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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Integrative Approaches in Head and Neck Cancer Imaging

edited by

Calin G. Buzea

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2837 | Submission Open

Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Modern Diabetes Diagnosis and Treatment Technology

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2835 | Submission Open

Keywords: diabetes; complications; diagnosis; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; technology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in the Diagnostics of Dental Diseases, 2nd Edition

edited by Hakan Turkkahraman

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2803 | Submission Open

Keywords: artificial intelligence; machine learning; neural networks; dental diseases; clinical decision support systems; medical diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Trends in the Diagnosis of Gynecological and Obstetric Diseases

edited by

Razvan Socolov

and Laurentiu Pirtea

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2527 | Submission Open

Keywords: obstetrics and gynecology diagnostics; screening; artificial intelligence; test accuracy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Rare Diseases: Diagnosis and Management

edited by

Shu-Yang Zhang

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2280 | Submission Open

Keywords: rare diseases; diagnosis; treatment; management; technology; therapeutics; patient outcomes

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence Application in Cornea and External Diseases

edited by

Ali R. Djalilian

and Mohammad Soleimani

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2190 | Submission Open

Keywords: artificial intelligence; machine learning; cornea; ocular surface; ophthalmology; external eye diseases; mobile health; telemedicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Medical Imaging in Diagnosis, Prevention and Rehabilitation of Musculoskeletal Injuries

edited by

Yih-Kuen Jan

, W. Catherine Cheung and Suguna Pappu

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2065 | Submission Open

Keywords: fitting of prostheses and exoskeletons; force-based manipulations; medical imaging (e.g.; MRI; CT; ultrasound elastography); musculoskeletal pain (low-back pain and non-specific causes of chronic pain); myofascial pain syndrome; sports training; surgical scar and postoperative management; thermal and non-thermal modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI Transparency in Digital Pathology

edited by

Matteo Fraschini

and Gavino Faa

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2028 | Submission Open

Keywords: digital pathology; artificial intelligence; explainability; reproducibility; whole-slide image; feature extraction; deep learning; machine learning; image analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Radiomics in Oncology

edited by

Damiano Caruso

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1918 | Submission Open

Keywords: radiomics; oncology; artificial intelligence; precision medicine; texture analysis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

DNA Sequencing of Infectious Diseases

edited by

Edward R. B. Moore

and

Daniel Jaén Luchoro

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1769 | Submission Open

Keywords: DNA sequencing; infectious disease; diagnostics; screening; whole-genome sequencing; targeted amplicon sequencing

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Latest Advances in Ophthalmic Imaging

edited by

Slawomir Teper

and

Gawęcki Maciej

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1662 | Submission Open

Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Oral Disorders

edited by

Jyothi Tadakamadla

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1660 | Submission Open

Keywords: oral disease; biomarker; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Elastography for Applications in Rehabilitation, Physiotherapy, and Sports Sciences

edited by

Juan Antonio Valera-Calero

and

Sandra Sanchez-Jorge

submission deadline 30 Sep 2025 | 3 articles | Viewed by 1612 | Submission Open

Keywords: elastography; shear wave elastography; ultrasound imaging; physiotherapy; rehabilitation; musculoskeletal system

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Postural Disorders

edited by

Maciej Płaszewski

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1481 | Submission Open

Keywords: Scoliosis; Spinal deformity; Kyphosis; Faulty posture; Bad posture; Children; Adolescents; Adults; Screening; Prevention; Outcomes; Person-centred outcomes; Diagnostic imaging; Function; Functional tests

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advancements in the Diagnostics of Prostatitis

edited by

Alberto Trinchieri

and

Florian Wagenlehner

submission deadline 30 Sep 2025 | 3 articles | Viewed by 1406 | Submission Open

Keywords: prostatitis; diagnostics; biomarkers; microbiology; imaging technologies; MRI; ultrasound; precision medicine; inflammatory proteins; genetic markers; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Exploring the Role of Diagnostic Biochemistry, 2nd Edition

edited by Daria Pašalić and Lidija Bilic-Zulle

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1393 | Submission Open

Keywords: laboratory tests in diagnosis; prognosis; monitoring; and treatment; blood biomarkers in laboratory medicine; extravascular body fluid biomarkers in laboratory medicine; novel biomarkers in clinical biochemistry; evidence-based laboratory medicine; extra analytical phases and patient safety; quality assurance and management in laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Ophthalmic Disorders

edited by Assaf Kratz

submission deadline 30 Sep 2025 | 3 articles | Viewed by 1355 | Submission Open

Keywords: ocular diseases; early diagnosis; advanced imaging; glaucoma; age-related macular degeneration; diabetic retinopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Brain/Neuroimaging 2025

edited by Ronald Antulov

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1222 | Submission Open

Keywords: advanced neuroimaging; dual-energy CT; photon-counting CT; perfusion MRI; MRI fingerprinting; brain lesions; neurodegenerative disorders; brain imaging; diagnosis; prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Pathology and Diagnostics in Gastroenterology and Liver Diseases 2025

edited by

I-Wei Chang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 820 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; machine learning; gastroenterology; hepatology; pathology; theranostics; endoscopic image

