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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Confocal Microscopy: Clinical Impacts and Innovation, 2nd Edition

edited by

Cleopatra Charalampaki

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1821 | Submission Open

Keywords: confocal laser endomicroscopy; diagnosis; biopsy specimens; tumor; cell imaging; deep machine learning techniques

(This special issue belongs to the Section Biomedical Optics)

Recent Advances in Diagnostic and Interventional Radiology

edited by

Serena Carriero

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1623 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; image-guided therapy; AI; minimally invasive procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Genetic and Genomic Biomarkers in Cancer Diagnosis, Prognosis, and Treatment Prediction

edited by

Jianli Dong

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1599 | Submission Open

Keywords: cancer genetics and genomics; diagnostic tests; prognostic tests; predictive tests; nucleic acid; companion diagnostics; targeted therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Management in Pediatric Urology

edited by Ioannis A. Valioulis

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1594 | Submission Open

Keywords: pediatric urology; congenital urological anomalies; minimally invasive surgery; pediatric urinary tract infections; vesicoureteral reflux; prenatal urology diagnosis; pediatric urological oncology; urinary incontinence in children; pediatric renal disorders; genitourinary reconstructive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Treatment of Cardiac Arrhythmias 2025

edited by

Fabrizio Guarracini

and

Patrizio Mazzone

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1578 | Submission Open

Keywords: atrial fibrillation; ventricular tachycardia; cardiac devices; cardiac electrophysiology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cancer Pathology and Diagnosis

edited by

Lorenzo Memeo

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1571 | Submission Open

Keywords: histopathology; histological classification; cancer biomarkers; digital pathology; AI applications; next-generation sequencing; real-time PCR

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Precision Diagnosis and Management in Kidney Transplantation

edited by

Cheng Yang

, Longshan Liu and

Marijn Speeckaert

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1396 | Submission Open

Keywords: kidney transplantation; molecular diagnosis; immune repertoire; single cell sequencing; multi-omics sequencing; radiology; ultrasound; stem cell; gene and cell therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endoscopic Diagnostics for Pancreatobiliary Disorders 2025

edited by

Masataka Kikuyama

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1282 | Submission Open

Keywords: endoscopic ultrasonography; endoscopic retrograde cholangiopancreatography; EUS– FNA; SPACE; pancreatic cancer; bile duct caner; gallbladder cancer

(This special issue belongs to the Section Biomedical Optics)

Diagnosis and Management of Colorectal Diseases

edited by

Filippo Carannante

and

Guglielmo Niccolò Piozzi

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1279 | Submission Open

Keywords: colorectal diseases; markers; diagnosis; prognosis; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI in Dermatology

edited by Jonathan Shapiro

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1136 | Submission Open

Keywords: teledermatology; artificial intelligence; AI algorithms; natural language processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Glaucoma: Diagnosis and Management

edited by

Chiara Posarelli

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1039 | Submission Open

Keywords: glaucoma; adherence; MIBS (minimally invasive bleb surgery); MIGS (microinvasive glaucoma surgery); artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Scaling Datasets, Annotations and Algorithms for Medical Image Segmentation

edited by

Zongwei Zhou

and Jeya Maria Jose

submission deadline 31 Jul 2025 | Viewed by 972 | Submission Open

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Anatomy and Diagnosis in 2025

edited by Ji-Hyun Lee

submission deadline 31 Jul 2025 | 1 articles | Viewed by 798 | Submission Open

Keywords: anatomy; advanced anatomy; anatomical development; anatomy for diagnostic methods; anatomical research innovation; mechanisms of anatomical pathogenesis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging in Esophageal Squamous Cell Cancer

edited by Gad Marom

submission deadline 31 Jul 2025 | 1 articles | Viewed by 780 | Submission Open

Keywords: esophageal squamous cell carcinoma (ESCC); FDG-PET/CT; tumor detection; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Biomedical Imaging and Signal Processing

edited by Olusola Oluwakemi Abayomi-Alli,

Olamilekan Shobayo

and

Modupe Odusami

submission deadline 31 Jul 2025 | 1 articles | Viewed by 727 | Submission Open

Keywords: medical image processing; healthcare; artificial intelligence; machine learning; deep learning; computer vision; AI-assisted; explainable ai; segmentation; augmentation; multimodal fusion

