Gut Dysbiosis in Inflammatory Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 15 July 2025 | Viewed by 274
Special Issue Editor
Special Issue Information
Dear Colleagues,
The gut microbiota plays a crucial role in the immune system and has significant implications for inflammatory diseases. The gut microbiota is a complex ecosystem that interacts intricately with the immune system. The gut microbiota helps inform the immune system, promoting the development of both innate and adaptive immunity. Dysbiosis, or an imbalance in gut bacteria, has been linked to autoimmune diseases like rheumatoid arthritis and multiple sclerosis, inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis, and metabolic disorders like obesity and type 2 diabetes. The gut microbiota is a complex and dynamic ecosystem, and several unsolved questions continue to intrigue researchers. For example, to what extent do specific gut microbiota compositions cause health issues, and how much are they merely correlated with inflammatory diseases? How exactly do gut microbes interact with the host’s immune system and metabolism? How do changes in diet, lifestyle, and environment affect the microbiota over time, and what are the long-term implications for health? How does the gut microbiota influence brain health and behavior? What are the mechanisms behind this gut–brain communication? What are the long-term effects and best practices for fecal microbiota transplantation? How can we tailor microbiome-based therapies for individual patients? What are the best ways to assess a person’s microbiota for personalized treatment? These questions highlight the need for continued research to deepen our understanding of the gut microbiome and its implications for health and disease.
The purpose of this Special Issue is to highlight recent findings regarding how gut microbiota interacts with the immune system and its association with various inflammatory diseases. The goal of this Special Issue is to provide a broad scope that would include research papers and reviews related to specific interactions between gut microbiota and innate and adaptive immunity, as well factors linked to dysbiosis, gut–host organ communication, directly or indirectly affecting inflammatory diseases.
Dr. Weiwei Liu
Guest Editor
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Keywords
- gut microbiota
- innate and adaptive immunity
- dysbiosis
- metabolism
- inflammatory bowel diseases
- autoimmune diseases
- metabolic disorders
- fecal microbiota transplantation
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