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Use of Artificial Intelligence for the Diagnosis and Management of Hand Conditions

edited by

Ishith Seth

submission deadline 30 Sep 2025 | 1 articles | Viewed by 811 | Submission Open

Keywords: artificial intelligence; machine learning; hand conditions; preoperative diagnosis; postoperative prognosis; surgical outcomes; imaging techniques

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Breast Cancer Imaging

edited by

Tim Duong

submission deadline 30 Sep 2025 | 1 articles | Viewed by 805 | Submission Open

Keywords: breast cancer; neoadjuvant chemotherapy; axillary lymph nodes; molecular subtypes; hormonal receptor positive; medical oncology; breast surgery; breast cancer metastasis; pathological complete response; breast cancer recurrence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging in Neurological Diseases

edited by

Daniele Coraci

submission deadline 30 Sep 2025 | 3 articles | Viewed by 795 | Submission Open

Keywords: diagnostic imaging; neurological diseases/disorders; central nervous system; imaging techniques; magnetic resonance imaging (MRI); positron emission tomography (PET); diagnostic modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

Inflammatory and Infectious Skin Diseases: From Diagnostics to Management

edited by

Giulia Ciccarese

Francesca Ambrogio

and Valeria Gaspari

submission deadline 30 Sep 2025 | 1 articles | Viewed by 590 | Submission Open

Keywords: inflammatory skin diseases; infectious skin diseases; dermatological diagnostics; therapeutic management; skin infection biomarkers; immune-mediated skin disorders; clinical dermatology; precision medicine in dermatology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Epidemiology, Diagnostic Tools, and Vaccination Strategies for Emerging Infectious Diseases: Preparing for the Next Pandemic

edited by Luis Pablo Cruz-Hervert,

Maria-Eugenia Jimenez-Corona

and Renata Alejandra Báez Saldaña

submission deadline 30 Sep 2025 | Viewed by 563 | Submission Open

Keywords: emerging infectious diseases; COVID-19; influenza; epidemiological surveillance; diagnostic innovations; vaccination strategies; vaccine-preventable diseases; drug resistance; infectious disease modeling; global health preparedness

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Vulvovaginal Disorders: The Critical Role of Accurate Diagnosis to Effective Management Strategies

edited by Orna Reichman and

Jack Sobel

submission deadline 30 Sep 2025 | 1 articles | Viewed by 455 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; vulvovaginal disorders; pathology; theranostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Hepatobiliary and Pancreatic Cancer Diagnosis: Recent Developments

edited by

Susumu Hijioka

submission deadline 30 Sep 2025 | 1 articles | Viewed by 426 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; hepatobiliary and pancreatic cancer; pathology; theranostics; endoscopic image

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Classification of Diseases Using Machine Learning Algorithms: 2nd Edition

edited by

Derya Avci

submission deadline 30 Sep 2025 | 1 articles | Viewed by 357 | Submission Open

Keywords: artificial intelligence; classification of diseases; machine learning; medical image processing; deep learning; neural network; decision support systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Chronic Wounds: Diagnosis and Management

edited by

Thomas E. Serena

and Kylie Sandy-Hodgetts

submission deadline 30 Sep 2025 | Viewed by 334 | Submission Open

Keywords: chronic wound; imaging; biomarker; point-of-care techniques

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

An Update on Molecular Diagnostics in Prostate Cancer

edited by

Giuseppe Lucarelli

and

Francesco Lasorsa

submission deadline 30 Sep 2025 | Viewed by 317 | Submission Open

Keywords: imaging; molecular biomarkers; diagnosis; prognosis; risk stratification

