Extracellular Vesicles in Disease Pathogenesis, Therapeutics and Biomarker Discovery
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Intracellular and Plasma Membranes".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 1
Special Issue Editor
Interests: Alzheimer's disease; Parkinson’s disease; NeuroHIV; substance-use disorder; extracellular vesicles; non-coding RNA
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular Vesicles (EVs) are critical mediators of intercellular communication, regulating physiological processes and contributing to disease pathogenesis by transferring proteins, lipids, and nucleic acids between cells and organs. EVs influence cellular signaling, phenotypic plasticity, and tissue homeostasis. Growing evidence highlights their involvement in diverse diseases, including cancer, neurodegeneration, metabolic disorders, and immune dysfunction.
This Special Issue will focus on the cellular and molecular mechanisms governing EV biogenesis, cargo selection, release, and uptake, as well as their functional impact on recipient cells. Additionally, this Issue will also highlight EVs harnessed as therapeutics and for biomarker discovery. We welcome original research and review articles that advance mechanistic insight into EV biology, including EV-mediated signaling pathways, EV-associated biomarkers for disease detection and monitoring, and emerging EV-based therapeutic strategies. Studies employing advanced imaging, omics technologies, and functional assays to elucidate EV biology are particularly encouraged. This collection aims to advance mechanistic understanding of extracellular vesicles and their translational potential within the scope of cellular and molecular biology.
Dr. Susmita Sil
Guest Editor
Manuscript Submission Information
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Keywords
- extracellular vesicles
- exosomes
- exomeres
- apoptotic bodies
- macrovesicles
- EV-cargoes
- EVs as biomarkers
- EVs in therapy
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