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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases

edited by

Francesco Giurazza

and

Fabio Corvino

submission deadline 31 Oct 2025 | 5 articles | Viewed by 2660 | Submission Open

Keywords: embolization; radial; oncology; radioembolization; ablation; chemoembolization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Thoracic Diseases

edited by

Ke-Cheng Chen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2507 | Submission Open

Keywords: thoracic diseases; lung; diagnosis; treatment; lung tumor; thoracoscopy; biomarker; prognosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Prognosis of Gynecological and Obstetric Diseases

edited by

Giuseppe Gullo

and Valentina Billone

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2479 | Submission Open

Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Applications of Quantitative MRI in Neurodegenerative Disorders and Peripheral Neuropathies

edited by

Yongsheng Chen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2257 | Submission Open

Keywords: quantitative MRI; neurodegeneration; iron deposition; demyelination; remyelination; Parkinson’ s disease; multiple sclerosis; peripheral neuropathy

(This special issue belongs to the Section Medical Imaging and Theranostics)

3rd Edition: AI/ML-Based Medical Image Processing and Analysis

edited by

Ghazanfar Latif

and Jaafar Alghazo

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2086 | Submission Open

Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Powered Clinical Diagnosis and Decision-Support Systems

edited by

Hung-Sheng Shang

submission deadline 31 Oct 2025 | 3 articles | Viewed by 1956 | Submission Open

Keywords: artificial intelligence; clinical decision support system; medical diagnostics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Updates on the Diagnosis of Dental and Oral Diseases, Second Edition

edited by

Sreekanth Kumar Mallineni

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1785 | Submission Open

Keywords: clinical photographs; cone-beam computerized tomography; imaging in dentistry; micro CT; periodontal disease; pulpitis; radiographs; root canal treatment; saliva; PCR; biofilms; malocclusions; digital dentistry

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Challenges in Monitoring and Diagnosis in Medical Sciences

edited by

Mihaela Badea

and

Laura Gaman

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1551 | Submission Open

Keywords: diagnostic; monitoring; medical sciences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Insights into Emergency Medicine

edited by Evan Avraham Alpert

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1547 | Submission Open

Keywords: emergency medicine; trauma; sepsis; acute coronary syndrome; mortality

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Prognosis of Abdominal Diseases

edited by

Filippo Carannante

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1232 | Submission Open

Keywords: diagnosis; prognosis; abdominal diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Advances and Applications in Neuroradiology: 2nd Edition

edited by

Houman Sotoudeh

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1224 | Submission Open

Keywords: neuroradiology; advanced imaging; susceptibility-weighted imaging (SWI); diffusion tensor imaging (DTI); functional MRI (fMRI); CT perfusion; MR perfusion; MR spectroscopy; PET; molecular imaging; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management

edited by Ombretta Martinelli and

Antonio Marzano

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1200 | Submission Open

Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound in Renal Diseases: A Useful Tool for Diagnostics and Therapy

edited by

Caterina Carollo

submission deadline 31 Oct 2025 | 2 articles | Viewed by 998 | Submission Open

Keywords: kidney; nephrology; ultrasounds; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in the Diagnosis and Management of Gynecological Cancers

edited by Zelal M. Muallem

submission deadline 31 Oct 2025 | 1 articles | Viewed by 946 | Submission Open

Keywords: gynecological cancers; diagnosis and staging; molecular biomarkers; targeted therapies; immunotherapy; minimally invasive surgery; personalized medicine; cancer resistance; quality of life in oncology; disparities in cancer care

