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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Prenatal Diagnosis: From Morphological Evaluation to Genetic Testing

edited by

Antonio Pizzuti

and

Gioia Mastromoro

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1198 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound (US); fetal magnetic resonance imaging (MRI); chromosomal microarray analysis; next-generation sequencing; exome sequencing; genome sequencing; non-invasive prenatal screening; non-invasive prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Multidisciplinary Diagnostic Approaches to Infectious Pathologies in Surgical Specialties

edited by

Elena Adelina Toma

and

Octavian Enciu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1156 | Submission Open

Keywords: surgical infections; diagnostic advancements; antimicrobial resistance; molecular diagnostics; radiological imaging; microbiological assays; AI-driven diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Pathology for Forensic Diagnosis

edited by

Cristina Mondello

and Vincenzo Cianci

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1052 | Submission Open

Keywords: forensic pathology; forensic medicine; forensic radiology; forensic genetics; forensic toxicology; postmortem interval; forensic odontology; forensic entomology; forensic anthropology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances and Challenges in the Diagnosis and Treatment of Rheumatic Diseases

edited by

Anastas Batalov

Mariela Geneva-Popova

and Zgurov Batalov

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1029 | Submission Open

Keywords: rheumatology ; rheumatic diseases ; musculoskeletal ultrasound ; clinical diagnostics ; biomarkers ; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics in Maxillofacial Oncology and Trauma

edited by

Ioanna Kalaitsidou

and

Benoît Schaller

submission deadline 28 Feb 2026 | 1 articles | Viewed by 665 | Submission Open

Keywords: maxillofacial diagnostics; craniofacial trauma; oral and maxillofacial oncology; artificial intelligence in imaging; photon-counting CT (PCCT); molecular biomarkers; histopathology; radiomics; multimodal imaging; preoperative planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Computer-Aided Diagnosis and Prognosis of Diseases 2025

edited by

Kenji Suzuki

submission deadline 28 Feb 2026 | Viewed by 527 | Submission Open

Keywords: computer-aided detection and diagnosis; early detection; diagnosis; characterization and intervention; advanced imaging; quantitative imaging; image-guided therapy; personalized medicine; precision medicine; biomarkers; machine/deep learning; radiogenomics; radiomics; computational/artificial intelligence; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Trends and Future Directions in Radiotheragnostic Research: A Special Issue in Collaboration with ISRT 2025

edited by

Kalevi Kairemo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 424 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; targeted alpha therapy; PSMA; prostate cancer; neuroendocrine neoplasms; somatostatin analogs; daughter radionuclides; dosimetry; small-scale/micro-dosimetry; radiobiology; target chemistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Musculoskeletal Radiology

edited by

Jernej Vidmar

submission deadline 28 Feb 2026 | Viewed by 398 | Submission Open

Keywords: musculoskeletal radiology; high-resolution MRI; ultrasound-guided interventions; artificial intelligence in imaging; CT imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging in Cardiomyopathy

edited by

Sophie Mavrogeni

submission deadline 28 Feb 2026 | Viewed by 346 | Submission Open

Keywords: cardiomyopathy; imaging technologies; cardiac MRI; echocardiography; CT; tissue characterization; myocardial fibrosis; disease progression; diagnosis; management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovative Advances in Diagnosis Through Artificial Intelligence

edited by Jorge Mateo Sotos

submission deadline 28 Feb 2026 | Viewed by 304 | Submission Open

Keywords: artificial intelligence; medical diagnostics; predictive analytics; machine learning; deep learning; digital pathology; early disease detection; personalized medicine; smart healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Diagnosis and Management of Oral Cancer: Challenges, Advances, and Multidisciplinary Integration

edited by Eleni A. Georgakopoulou

submission deadline 28 Feb 2026 | Viewed by 303 | Submission Open

Keywords: oral cancer; early diagnosis; oral squamous cell carcinoma; artificial intelligence; oral potentially malignant disorders; multidisciplinary management; tumor board; oral pathology; misinformation; dental screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Role of Biomarkers in Alzheimer's Disease

edited by

Ram Sagar

submission deadline 28 Feb 2026 | Viewed by 279 | Submission Open

Keywords: Alzheimer's disease; biomarkers; cerebrospinal fluid proteins; MRI; amyloid imaging; early diagnosis

