to Diagnosis: Redefining Medical Practice Through Rare Disease Diagnostics

edited by

Emilia Severin

submission deadline 31 Oct 2026 | Viewed by 1509 | Submission Open

Keywords: rare disease; diagnostics; molecular testing; advanced imaging; artificial intelligence

Emerging Insights in Dental Diagnostics, Biomaterials and Digital Workflow

edited by

Marina Meleșcanu Imre

and

Ana Maria Cristina Țâncu

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1427 | Submission Open

Keywords: dental diagnostics; artificial intelligence (AI); digital dentistry; biomaterials; 3D printing; intraoral scanning; CAD/CAM; digital workflow; predictive analytics; clinical innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Management of Multisystem Wilson’s Disease

edited by

Tomasz Litwin

and

Agnieszka Antos

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1349 | Submission Open

Keywords: Wilson’ s disease; brain magnetic resonance imaging; biomarkers; copper metabolism; Wilson’ s disease mimicking disorders; zinc; chelators; liver transplantation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Advances in Fetal Medicine: Diagnosis and Management

edited by

Felix Rafael De Bie

submission deadline 31 Oct 2026 | Viewed by 1226 | Submission Open

Keywords: prenatal diagnosis; fetal therapy; congenital anomalies; imaging; molecular diagnostics; fetal intervention; ethics; precision fetal medicine; congenital diaphragmatic hernia; spina bifida; gastroschisis; sacro-coccygeal teratoma; vein of galen; twin– twin transfusion syndrome; congenital cardiac malformation; congenital pulmonary airway malformation; lower urinary tract obstruction

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hematology: Diagnostic Techniques and Assays, 2nd Edition

edited by Chihyun Cho

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1104 | Submission Open

Keywords: diagnostic; hematology; technique; assay; biomarkers

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Prognosis in Otorhinolaryngology and Head and Neck Surgery

edited by

Leandro Luongo Matos

submission deadline 31 Oct 2026 | Viewed by 1019 | Submission Open

Keywords: otorhinolaryngologic neoplasms; head and neck neoplasms; diagnostic techniques and procedures; prognosis; biomarkers; tumor; precision medicine; artificial intelligence; radiomics; molecular diagnostic techniques; disease progression

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Musculoskeletal Radiology

edited by

Jernej Vidmar

submission deadline 31 Oct 2026 | 1 articles | Viewed by 946 | Submission Open

Keywords: musculoskeletal radiology; high-resolution MRI; ultrasound-guided interventions; artificial intelligence in imaging; CT imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Endocrine Disorders

edited by

Hugo Mendieta Zerón

submission deadline 31 Oct 2026 | 1 articles | Viewed by 879 | Submission Open

Keywords: type 2 diabetes; growth hormone deficiency; dyslipidemia; osteoporosis; hyperprolactinemia; hyperthyroidism

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Focus on Children's Oral Health: Advances in Pediatric Dentistry and Imaging Assessments

edited by

Iole Vozza

submission deadline 31 Oct 2026 | 2 articles | Viewed by 874 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence and Pattern Recognition Methods for the Automatic Detection and Evaluation of Neurological Disorders, 3rd Edition

edited by

Juan Rafael Orozco-Arroyave

submission deadline 31 Oct 2026 | 1 articles | Viewed by 843 | Submission Open

Keywords: machine learning; neurodegenerative diseases; diagnosis; detection and evaluation; monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Perspectives in Forensic Diagnosis, 2nd Edition

edited by

Stavroula A. Papadodima

and

Laurent Martrille

submission deadline 31 Oct 2026 | 2 articles | Viewed by 838 | Submission Open

Keywords: autopsy; forensic clinical examination; forensic pathology; postmortem CT/MRI; multidisciplinary approach; post‑mortem biochemical analysis; forensic anthropology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Neurosurgical Diagnostics: Imaging, Intraoperative Monitoring, and Prognostic Assessment

edited by Janez Ravnik

submission deadline 31 Oct 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: diagnostics; MR imaging; function imaging; neurosurgery; brain; spine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Imaging for Diagnosis and Management of Musculoskeletal Disorders

edited by

Takeshi Fukuda

submission deadline 31 Oct 2026 | 1 articles | Viewed by 448 | Submission Open

Keywords: musculoskeletal imaging; magnetic resonance imaging (MRI); computed tomography (CT); photon-counting CT; advanced imaging techniques; quantitative imaging; inflammatory arthritis; trauma; sports-related disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical and Biochemical Diagnosis and Management of Obesity

edited by

Iwona Beń-Skowronek

submission deadline 31 Oct 2026 | 1 articles | Viewed by 441 | Submission Open

Keywords: obesity; biomarker; body composition; metabolic assessment; multidisciplinary management; bariatric surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Wearable Devices for Health Monitoring and Disease Diagnosis

edited by Robert LeMoyne

submission deadline 31 Oct 2026 | Viewed by 425 | Submission Open

Keywords: wearable devices; health monitoring; diagnosis; sensors; artificial intelligence

