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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Diagnosis and Management in Emergency and Hospital Medicine

edited by

Nin-Chieh Hsu

submission deadline 31 Dec 2025 | 4 articles | Viewed by 3644 | Submission Open

Keywords: diagnosis; treatment; management; hospital medicine; emergency medicine; point-of-care ultrasound; decision making; transitional care; palliative care; quality improvement

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathology and Diagnosis of Head and Neck Diseases

edited by

Eliano Cascardi

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3602 | Submission Open

Keywords: head and neck disease; histopathology; oral tumors; cancer; biomarkers; digital pathology; AI applications; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Sepsis

edited by

Zoran Todorovic

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3505 | Submission Open

Keywords: sepsis; biomarkers; diagnosis; personalized medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Dental Diagnostics

edited by

Dirk Ziebolz

and Margherita Fontana

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3384 | Submission Open

Keywords: diagnosis; diagnostic imaging; artificial intelligence; caries; periodontitis; stomatognathic diseases

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Lung Cancer: Screening, Diagnosis and Management: 2nd Edition

edited by

Fu-Zong Wu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3383 | Submission Open

Keywords: lung cancer; LDCT; overdiagnosis; artificial intelligence; deep learning; prognosis; radiomics; texture analysis; thoracic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Metabolic Diseases: Diagnosis, Management, and Pathogenesis

edited by Dee Pei

submission deadline 31 Dec 2025 | 4 articles | Viewed by 3101 | Submission Open

Keywords: metabolic disease; obesity; aging; machine learning; pathophysiology; prevalence; ethnic differences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Impacts and Challenges in Capsule Endoscopy

edited by

Anastasios Koulaouzidis

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3070 | Submission Open

Keywords: capsule endoscopy; diagnostic endoscopy; small bowel evaluation; non-invasive exploration

(This special issue belongs to the Section Biomedical Optics)

Images in the Diagnosis and Treatment of Macular Edema

edited by

Gawęcki Maciej

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3015 | Submission Open

Keywords: macular edema; diagnostic imaging; optical coherence tomography (OCT); fluorescein angiography; retinal imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Alzheimer's Disease: Diagnosis, Pathology and Management

edited by

Liam L. Chen

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2992 | Submission Open

Keywords: Alzheimer's disease; neuropathology; PET; MRI; CT; dementia; neurodegeneration; immunotherapy; treatment strategy; disease management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Epidemiological Diagnostics: Detecting and Controlling Infectious Diseases

edited by

Sri Banerjee

and W. Sumner Davis

submission deadline 31 Dec 2025 | 4 articles | Viewed by 2983 | Submission Open

Keywords: epidemiological diagnostics; disease control; clinical practice and patient care; public health; infectious diseases

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Pathology and Diagnosis of Neurological Disorders, 2nd Edition

edited by James Yip

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2783 | Submission Open

Keywords: stroke; CNS tumors; neurodegenerative diseases; traumatic brain injury

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostics and Therapeutic Explorations in Aging

edited by

Alvita Vilkevičiūtė

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2722 | Submission Open

Keywords: molecular markers; genetics; epigenetics; biochemistry; biomarkers; telomeres; age-related disease; senescence; mitochondrial dysfunction; immunogenetics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Technologies and Tools Used for Risk Assessment of Diseases

edited by

Chih-Wei Huang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2611 | Submission Open

Keywords: digital health; AI in healthcare; machine learning; disease risk prediction; medical imaging; wearable technology; big data analytics; telemedicine; personalized medicine; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Ultrasound Diagnosis in Maternal Fetal Medicine Practice

edited by

Kwok-yin Leung

Ka-Wang Cheung

and Lau Wai-Lam

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2571 | Submission Open

Keywords: obstetric ultrasound; placenta; fetal abnormalities; color doppler

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances of Endoscopic Ultrasound in Diagnostics and Therapeutics

edited by

Antonio Facciorusso

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2467 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic advances; image resolution; tissue sampling; echoendoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

The Applications of Radiomics in Precision Diagnosis

edited by

Sai Kit Lam

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2465 | Submission Open

Keywords: artificial intelligence in precision diagnosis; disease classification; early diagnosis; imaging biomarkers; radiomics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI in Radiology and Nuclear Medicine: Challenges and Opportunities

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2418 | Submission Open

Keywords: diagnosis; prognosis; radiology; nuclear medicine; artificial intelligence (AI)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Vascular Diseases

edited by Tiffany R. Bellomo and Abhisekh A. Mohapatra

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2391 | Submission Open

Keywords: diagnosis; management; vascular diseases; marker; non-invasive imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Clinical Diagnosis, Prognosis, and Management of Gastrointestinal Disease

edited by

Adrian Saftoiu

Bogdan Silviu Ungureanu

and

Irina M. Cazacu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2324 | Submission Open