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence and Big Data in Digestive Healthcare

edited by Hélder Cardoso and

Miguel Mascarenhas

submission deadline 28 Feb 2026 | Viewed by 278 | Submission Open

Keywords: artificial intelligence; big data; digestive system diseases; digestive system neoplasms; electronic health records; endoscopy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Applications of Radiomics and Imaging in Oncology and Cardiovascular Diseases

edited by

Dania Cioni

submission deadline 28 Feb 2026 | Viewed by 246 | Submission Open

Keywords: oncologic imaging; cardiovascular imaging; radiomics; artificial intelligence; machine learning; deep learning; magnetic resonance imaging; computed tomography; nuclear medicine; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging in Acute Respiratory Distress Syndrome

edited by

Denise Battaglini

submission deadline 28 Feb 2026 | Viewed by 244 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); computed tomography (CT); lung ultrasound (LUS); electrical impedance tomography (EIT); positron emission tomography (PET); imaging biomarkers; quantitative imaging analysis; multimodal imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathology and Molecular Diagnosis of Vascular Diseases

edited by

Francisco S. Lozano Sánchez

and María Begoña García-Cenador

submission deadline 28 Feb 2026 | Viewed by 223 | Submission Open

Keywords: vascular pathology; molecular diagnostics; precision medicine; biomarkers; atherosclerosis; thrombosis; vascular imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Artificial Intelligence in Infectious Disease Diagnosis

edited by

Thomas Foster Scherr

submission deadline 28 Feb 2026 | Viewed by 216 | Submission Open

Keywords: infectious diseases; mobile health; machine learning; epidemiology; disease surveillance; diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Human Anatomy—2nd Edition

edited by Ji-Hyun Lee

submission deadline 28 Feb 2026 | Viewed by 194 | Submission Open

Keywords: advanced anatomy; anatomical development; anatomy for diagnostic methods; anatomy and medical technology; anatomical research innovation; anatomical history

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Application of PET/CT in Oncology

edited by

Arvin Haj-Mirzaian

and

Yousef Khazaei Monfared

submission deadline 28 Feb 2026 | Viewed by 183 | Submission Open

Keywords: PET/CT; oncology; cancer imaging; radiotracers; tumor staging; precision medicine; hybrid imaging; artificial intelligence; molecular imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Endoscopic Ultrasound: Diagnostic and Therapeutic Innovations

edited by

Andrada Seicean

submission deadline 28 Feb 2026 | Viewed by 165 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic and therapeutic innovations; minimally invasive interventions; EUS-guided tissue acquisition; advanced imaging techniques; multidisciplinary gastroenterology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Approaches for Artificial Intelligence in Neuroimaging Applications, 2nd Edition

edited by

Kwang-Sig Lee

submission deadline 28 Feb 2026 | Viewed by 149 | Submission Open

Keywords: neuroimaging; machine learning; deep learning; explainable artificial intelligence; SHAP; GradCAM; generative artificial intelligence; BERT; GPT; multi-modal reinforcement learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by

Priyanka Gokulnath

and

Michail Spanos

submission deadline 28 Feb 2026 | Viewed by 148 | Submission Open

Keywords: molecular diagnostics; cardiovascular diseases; biomarkers; individualized medicine; precision cardiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Pediatric Liver Disease: Emerging Diagnostic Biomarkers, Clinical Management, and Future Directions

edited by Wikrom W. Karnsakul

submission deadline 28 Feb 2026 | Viewed by 146 | Submission Open

Keywords: pediatric liver diseases; early and precise diagnosis; diagnostic biomarker; genetic testing; imaging modalities

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Mechanistic Insights in Arrhythmia: Implications for Diagnosis and Targeted Therapy

edited by

Radu Gabriel Vătăşescu

and

Alexandru Deaconu

submission deadline 28 Feb 2026 | Viewed by 138 | Submission Open

Keywords: arrhythmia mechanisms; personalized medicine; risk stratification; ablation therapy; cardiac mapping

Laboratory Testing in Endocrine Diseases

edited by

Aw Tar-Choon

and Chin Shern Lau

submission deadline 28 Feb 2026 | Viewed by 132 | Submission Open

Keywords: endocrine diseases; laboratory testing; clinical correlation; hormone testing; diagnosis and management

(This special issue belongs to the Section Clinical Laboratory Medicine)

