Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Allergen-Specific Immune Cell Responses
edited by and Maria G. Byazrova
submission deadline 30 Sep 2026 | Viewed by 147 | Submission Open
Keywords: allergen; allergic sensitization; allergen-specific IgE; B cells; T cells
(This special issue belongs to the Section Cellular Immunology)
Immunological Study of Islet Transplantation
edited by Wanxing Cui
submission deadline 30 Sep 2026 | Viewed by 145 | Submission Open
Keywords: islet transplantation; transplant immunology; immune rejection; immune tolerance; regulatory T cells; autoimmunity; islet encapsulation; islet preservation; cGMP cell processing; type 1 diabetes
(This special issue belongs to the Section Cellular Immunology)
Heart Development: Mechanisms, Disorders, and Translational Perspectives
edited by , Wenhui Wei and
submission deadline 30 Sep 2026 | Viewed by 142 | Submission Open
Keywords: heart development; cardiac morphogenesis; gene regulatory networks
(This special issue belongs to the Section Reproductive Cells and Development)
Advance in Glycation End-Products in Aging and Metabolic Diseases
edited by Aleksandra Twarda-Clapa
submission deadline 30 Sep 2026 | Viewed by 130 | Submission Open
Keywords: advanced glycation end-products; AGEs; AGE receptors; scavenger receptors; signalling pathways; AGE-related diseases; inflammation; aging; metabolic diseases; anti-AGE therapies
(This special issue belongs to the Section Cellular Aging)
Mitochondrial Dynamics and Quality Control in Neuromuscular Health and Disease
edited by Kai Zou
submission deadline 30 Sep 2026 | Viewed by 129 | Submission Open
Keywords: mitochondrial dynamics; mitophagy; neuromuscular disorders; axonal transport; metabolic dysfunction; neurodegeneration; skeletal muscle homeostasis; mitochondrial biogenesis; organelle crosstalk.
(This special issue belongs to the Section Mitochondria)
Cellular and Molecular Mechanisms of Aquaporins in Plants
edited by
submission deadline 30 Sep 2026 | Viewed by 124 | Submission Open
Keywords: aquaporins; plant cells; transport regulation
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Role of Reverse Transcriptase in Aging and Age-Related Disease
edited by
submission deadline 30 Sep 2026 | Viewed by 123 | Submission Open
Keywords: aging; age-related disease; reverse transcriptase; NRTI; anti-aging; DNA damage
(This special issue belongs to the Section Cellular Aging)
The Challenges and Opportunities of Mesenchymal Stromal Cells in Regenerative Medicine
edited by
submission deadline 1 Oct 2026 | 4 articles | Viewed by 4014 | Submission Open
Keywords: mesenchymal stromal cells; mesenchymal stem cells; medicinal signaling cells; multipotent stem cells; paracrine secretion; angiogenesis; immunomodulation; cell therapy; cell-free cell-based therapy; stem cell differentiation; tissue engineering
The Pivotal Role of Tumor Stem Cells in Glioblastoma: Second Edition
edited by and Silvano J. Santini
submission deadline 1 Oct 2026 | 3 articles | Viewed by 3554 | Submission Open
Keywords: glioblastoma stem cells; resistance; cancer therapy; signaling pathways; tumor microenvironment
Emerging Strategies in Osteosarcoma: Cell Biology, Biomarkers, and Immunotherapy
edited by
submission deadline 1 Oct 2026 | 1 articles | Viewed by 1114 | Submission Open
Keywords: osteosarcoma; biomarkers; immunotherapy; metastasis; resistance
(This special issue belongs to the Section Cellular Pathology)
Advances in Matrix Metalloproteinase Research for Cancer Detection and Therapy
edited by Neha Atale, Vibha Rani and
submission deadline 1 Oct 2026 | Viewed by 292 | Submission Open
Keywords: cancer; chemotherapy; EMT (epithelial to mesenchymal transition); matrix metalloproteinase; metastasis; metalloproteinase inhibitors; natural MMP inhibitors; tumor microenvironment
Human Brain Development: Insights from Experimental and Stem Cell-Based Models
edited by Nicole Amberg
submission deadline 1 Oct 2026 | Viewed by 165 | Submission Open
Keywords: progenitor cells; neurons; glia; regional identity; neurodevelopmental disorders; cerebral organoids; iPSCs
(This special issue belongs to the Section Cellular Neuroscience)
Mitochondria: Multifaceted Regulators of Cell Death
edited by Rasa Banienė and Sonata Trumbeckaite
submission deadline 10 Oct 2026 | 1 articles | Viewed by 769 | Submission Open
Keywords: mitochondria; cell death; multifaceted regulators; reactive oxygen species (ROS); cell metabolism; mitochondrial transfer
New Advances in Proteomics for Understanding Health and Disease
edited by