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management in Digestive Surgery: 2nd Edition

edited by

Valentin Calu

and Florin Grama

submission deadline 31 Oct 2025 | 1 articles | Viewed by 927 | Submission Open

Keywords: digestive diseases; novel changes in diagnosis; updates on daily practice; management of digestive diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Brain MRI: Current Development and Applications

edited by

Hung-Chieh Chen

submission deadline 31 Oct 2025 | 1 articles | Viewed by 899 | Submission Open

Keywords: neuroimaging; diagnostic MRI; artificial intelligence; neurological disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Maternal–Fetal Medicine: 2nd Edition

edited by

Elena Bernad

submission deadline 31 Oct 2025 | 2 articles | Viewed by 839 | Submission Open

Keywords: pregnancy; fetus; ultrasound; maternal– fetal medicine; perinatal care high risk; obstetrics; complication; screening; diagnostics; fetal distress

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Endocrinology Pathology

edited by

Mara Carsote

Ana Valea

and

Claudiu Nistor

submission deadline 31 Oct 2025 | 1 articles | Viewed by 743 | Submission Open

Keywords: histological classification and reporting; cytological analysis; fine-needle aspiration; molecular markers; immunohistochemistry; hormone; dynamic hormonal testing; endocrine tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition

edited by Costantino Ricci

submission deadline 31 Oct 2025 | 2 articles | Viewed by 643 | Submission Open

Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Laboratory Analysis and Diagnostics

edited by Ivana Lapić

submission deadline 31 Oct 2025 | 1 articles | Viewed by 611 | Submission Open

Keywords: laboratory analysis; diagnostics; analytical techniques; diagnostic methods

(This special issue belongs to the Section Clinical Laboratory Medicine)

Applications of Artificial Intelligence in Orthopedics

edited by Zhonghai Li

submission deadline 31 Oct 2025 | 1 articles | Viewed by 601 | Submission Open

Keywords: artificial intelligence; orthopedics; medical diagnosis; image analysis; predictive modeling

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Advances in Diagnostic Bronchoscopy

edited by

Kassem Harris

submission deadline 31 Oct 2025 | 1 articles | Viewed by 554 | Submission Open

Keywords: diagnostic bronchoscopy; advanced imaging techniques; interventional bronchoscopy; minimally invasive techniques

(This special issue belongs to the Section Biomedical Optics)

Recent Advances in Preclinical and Clinical Stroke Imaging

edited by

Tim Duong

submission deadline 31 Oct 2025 | Viewed by 541 | Submission Open

Keywords: cerebral ischemia; cerebral infarction; ischemic stroke; hemorrhagic stroke; MRI; CT; ischemic penumbra; stroke recovery

(This special issue belongs to the Section Medical Imaging and Theranostics)

Type 2 Inflammatory Disorders: From Eosinophilic Gastrointestinal Disorders (EGIDs) and Beyond

edited by Edoardo Vespa and

Alberto Barchi

submission deadline 31 Oct 2025 | Viewed by 526 | Submission Open

Keywords: eosinophilic esophagitis; EGIDs; asthma; CRSwNP; type 2 disorders; eosinophilic diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Musculoskeletal Disorders: Diagnosis, Management, and Rehabilitation, 2nd Edition

edited by

Antonio Stecco

submission deadline 31 Oct 2025 | 1 articles | Viewed by 512 | Submission Open

Keywords: musculoskeletal disorders; pain; disability; diagnosis; interventions; rehabilitation strategies; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiovascular Diseases: Advances in Echocardiography and Cardiac Computed Tomography

edited by Vasileios Kamperidis

submission deadline 31 Oct 2025 | 1 articles | Viewed by 448 | Submission Open

Keywords: heart failure; echocardiography; valvular heart disease; strain imaging; cardiac computed tomography; atherosclerosis; cardiomyopathy; 3D imaging; coronary artery disease; CT FFR; perfusion imaging; stress echocardiography; TEE

(This special issue belongs to the Section Medical Imaging and Theranostics)

Endoscopic Diagnosis and Management of Ear Disease

edited by

Chin-Kuo Chen

and

In Seok Moon

submission deadline 31 Oct 2025 | Viewed by 284 | Submission Open

Keywords: endoscopic otology; endoscopic ear surgery; ear disease diagnosis; minimally invasive surgery; otolaryngology advances; clinical case studies; surgical innovation; patient outcomes; diagnostic techniques; ear disease management; medical research in otology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Wearable Devices for Health Monitoring and Disease Diagnosis

edited by Robert LeMoyne

submission deadline 31 Oct 2025 | Viewed by 234 | Submission Open

Keywords: wearable devices; health monitoring; diagnosis; sensors; artificial intelligence