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Tool and Healthcare in Emergency Medicine

edited by

Arian Zaboli

submission deadline 31 Jul 2025 | 1 articles | Viewed by 548 | Submission Open

Keywords: emergency medicine; risk stratification; scoring systems; emergency care innovation; low-risk patient exclusion; patients safety in acute care; critical condition biomarkers; triage; decision support system

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Prostate Cancer Imaging and Biopsy Techniques

edited by Abhinav Sidana

submission deadline 31 Jul 2025 | 1 articles | Viewed by 511 | Submission Open

Keywords: multi-parametric MRI (mpMRI) of prostate; artificial intelligence and prostate MRI; PSMA PET in detection and staging of prostate cancer; novel molecular tracers for prostate cancer imaging; magnetic resonance imaging (MRI)– transrectal ultrasound (TRUS) fusion prostate biopsy; transperineal prostate biopsy; future directions regarding prebiopsy imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Biomarkers for Cardiovascular Disease

edited by

Manuela Ciocoiu

submission deadline 31 Jul 2025 | Viewed by 474 | Submission Open

Keywords: cardiovascular risk factors; hypertension; dyslipidemia; overweight; obesity; diabetes mellitus; metabolic syndrome; atherosclerosis; physical inactivity; biomarkers; cardiovascular disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endocrine System Disease: Diagnosis and Management

edited by

Kwangsoon Kim

submission deadline 31 Jul 2025 | 1 articles | Viewed by 447 | Submission Open

Keywords: endocrine system disease; hormonal imbalance; diagnosis; hormone replacement therapy; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Skin Disorders 2025

edited by Neil K. Jairath

submission deadline 31 Jul 2025 | Viewed by 409 | Submission Open

Keywords: artificial intelligence; dermatology; computer vision; machine learning; deep neural networks; large language models; personalized medicine; predictive analytics; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Markers of Genitourinary Tumors

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Jul 2025 | Viewed by 345 | Submission Open

Keywords: genitourinary tumors; diagnostic markers; biomarkers; molecular diagnostics; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence and Computational Methods in Cardiology 2025

edited by Farhad Fathieh and Guennadi Saiko

submission deadline 31 Jul 2025 | Viewed by 275 | Submission Open

Keywords: artificial intelligence in cardiology; cardiovascular diseases; diagnostics; monitoring and screening; machine/deep learning; innovative medical devices; clinical applications; multimodal medical devices

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Exploring Circadian Clock Effects on Disease Diagnosis, Progression, and Therapeutic Approaches

edited by Baharan Fekry

submission deadline 31 Jul 2025 | Viewed by 263 | Submission Open

Keywords: circadian clocks; circadian rhythm disorders; diagnosis; management

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Interventional Pulmonology

edited by Georgie A. Eapen

submission deadline 31 Jul 2025 | Viewed by 215 | Submission Open

Keywords: interventional pulmonology; minimally invasive procedures; pulmonary diagnostics; bronchoscopy; lung cancer; advanced imaging modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

Dermoscopy: Clinical Impact and Innovation

edited by

Carmen Cantisani

and

Norbert Kiss

submission deadline 31 Jul 2025 | Viewed by 204 | Submission Open

Keywords: dermoscopy; clinical impact and innovation; diagnostic; prognosis; markers

(This special issue belongs to the Section Biomedical Optics)

Molecular Mechanisms in Ophthalmology

edited by Deepshikha Tewari

submission deadline 31 Jul 2025 | Viewed by 196 | Submission Open

Keywords: ophthalmology; molecular mechanisms; cellular processes; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Radiology for Abdominal Disorders

edited by

Teruyoshi Amagai

submission deadline 31 Jul 2025 | Viewed by 196 | Submission Open

Keywords: abdominal diseases; diagnostic radiology; MRI; CT; radiomics; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Advances and Applications in Pediatric Radiology

edited by Yeon Jin Cho

submission deadline 31 Jul 2025 | Viewed by 192 | Submission Open

Keywords: pediatric radiology; artificial intelligence (AI); radiomics; quantitative imaging; radiation optimization; age-appropriate imaging; diagnostic accuracy; personalized medicine; imaging protocols; clinical outcomes

