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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Deep Learning in Biomedical Image and Signal Processing: Recent Advancements and Applications

edited by Narinder Singh Punn

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5469 | Submission Open

Keywords: deep learning; biomedical image; signal processing; multimodal data fusion; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Urinary Tract Infections: Advances in Diagnosis and Management

edited by

Paul Froom

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4951 | Submission Open

Keywords: urinary tract infections; diagnosis; management; antimicrobial therapy; urinalysis; urine culture; recurrent UTI; asymptomatic bacteriuria

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Prognosis of Hematological Disease

edited by Sapha Shibeeb

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4755 | Submission Open

Keywords: hematological diseases; leukaemia; molecular diagnostics; next-generation sequencing (NGS); precision medicine; predictive biomarkers; AI-assited diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Dental Imaging, Oral Diagnosis, and Forensic Dentistry

edited by

Anastasia Mitsea

, Christos Angelopoulos and Aliki Rontogianni

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4428 | Submission Open

Keywords: automated segmentation; neural networks in dentistry; digital intraoral scanning; radiographic/surgical guides; virtual reality in dental imaging; 3D surgical stimulation; 3D facial reconstruction; forensic odontology; forensic dentistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Treatment, and Prognosis of Breast Cancer

edited by

Marko Buta

submission deadline 31 Jan 2026 | 4 articles | Viewed by 3928 | Submission Open

Keywords: breast cancer diagnosis; molecular profiling; artificial intelligence; targeted therapy; immunotherapy; treatment strategies; prognostic markers; triple-negative breast cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Hematologic Malignancies

edited by

Ankur Varma

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3832 | Submission Open

Keywords: acute myeloid leukemia; chronic myeloid leukemia; myelodysplastic syndrome; myeloproliferative neoplasm; Hodgkin's lymphoma; non-Hodgkin's lymphoma; acute lymphocytic leukemia; chronic lymphocytic leukemia; bone marrow failure syndrome; juvenile myelomonocytic leukemia

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Laboratory Diagnosis in Microbial Diseases, 3rd Edition

edited by

Hsin-Yao Wang

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3280 | Submission Open

Keywords: genomics; proteomics; diagnostics; infections

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis, Prognosis and Management of Cardiovascular Disease in Patients with Rheumatic Conditions

edited by

Patrick H. M. C. Dessein

Miguel Angel Gonzalez-Gay

and

Iván Ferraz-Amaro

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3257 | Submission Open

Keywords: rheumatoid arthritis; rheumatic conditions; cardiovascular risk factors; atherosclerosis; left ventricular structure and function; arterial function; cardiovascular events; ischemic heart disease; ischemic stroke; heart failure; peripheral vascular disease; venous thrombotic disease; cardiovascular drugs; antirheumatic agents

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy

edited by Cristiano Spada and Daniele Salvi

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3053 | Submission Open

Keywords: gastrointestinal endoscopy; therapeutic endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); artificial intelligence; small bowel capsule endoscopy; bariatric endoscopy

(This special issue belongs to the Section Biomedical Optics)

Advances in Precision Diagnosis of Head and Neck Tumors: From Clues to Clarity

edited by

Alfio Ferlito

and

Orlando Guntinas-Lichius

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3031 | Submission Open

Keywords: head and neck cancer; screening; radiomics; human papillomavirus; liquid biopsy; de-escalation; clinical guidelines; sentinels node; quality of life

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Gastrointestinal Surgery: Diagnosis and Management in 2025

edited by

Federico Selvaggi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2861 | Submission Open