Rare Cancers: Improving Diagnosis and Prognosis Through Collaborative Research

edited by Chen-Wang Chang

submission deadline 28 Feb 2026 | Viewed by 129 | Submission Open

Keywords: rare cancer; diagnosis and prognosis; biomarker; early detection; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 28 Feb 2026 | Viewed by 128 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Innovations in Resuscitation and Emergency Medicine: From Biomarkers to Point-of-Care Technologies

edited by Theodoros T. Xanthos

submission deadline 28 Feb 2026 | Viewed by 126 | Submission Open

Keywords: point-of-care ultrasound; cardiac arrest; diagnostic biomarkers; cardiac or neurological injury; time-sensitive interventions

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Precision Diagnostics in Gynecologic Health and Disease

edited by

Ayse Ayhan

submission deadline 28 Feb 2026 | Viewed by 124 | Submission Open

Keywords: gynecologic diseases; diagnostic imaging; pathology; molecular diagnostic techniques; biomarkers; artificial intelligence; endometriosis; adenomyosis; precision medicine; minimally invasive surgery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Thrombosis Diagnosis and Antithrombotic Therapy

edited by Ovidio De Filippo,

Fabrizio D’Ascenzo

and Francesco Antonio Veneziano

submission deadline 28 Feb 2026 | Viewed by 120 | Submission Open

Keywords: antithrombotic therapy; ischemic heart disease; risk stratification; personalized medicine; dual antiplatelet therapy; bleeding risk; coronary artery disease; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Emerging Diagnostic Technologies in Orthopedics: Advancing Personalized Implant Design and Therapeutics

edited by

Neil Ashwood

submission deadline 28 Feb 2026 | Viewed by 119 | Submission Open

Keywords: patient-specific implant design; advanced diagnostic technologies; computational biomechanics; surgical navigation systems; implant manufacturing; intraoperative monitoring; postoperative evaluation; biomedical engineering; clinical implant optimization; precision medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Echocardiography Diagnostics

edited by Hatem Soliman Aboumarie

submission deadline 28 Feb 2026 | Viewed by 117 | Submission Open

Keywords: echocardiography innovations; cardiac imaging advancements; strain echocardiography; 3D/4D cardiac ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostics in Oncology Research

edited by Riffat Mehboob

submission deadline 14 Mar 2026 | 1 articles | Viewed by 1846 | Submission Open

Keywords: oncology diagnostics; cancer detection; precision medicine; tumor biomarkers; digital pathology; artificial intelligence in oncology; epigenetic biomarkers; immunohistochemical biomarkers; predictive modeling; genomic profiling; transcriptome signature; PET/CT and MRI diagnostics; machine learning for cancer diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning Techniques for Medical Image Analysis

edited by

Zhuhuang Zhou

submission deadline 15 Mar 2026 | 9 articles | Viewed by 24910 | Submission Open

Keywords: deep learning; supervised learning; unsupervised learning; semi-supervised learning; self-supervised learning; generative learning; deep neural networks; convolutional neural networks; physics-informed neural networks; X-ray imaging; computed tomography (CT); magnetic resonance imaging (MRI); ultrasound imaging; ultrasound computed tomography; functional MRI; positron emission tomography (PET); single-photon emission computed tomography (SPECT); functional ultrasound imaging; image reconstruction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Research Updates in Vestibular Dysfunction: Diagnostic Breakthroughs

edited by

Jun Wang

and

Sulin Zhang

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1441 | Submission Open

Keywords: vestibular disorders; vertigo; biomarkers; molecular diagnostics; vestibular compensation; Meniere’ s disease; BPPV; vestibular migraine; PPPD; dizziness; balance

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Tools and Monitoring Strategies for Chronic Diseases: Integrating Patient-Reported Outcomes to Enhance Clinical Decision-Making

edited by Vladimir Poroch

submission deadline 25 Mar 2026 | Viewed by 112 | Submission Open

Keywords: quality of life; chronic diseases; patient-reported outcome measures; patient-reported experience measures; supportive interventions; multidisciplinary and holistic approach; symptom control; healthcare accessibility; burden of care prevention; digital health tools; palliative care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Imaging

edited by

Daniel Fried

submission deadline 31 Mar 2026 | 17 articles | Viewed by 87865 | Submission Open

Keywords: dental imaging; optical coherence tomography; ultrasound; dental MRI; dental CT; cone-beam computed tomography; optical imaging; acoustic imaging; dental radiography; panoramic radiography; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Characteristics of Headache and Diagnosis of Primary and Secondary Headache Disorders

edited by

Elena R. Lebedeva

submission deadline 31 Mar 2026 | 9 articles | Viewed by 53880 | Submission Open

Keywords: primary headache disorders; secondary headache disorders; migraine-like headache; tension-type headache; migraine; headache; characteristics of headache

