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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cell Migration and Invasion in Cancer
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 6953 | Submission Open
Keywords: cell migration; invasion; tumor; metastasis; genes; microRNA
(This special issue belongs to the Section Molecular Cancer Biology)
Radiation Exposure, Inflammation and Cancers
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 4282 | Submission Open
Keywords: radiation; DNA damage response; inflammation; oxidative stress; senescence and cancer
(This special issue belongs to the Section Tumor Microenvironment)
Ultrasonography for Pancreatobiliary Cancer
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1695 | Submission Open
Keywords: endoscopic ultrasonography; abdominal ultrasonography; early diagnosis project; screening; EUS-FNA; interventional EUS; enhancement EUS; EUS-RFA
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Protein Kinases and Their Impact on Tumor Growth: Mechanisms and Therapeutic Targets submission deadline 20 Aug 2025 | 1 articles | Viewed by 1245 | Submission Open
Keywords: protein kinases; PI3K-Akt signaling; MAPK signaling; kinase inhibitors; drug resistance; crosstalk
(This special issue belongs to the Section Methods and Technologies Development)
Research on New Drugs and Drug Targets in Melanoma submission deadline 20 Aug 2025 | 1 articles | Viewed by 1229 | Submission Open
Keywords: melanoma; new drugs; drug targets; mechanism of action; substances with anti-melanoma potential
(This special issue belongs to the Section Cancer Drug Development)
Exploring Non-Coding RNA Signatures in Cancer: Definitions and Implications for Diagnosis and Therapy
edited by and Udhayakumar Gopal
submission deadline 20 Aug 2025 | 1 articles | Viewed by 774 | Submission Open
Keywords: non-coding RNA; biomarkers; gene regulation; microRNA; long non-coding RNA; circular RNA; therapeutic targets
(This special issue belongs to the Section Cancer Therapy)
New Insights into Esophageal Cancer Chemotherapy
edited by Kenneth Meredith
submission deadline 20 Aug 2025 | Viewed by 364 | Submission Open
Keywords: esophageal cancer; chemotherapy; treatment
(This special issue belongs to the Section Cancer Therapy)
Novel Insights into Microenvironment of Leukemia submission deadline 20 Aug 2025 | Viewed by 187 | Submission Open
Keywords: stromal microenvironment; genetic and epigenetic alterations; bone marrow; chronic and acute leukemia; hematological malignancies
(This special issue belongs to the Section Tumor Microenvironment)
Clinical Advances and State-of-Art Management in Genitourinary Cancers
edited by and Adnan Fazili
submission deadline 25 Aug 2025 | 1 articles | Viewed by 1778 | Submission Open
Keywords: genitourinary malignancies; tumor– immune microenvironment (TIME); tumor biology; genomic characterization; targeted drug therapy; immunotherapy
(This special issue belongs to the Section Clinical Research of Cancer)
Surgical Treatment of Bone Metastases: 2nd Edition submission deadline 29 Aug 2025 | 2 articles | Viewed by 3365 | Submission Open
Keywords: metastatic bone disease; bone metastasis; pathological fractures; surgical treatment; patients survival; implant survival; functional results; surgical technique
(This special issue belongs to the Section Cancer Therapy)
New Challenges in Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia
edited by Federico Mosna and Irene Cavattoni
submission deadline 29 Aug 2025 | 1 articles | Viewed by 967 | Submission Open
Keywords: acute myeloid leukemia (AML); allogeneic hematopoietic stem cells transplantation (allo-HSCT); immunotherapy; leukemic stem cells; graft versus host disease (GVHD); infections in immunodepressed patients; immune reconstitution; post-transplant management; long-term results; clinical
(This special issue belongs to the Section Cancer Therapy)
CRISPR in Cancer Biology and Therapy: 2nd Edition
edited by
submission deadline 29 Aug 2025 | Viewed by 241 | Submission Open
Keywords: cancer drug resistance; CRISPR screens; CRISPR-related technology; base editing; prime editing; off-target analysis; adeno-associated virus
(This special issue belongs to the Section Methods and Technologies Development)
Modern Approach to Oral Cancer submission deadline 30 Aug 2025 | 11 articles | Viewed by 31160 | Submission Open
Keywords: oral cancer; neoplasm; oral surgery oncogenesis; dentistry oral health
(This special issue belongs to the Section Cancer Therapy)
Advances in Drug Repurposing to Overcome Cancers
