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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Medical Imaging with AI: From Cutting-Edge Algorithms to Clinical Integration

edited by

Kyong Joon Lee

submission deadline 31 Mar 2026 | Viewed by 513 | Submission Open

Keywords: artificial intelligence; medical imaging; deep learning; computer-aided diagnosis (CADx); diagnostic imaging; clinical validation; medical image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis, Treatment and Management of Gastrointestinal Diseases

edited by

Carmen Fierbinteanu-Braticevici

submission deadline 31 Mar 2026 | 1 articles | Viewed by 436 | Submission Open

Keywords: gastrointestinal diseases; liver diseases; biomarkers in GI disease; imaging in GI diagnosis (CT; MRI; ultrasound); non-invasive diagnostic tools; GI Endoscopic procedures; treatment approaches; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Acute Kidney Injury: Diagnosis and Management

edited by

Silvia De Rosa

submission deadline 31 Mar 2026 | Viewed by 331 | Submission Open

Keywords: acute kidney injury (AKI); diagnosis; renal function; biomarkers; therapeutic strategies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Role of AI and Radiomics in Diagnostic Oncology

edited by Laura Travascio and

Mario Leporace

submission deadline 31 Mar 2026 | Viewed by 276 | Submission Open

Keywords: artificial intelligence; pathophysiological; radiology and nuclear medicine; diagnostic imaging; diagnostic oncology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Cardiology

edited by Hélder Alexandre Correia Dores

submission deadline 31 Mar 2026 | Viewed by 248 | Submission Open

Keywords: cardiology; cardiac imaging; biomarkers; artificial intelligence (AI); wearable technology; precision diagnostics; point-of-care testing

(This special issue belongs to the Section Clinical Laboratory Medicine)

Enhancements in Screening Pathways for Early Detection of Lung Cancer

edited by

Paolo Albino Ferrari

and

Antonio Maccio

submission deadline 31 Mar 2026 | Viewed by 228 | Submission Open

Keywords: lung cancer screening; early diagnosis; multidisciplinary pathways; liquid biopsy; exhaled breath condensate; molecular imaging; sub-lobar resection; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Endoscopy—A New Era in Gastrointestinal Diagnostics

edited by

Anastasios Koulaouzidis

Ervin Toth

and

Mohammed Abdulrasak

submission deadline 31 Mar 2026 | Viewed by 201 | Submission Open

Keywords: AI-supported detection; classification; and workflow in endoscopy; innovations in capsule and device-assisted endoscopy; image enhancement technologies and real-time analytics; therapeutic endoscopic advances and new instrumentation; integration of digital tools and automation into clinical practice; perspectives on training; quality; and standardization; ethical and regulatory considerations in emerging technologies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Radiology for Breast Cancer

edited by Romuald Ferré

submission deadline 31 Mar 2026 | Viewed by 198 | Submission Open

Keywords: breast cancer screening; digital breast tomosynthesis (DBT); contrast-enhanced mammography (CEM); abbreviated breast MRI; artificial intelligence and radiomics; ultrasound correlation; risk-stratified imaging pathways

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Advances in Laryngoscopy

edited by Anaïs Rameau

submission deadline 31 Mar 2026 | Viewed by 183 | Submission Open

Keywords: laryngoscopy; otolaryngology; pharyngoscopy; endoscopy; laryngeal cancer; benign laryngeal lesions; diagnostic imaging; high-definition endoscopy; three-dimensional imaging; computer-aided diagnosis

(This special issue belongs to the Section Biomedical Optics)

Breakthroughs in Advanced Medical X-Ray and CT Imaging: From Technology to Clinical Application

edited by Joyoni Dey

submission deadline 31 Mar 2026 | Viewed by 176 | Submission Open

Keywords: advanced X-ray CT imaging; X-ray CT interferometry; phase-contrast X-ray; photon-counting detectors