Keywords: gastrointestinal trauma; oligometastatic disease; mesorectal metastasis; lymphnode metastasis; minimally invasive surgical therapy; endoscopic diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Musculoskeletal Imaging in Clinical Practice: From Detection to Decision-Making

edited by

Seul Ki Lee

submission deadline 31 Jan 2026 | 4 articles | Viewed by 2536 | Submission Open

Keywords: musculoskeletal imaging; dual-energy CT; quantitative MRI; musculoskeletal tumors; degenerative diseases; fractures; sport injuries; spine; preoperative planning; postoperative imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Gynecological and Pediatric Imaging

edited by

Gabriele Masselli

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2060 | Submission Open

Keywords: gynecological imaging; pediatric imaging; obstetrics imaging; magnetic resonance imaging (MRI); computed tomography (CT); ultrasound; early detection; cancer; congenital anomalies; treatment response; outcome assessment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Optical Coherence Tomography in 2025

edited by

Yan Li

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2053 | Submission Open

Keywords: OCT; velocimetry; angiogram; optical coherence elastography (OCE); multimodal imaging

(This special issue belongs to the Section Biomedical Optics)

Imaging in Esophageal Squamous Cell Cancer

edited by Gad Marom

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1997 | Submission Open

Keywords: esophageal squamous cell carcinoma (ESCC); FDG-PET/CT; tumor detection; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Gynecological Cancer: Diagnosis and Screening

edited by

Daniela-Cristina Stefan

and Marius Alexandru Moga

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1734 | Submission Open

Keywords: gynaecological cancers ; diagnoses gynecological cancers ; screening gynecological cancers; global gynecological cancers ; cancer equity ; innovative approaches to gynecological cancers ; gynaecological cancers outcome ; global pathology gynecological cancers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Future of Cardiac Imaging in the Diagnosis, 2nd Edition

edited by

Grigorios Korosoglou

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1707 | Submission Open

Keywords: cardiovascular imaging; diagnosis and management; early detection; risk stratification; emerging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathogenesis and Early Diagnosis of HPV-Related Cancers and Pre-Cancers

edited by

Anna Daniela Iacobone

and

Marta Tagliabue

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1648 | Submission Open

Keywords: HPV-related cancer; molecular diagnostics; precancerous lesions; biomarkers; early detection; cervical cancer; anal cancer; oropharyngeal cancer; prognostic factors; HPV genotyping

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in the Diagnosis and Management of Respiratory Disease: From Biomarkers to Treatment Decisions

edited by

Konstantinos Kostikas

and

Athena Gogali

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1606 | Submission Open

Keywords: respiratory biologics; bronchoscopy; airways disease; exhaled biomarkers; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ultrasound in the Diagnosis and Management of Skin Diseases—2nd Edition

edited by

Joanna Czajkowska

Norbert Kiss

and Miklós Gyöngy

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1312 | Submission Open

Keywords: skin diseases; ultrasound; skin cancer; machine learning; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multimodal Cardiac Imaging: Diagnostic and Prognostic Advances

edited by

Lucia La Mura

and Ciro Santoro

submission deadline 31 Jan 2026 | Viewed by 1306 | Submission Open

Keywords: cardiovascular imaging; cardiac CT; cardiac magnetic resonance; cardiac MRI; echocardiography; multimodality cardiovascular imaging; advanced echocardiography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Opportunities in Laboratory Medicine in the Era of Genetic Testing

edited by

Fernanda De-Paris

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1304 | Submission Open

Keywords: laboratory medicine; genetic testing; molecular diagnostics; personalized medicine; clinical decision-making; infectious disease diagnosis; precision oncology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Critical Ultrasound in Newborns/Children

edited by

Jing Liu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1236 | Submission Open

Keywords: lung ultrasound; pulmonary ultrasound; point-of-care lung ultrasound; newborn infants; neonates; lung diseases; pneumonia; ventilator-associated pneumonia; respiratory distress syndrome; meconium aspiration syndrome; pulmonary hemorrhage; bronchopulmonary dysplasia; tracheobronchial pneumonia; congenital pulmonary malformation; pleural effusion; pneumothorax; pulmonary edema