submission deadline 10 Oct 2026 | Viewed by 279 | Submission Open
Keywords: mass spectrometry; single-cell proteomics; plasma proteomics; systems biology; cancer biology; health and disease; precision medicine; protein networks; clinical proteomics; multi-omics integration
(This special issue belongs to the Section Cell Methods)
Latest Advances in Molecular and Cellular Mechanisms of Alzheimer's Disease in Canada submission deadline 10 Oct 2026 | Viewed by 239 | Submission Open
Keywords: Alzheimer's disease; neurodegeneration; amyloid-beta; protein aggregation; chaperone proteins; neuroinflammation; cerebrovascular system; CD2AP; blood–brain barrier; cholinergic neurons, neuronal regeneration; gut–brain axis; GSK3; BACE1; CD33 isoforms; translational neuroscience
(This special issue belongs to the Section Cellular Neuroscience)
Integrating Advanced Cellular Models in Radiation Biology: From Electromagnetic Fields to Photons and Emerging Particle Modalities
edited by and
submission deadline 10 Oct 2026 | Viewed by 233 | Submission Open
Keywords: ionizing radiation; particle radiation; electromagnetic; radiation biology; cell cultures; preclinical models
(This special issue belongs to the Section Cellular Biophysics)
The Effects of Stress on Cells and Organisms submission deadline 10 Oct 2026 | Viewed by 170 | Submission Open
Keywords: stress; biological stress; stress response; TEs activity following stress; heat-shock proteins; epigenetic control of the stress; stress granules; alteration of metabolism following stress; stress adaptation; stress-related diseases
Advances in Zebrafish Disease Models submission deadline 15 Oct 2026 | 4 articles | Viewed by 11342 | Submission Open
Keywords: zebrafish; human disease models; experimental disease models; novel drugs and therapies; organic diseases; functional disorders
Molecular and Cellular Insights into Platelet Function, 2nd Edition submission deadline 15 Oct 2026 | 5 articles | Viewed by 6603 | Submission Open
Keywords: platelet; wound healing; fibrinolysis; regeneration and tissue remodeling; angiogenesis; lymphatic development; inflammation and immunity
T Cells in Inflammation and Cancer
edited by
submission deadline 15 Oct 2026 | 2 articles | Viewed by 5855 | Submission Open
Keywords: T cell; immunity; disease; infection; cancer; inflammation; pathology; immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Cellular Mechanisms in Pregnancy and Foetal Development submission deadline 15 Oct 2026 | 3 articles | Viewed by 5212 | Submission Open
Keywords: pregnancy; fetus; reproduction; placenta; maternal; fertility; preeclampsia; fetal growth restriction; gestational diabetes; stillbirth
Gut Dysbiosis in Inflammatory Diseases
edited by Weiwei Liu
submission deadline 15 Oct 2026 | 2 articles | Viewed by 5065 | Submission Open
Keywords: gut microbiota; innate and adaptive immunity; dysbiosis; metabolism; inflammatory bowel diseases; autoimmune diseases; metabolic disorders; fecal microbiota transplantation
(This special issue belongs to the Section Cellular Pathology)
The Artificial Intelligence to the Rescue of Cancer Research submission deadline 15 Oct 2026 | 2 articles | Viewed by 3526 | Submission Open
Keywords: cancer research; artificial intelligence; personalized medicine; multi-omics data integration; AI-driven drug discovery; precision medicine
(This special issue belongs to the Section Cell Methods)
Lung Diseases: From Cellular and Molecular Mechanisms to Targeted Therapies submission deadline 15 Oct 2026 | 1 articles | Viewed by 2868 | Submission Open
Keywords: lung diseases; cellular and molecular mechanisms; targeted therapies; OMICS; single-cell sequencing
Cellular and Molecular Studies of the Adrenal Gland
edited by Wen-Jun Shen, and Salman Azhar
submission deadline 15 Oct 2026 | Viewed by 343 | Submission Open
Keywords: adrenal zonation; steroid hormones; steroidogenesis; congenital adrenal hyperplasia; hyperaldosteronism; Cushing’s syndrome
Regenerative Medicine for Bone and Dental Tissues: Biology and Applications submission deadline 15 Oct 2026 | Viewed by 135 | Submission Open
Keywords: bone regeneration; dental tissue regeneration; stem and progenitor cells; biomaterials and bioactive scaffolds; translational regenerative strategies
(This special issue belongs to the Section Tissues and Organs)
Molecular and Cellular Mechanisms of Inherited Retinal Dystrophies
edited by Rosellina Guarascio, and
submission deadline 15 Oct 2026 | Viewed by 134 | Submission Open