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Radiomics for Medical Imaging: Second Edition

edited by

Xiang Li

submission deadline 31 Mar 2026 | Viewed by 163 | Submission Open

Keywords: radiomics; PET/CT; SPECT/CT; medical imaging; cancers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Abdominal Imaging

edited by Pál Kaposi

submission deadline 31 Mar 2026 | Viewed by 159 | Submission Open

Keywords: abdominal Imaging; photon-counting spectral CT; multiparametric quantitative MRI; total-body perfusion PET/CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Musculoskeletal Tumors

edited by

Tomoki Nakamura

submission deadline 31 Mar 2026 | Viewed by 157 | Submission Open

Keywords: bone tumors; soft tissue tumors; metastatic bone tumors; diagnosis; chemotherapy; immunotherapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of PET/CT in Diagnosis and Treatment of Cancers—2nd Edition

edited by Alberto Miceli

submission deadline 31 Mar 2026 | Viewed by 153 | Submission Open

Keywords: PET/CT; 18F-FDG; cancers; diagnosis; cancer treatment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Early-Stage Lung Cancer Diagnostics

edited by

Jieke Liu

and

Zhigang Chu

submission deadline 31 Mar 2026 | Viewed by 148 | Submission Open

Keywords: early-stage lung cancer; low-dose CT screening; artificial intelligence; deep learning; radiomics; habitat imaging; early detection; precision diagnosis; risk stratification; prognosis prediction

(This special issue belongs to the Section Medical Imaging and Theranostics)

Focus on Children's Oral Health: Advances in Pediatric Dentistry and Imaging Assessments

edited by Iole Vozza

submission deadline 31 Mar 2026 | Viewed by 147 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Wearable Sensors and Artificial Intelligence for Real-Time Disease Monitoring

edited by

Wei-Chih Lien

submission deadline 31 Mar 2026 | Viewed by 145 | Submission Open

Keywords: wearable sensors; artificial intelligence; real-time monitoring; digital health; biosensors; machine learning

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnosis and Management of Thrombotic Disorders

edited by

Zhi-Chun Gu

and Dong Jia

submission deadline 31 Mar 2026 | Viewed by 145 | Submission Open

Keywords: dynamic biomarker monitoring; AI-driven decision systems; precision strategies; digital health innovations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Decoding Complexity in Traumatic Injury Diagnosis: Forensic Approaches

edited by

Alice Chiara Manetti

and

Fabio Del Duca

submission deadline 31 Mar 2026 | 1 articles | Viewed by 144 | Submission Open

Keywords: traumatology; forensic pathology; vitality; post-mortem examination; trauma diagnosis; forensic imaging; individual protections; job security; histology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Treatment of Chronic Pain, Third Edition

edited by

Ferran Cuenca-Martínez

submission deadline 31 Mar 2026 | Viewed by 141 | Submission Open

Keywords: chronic pain; pain diagnostics; pain classification; pain management; pain approach; biopsychosocial

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Oral Squamous Cell Carcinoma: Diagnostics and Management

edited by Konstantinos Paraskevopoulos and

Dimitris Tatsis

submission deadline 31 Mar 2026 | Viewed by 134 | Submission Open

Keywords: oral squamous cell carcinoma; molecular diagnostics; artificial intelligence in oncology; advanced imaging techniques; personalized medicine; immunotherapy for OSCC; targeted therapies; multidisciplinary care; genomic profiling; early detection strategies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Next-Generation Diagnostics: Innovative Technologies Shaping the Future of Infectious Disease Testing

edited by

Luis Gustavo Carvalho Pacheco

submission deadline 31 Mar 2026 | Viewed by 130 | Submission Open

Keywords: molecular diagnostics; next-generation sequencing; CRISPR; biosensing; microfluidics; nucleic acid; pathogen; antimicrobial resistance

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Imaging Research on Gastrointestinal Disorders: Second Edition

edited by

Takahiro Emoto

submission deadline 31 Mar 2026 | Viewed by 129 | Submission Open

Keywords: gastrointestinal diseases; inflammatory bowel disease; intestinal obstruction; irritable bowel syndrome; gastric cancer; signal and imaging processing; visualization techniques for the gastrointestinal tract

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Imaging in Diagnostics and Therapeutics for Wounds

edited by Thomas E. Serena

submission deadline 31 Mar 2026 | Viewed by 125 | Submission Open

Keywords: chronic wounds; wound infection; surgical site infection; diabetic foot ulcer; venous leg ulcer; pressure ulcer; medical imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis of Gynecological Cancers: 2nd Edition

edited by

Angela Santoro

and

Gian Franco Zannoni

submission deadline 31 Mar 2026 | Viewed by 124 | Submission Open

Keywords: gynecological cancers; histopathology; next-generation sequencing; liquid biopsy; theranostics; digital pathology; artificial intelligence and machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advancements in Endoscopy

edited by

Eduardo Guimarães Hourneaux De Moura

submission deadline 31 Mar 2026 | Viewed by 120 | Submission Open

Keywords: artificial intelligence (AI) in endoscopy; confocal laser endomicroscopy (CLE); endoscopic ultrasound (EUS); capsule endoscopy; early gastrointestinal cancer detection