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnostic Imaging in Acute Respiratory Distress Syndrome

edited by

Denise Battaglini

submission deadline 31 Oct 2026 | Viewed by 401 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); computed tomography (CT); lung ultrasound (LUS); electrical impedance tomography (EIT); positron emission tomography (PET); imaging biomarkers; quantitative imaging analysis; multimodal imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Liquid Biopsy for Early Detection and Monitoring of Cancer

edited by Nicola Normanno,

Paola Ulivi

and

Tania Rossi

submission deadline 31 Oct 2026 | Viewed by 359 | Submission Open

Keywords: ctDNA; circulating tumor cells; microRNAs; exosomes; methylation; fragmentomics; early detection; minimal residual disease; artificial intelligence

Laboratory Testing in Endocrine Diseases

edited by

Tar-Choon Aw

and Chin Shern Lau

submission deadline 31 Oct 2026 | Viewed by 300 | Submission Open

Keywords: endocrine diseases; laboratory testing; clinical correlation; hormone testing; diagnosis and management

(This special issue belongs to the Section Clinical Laboratory Medicine)

Clinical Predictors of Endodontic Treatment Outcomes

edited by

Paulo J. Palma

and

João F. Brochado Martins

submission deadline 31 Oct 2026 | Viewed by 297 | Submission Open

Keywords: diagnosis; endodontics; radiographic imaging; CBCT; outcomes; histology; preoperative diagnosis; apical periodontitis status; clinical predictors treatment planning; improve patient communication; and guide evidence-based decision-making

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Use of Portable Devices in Emergency Medicine, Second Edition

edited by

Junko Yamaguchi

submission deadline 31 Oct 2026 | Viewed by 233 | Submission Open

Keywords: portable devices; emergency medicine; smartphone applications; wearable technology; diagnostic accuracy; remote triage; real-time monitoring; emergency medicine education; point-of-care testing; telemedicine

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Functional Parameters in Quantitative CT: Clinical Significance and Diagnostic Applications

edited by Massimo Cressoni and Fatemeh Darvizeh

submission deadline 31 Oct 2026 | Viewed by 227 | Submission Open

Keywords: computed tomography; dual energy; adrenal adenoma; cardiac function; kidney function; perfusion; contrast media; flow velocity; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Heart Disease, 3rd Edition

edited by

Yuli Huang

submission deadline 31 Oct 2026 | Viewed by 223 | Submission Open

Keywords: heart disease; coronary artery disease; arrhythmia; heart failure; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Biological Rhythms in Laboratory Medicine

edited by

Fernando Marques-Garcia

and

Rubén Fossión

submission deadline 31 Oct 2026 | Viewed by 221 | Submission Open

Keywords: biological rhythms; laboratory medicine; biomarkers; physiology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Innovations and Challenges in Breast Imaging

edited by

Gary J. Whitman

submission deadline 31 Oct 2026 | Viewed by 220 | Submission Open

Keywords: breast imaging; breast ultrasound; mammography; digital breast tomosynthesis; digital mammography; contrast-enhanced mammography; breast MRI; molecular breast imaging; imaging-guided interventional breast procedures; artificial intelligence in imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Molecular Pathology in Maternal–Fetal Medicine: Enabling Precision Diagnosis and Prenatal Management

edited by

Chenming Xu

, Songchang Chen and Yousheng Yan

submission deadline 31 Oct 2026 | Viewed by 204 | Submission Open

Keywords: molecular pathology; prenatal screening; prenatal diagnosis; pregnancy complications; bioinformatics; clinical artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Laboratory Hematology and Flow Cytometry

edited by

John L. Frater

and Cara Lunn Shirai

submission deadline 31 Oct 2026 | Viewed by 194 | Submission Open

Keywords: flow cytometry; spectral flow cytometry; imaging flow cytometry; machine learning in flow cytometry; artificial intelligence in flow cytometry; machine learning in laboratory hematology; artificial intelligence in laboratory hematology; hematology laboratory information systems; automated hematology; complete blood count; hemoglobin analysis

(This special issue belongs to the Section Clinical Laboratory Medicine)

Novel Technologies in Orthopedic Surgery: Diagnosis and Management, 2nd Edition

edited by Giuseppe Salvatore and Alessandro Mazzola

submission deadline 31 Oct 2026 | Viewed by 185 | Submission Open

Keywords: orthopedic surgery; orthopedic diagnosis; orthopedics; computer navigation and augmented reality; robotics; digital templating; 3D printing; artificial intelligence; machine learning; deep learning

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Vasculitis—2nd Edition

edited by

Alicia Rodríguez-Pla

submission deadline 31 Oct 2026 | Viewed by 183 | Submission Open

Keywords: vasculitis; advances; updates; management; treatment; therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Esophageal Disorders: Modern Approaches

edited by

Wojciech Blonski

and John Jacobs

submission deadline 31 Oct 2026 | Viewed by 176 | Submission Open

Keywords: eosinophilic esophagitis; GERD; achalasia; esophagogastric junction outflow obstruction; lichen planus

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning-Based Medical Diagnostics

edited by

Hamid Reza Marateb

submission deadline 31 Oct 2026 | Viewed by 172 | Submission Open

Keywords: deep learning in medical diagnostics; multimodal diagnostic data fusion; AI-assisted medical imaging; biomedical signal analysis; computer-assisted diagnosis; explainable artificial intelligence in healthcare; wearable and point-of-care diagnostics; clinical validation of AI models; intelligent medical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Inflammatory and Infectious Skin Diseases: From Diagnostics to Management

edited by