Keywords: retinal degeneration; photoreceptors; RPE; phototransduction; connecting cilium; retinoid cycle; protein folding; inflammation; oxidative stress; light damage
(This special issue belongs to the Section Cellular Pathology)
Age-Related Macular Degeneration (AMD): From Cellular and Molecular Mechanisms to Therapies
edited by
submission deadline 15 Oct 2026 | Viewed by 96 | Submission Open
Keywords: age‑related macular degeneration; cellular mechanism; molecular mechanism; gene therapies; neuroprotective strategies
(This special issue belongs to the Section Cellular Aging)
Advances in Skin Physiopathology
edited by Monica Ottaviani, and
submission deadline 15 Oct 2026 | Viewed by 49 | Submission Open
Keywords: dermatological diseases; skin aging; inflammation-associated skin diseases; skin cancer; skin microbiome; 3D cell models
(This special issue belongs to the Section Cellular Pathology)
Advances in Muscle Research in Health and Disease—2nd Edition
edited by
submission deadline 20 Oct 2026 | 4 articles | Viewed by 12616 | Submission Open
Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target
(This special issue belongs to the Section Tissues and Organs)
Emerging Targets and Therapeutic Potential Drugs in Tumor Progression and Therapeutic Resistance
edited by , and Yuancheng Li
submission deadline 20 Oct 2026 | 4 articles | Viewed by 10687 | Submission Open
Keywords: cancer; tumor progression; therapeutic resistance; molecular targets; tumor microenvironment; innovative therapies; targeted drug delivery; natural product
(This special issue belongs to the Section Cell Microenvironment)
Lung Cancer: Molecular Mechanisms and Therapeutic Opportunities submission deadline 20 Oct 2026 | 3 articles | Viewed by 4952 | Submission Open
Keywords: precision oncology; immunotherapy; targeted therapy; genomic characterization; biomarker; microenvironment; non-small cell lung cancer; small cell lung cancer
(This special issue belongs to the Section Cell Microenvironment)
From Energy Metabolism to Disease: The Multifaceted Roles of Mitochondria
edited by Amy H. Attaway and Saurabh Mishra
submission deadline 20 Oct 2026 | 2 articles | Viewed by 3526 | Submission Open
Keywords: mitochondrial oxidation; ROS; aging; disease
Vascular Biology: From Molecular Mechanisms to Precision Therapies
edited by Payaningal R. Somanath
submission deadline 20 Oct 2026 | 2 articles | Viewed by 2024 | Submission Open
Keywords: angiogenesis; endothelium; vascular permeability; blood–tissue barrier; organ injury
PI3K/AKT/mTOR Signaling Network in Human Health and Diseases, 3rd Edition submission deadline 20 Oct 2026 | 1 articles | Viewed by 1464 | Submission Open
Keywords: acne; ageing; Akt; Alzheimer’s disease; autophagy; autoimmunity; PI3K; mTOR; cancer; cardiovascular diseases; diabetes; growth; hamartoma; hypertrophy; inflammation; neurologic; tuberous sclerosis; systemic sclerosis; obesity; Parkinson’s disease; psoriasis; atopic dermatitis; burns/wound healing; targeted therapy; natural products; biologics
Exclusive Review Papers in 'Cellular Biophysics'
edited by
submission deadline 20 Oct 2026 | Viewed by 255 | Submission Open
Keywords: cellular biophysics; membrane biophysics; cytoskeletal dynamics; cellular mechanics; mechanotransduction; phase separation; molecular motors; bioelectricity; single-molecule techniques; computational biophysics; mechanobiology; active matter
(This special issue belongs to the Section Cellular Biophysics)
Cellular Pathophysiology of Intensive Care Unit-Acquired Muscle Dysfunction
edited by Lars Larsson
submission deadline 20 Oct 2026 | 1 articles | Viewed by 198 | Submission Open
Keywords: intensive care unit-acquired weakness; ventilator-induced diaphragm dysfunction; skeletal muscle atrophy; protein degradation; mitochondrial dysfunction; JAK-STAT signaling; oxidative stress; critical illness myopathy; autophagy; muscle proteostasis
(This special issue belongs to the Section Cellular Pathology)
New Advances and Perspectives in the Molecular Mechanisms of Aging and Skin Cancer: Potential Options for Prevention and Treatment
edited by and Ewelina Musielak
submission deadline 20 Oct 2026 | Viewed by 111 | Submission Open
Keywords: skin cancer; malignancy; melanoma; non-melanoma; prevention; skin aging; skin photo-aging; skin inflammation; treatment; inflammaging; immune dysfunction; senescent cell
(This special issue belongs to the Section Cellular Aging)
Polyadenylation-Mediated Regulation of Pulmonary Diseases submission deadline 20 Oct 2026 | Viewed by 91 | Submission Open
Keywords: polyadenylation; lung remodeling; pulmonary fibrosis; epitranscriptomics; alveolar epithelial cells