(This special issue belongs to the Section Medical Imaging and Theranostics)

Detection and Characterization of Focal Lesions in the Solid Abdominal Organs

edited by

Gavin Low

submission deadline 31 Mar 2026 | 1 articles | Viewed by 120 | Submission Open

Keywords: diagnostic imaging ; disease diagnosis; detection or characterization ; multi-modality imaging ; morphologic and functional assessments

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Multimodal Diagnostics for Lung Diseases

edited by

Ioannis P. Tomos

submission deadline 31 Mar 2026 | Viewed by 116 | Submission Open

Keywords: interstitial lung diseases; asthma; chronic obstructive pulmonary disease; respiratory infections; biomarkers; diagnostic techniques; drug discovery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinically Integrated AI for Corneal and Ocular Surface Diseases

edited by

Mohammad Soleimani

submission deadline 31 Mar 2026 | Viewed by 112 | Submission Open

Keywords: artificial intelligence; corneal diseases; ocular surface; diagnostic imaging; clinical translation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Liquid Biopsy and Molecular Diagnostics in Neuro-Oncology

edited by Santiago Cabezas-Camarero and Juan Manuel Sepúlveda-Sánchez

submission deadline 31 Mar 2026 | Viewed by 91 | Submission Open

Keywords: liquid biopsy; biofluids; biomarkers; molecular techniques; gliomas; neuro-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosing, Treating, and Preventing Eye Diseases

edited by Ermete Giancipoli

submission deadline 16 Apr 2026 | 3 articles | Viewed by 5773 | Submission Open

Keywords: retinal disease; vitreoretinal surgery; cataract surgery; intraocular lens; cornea; glaucoma; neuro-ophthalmology; multimodal imaging; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Image Analysis and Machine Learning

edited by

Inzamam Nasir

and

Costin Teodor Streba

submission deadline 21 Apr 2026 | 5 articles | Viewed by 3541 | Submission Open

Keywords: AI-enhanced clinical imaging workflows; deep learning for disease classification and segmentation; radiomics and multi-omics integration; federated learning and privacy-preserving analytics; next-generation medical image annotation techniques; explainable AI in diagnostic imaging; high-throughput screening in digital pathology; cross-domain adaptation and transfer learning in healthcare; prognostic and predictive imaging biomarkers; clinical decision support systems using machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Prognosis and Management of Breast Cancer

edited by

Marko Spasic

submission deadline 21 Apr 2026 | 2 articles | Viewed by 1293 | Submission Open

Keywords: breast cancer; diagnostics; personalized medicine; breast surgery; individualized treatment; radiotherapy; immunotherapy; targeted therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Progress in Gynecologic Oncology

edited by

Antoni Llueca

submission deadline 21 Apr 2026 | 1 articles | Viewed by 457 | Submission Open

Keywords: gynecologic oncology; early diagnosis; molecular diagnostics; imaging techniques; artificial intelligence; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Insights in Dental Diagnostics, Biomaterials and Digital Workflow

edited by

Marina Meleșcanu Imre

and

Ana Maria Cristina Țâncu

submission deadline 21 Apr 2026 | Viewed by 161 | Submission Open

Keywords: dental diagnostics; artificial intelligence (AI); digital dentistry; biomaterials; 3D printing; intraoral scanning; CAD/CAM; digital workflow; predictive analytics; clinical innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics in the Emergency and Critical Care Medicine

edited by

Zhongheng Zhang

submission deadline 30 Apr 2026 | 16 articles | Viewed by 48047 | Submission Open

Keywords: diagnostics; emergency and critical care medicine; trauma; anesthesiology; respiratory failure; sepsis; cardiovascular disease; healthcare-associated infection prevention; end-of-life care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Diagnostic and Testing Strategies for Infectious Diseases

edited by

Fernanda De-Paris

submission deadline 30 Apr 2026 | 9 articles | Viewed by 33896 | Submission Open

Keywords: infectious diseases diagnosis; clinical laboratory techniques; molecular biology; infection control; virulence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Prognosis of Sepsis

edited by

Zhongheng Zhang

submission deadline 30 Apr 2026 | 5 articles | Viewed by 26696 | Submission Open

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging in Gastrointestinal and Liver Diseases