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Treatment and Management of Eye Diseases, Third Edition

edited by

Simona Delia Nicoara

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1208 | Submission Open

Keywords: optical coherence tomography; artificial intelligence; gene therapy; nanotechnology; stem cells; vitreo-retinal surgery; corneal transplantation; minimally invasive glaucoma surgery; cataract surgery; retinopathy of prematurity

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Biomarkers of Urological Diseases

edited by

Martin Pejchinovski

and

Jochen Metzger

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1155 | Submission Open

Keywords: proteomics; biomarkers; diagnosis; prediction; treatment; clinical application; technical advances

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Advances in Retinal Imaging

edited by

Rodolfo Mastropasqua

and

Maria Ludovica Ruggeri

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1119 | Submission Open

Keywords: retina; vitreoretinal diseases; inherited retinal dystrophies; diabetic retinopathy; age-related macular degeneration; retinal detachment; optical coherence tomography; imaging

(This special issue belongs to the Section Biomedical Optics)

Cardiovascular Diseases: Innovations in Diagnosis and Management

edited by Hisao Hara

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1080 | Submission Open

Keywords: myocardial infarction; biomarker; prognosis; coronary risk; residual risk; prognosis prediction

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Advances in Allergy Diagnosis

edited by

Zenon Brzoza

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1067 | Submission Open

Keywords: allergic diseases; allergy diagnosis; biomarker

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Genetic Diagnosis of Rare Neurological Disorders: Advances, Challenges, and Clinical Impact

edited by

Georgia Xiromerisiou

submission deadline 31 Jan 2026 | 1 articles | Viewed by 989 | Submission Open

Keywords: rare neurological disorders; genetic diagnosis; neurogenetics; next-generation sequencing; genotype– phenotype correlation; molecular diagnostics; clinical impact; personalized medicine; translational research; undiagnosed diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Aspects of CTC Research for Basic Medicine and Clinical Application

edited by Hayao Nakanishi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 972 | Submission Open

Keywords: CTC; metastasis; mobilization; cluster heterogeneity; routine blood test; genetic analysis; CTC organoid

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diabetes Mellitus: Clinical Diagnostics and Management

edited by

Syed M. Shahid

submission deadline 31 Jan 2026 | 1 articles | Viewed by 824 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; precision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Clinical and Interventional Gastroenterology

edited by

Antonio Facciorusso

and

Eyad Gadour

submission deadline 31 Jan 2026 | 1 articles | Viewed by 747 | Submission Open

Keywords: diagnostic endoscopy; AI in gastroenterology; biomarker discovery; capsule endoscopy; confocal laser endomicroscopy; early cancer detection; functional GI disorders; molecular diagnostics; non-invasive imaging; microbiome analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Beyond the Tipping Point: Advances in the Diagnosis and Management of Acute-on-Chronic Liver Failure and End-Stage Liver Disease

edited by Jonathan Soldera

submission deadline 31 Jan 2026 | 1 articles | Viewed by 501 | Submission Open

Keywords: liver cirrhosis; hepatorenal syndrome; acute-on-chronic liver failure; liver transplan-tation; biomarkers; diagnostic imaging; artificial intelligence; inflammation media-tors; prognosis; end-stage liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Progress in Abdominal Ultrasound

edited by Andrea Boccatonda,

Antonio Corvino

and

Giulio Cocco

submission deadline 31 Jan 2026 | Viewed by 408 | Submission Open

Keywords: ultrasound; abdomen; CEUS; doppler; bowel

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Cardiovascular Diagnosis and Risk Stratification

edited by

Sonu M. M. Bhaskar

submission deadline 31 Jan 2026 | Viewed by 287 | Submission Open

Keywords: cardiovascular diseases; cardiac MRI; CT angiography; and molecular imaging; biomarker discovery; artificial intelligence and machine learning; wearable devices and mobile health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Breast Diagnostics

edited by Takouhie Catherine Maldjian, Jessica Leung, Mary M. Salvatore and Judy Yee

submission deadline 31 Jan 2026 | Viewed by 255 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; breast imaging; breast cancer; breast cancer prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Multidisciplinarity in Myeloid Neoplasms: Bridging Diagnostics and Clinical Insights