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Chronic Fatigue Syndrome: Clinical Diagnostics, Management, and Prognosis

edited by

Branislav Milovanovic

and

Eva Untersmayr

submission deadline 31 Oct 2025 | Viewed by 230 | Submission Open

Keywords: chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME); post-COVID-19 illness; post-infection syndromes; autonomic nervous system; Lyme disease; immunology; gut microbiota; chronic infection

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Coherence Tomography Angiography (OCTA): Advances and Applications in Retinal and Systemic Diseases

edited by

Daniela Bacherini

, Stanislao Rizzo and Fabrizio Giansanti

submission deadline 31 Oct 2025 | Viewed by 214 | Submission Open

Keywords: optical coherence tomography angiography; retinal and systemic diseases; diagnosis; screening; marker; prognosis

(This special issue belongs to the Section Biomedical Optics)

Photon-Counting CT in Clinical Application

edited by Philipp Gruschwitz

submission deadline 31 Oct 2025 | Viewed by 207 | Submission Open

Keywords: protocol development and optimization; spectral imaging; tissue characterization; lesion classification; benefits of special resolution; radiation dose optimization; contrast agent

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Insights into Gastrointestinal Endoscopy

edited by

Paraskevas Gkolfakis

and

Apostolis Papaefthymiou

submission deadline 31 Oct 2025 | Viewed by 192 | Submission Open

Keywords: diagnosis; prognosis; gastrointestinal endoscopy; markers; clinical practice and patient care

(This special issue belongs to the Section Biomedical Optics)

Radiology in the Third Millennium: New Patient-Centered Diagnostic Approaches

edited by

and Fabrizio Urraro

submission deadline 31 Oct 2025 | Viewed by 185 | Submission Open

Keywords: radiology; diagnostics; patient-specific imaging; AI; deep learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advancements of Molecular Biomarkers in Cancer, 2nd Edition

edited by Giuseppe Nicolò Fanelli

submission deadline 31 Oct 2025 | Viewed by 156 | Submission Open

Keywords: molecular biomarkers; cancer research; precision medicine; tumor profiling; genomic signatures; personalized oncology; biomarker discovery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ultrasound in Otolaryngology-Head and Neck Surgery

edited by

Tobias Todsen

, Enyinnaya Ofo and Mathias P. von Beckerath

submission deadline 31 Oct 2025 | Viewed by 142 | Submission Open

Keywords: head and neck ultrasound; surgeon-performed ultrasound; otolaryngology– head and neck surgery; minimally invasive procedures; ultrasound-guided interventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Non-Invasive Diagnostic Technologies for Heart Diseases

edited by Dentamaro Ilaria

submission deadline 31 Oct 2025 | Viewed by 132 | Submission Open

Keywords: transthoracic echocardiography; cardiac magnetic resonance; multimodality cardiovascular imaging; cardiac CT; transesophageal echocardiography; cardiovascular disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Pulmonary Adenocarcinoma

edited by

Cesar A. Moran

submission deadline 31 Oct 2025 | Viewed by 125 | Submission Open

Keywords: pulmonary adenocarcinoma; diagnosis; molecular testing; imaging analysis; detection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Role of AI and Radiomics in Diagnostic Oncology

edited by Laura Travascio and

Mario Leporace

submission deadline 31 Oct 2025 | Viewed by 115 | Submission Open

Keywords: artificial intelligence; pathophysiological; radiology and nuclear medicine; diagnostic imaging; diagnostic oncology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Laboratory Investigations in Nephrology

edited by

Marijn Speeckaert

submission deadline 31 Oct 2025 | Viewed by 109 | Submission Open

Keywords: nephrology; laboratory diagnostics; novel biomarkers; chronic kidney disease; renal pathology; artificial intelligence and machine learning