edited by
submission deadline 30 Aug 2025 | 5 articles | Viewed by 10579 | Submission Open
Keywords: drug development; drug repurposing; drug resistance; pharmacological; cancers therapy
(This special issue belongs to the Section Cancer Drug Development)
Advances in Lung Ultrasound in Cancer Patients
edited by Helmut Prosch and
submission deadline 30 Aug 2025 | 3 articles | Viewed by 2570 | Submission Open
Keywords: lung ultrasound; neoplastic pleuro-pulmonary lesions; lung cancer; oncologic imaging; ultrasound; CEUS; elastography
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Tumor Vascular Imaging
edited by
submission deadline 30 Aug 2025 | 1 articles | Viewed by 2143 | Submission Open
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Pathology of Acute Myeloid Leukemia (AML)
edited by Olga K. Weinberg
submission deadline 30 Aug 2025 | Viewed by 1135 | Submission Open
(This special issue belongs to the Section Cancer Pathophysiology)
Breast Cancer Biomarkers and Clinical Translation: 2nd Edition
edited by and Carmine De Angelis
submission deadline 30 Aug 2025 | 1 articles | Viewed by 678 | Submission Open
Keywords: breast cancer diagnosis; cancer risk; cell reprogramming; biomarkers; resistance; precision therapy
(This special issue belongs to the Section Clinical Research of Cancer)
Chemo-Radio-Immunotherapy for Colorectal Cancer
edited by Shoichi Hazama
submission deadline 30 Aug 2025 | Viewed by 209 | Submission Open
Keywords: colorectal cancer; immunotherapy; chemotherapy; radiotherapy; combination therapy; neoadjuvant therapy; biomarkers for treatment response; anal cancer; squamous cell carcinoma; minimally invasive surgery; conversion surgery
(This special issue belongs to the Section Cancer Therapy)
Surgical Treatment of Oral Squamous Cell Carcinoma
edited by Kai-Ping Chang and Huang-Kai Kao
submission deadline 30 Aug 2025 | Viewed by 179 | Submission Open
Keywords: oral cavity; squamous cell carcinoma; OSCC; surgery; head and neck; resection; reconstruction; oncology
(This special issue belongs to the Section Clinical Research of Cancer)
Oncology: State-of-the-Art Research in Germany submission deadline 31 Aug 2025 | 26 articles | Viewed by 50193 | Submission Open
Keywords: cancer; oncology; research; Germany; cancer care
New Concepts and Recent Advances in the Management of Skin Cancer submission deadline 31 Aug 2025 | 12 articles | Viewed by 30383 | Submission Open
Keywords: skin cancer; basal cell carcinoma; cutaneous squamous cell carcinoma; melanoma; Merkel cell carcinoma; cutaneous sarcomas; treatment; checkpoint inhibitors; epidemiology; dermatologic surgery; extramammary paget's disease; cutaneous lymphoma
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Thoracic Oncology: A Multi-disciplinary Approach to Lung Cancer
edited by Percy Lee, Jyoti Malhotra and
submission deadline 31 Aug 2025 | 9 articles | Viewed by 22317 | Submission Open
Keywords: small cell lung cancer (SCLC); non-small cell lung cancer (NSCLC); thoracic radiotherapy; neoadjuvant therapies; oligometastatic disease; targeted therapy; immunotherapy; unresectable stage III NSCLC; brain-directed radiation therapy small cell lung cancer (SCLC); non-small cell lung cancer (NSCLC); thoracic radiotherapy; neoadjuvant therapies; oligometastatic disease; targeted therapy; immunotherapy; unresectable stage III NSCLC; brain-directed radiation therapy
(This special issue belongs to the Section Clinical Research of Cancer)
Gastrointestinal Malignancy: Epidemiology and Risk Factors
edited by Patrick Okolo and Chengu Niu
submission deadline 31 Aug 2025 | 5 articles | Viewed by 18698 | Submission Open
Keywords: gastrointestinal cancer; epidemiology; risk factors; molecular markers; genetic factors; therapeutic advancements; prevention strategies; public health; interdisciplinary approaches; clinical impact
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Cutaneous Lymphoma
edited by Michi M. Shinohara
submission deadline 31 Aug 2025 | 6 articles | Viewed by 18142 | Submission Open
Keywords: primary cutaneous lymphoma; cutaneous T-cell lymphoma; mycosis fungoides; Sé zary syndrome; health-related quality of life
(This special issue belongs to the Section Molecular Cancer Biology)
Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes
edited by Petros I. Bangeas and Vasileios N. Papadopoulos
submission deadline 31 Aug 2025 | 4 articles | Viewed by 10842 | Submission Open
Keywords: colorectal surgery; postoperative pain; surgical site infections; anastomotic leaks; minimally invasive techniques; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