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Trends in In Vitro Diagnostics Paving the Way to Next-Generation Healthcare

edited by

Sandeep K. Vashist

submission deadline 31 Mar 2026 | 8 articles | Viewed by 33005 | Submission Open

Keywords: IVDs (in vitro diagnostics); POCT (point-of-care testing); LFA (lateral flow assay); CLIA (clinical laboratory improvement amendments); multiplex assays; PCR; NGS (next-generation sequencing); AI; at-home testing; biomarkers; smart technologies

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Clinical Diagnosis and Management in Cardiology

edited by

Oskars Kalejs

submission deadline 31 Mar 2026 | 16 articles | Viewed by 27865 | Submission Open

Keywords: cardiology; heart disease; arrhythmia; myocardial infarction; angina pectoris; coronary artery disease; echocardiography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Kidney Disease: Biomarkers, Diagnosis, and Prognosis: 3rd Edition

edited by

Akito Maeshima

submission deadline 31 Mar 2026 | 5 articles | Viewed by 26300 | Submission Open

Keywords: primary/secondary glomerulonephritis; rapidly progressive glomerulonephritis; nephrotic syndrome; acute kidney injury; chronic kidney disease; diabetic nephropathy/diabetic kidney disease; chronic renal failure; kidney transplantation; renal fibrosis; polycystic kidney

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Biomedical Imaging and Signal Processing

edited by Olusola Oluwakemi Abayomi-Alli,

Olamilekan Shobayo

and

Modupe Odusami

submission deadline 31 Mar 2026 | 6 articles | Viewed by 12527 | Submission Open

Keywords: medical image processing; healthcare; artificial intelligence; machine learning; deep learning; computer vision; AI-assisted; explainable ai; segmentation; augmentation; multimodal fusion

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Diagnosis and Management in Orthopaedics and Traumatology

edited by Attilio Basile

submission deadline 31 Mar 2026 | 6 articles | Viewed by 12306 | Submission Open

Keywords: joint replacement; surgical navigation; outcome assessment; fracture repair; imaging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Oral Disorders

edited by

Jyothi Tadakamadla

submission deadline 31 Mar 2026 | 8 articles | Viewed by 12125 | Submission Open

Keywords: oral disease; biomarker; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancing Clinical Diagnosis with Artificial Intelligence: Applications, Challenges, and Future Directions

edited by

Haipeng Liu

Rajesh K. Tripathy

, Shonak Bansal and

Prince Jain

submission deadline 31 Mar 2026 | 6 articles | Viewed by 9631 | Submission Open

Keywords: deep learning; artificial intelligence (AI); internet of medical things (IoMT); AI-assisted diagnostics; multimodal clinical data; data-driven healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Insights into Perinatal Medicine and Fetal Medicine—2nd Edition

edited by Paola Quaresima and Ilaria Fantasia

submission deadline 31 Mar 2026 | 6 articles | Viewed by 8035 | Submission Open

Keywords: fetal malformations; hypertensive disorders of pregnancy; gestational diabetes; fetal growth; in utero surgery; first-trimester screening; fetal aneuploidies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Pediatric Genetics

edited by

Chunglin Lee

submission deadline 31 Mar 2026 | 6 articles | Viewed by 6982 | Submission Open

Keywords: pediatric genetics; genetic sequencing; rare disorders; genetic diagnosis; precision medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases

edited by

Francesco Giurazza

and

Fabio Corvino

submission deadline 31 Mar 2026 | 7 articles | Viewed by 6449 | Submission Open

Keywords: embolization; radial; oncology; radioembolization; ablation; chemoembolization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Cerebrovascular Lesions: Diagnosis and Management, 2nd Edition

edited by

Hung-Chieh Chen

submission deadline 31 Mar 2026 | 8 articles | Viewed by 6405 | Submission Open

Keywords: stroke; aneurysm; vascular malformation; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Gynecologic Oncology: Diagnosis and Management, 2nd Edition

edited by

Jure Knez

submission deadline 31 Mar 2026 | 3 articles | Viewed by 6190 | Submission Open

Keywords: endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; ultrasound; colposcopy; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Displaying special issue 201-250 on page 5 of 15.

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