Glycosylation and Glycoproteins in Human Disease
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 April 2026 | Viewed by 73
Special Issue Editors
Interests: carbohydrates; carbohydrate synthesis; glycobiology; posttranslational modifications; glycoproteins; glycolipids; bioorthogonal chemistry; glycan based biomarkers; carbohydrate therapeutics
Interests: the blood–brain barrier; glycocalyx; vascular permeability; vascular signaling; tumor metastasis via microcirculation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Glycosylation, the enzymatic addition of glycans to proteins, lipids, and RNAs, is a fundamental post-translational modification with profound implications for human health and disease. Glycoproteins, the end products of this modification, play essential roles in immune regulation, cell signaling, and protein stability. Aberrant glycosylation has been increasingly recognized as a hallmark of numerous pathological conditions, including cancer, autoimmune disorders, congenital metabolic diseases, infectious diseases, and neurodegeneration.
This Special Issue aims to highlight cutting-edge research and in-depth reviews that explore the role of glycosylation and glycoproteins in disease mechanisms, diagnostics, and therapeutic development. We welcome submissions addressing biochemical pathways, structural and functional glycomics, glycan-based biomarkers, pathogen–host interactions, and innovations in glycoengineering for drug and vaccine development.
By bringing together interdisciplinary studies from glycobiology, molecular medicine, and biotechnology, this issue seeks to advance our understanding of how glycosylation contributes to human disease and how it can be leveraged for clinical benefit. Researchers are invited to submit original research articles, reviews, and perspectives that reflect current progress and emerging trends in this rapidly evolving field.
Join us in shaping this timely and impactful collection that will serve as a valuable resource for scientists and clinicians working at the interface of glycobiology and human health.
Dr. Mana Mukherjee
Prof. Dr. Bingmei Fu
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- glycobiology
- glycosylation
- glycoproteins
- glycolipids
- glycan biomarkers
- congenital disorders of glycosylation (cdg)
- immune modulation
- glycan profiling
- glycoengineering
- host–pathogen interactions
- therapeutic glycoproteins
- bioorthogonal chemistry
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