New Advances and Perspectives in the Molecular Mechanisms of Aging and Skin Cancer: Potential Options for Prevention and Treatment
A Special Issue of Cells (ISSN 2073-4409) belonging to the section "Cellular Aging".
Deadline for manuscript submissions: 20 October 2026 | Viewed by 167
Editors
Interests: aging; cancer; cell cycle; cell death; cell senescence; cell signaling; oncogenes; tumor suppressors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The skin, as the body’s largest organ, serves as the primary barrier protecting against environmental factors, especially pathogens. Despite its durability and high resistance, the skin is exposed to various external factors. One of the most serious threats to skin cells is ultraviolet (UV) radiation from sunlight. Prolonged sun exposure causes photoaging and mutagenesis of keratinocytes and melanocytes. Continued exposure to UV radiation can lead to DNA damage in skin cells, especially in the epidermis, where actively dividing keratinocytes are particularly vulnerable. Further skin damage and continued exposure to various factors can lead to the development of skin cancer, which remains a serious public health problem. Skin cancer encompasses a wide range of benign and malignant tumors that are common worldwide and occur more frequently than many other types of cancer. This condition is associated with the proliferation of neoplastic cells and tissues in the skin and can be associated with significant morbidity and mortality. Advanced studies using cell lines, primary cells, and animal models can utilize techniques such as qRT-PCR, Western blotting, nutrigenomics, proteomics, phosphoproteomics, and lipidomics to uncover the role of new biomarkers or anti-aging and anti-cancer agents.
The aim of this Special Issue is to investigate the complex mechanisms of skin aging and carcinogenesis and to discover innovative methods to prevent and mitigate these processes. We encourage research focused on elucidating novel mechanisms responsible for skin carcinogenesis and aging, offering new insights into the biological processes involved. By fostering a deeper understanding of these processes and identifying effective interventions, this Special Issue aims to contribute to the development of more effective skin care solutions. We encourage submissions of original research articles and reviews for this Special Issue.
Dr. Goberdhan P. Dimri
Dr. Ewelina Musielak
Guest Editors
Manuscript Submission Information
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Keywords
- skin cancer
- malignancy
- melanoma
- non-melanoma
- prevention
- skin aging
- skin photo-aging
- skin inflammation
- treatment
- inflammaging
- immune dysfunction
- senescent cell
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