New Therapies and Immunological Findings in Nasopharyngeal Carcinoma
edited by Dora Kwong and Darren Wan Teck Lim
submission deadline 31 Aug 2025 | 4 articles | Viewed by 10402 | Submission Open
Keywords: EBV; tumor microenvironment; neoantigens; checkpoint inhibitors; cellular immunotherapy; vaccine; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Lifestyle Choices and Endocrine Dysfunction on Cancer Onset and Risk submission deadline 31 Aug 2025 | 4 articles | Viewed by 7010 | Submission Open
Keywords: occupational exposure; obesity; nutrition; exercise; endocrine disruptors; reproduction; development; hormone
(This special issue belongs to the Section Tumor Microenvironment)
Updates on Urologic Oncology: From Diagnosis to Localized and Systemic Therapy Options (2nd Edition)
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 5597 | Submission Open
Keywords: bladder cancer; prostate cancer; renal cancer; urologic cancer treatment; urologic cancer diagnosis; urologic cancer innovation; urologic neoplasm therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Pathogenesis and Treatment Strategies in Multiple Myeloma: From Basic Research to Real Life
edited by Shingen Nakamura
submission deadline 31 Aug 2025 | 4 articles | Viewed by 5467 | Submission Open
Keywords: myeloma bone disease; denosumab; bisphosphonate; infectious complication; proteasome inhibitor; IMiDs; anti-CD38 antibody; venetoclax; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
2nd Edition: Molecular Testing for Thyroid Nodules and Cancer submission deadline 31 Aug 2025 | 4 articles | Viewed by 5278 | Submission Open
Keywords: thyroid nodules; thyroid cancer; molecular testing; cytology; fine needle aspiration; personalized medicine; mutations
(This special issue belongs to the Section Methods and Technologies Development)
Robotic Surgery for Gastrointestinal (GI) Malignancies submission deadline 31 Aug 2025 | 5 articles | Viewed by 5021 | Submission Open
Keywords: robotic surgery; colorectal cancer; gastric cancer; liver cancer; pancreatic cancer; esophageal cancer; robotic platform
(This special issue belongs to the Section Clinical Research of Cancer)
Advances in Proton Therapy for Head and Neck Cancer: Techniques, Outcomes and Planning Variations
edited by Jun Zhou
submission deadline 31 Aug 2025 | 2 articles | Viewed by 4544 | Submission Open
Keywords: proton head and neck cancer therapy; protons vs. photons for head and neck cancer treatment; adaptive proton therapy; robustness in proton head and neck cancer therapy; online vs. offline adaptation in proton head and neck cancer therapy
(This special issue belongs to the Section Cancer Therapy)
Diagnosis and Treatment of Gastroenteropancreatic Neuroendocrine Neoplasms (2nd Edition)
edited by Peter Stålberg
submission deadline 31 Aug 2025 | 2 articles | Viewed by 4539 | Submission Open
Keywords: biomarkers; imaging; gastric NETs; pancreatic NETs; small intestinal NETs; receptor-based therapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Emerging Therapies in the Management of Gastrointestinal Malignancies (2nd Edition) submission deadline 31 Aug 2025 | 4 articles | Viewed by 4427 | Submission Open
Keywords: hepatocellular carcinoma; colorectal cancer; esophageal cancer; immunotherapy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Recent Advances on the Role of Intensity–Modulated Radiotherapy in Cancer
edited by Taro Murai
submission deadline 31 Aug 2025 | 2 articles | Viewed by 4415 | Submission Open
Keywords: intensity modulated radiotherapy; medical physics; stereotactic radiotherapy; proton therapy; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Liquid Biopsy in Breast Cancer (2nd Edition) submission deadline 31 Aug 2025 | 2 articles | Viewed by 4368 | Submission Open
Keywords: liquid biopsy; liquid biomarkers; precision oncology; disease monitoring; treatment monitoring; tumor heterogenei-ty; circulating tumor cells (CTCs); circulating tumor DNA (ctDNA); circulating miRNAs; exosomes; extracellular vesicles (EVs)
(This special issue belongs to the Section Cancer Biomarkers)
Paradigm Shifts in Gynaecological Oncology Surgery
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 4036 | Submission Open
Keywords: gynecological surgery; genomics risk management; survivorship health economics
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Combination Therapy in Lymphoma
edited by and Alberto Arribas
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3868 | Submission Open