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Cardiovascular Diseases

edited by Maria Nikolaou and

Nikolaos Theodorakis

submission deadline 31 Jul 2025 | Viewed by 191 | Submission Open

Keywords: cardiovascular disease; diagnostic techniques; imaging modalities; biomarker testing; genetic screening; artificial intelligence; risk stratification; personalized treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Oral Pathology of Basic and Clinical Cancer Research

edited by

Jun-Ichi Tanuma

submission deadline 31 Jul 2025 | Viewed by 190 | Submission Open

Keywords: oral cancer; molecular pathology; tumor microenvironment (TME); immunotherapy; epigenetics; diagnosis; targeted therapy; personalized medicine; AI and image analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Computer-Aided Diagnosis and Prognosis of Diseases 2025

edited by

Kenji Suzuki

submission deadline 31 Jul 2025 | Viewed by 182 | Submission Open

Keywords: computer-aided detection and diagnosis; early detection; diagnosis; characterization and intervention; advanced imaging; quantitative imaging; image-guided therapy; personalized medicine; precision medicine; biomarkers; machine/deep learning; radiogenomics; radiomics; computational/artificial intelligence; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Gynecological Diseases in 2025

edited by

Yasushi Kotani

submission deadline 31 Jul 2025 | Viewed by 169 | Submission Open

Keywords: gynecological diseases; diagnosis; management strategies; obstetrics and gynecology; women’ s health; clinical practice guidelines; reproductive health disorders; personalized treatment approaches

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Chronic Subdural Hematoma: Diagnosis and Management, 2nd Edition

edited by

Theodosis Kalamatianos

submission deadline 31 Jul 2025 | Viewed by 162 | Submission Open

Keywords: chronic subdural hematoma; surgery; trial; biomarker; theranostics; prognosis; risk factor; imaging; therapy; outcome; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI-Enhanced Medical Imaging: A New Era in Oncology

edited by

Laurent Dercle

and

Laetitia Vercellino

submission deadline 31 Jul 2025 | Viewed by 146 | Submission Open

Keywords: AI-enhanced medical imaging; oncology; precision medicine; cancer care; image analysis; diagnostic accuracy; therapeutic planning; clinical trials; experimental validation; imaging methodologies; electromagnetic scattering; microwave imaging; combined modalities; electrical property tomography; low-frequency imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Cardiovascular Diagnosis and Risk Stratification

edited by

Sonu M. M. Bhaskar

submission deadline 31 Jul 2025 | Viewed by 136 | Submission Open

Keywords: cardiovascular diseases; cardiac MRI; CT angiography; and molecular imaging; biomarker discovery; artificial intelligence and machine learning; wearable devices and mobile health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Molecular Diagnostic Technologies

edited by Hin Fung Tsang

submission deadline 31 Jul 2025 | Viewed by 135 | Submission Open

Keywords: molecular diagnostics; advanced technologies; disease diagnosis; disease monitoring; disease management; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Oral and Maxillofacial Imaging

edited by

Jòzsef Piffkó

and

Agnes Janovszky

submission deadline 31 Jul 2025 | Viewed by 135 | Submission Open

Keywords: technological advancements; diagnostic imaging; treatment planning; clinical applications; oral and maxillofacial surgery; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Acute Kidney Injury: Diagnosis and Management

edited by

Silvia De Rosa

submission deadline 31 Jul 2025 | Viewed by 130 | Submission Open

Keywords: acute kidney injury (AKI); diagnosis; renal function; biomarkers; therapeutic strategies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Role of Biomarkers in Alzheimer's Disease

edited by

Ram Sagar

submission deadline 31 Jul 2025 | Viewed by 125 | Submission Open

Keywords: Alzheimer's disease; biomarkers; cerebrospinal fluid proteins; MRI; amyloid imaging; early diagnosis

(This special issue belongs to the Section Clinical Laboratory Medicine)

