Clinical Application of Proton Therapy and Advanced Radiotherapy in Gynecological Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 63
Special Issue Editors
Interests: proton therapy; gynecological cancer; MR-guided radiotherapy; brachytherapy
Special Issue Information
Dear Colleagues,
Radiotherapy is pivotal in the definitive treatment of gynecological cancers: as curative intent in locally advanced cervical cancer with brachytherapy and vaginal cancers; as post-operative therapy in endometrial, cervical and vulval cancers, and for isolated recurrences such as para-aortic or other regional nodal or bone recurrence. Intensity-modulated radiotherapy emerges as the new gold standard compared to the conventional four-field “box” technique, with merits in reducing acute and late gastrointestinal and urinary toxicities. A more sophisticated technique using image-guidance, such as tomotherapy using MVCT or MR-guided radiotherapy with the latest MR-Linac technology, allows margin reduction and potential further sparing of toxicities. Proton or heavy-particle therapy is now being investigated as a superior modality, with studies demonstrating dosimetric improvement, especially in a post-operative setting and extended field para-aortic irradiation.
This Special Issue aims to illustrate current clinical experience in the latest image-guided radiotherapy or proton therapy applications across gynecological cancer applications.
Dr. Amy Tien Yee Chang
Dr. Bin Yang
Guest Editors
Manuscript Submission Information
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Keywords
- proton therapy
- cervical cancer
- endometrial cancer
- vaginal cancer
- MR-guided radiotherapy
- MR-guided brachytherapy
- stereotactic body radiotherapy
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