Glycosylation and Glycoproteins in Human Disease

Dear Colleagues,

Glycosylation, the enzymatic addition of glycans to proteins, lipids, and RNAs, is a fundamental post-translational modification with profound implications for human health and disease. Glycoproteins, the end products of this modification, play essential roles in immune regulation, cell signaling, and protein stability. Aberrant glycosylation has been increasingly recognized as a hallmark of numerous pathological conditions, including cancer, autoimmune disorders, congenital metabolic diseases, infectious diseases, and neurodegeneration.

This Special Issue aims to highlight cutting-edge research and in-depth reviews that explore the role of glycosylation and glycoproteins in disease mechanisms, diagnostics, and therapeutic development. We welcome submissions addressing biochemical pathways, structural and functional glycomics, glycan-based biomarkers, pathogen–host interactions, and innovations in glycoengineering for drug and vaccine development.

By bringing together interdisciplinary studies from glycobiology, molecular medicine, and biotechnology, this issue seeks to advance our understanding of how glycosylation contributes to human disease and how it can be leveraged for clinical benefit. Researchers are invited to submit original research articles, reviews, and perspectives that reflect current progress and emerging trends in this rapidly evolving field.

Join us in shaping this timely and impactful collection that will serve as a valuable resource for scientists and clinicians working at the interface of glycobiology and human health.

Dr. Mana Mukherjee
Prof. Dr. Bingmei Fu
Guest Editors

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