Clinical Challenges and Innovations in the Diagnosis of Age-Related Macular Degeneration: A Multidisciplinary Perspective

edited by

Dun Jack Fu

and Francesca Lamanna

submission deadline 31 Jul 2025 | Viewed by 112 | Submission Open

Keywords: age-related macular degeneration (AMD); machine learning; high-resolution optical coherence tomography (OCT); multimodal imaging; multidisciplinary approach; diagnostic challenges; serum metabolite biomarkers; complement system; histological studies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Endoscopy-Guided Diagnosis

edited by

Haruo Miwa

submission deadline 31 Jul 2025 | Viewed by 108 | Submission Open

Keywords: gastrointestinal disease; pancreatobiliary disease; magnifying endoscope; endoscopic ultrasonography; peroral cholangiopancreatography; endo-hepatology; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Pancreatic and Biliary Disorders

edited by

Mitsuru Okuno

submission deadline 31 Jul 2025 | Viewed by 108 | Submission Open

Keywords: biliary– pancreatic cancer; malignancy; benign biliary; stricture; ERCP; EUS; EUS-FNA; IgG4-related disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management of Colorectal Diseases

edited by Heidi Misteli

submission deadline 31 Jul 2025 | Viewed by 104 | Submission Open

Keywords: colorectal diseases; colorectal cancer; inflammatory bowel disease; diverticular disease; functional gastrointestinal disorders; diagnosis; biomarker

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Biomarker-Guided Advances in Diagnostic Medicine

edited by Edvīns Miklaševičs

submission deadline 31 Jul 2025 | Viewed by 85 | Submission Open

Keywords: medical genetics; hereditary cancers; biomarkers; miRNA; microbiome; omics; screening

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Novel Advances in Allergy Diagnosis

edited by

Zenon Brzoza

submission deadline 31 Jul 2025 | Viewed by 83 | Submission Open

Keywords: allergic diseases; allergy diagnosis; biomarker

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Intraoperative Neurophysiological Monitoring

edited by Alessandro Dario

submission deadline 31 Jul 2025 | Viewed by 68 | Submission Open

Keywords: intraoperative neurophysiological monitoring; eloquent areas; electrocorticography; spinal surgery; vascular neurosurgery; brain surgery; epilepsy surgery; direct cortical stimulation; direct electrical subcortical stimulation; electromyography; somatosensory evoked potential; motor evoked potentials; visual evoked potentials; brainstem auditory evoked potentials

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnosis, Treatment and Management of Eye Diseases, Third Edition

edited by

Simona Delia Nicoara

submission deadline 31 Jul 2025 | Viewed by 60 | Submission Open

Keywords: optical coherence tomography; artificial intelligence; gene therapy; nanotechnology; stem cells; vitreo-retinal surgery; corneal transplantation; minimally invasive glaucoma surgery; cataract surgery; retinopathy of prematurity

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Neuroimaging Biomarkers in the Diagnosis and Treatment of Mental Diseases, 2nd Edition

edited by Deborah A. Yurgelun-Todd, Douglas Kondo, Nicolas A Nunez, Perry Franklin Renshaw and Dost Öngür

submission deadline 25 Aug 2025 | 1 articles | Viewed by 3415 | Submission Open

Keywords: neuroimaging; biomarkers; 1H-MRS; 31P-MRS; brain spectroscopy; mood disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Perspectives in Forensic Diagnosis

edited by

Stavroula A. Papadodima

and

Laurent Martrille

submission deadline 31 Aug 2025 | 14 articles | Viewed by 29285 | Submission Open

Keywords: abuse; alcohol; autopsy; ballistics; brain injury; cause of death; drug-facilitated sexual assault; drugs; forensic anthropology; forensic clinical examination; forensic engineering; forensic entomology; forensic microbiology; forensic odontology; Forensic pathology; genetics; histopathology; identification of the body; molecular biology; multidisciplinary approach; post mortem interval; post-mortem biochemical analysis; postmortem CT; postmortem immunohistochemistry; postmortem MRI; rape; reconstruction of trauma; sepsis; toxicology; virtopsy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Abdominal Diseases: Diagnosis, Treatment and Management

edited by

Bogdan Socea

submission deadline 31 Aug 2025 | 12 articles | Viewed by 19334 | Submission Open

Keywords: abdominal diseases; abdominal surgery; diagnosis; image-guided surgery/treatment; minimally invasive techniques; laparoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

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