edited by

Ruxandra Mare

and

Ioan Sporea

submission deadline 30 Apr 2026 | 8 articles | Viewed by 20078 | Submission Open

Keywords: ultrasonography; elastography; multiparametric ultrasound; contrast-enhanced ultrasound; endoscopic ultrasound; contrast-enhanced endoscopic ultrasound; computer tomography; magnetic resonance imaging; gastrointestinal diseases; diffuse liver disease; focal liver lesions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Latest News in Digital Pathology

edited by Tahir Mahmood

submission deadline 30 Apr 2026 | 6 articles | Viewed by 17643 | Submission Open

Keywords: digital pathology; generative AI; cancer diagnosis; cancer prognosis; imaging modalities; cancer grading; artificial intelligence in pathology; histopathology; image analysis; medical imaging; vision-language models in histopathology; large language models for pathology diagnostics; multimodal AI integration in digital pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Diagnosis and Management of Musculoskeletal Disorders

edited by

Antonio Jesús Láinez-Ramos-Bossini

and Fernando Ruiz Santiago

submission deadline 30 Apr 2026 | 9 articles | Viewed by 12200 | Submission Open

Keywords: musculoskeletal disorder; radiology; interventional procedure; surgery; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in the Diagnosis and Management of Respiratory Diseases

edited by Elio Antonucci

submission deadline 30 Apr 2026 | 4 articles | Viewed by 12091 | Submission Open

Keywords: respiratory disease diagnosis; advanced diagnostic techniques; respiratory management strategies; therapeutic innovations; pulmonary pathophysiology; chronic obstructive pulmonary disease (COPD); asthma management; interstitial lung diseases; respiratory infection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Management of Sleep Disorders

edited by Rayleigh Ping Ying Chiang

submission deadline 30 Apr 2026 | 3 articles | Viewed by 10382 | Submission Open

Keywords: sleep disorders; obstructive sleep apnea; diagnosis; causes; symptoms

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Exploring the Role of Diagnostic Biochemistry, 2nd Edition

edited by Daria Pašalić and Lidija Bilic-Zulle

submission deadline 30 Apr 2026 | 4 articles | Viewed by 9926 | Submission Open

Keywords: laboratory tests in diagnosis; prognosis; monitoring; and treatment; blood biomarkers in laboratory medicine; extravascular body fluid biomarkers in laboratory medicine; novel biomarkers in clinical biochemistry; evidence-based laboratory medicine; extra analytical phases and patient safety; quality assurance and management in laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Modern Diabetes Diagnosis and Treatment Technology

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 30 Apr 2026 | 5 articles | Viewed by 8469 | Submission Open

Keywords: diabetes; complications; diagnosis; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; technology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Elastography for Applications in Rehabilitation, Physiotherapy, and Sports Sciences

edited by

Juan Antonio Valera-Calero

and

Sandra Sanchez-Jorge

submission deadline 30 Apr 2026 | 3 articles | Viewed by 7937 | Submission Open

Keywords: elastography; shear wave elastography; ultrasound imaging; physiotherapy; rehabilitation; musculoskeletal system

(This special issue belongs to the Section Medical Imaging and Theranostics)

Expanding Horizons in Fascial Diagnostics and Interventions

edited by

Stanley K. H. Lam

and Bradley Dean Fullerton

submission deadline 30 Apr 2026 | 2 articles | Viewed by 7767 | Submission Open

Keywords: ultrasound imaging; fascial pathologies; musculoskeletal function; fascial disorders; ultrasound-guided interventions; musculoskeletal care

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Role of Endoscopic Ultrasound in Clinical Medicine

edited by

Germana De Nucci

submission deadline 30 Apr 2026 | 3 articles | Viewed by 5214 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic imaging; fine needle aspiration (FNA); contrast-enhanced EUS; elastography techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Spinal Diseases

edited by Jwo-Luen Pao

submission deadline 30 Apr 2026 | 4 articles | Viewed by 5193 | Submission Open

Keywords: spinal diseases; spinal conditions; endoscopy; artificial intelligence (AI); radiological techniques; MRI; CT scans; X-rays; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Craniofacial Practices: Imaging, AI, Surgery, and Patient Care

edited by

Rami R. Hallac

submission deadline 30 Apr 2026 | 4 articles | Viewed by 4921 | Submission Open

Keywords: craniofacial imaging; 3D radiological imaging; 3D photogrammetry; 4D stereophotogrammetry; artificial intelligence (AI); craniofacial surgery; patient-centered care; 3D printing; precision medicine; telehealth; surgical planning; interdisciplinary collaboration

(This special issue belongs to the Section Medical Imaging and Theranostics)

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