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Musculoskeletal (MSK) Radiology

edited by Haron Obaid

submission deadline 30 Sep 2025 | Viewed by 314 | Submission Open

Keywords: musculoskeletal; MRI; synchrotron; artificial intelligence; ultrasound; robotics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Renal Cell Cancer

edited by

Giuseppe Lucarelli

submission deadline 30 Sep 2025 | Viewed by 306 | Submission Open

Keywords: renal cell carcinoma; biomarkers; nephrectomy; diagnosis; treatment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Imaging Biomarkers for Pachychoroid Spectrum Disease

edited by

Rui Hua

Feng Wen

and

Meixia Zhang

submission deadline 30 Sep 2025 | Viewed by 296 | Submission Open

Keywords: pachychoroid spectrum disease; peripapillary pachychoroid syndrome; central serous chorioretinopathy; pachychoroid neovasculopathy; polypoidal choroidal vasculopathy; pachychoroid pigment epitheliopathy; focal choroidal excavation; macular neovascularization; optical coherence tomography angiography; indocyanine green angiography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Alzheimer’s Disease Diagnosis—2nd Edition

edited by

Mohammad Shahadat Hossain

submission deadline 30 Sep 2025 | Viewed by 293 | Submission Open

Keywords: Alzheimer’ s disease; artificial intelligence; machine learning; explainable AI; expert systems; computer vision; deep learning; diagnosis; cognition; brain informatics; neurodegenerative disorder

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Insights into the Diagnosis and Prognosis of Eye Diseases

edited by

Rosa Giglio

and

Daniele Tognetto

submission deadline 30 Sep 2025 | 1 articles | Viewed by 273 | Submission Open

Keywords: diagnosis; prognosis; eye diseases; markers; clinical practice and patient care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Coronary Artery Disease: Diagnosis and Management

edited by Joost F. ter Woorst

submission deadline 30 Sep 2025 | Viewed by 271 | Submission Open

Keywords: coronary artery disease; EKG (electrocardiogram); Echo (echocardiography); CXR (chest X-ray); stress test; cardiac catheterization; CABG (coronary artery bypass graft surgery); OPCAB (off-pump coronary artery bypass); Endo-CAB; Robo-CAB; female sex

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic and Prognostic Biomarkers in Prostate Cancer

edited by Vittorio Fasulo

submission deadline 30 Sep 2025 | Viewed by 271 | Submission Open

Keywords: prostate cancer; biomarker; biopsy; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integration of Genomics and Diagnostics in AI-Driven Precision Oncology

edited by Wenjie Shi

submission deadline 30 Sep 2025 | Viewed by 262 | Submission Open

Keywords: machine learning; artificial intelligence; genomics; precision oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Biomarkers of Gynecological Cancers

edited by

Kelechi Njoku

submission deadline 30 Sep 2025 | Viewed by 242 | Submission Open

Keywords: biomarkers; gynecological cancer; cervical cancer; ovarian cancer; uterine cancer; endometrial cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Craniofacial Practices: Imaging, AI, Surgery, and Patient Care

edited by

Rami R. Hallac

submission deadline 30 Sep 2025 | Viewed by 176 | Submission Open

Keywords: craniofacial imaging; 3D radiological imaging; 3D photogrammetry; 4D stereophotogrammetry; artificial intelligence (AI); craniofacial surgery; patient-centered care; 3D printing; precision medicine; telehealth; surgical planning; interdisciplinary collaboration

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 30 Sep 2025 | Viewed by 173 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis of Sleep Disorders Using Machine Learning Approaches, 2nd Edition

edited by

Alaa Sheta

, Shyam Subramanian and

Salim R. Surani

submission deadline 30 Sep 2025 | Viewed by 155 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; sleep disorders; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in Cardiac MRI

edited by

Magalie Viallon

submission deadline 30 Sep 2025 | Viewed by 133 | Submission Open

Keywords: diagnosis; cardiac MRI; prognosis; patient care; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Optical Coherence Tomography in Non-Invasive Diagnostic Imaging

edited by

Carmen Cantisani

and

Sandra Schuh

submission deadline 30 Sep 2025 | Viewed by 112 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; optical coherence tomography; non-invasive diagnostic imaging

(This special issue belongs to the Section Biomedical Optics)

Clinical Applications of CT and MRI

edited by

Francis Zarb

submission deadline 30 Sep 2025 | Viewed by 102 | Submission Open

Keywords: CT; MRI; diagnosis; prognosis; oncology; neurology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition

edited by

Silvia Martu

Liliana-Georgeta Foia

and

Maria Alexandra Mârțu

submission deadline 30 Sep 2025 | Viewed by 97 | Submission Open

Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Lung Imaging: Highlights of Recent Research and Clinical Applications

edited by