The Pivotal Role of Tumor Stem Cells in Glioblastoma: Second Edition
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 28 February 2026 | Viewed by 17
Special Issue Editors
Interests: inflammation; glioma; cancer stem cells; tumor biology; cyclooxygenase-2; nitric oxide synthase 2
Special Issues, Collections and Topics in MDPI journals
Interests: dicarbonyl stress; oxidative stress; mitochondrial metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are delighted to announce the launch of a Special Issue of Cells on all aspects related to the theme of “The Pivotal Role of Tumor Stem Cells in Glioblastoma: Second Edition”. We invite you to contribute original research articles or reviews to share your cutting-edge research, insights, and innovation on new mechanistic, functional, cellular, biochemical, or general evidence of cancer stem cells in glioblastoma.
Glioblastoma is one of the most complex, fast-growing, aggressive, and treatment-resistant cancers with an extremely poor prognosis. The latest therapeutic approaches are often ineffective due to the presence of glioblastoma stem cells (GSCs), which play a crucial role in resistance and recurrence.
GSCs can also significantly impact the tumor microenvironment, influencing the fate of all neighboring resident cells through genetic reprogramming and inducing key stemness features. The precise molecular mechanisms underlying the intricate scenario of GSC are not yet fully understood. A deeper understanding of the GSCs' molecular and biological features could certainly enable us to define new, targeted, and more effective therapeutic approaches to overcome cancer resistance, thereby improving survival rates and treatment responses.
Dr. Paola Palumbo
Dr. Silvano J. Santini
Guest Editors
Manuscript Submission Information
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Keywords
- glioblastoma stem cells
- resistance
- cancer therapy
- signaling pathways
- tumor microenvironment
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Related Special Issue
- The Pivotal Role of Tumor Stem Cells in Glioblastoma in Cells (7 articles)