Keywords: combination therapy; non-Hodgkin lymphoma; Hodgkin lymphoma; targeted agents; antibody drug conjugates; bispecific agents; cellular therapies; immune checkpoint inhibitors and epigenetic agents
(This special issue belongs to the Section Cancer Therapy)
Mathematical Oncology: Using Mathematics to Enable Cancer Discoveries submission deadline 31 Aug 2025 | 1 articles | Viewed by 3713 | Submission Open
Keywords: mathematical oncology; computational biology; mathematical modeling; computational oncology; data-driven modeling; physical oncology
(This special issue belongs to the Section Methods and Technologies Development)
Advances in the Management of Prostate Cancer: New Insights into Biological and Clinical Factors
edited by Mutlay Sayan and
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3573 | Submission Open
Keywords: prostate cancer; risk stratification; genomic alterations; radiation therapy; prostatectomy; androgen deprivation therapy
(This special issue belongs to the Section Cancer Therapy)
Exploring the Interplay of Glioblastoma Angiogenesis, ROS, and Tumor Microenvironment: Advancements in Combination Therapy and Bioinformatics Approaches
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3383 | Submission Open
Keywords: glioblastoma; angiogenesis; reactive oxygen species (ROS); hypoxia-inducible factors (HIFs); radiotherapy (RT); bioactive natural compounds; tumor microenvironment (TME); cancer immunotherapy; combination therapy; autophagy; apoptosis; in silico and network pharmacology; bioinformatics
(This special issue belongs to the Section Cancer Metastasis)
Surgical Treatment of Hepatocellular Carcinoma
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 3380 | Submission Open
Keywords: surgical techniques; surgical indications; surgical outcomes; clinical trials; liver transplantation; adjuvant therapy; basic research
(This special issue belongs to the Section Clinical Research of Cancer)
Research on Fluorescence-Guided Surgery in Cancer Treatment
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2932 | Submission Open
Keywords: fluorescence-guided surgery; fluorescent agents; tumor fluorescence; tumor margin detection; residual tumor assessment; glioma surgery; fluorescein sodium; 5-aminolevulinic acid; confocal endomicroscopy; Raman spectroscopy
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy in Melanoma: Recent Advances and Future Directions (2nd Edition) submission deadline 31 Aug 2025 | 2 articles | Viewed by 2763 | Submission Open
Keywords: melanoma; immunotherapy; prognostic and predictive biomarkers; recurrence-free and overall survival; adjuvant/neoadjuvant immunotherapy; anti-PD1/anti-PD-L1 and anti-CTLA4 agents
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Lectins in Cancer
edited by and Anna S. Świerzko
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2751 | Submission Open
Keywords: lectin; sugar code; epithelial to mesenchymal transition (EMT); metastasis; complement; oncogenic pathogen
(This special issue belongs to the Section Cancer Metastasis)
Advances in Diagnostics and Prognostics in the Management of Intrathoracic Malignancies
edited by Akshay Jatin Patel and Marcus Taylor
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2546 | Submission Open
Keywords: intrathoracic malignancies; diagnostics; prognostics; molecular biomarkers; radiomics; artificial intelligence; immunobiological parameters; personalized therapy
(This special issue belongs to the Section Methods and Technologies Development)
Novel Insights into Cancer-Related Cognitive Impairment
edited by Danielle Tometich
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2545 | Submission Open
Keywords: cognitive impairment; cognitive dysfunction; cancer survivorship; quality of life; neuropsychological assessment; cognitive rehabilitation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Pathology of Lymphoma and Leukemia
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2425 | Submission Open
Keywords: leukemia; lymphoma; immunohistochemical stains; next-generation sequencing; cytogenetics; flow cytometry analysis
(This special issue belongs to the Section Cancer Pathophysiology)
Applications of Ex Vivo Microscopy in Cancer Detection and Diagnosis
edited by J. Quincy Brown
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2293 | Submission Open
Keywords: microscopy; cancer; optical sectioning; diagnosis; detection
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
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