Keywords: gastrointestinal diseases; colon cancer; appendicitis; clinical outcomes; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Immunological, Allergic and Inflammatory Disorders

edited by

Zenon Brzoza

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2100 | Submission Open

Keywords: diagnostics; treatment; allergic diseases; autoimmune; immunodeficiency and autoinflammatory syndromes; inflammatory disorders

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Emergency and Critical Care Medicine: Diagnosis and Management

edited by

Ivan Gornik

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2020 | Submission Open

Keywords: ICU; emergency medicine; trauma and injury; acute illness; accurate diagnosis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Trends in Musculoskeletal Imaging

edited by

Ugo Carraro

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2002 | Submission Open

Keywords: genetic and acquired skeletal muscle disorders; mobility functional tests; skeletal muscle imaging; light and electron microscopy; quantitative tissue densitometry by 3D and 2D color CT and MRI; blood and mouth fluid biomarkers; targeted management and follow-up in mobility medicine; functional electrical stimulation of denervated and reinnervating muscles; home full-body in-bed gym exercise; hemi-fasting and other nutritional supplements of mobility medicine in aging; spa; thermal; and balneotherapy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Cardiovascular Diseases: Advances in Diagnosis and Management

edited by

Thien Tan Tri Tai Truyen

submission deadline 31 Dec 2025 | Viewed by 1937 | Submission Open

Keywords: cardiovascular diseases; predictive risk score; mortality; prognosis; artificial intelligence; machine learning; large language models

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Bone and Joint Imaging—3rd Edition

edited by

Yuichi Yoshii

submission deadline 31 Dec 2025 | 3 articles | Viewed by 1898 | Submission Open

Keywords: musculoskeletal imaging; machine learning; bone imaging; computed tomography; ultrasound imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging in Oral Surgery: Advancing the Frontiers of Precision Diagnosis and Treatment Planning

edited by Anusha Vaddi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1848 | Submission Open

Keywords: oral surgery; digital radiography; treatment planning; diagnosis; augmented reality; 3D printing

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Maternal and Fetal Medicine Research: from Diagnostics to Prognosis

edited by

Edward Araujo Júnior

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1801 | Submission Open

Keywords: maternal; fetal; perinatal period; prenatal diagnosis; pregnancy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management in Urology

edited by

Roberto Falabella

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1728 | Submission Open

Keywords: minimally invasive surgery; early diagnosis; cancer biomarkers; diagnostic technology; surgical challenges; early diagnosis in urological cancers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Personalized Medicine

edited by Otilia Țica

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1714 | Submission Open

Keywords: cardiovascular disease; biomarkers; precision medicine; diagnostics; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Prognostic Factors for Pediatric Tumors, 2nd Edition

edited by

Maria Kourti

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1692 | Submission Open

Keywords: childhood cancer; prognostic factors; acute leukemia; solid tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pathological Speech Classification and Processing for Advanced Medical Diagnosis

edited by

Juan Rafael Orozco-Arroyave

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1618 | Submission Open

Keywords: pathological speech; medical diagnosis; classification and processing; Parkinson's disease; hypokinetic dysarthria; dysarthria; aphasia; voice disorders; dysphonia; AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Hearing and Audiology Science: Diagnosis and Management

edited by

Yu Sun

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1591 | Submission Open

Keywords: hearing loss; genetic deafness; cochlear implants; hair cell regeneration; central auditory processing; vestibular disorders; tinnitus intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging of Brain Disease, Second Edition

edited by

Rosalinda Calandrelli

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1473 | Submission Open

Keywords: adenomas; craniopharyngiomas; skull base lesions; infections; cystic lesions; vascular lesions; MRI; CT; radiomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Heart Failure: Clinical Diagnosis, Treatment, and Prognosis

edited by

Massimo Mapelli

and Irene Mattavelli

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1299 | Submission Open

Keywords: heart failure; clinical diagnosis; treatment advances; precision medicine; exercise evaluation; CPET

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multimodal Imaging: Enhancing Precision Medicine Across Diverse Clinical Pathways

edited by

Mariano Scaglione

and Salvatore Masala

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1191 | Submission Open

Keywords: CT; XR; CT US; MRI; functional MRI; PET; SPECT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Sleep and Respiratory Medicine

edited by Cheng-Yu Tsai

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1186 | Submission Open

Keywords: sleep and respiratory disorders; chest medicine; AI in healthcare; digital technology; precision diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis of Nervous System Diseases—3rd Edition

edited by

Vasileios T. Papaliagkas

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1114 | Submission Open

Keywords: neuroimaging; neurodegenerative diseases; Alzheimer's disease; cognitive impairment; brain tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Gastrointestinal Disease: Diagnosis and Management in 2025

edited by

Eun-Sun Kim

and

Kwang-Sig Lee

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1103 | Submission Open

Keywords: gastrointestinal disease; artificial intelligence; gastrointestinal cancer; inflammatory bowel disease; endoscopic AI; large language models

