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Cancers
Special Issues
Head and Neck Cancer: Survivorship Challenges and Therapeutic Approaches
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Head and Neck Cancer: Survivorship Challenges and Therapeutic Approaches

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 458

Special Issue Editors

Prof. Dr. Lucía Ortiz-Comino

E-Mail Website
Guest Editor
1. A02-Cuídate, Instituto de Investigación Biosanitaria ibs. GRANADA, 18012 Granada, Spain
2. Sports and Health Research Center (IMUDs), Parque Tecnológico de la Salud, 18007 Granada, Spain
3. BIO277 Group, Department of Physical Therapy, Faculty of Health Sciences, University of Granada, 18071 Granada, Spain
4. Faculty of Health Sciences Faculty (Melilla), University of Granada, 52005 Melilla, Spain
Interests: oncology; head and neck cancer; physical therapy; survivorship; pain
Prof. Dr. Avraham Eisbruch

E-Mail Website
Guest Editor
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Interests: radiology; imaging; head and neck cancer; oropharynx; HPV (Human papillomavirus); Intensity modulated radiotherapy (IMRT); quality of life; xerostomia; dysphagia; Immunotherapy; chemo-radiation
Prof. Dr. Ángela González-Santos

E-Mail Website
Guest Editor
1. 'Cuídate' from Biomedical Group (BIO277), University of Granada, Granada, Spain
2. Department of Physical Therapy, Faculty of Health Sciences, University of Granada, Granada, Spain
3. Instituto de Investigación Biosanitaria ibs, Granada, Spain
Interests: occupational therapy; cognitive impairment; telerehabilitation; breast neoplasms

Special Issue Information

Dear Colleagues,

Addressing challenges during medical treatment and survivorship is of importance to enhance the quality of life of people with head and neck cancer. With this in mind, we aim to meet the need for comprehensive research on all kinds of side effects suffered by head and neck cancer patients and survivors, recognizing that these factors deeply affect individuals and their interaction with society.

This Special Issue will focus on different outcomes regarding head and neck cancer, from different side-effects perceived by patients and survivors and their backgrounds to treatment approaches for these outcomes. All this knowledge will help us achieve our aim to better understand all the challenges that head and neck cancer patients and survivors have to face, and which interventions can improve their general quality of life.

Authors are invited to contribute innovative insights, findings from their empirical research, and systematic reviews to increase the knowledge on head and neck cancer, so that treatment approaches during survivorship can be optimized.

Prof. Dr. Lucía Ortiz-Comino
Prof. Dr. Avraham Eisbruch
Prof. Dr. Ángela González-Santos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck cancer
  • supportive care
  • survivorship care
  • physiotherapy
  • quality of life
  • lifestyle interventions

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

25 pages, 1903 KiB  
Article
Reliability and Clinical Feasibility of Three Assessment Methods for Head and Neck Lymphedema in Head and Neck Cancer Patients
by Kaat Van Aperen, Sandra Nuyts, Thierry Troosters, Nele Devoogdt, Tessa De Vrieze, Ceren Gürsen, Kaat Verbeelen, Johannes Devos and An De Groef
Cancers 2025, 17(10), 1672; https://doi.org/10.3390/cancers17101672 - 15 May 2025
Viewed by 308
Abstract
Background/Objectives: Head and neck lymphedema (HNL) is a common complication after head and neck cancer (HNC) treatment. Reliable and feasible assessment methods are essential for monitoring and management. This study aimed to evaluate the reliability and clinical feasibility of three methods for [...] Read more.
Background/Objectives: Head and neck lymphedema (HNL) is a common complication after head and neck cancer (HNC) treatment. Reliable and feasible assessment methods are essential for monitoring and management. This study aimed to evaluate the reliability and clinical feasibility of three methods for assessing external HNL in HNC patients: local tissue water (%) using the MoistureMeterD Compact (MMDC), neck circumference using a tape measure, and dermal thickness using B-mode ultrasound. Methods: Thirty-three HNC patients with potential HNL were included. Measurements were performed on the same day, twice by the same rater and once by a different rater. Intraclass correlation coefficients (ICC2,1), (relative) standard error of measurement ((%)SEM), smallest real difference (SRD), systematic differences across measurement occasions, and Bland–Altman plots with 95% limits of agreement were analyzed. Time efficiency and clinical limitations were assessed. As an exploratory analysis, Spearman correlations among methods were examined. Results: All methods demonstrated moderate to very strong reliability (ICCs2,1 0.781–0.994), except dermal thickness (ICCs2,1 0.136–0.354). Differences between raters and within one rater were not clinically meaningful. Neck circumference showed the highest reliability (ICCs2,1 0.958–0.994) and was the fastest to perform with the fewest limitations. The methods showed weak correlations with each other. Conclusions: Neck circumference was the most reliable and time-efficient method assessing HNL in clinical practice but is limited to the neck region. For the head, local tissue water assessment seems the most reliable and feasible. The methods assess different aspects of HNL. Further research should confirm how these methods can complement each another. Full article
(This article belongs to the Special Issue Head and Neck Cancer: Survivorship Challenges and Therapeutic Approaches)
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