Emerging Trends in Fluorescent Probes for Bio/Chemical Sensing

Dear Colleagues,

Fluorescent probes have emerged as powerful tools for bio/chemical sensing, owing to their high sensitivity, rapid response, operational simplicity and capability for real-time visualization. Inspired by the increasing demand for precise, selective and practical analytical methods, fluorescent sensing systems have been widely applied in the detection of ions, small molecules, reactive species, biomacromolecules, pathogens and disease-related biomarkers. In recent years, advances in molecular engineering, supramolecular chemistry, nanotechnology, nucleic acid recognition and imaging technologies have greatly expanded the structural diversity and functional scope of fluorescent probes. However, challenges remain in improving the selectivity, sensitivity, photostability, biocompatibility, signal accuracy and applicability in complex biological, environmental, food and clinical samples.

This Special Issue, entitled "Emerging Trends in Fluorescent Probes for Bio/Chemical Sensing", seeks contributions that highlight recent progress in the design, synthesis, characterization and application of fluorescent probes and fluorescence-based sensing platforms. Authors are invited to submit original research articles, communications and reviews that address innovative sensing mechanisms, advanced probe structures, multifunctional imaging strategies, portable detection technologies and practical applications in complex real-world systems. We particularly welcome studies that bridge fundamental probe chemistry with analytical performance, biological imaging, disease diagnosis, environmental monitoring, food safety and point-of-care testing.

Topics of interest for publication include, but are not limited to, the following:

• Design, synthesis and mechanistic investigation of novel fluorescent probes and fluorophores;
• Fluorescent probes for ions, small molecules, reactive species, biomacromolecules, pathogens and disease-related biomarkers;
• Advanced fluorescent probes, including ratiometric, colorimetric, near-infrared, two-photon, lifetime-based and activatable systems;
• Fluorescence-based sensing platforms involving aptamers, nucleic acids, peptides, antibodies, enzymes, nanomaterials or hybrid recognition systems;
• Fluorescent probes for cell imaging, tissue imaging, in vivo imaging, organelle imaging and imaging-guided diagnosis;
• Portable, wearable, smartphone-assisted and point-of-care fluorescence sensing devices;
• Applications of fluorescent probes in environmental monitoring, food safety, clinical diagnostics and other complex real-world samples.

Dr. Jiaheng Zhang
Dr. Kai Shi
Prof. Dr. Wuduo Zhao
Guest Editors

Manuscript Submission Information

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