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Future Trends in Diagnostic and Interventional Radiology

edited by

Francesco Giurazza

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1080 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; artificial intelligence; minimally invasive therapy; radiomics; precision medicine; multidisciplinary research

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Hematology and Oncology, 2nd Edition

edited by Chohao Lee

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1066 | Submission Open

Keywords: hematological malignancies; lymphoma; leukemia; multiple myeloma; precision medicine; immunotherapy; genomics; targeted therapies

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Advances in Digestive Endoscopy

edited by Dominique Béchade

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1040 | Submission Open

Keywords: digestive endoscopy; colonoscopy; endoscopic ultrasound; interventional endoscopy; EUS-Guided Fine-Needle Aspiration (EUS-FNA); EUS-Fine Needle Biopsy (EUS-FNB); Endoscopic Retrograde Cholangiopancreatography (ENCR)

(This special issue belongs to the Section Biomedical Optics)

Advances in Oral Pathology of Basic and Clinical Cancer Research

edited by

Jun-Ichi Tanuma

submission deadline 31 Dec 2025 | 2 articles | Viewed by 951 | Submission Open

Keywords: oral cancer; molecular pathology; tumor microenvironment (TME); immunotherapy; epigenetics; diagnosis; targeted therapy; personalized medicine; AI and image analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Hybrid PET/MR Imaging: Technological Advances and Multidisciplinary Clinical Applications

edited by

Marco Fogante

submission deadline 31 Dec 2025 | 1 articles | Viewed by 898 | Submission Open

Keywords: PET/MR; hybrid imaging; molecular imaging; diagnostic imaging; oncology; cardiology; neurology; senology; pediatrics; musculoskeletal imaging; precision medicine; clinical applications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Neurological Disorders: Diagnosis and Management

edited by

Lung Chan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 876 | Submission Open

Keywords: stroke diagnosis; treatment outcome prediction; neuroimaging; machine learning; biomarkers; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Head and Neck and Oral Maxillofacial Radiology

edited by

Hemis Qiyong Ai

submission deadline 31 Dec 2025 | 1 articles | Viewed by 833 | Submission Open

Keywords: medical imaging; head and neck; machine learning; radiomics analysis; medical image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostics in Focus: Accelerating Access for Priority Diseases in Africa

edited by Rosanna Peeling,

Debi Boeras

and Nicaise Ndembi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 804 | Submission Open

Keywords: diagnostics; epidemic-prone diseases; outbreak preparedness and response

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Global Perspectives on Myopia—Epidemiology, Pathophysiology, and Emerging Assessment Technologies

edited by

Ungsoo-Samuel Kim

submission deadline 31 Dec 2025 | 1 articles | Viewed by 787 | Submission Open

Keywords: myopia; diagnostic imaging; optical coherence tomography (OCT); artificial intelligence (AI); biomarkers; early detection; prevention; epidemiology; digital diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Meningitis—2nd Edition

edited by

Georgina Tzanakaki

submission deadline 31 Dec 2025 | 1 articles | Viewed by 767 | Submission Open

Keywords: bacterial meningitis; invasive meningococcal disease; molecular diagnostics; molecular typing; laboratory surveillance; molecular epidemiology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

21st Century Point-of-Care, Near-Patient and Critical Care Testing—2nd Edition

edited by

Gerald J. Kost

submission deadline 31 Dec 2025 | 1 articles | Viewed by 687 | Submission Open

Keywords: point-of-care testing; infectious diseases; early detection; emergency management; disaster readiness; prehospital diagnosis; health promotion; public health resilience

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Novel Diagnostic Approaches and Treatment of Angina and Myocardial Ischemia

edited by

Marcin Kozuch

and

Emil Julian Dąbrowski

submission deadline 31 Dec 2025 | 1 articles | Viewed by 662 | Submission Open

Keywords: ischemia; angina; chronic coronary syndromes; ANOCA; INOCA; CMD; CFR; microcirculation; scintigraphy; CMR

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Liver Diseases, Third Edition

edited by

Jeong-Ju Yoo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 643 | Submission Open

Keywords: liver diseases; fatty liver; liver cirrhosis; viral hepatitis; hepatocellular carcinoma; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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