(This special issue belongs to the Section Clinical Laboratory Medicine)

Sports Related Musculoskeletal Disorders: Diagnosis, Treatment and Management

edited by

Jin Hyuck Lee

submission deadline 31 Oct 2025 | Viewed by 107 | Submission Open

Keywords: orthopedics; rehabilitation medicine; musculoskeletal disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Predictive Biomarkers in Breast Cancer

edited by

Giuseppina Rosaria Rita Ricciardi

and Maria Vita Sanò

submission deadline 31 Oct 2025 | Viewed by 101 | Submission Open

Keywords: breast cancer; HER2-positive; TNBC; ER+; HER2-negative; HER2-low; PD-L1; 18F-FES PET; hormonotherapy; immunotherapy; immune checkpoint inhibitors; liquid biopsy; circulating tumor cells; ctDNA; antibody drug conjugates; PARP inhibitors; CDK4/6 inhibitors; predictive biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Applications of Artificial Intelligence and Non-Invasive Electrocardiograms in Disease Diagnosis

edited by

Constantinos Bakogiannis

and Samuel L. Johnston

submission deadline 31 Oct 2025 | Viewed by 97 | Submission Open

Keywords: artificial intelligence (AI); non-invasive electrocardiogram (ECG); disease diagnosis; medical imaging analysis; machine learning; deep learning; cardiovascular diseases; pattern recognition; data analytics

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Insights into the Diagnosis of Neurological Disorders

edited by Yukai Cheng

submission deadline 31 Oct 2025 | Viewed by 93 | Submission Open

Keywords: neurological disorders; genomics; molecular biology; artificial intelligence; machine learning

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Treatment of Neurodevelopmental Disorders

edited by

Alessandra Gabellone

submission deadline 31 Oct 2025 | Viewed by 82 | Submission Open

Keywords: neurodevelopmental disorders; psychopathological; biomarkers for early diagnosis; machine learning; fMRI; EEG; MRI; eye-tracking

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis of Digestive Diseases

edited by Noriaki Manabe

submission deadline 31 Oct 2025 | Viewed by 81 | Submission Open

Keywords: diagnosis of gastrointestinal disease; functional gastrointestinal disorders; organic diseases; personalized medicine; physiological function evaluation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Neonatal Diagnostics

edited by Yogen Singh

submission deadline 31 Oct 2025 | Viewed by 81 | Submission Open

Keywords: neonatal imaging; point-of-care ultrasound (POCUS); targeted neonatal echocardiography; hemodynamic evaluation; functional MRI (fMRI); diffusion tensor imaging (DTI); genomic testing; neonatal intensive care units (NICUs)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Neurological Diseases: Novel Biomarkers for Diagnosis and Management

edited by

Costanza Maria Cristiani

submission deadline 31 Oct 2025 | Viewed by 73 | Submission Open

Keywords: biomarkers; laboratory medicine; neuroimaging; neurological diseases; treatment; management; clinical diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Computer-Aided Diagnosis in Endoscopy 2025

edited by

Chang Seok Bang

submission deadline 10 Nov 2025 | 1 articles | Viewed by 918 | Submission Open

Keywords: AI; deep learning; endoscopy; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Applications of PET/CT in Clinical Diagnostics

edited by Jasna M. Mihailovic and Partha S Choudhury

submission deadline 13 Nov 2025 | 3 articles | Viewed by 3616 | Submission Open

Keywords: F-18; fluorodeoxyglucose; PET/CT imaging; oncology; radiotracers beyond F-18 fluorodeoxyglucose; clinical diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Laboratory Diagnosis

edited by

Giuseppe Lippi

and Camilla Mattiuzzi

submission deadline 30 Nov 2025 | 11 articles | Viewed by 22551 | Submission Open

Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

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