edited by Alexander Haushofer and Bernhard Strasser

submission deadline 31 Jan 2026 | Viewed by 187 | Submission Open

Keywords: acute myeloid leukemia (AML); myelodysplastic syndromes (MDS); myeloproliferative neoplasms (MPN); MDS/MPN genetic profiling; multidisciplinary collaboration; diagnostic innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiac Magnetic Resonance Imaging: Current and Future Clinical Applications

edited by

Per Lav Madsen

submission deadline 31 Jan 2026 | Viewed by 179 | Submission Open

Keywords: cardiomyopathy; cardiovascular physiology; ischemic heart disease; metabolic heart disease; stress MRI; heart failure with reduced ejection fraction; heart failure with preserved ejection fraction

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic, Predictive and Prognostic Biomarkers for Neurodegenerative Diseases

edited by

Ionica Pirici

submission deadline 31 Jan 2026 | Viewed by 179 | Submission Open

Keywords: neurodegenerative diseases; biomarkers; medical imaging; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic and Interventional Nephrology

edited by Ammar Almehmi

submission deadline 31 Jan 2026 | Viewed by 157 | Submission Open

Keywords: dialysis access; fistula; graft; stent; peritoneal catheter; drug-coated balloon; EndoAVF; dialysis; vascular access dysfunction; interventional nephrology; diagnostic imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnosis and Treatment Plan for Orthodontic and Oro-Facial Rehabilitations—2nd Edition

edited by

Antonino Lo Giudice

submission deadline 31 Jan 2026 | 1 articles | Viewed by 152 | Submission Open

Keywords: CBCT; facial scan; oral imaging; orthodontics; digital dentistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Jan 2026 | Viewed by 152 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer

edited by

Qiang Lv

and Xiao Yang

submission deadline 31 Jan 2026 | 1 articles | Viewed by 150 | Submission Open

Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Multimodal Biomarkers, AI, and Quantum Biology for Brain Diagnostics

edited by

Igor Goryanin

submission deadline 31 Jan 2026 | Viewed by 146 | Submission Open

Keywords: artificial intelligence; quantum biology; neurodiagnostics; biomarkers; neuroimaging; electrophysiology; diagnostics; brain networks

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Clinical Biochemistry, 2nd Edition

edited by Yu Chen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 142 | Submission Open

Keywords: clinical biochemistry; medical diagnosis; biomarkers; proteomic profiling; metabolomic profiling; high throughput technologies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Frontier Exploration of Multimodal Imaging in Cardiac Rheumatic and Immune Diseases

edited by

Sophie Mavrogeni

submission deadline 31 Jan 2026 | Viewed by 141 | Submission Open

Keywords: myopericarditis; valvular heart disease; coronary artery disease; vasculitis vascular stenosis; vascular aneurysm; reynard phenomenon

Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases, Second Edition

edited by

Stefano Francesco Crinò

submission deadline 31 Jan 2026 | Viewed by 131 | Submission Open

Keywords: endoscopic ultrasound; eRCP; radiomics; tissue acquisition; artificial intelligence; magnetic resonance imaging; cholangioscopy; pancreatic cancer; pancreatic cysts; hepatocellular carcinoma; cholangiocarcinoma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Imaging in the Diagnosis and Management of Skin Diseases

edited by Lehang Guo

submission deadline 31 Jan 2026 | Viewed by 127 | Submission Open

Keywords: skin diseases; ultrasound imaging; optical coherence tomography (OCT) imaging; photoacoustic imaging; reflectance confocal microscopy (RCM) imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Predictive Biomarkers in Oncology

edited by

Jun Zhang

submission deadline 31 Jan 2026 | Viewed by 127 | Submission Open

Keywords: predictive biomarkers; precision oncology; liquid biopsy; treatment response; biomarker validation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis and Management of Sports Injuries

edited by