Neuronal Development and Disease: From Molecular Mechanisms to Neurological Disorders—Second Edition
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Neuroscience".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 2
Special Issue Editor
2. Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal
Interests: synapse formation; local mRNA translation; local protein synthesis; neuronal cell death; excitotoxicity; neurodevelopmental disorders; microfluidics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuronal development requires the coordinated regulation of neurogenesis, neuronal migration, axon guidance, dendritic maturation, synapse formation, circuit refinement, and glial–neuronal interactions. These processes establish the structural and functional architecture of the nervous system and depend on tightly regulated molecular, genetic, cellular, and activity-dependent mechanisms. Disruption of these mechanisms can contribute to a broad spectrum of neurological conditions, including neurodevelopmental disorders, neuropsychiatric disease, and neurodegenerative disorders.
This Special Issue aims to highlight recent advances at the interface between neuronal development and disease. We welcome studies addressing how developmental pathways shape nervous system function, how their dysregulation contributes to pathology, and how mechanistic insight can inform therapeutic strategies. Contributions may include work using cellular and animal models, human iPSC-derived systems, brain organoids, advanced imaging, omics approaches, electrophysiology, and other experimental or computational platforms relevant to nervous system development and dysfunction.
We invite original research articles, reviews, and communications focusing on molecular, cellular, synaptic, circuit-level, or organismal mechanisms underlying nervous system development, function, and disease. Topics of interest include, but are not limited to, stem cell biology, neurogenesis, neuronal differentiation, axon and dendrite development, synapse formation and plasticity, glial biology, neuroinflammation, neurodevelopmental disorders, neurodegeneration, and emerging therapeutic approaches.
Dr. Ramiro Almeida
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuronal development
- neurological disorders
- neurogenesis
- neuroinflammation
- synaptic plasticity
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