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Regulatory Factors and Signaling Pathways of Anti-Tumor Immune Responses
edited by
submission deadline 22 Oct 2026 | 1 articles | Viewed by 758 | Submission Open
Keywords: anti-tumor immunity; immunotherapy; immune checkpoint blockade; immune receptor and ligand; immune evasion; tumor immune microenvironment; inflammation; T-cell activation and inhibition; myeloid-derived suppressor cell; macrophage; dendritic cell
(This special issue belongs to the Section Cellular Immunology)
The Dual Role of Extracellular Vesicles in Neurodegeneration: Disease Biomarkers and Drug Delivery Platforms Within the Matrix Microenvironment submission deadline 25 Oct 2026 | 1 articles | Viewed by 787 | Submission Open
Keywords: extracellular vesicles; neurodegenerative diseases; extracellular matrix; biomarkers; therapeutic applications; drug delivery
(This special issue belongs to the Section Intracellular and Plasma Membranes)
Caveolae Function in Cell Membrane Dynamics and Signal Transduction submission deadline 25 Oct 2026 | Viewed by 339 | Submission Open
Keywords: caveolae; caveolin and cavin proteins; plasma membrane organization; endocytosis and vesicular trafficking; mechanotransduction; lipid rafts and cholesterol metabolism; signal transduction; vascular biology and angiogenesis; cancer cell biology; membrane remodeling in disease
Vascular Microenvironment and Atherosclerosis submission deadline 25 Oct 2026 | Viewed by 157 | Submission Open
Keywords: vascular microenvironment; atherosclerosis; vascular inflammation; endothelial cells; smooth muscle cells; vascular–immune cell interactions; extracellular matrix; vascular remodeling; mechanotransduction; vascular biology
(This special issue belongs to the Section Cells of the Cardiovascular System)
Tumor Microenvironment and Immune Regulation
edited by
submission deadline 25 Oct 2026 | Viewed by 124 | Submission Open
Keywords: cellular immunology; tumor microenvironment; intra- and extracellular signaling; immunometabolism; experimental cytology; tumor-infiltrating lymphocytes; spatial transcriptomics
(This special issue belongs to the Section Cell Microenvironment)
Nuclear Receptors, Drug Discovery, Nutraceuticals, and Neurodegenerative Diseases
edited by Rajesh Haresh Amin, and Meenakshi Singh
submission deadline 25 Oct 2026 | Viewed by 113 | Submission Open
Keywords: nuclear receptors; neurodegenerative diseases; metabolic dysfunction; inflammation; drug design
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Advances in Annexin Biology
edited by , and Nunzia Novizio
submission deadline 28 Oct 2026 | 1 articles | Viewed by 1181 | Submission Open
Keywords: annexin family; calcium-dependent membrane binding; cell signaling; inflammation and immune response; membrane repair; cancer biology; cell motility; cell differentiation; tumor microenvironment; diagnostic/prognostic biomarkers; therapeutic targets
Role of Thyroid Hormone in Neurodegenerative and Neurodevelopmental Disorders
edited by Janaína Sena de Souza
submission deadline 30 Oct 2026 | 6 articles | Viewed by 17168 | Submission Open
Keywords: thyroid hormones; neurodevelopmental and neurodegenerative disorders; central nervous system
(This special issue belongs to the Section Cellular Neuroscience)
Advances in Reproductive Biology: Cellular and Molecular Mechanisms
edited by and Clara González-Marín
submission deadline 30 Oct 2026 | 6 articles | Viewed by 10327 | Submission Open
Keywords: gametogenesis; fertilization; embryo implantation; reproductive genetics; epigenetics in reproduction; hormonal signaling; stem cells and reproduction; assisted reproductive technologies (ARTs); molecular fertility regulation; reproductive health innovations
(This special issue belongs to the Section Reproductive Cells and Development)
Identifying Functional Genomics and Pathways in Cancer Pathogenesis and Therapy Resistance
edited by and Ramkrishna Mitra
submission deadline 30 Oct 2026 | 3 articles | Viewed by 7222 | Submission Open
Keywords: functional genomics; cancer signaling pathways; targeted therapy; drug resistance; tumor microenvironment; oncogenomics; acquired resistance; tumor mutations
(This special issue belongs to the Section Cellular Pathology)
Translational Aspects of Cell Signaling
edited by
submission deadline 30 Oct 2026 | 4 articles | Viewed by 5798 | Submission Open
Keywords: cell signaling; drug development; prognostic markers; bioinformatics; translational research
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