Novel Insights into Molecular and Cellular Mechanisms Underlying Chronic Pain
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 30 March 2026 | Viewed by 29
Special Issue Editor
Interests: pain; pharmacology; brain
Special Issue Information
Dear Colleagues,
Chronic pain represents a major health issue and an unmet medical challenge. Despite increasing research efforts in this field, the mechanisms underlying pain and the chronification of pain remain poorly understood. Peripheral, spinal and supraspinal processes contribute to the development and maintenance of pain. Neuronal and non-neuronal factors play a pivotal role in pain signaling and its amplification, resulting in pain persistence. New insights into the mechanisms involved in pain are desperately needed in order to identify new therapeutic targets for pain management.
This Special Issue will address current knowledge gaps in relation to the cellular factors and molecular pathways involved in the pathophysiology of pain at the peripheral, spinal, and supraspinal levels and the associated sexual dimorphisms. We welcome articles exploring pain-related mechanisms and their therapeutic implications, with the goal of inspiring the development of efficient new clinical treatments.
Dr. Mariacristina Mazzitelli
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pain
- pain management
- sexual dimorphism
- neurons
- non-neuronal factors
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