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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 30 Jun 2026 | 6 articles | Viewed by 6195 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Sequence Variants in Breast/Ovarian Cancer Susceptibility Genes: From Risk Assessment to Clinical Management in Carrier Individuals and Their Blood Relatives

edited by Arcangela De Nicolo and

Miguel De la Hoya

submission deadline 30 Jun 2026 | 3 articles | Viewed by 6034 | Submission Open

Keywords: breast/ovarian cancer susceptibility genes; risk assessment and clinical management of carrier individuals and their blood relatives; risk models; variant classification; multifactorial approaches

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Palliative Radiotherapy for Cancer

edited by Rebecca Wong

submission deadline 30 Jun 2026 | 3 articles | Viewed by 5905 | Submission Open

Keywords: symptom relief; symptom control; radiation medicine; radiotheranostics; theranostics; external beam radiotherapy; palliation; oligometastases; oligoprogression; systematic reviews and meta-analyses; patient reported outcomes; abscopal effect; combined modality; education; clinical practice

(This special issue belongs to the Section Cancer Therapy)

Fertility Preservation in Gynecological Cancer

edited by

Giuseppe Gullo

and

Luigi Della Corte

submission deadline 30 Jun 2026 | 3 articles | Viewed by 5751 | Submission Open

Keywords: gynecological cancer; fertility preservation; surgery treatments; fertility sparing; psychological implication

(This special issue belongs to the Section Methods and Technologies Development)

Chemoprevention Advances in Cancer (2nd Edition)

edited by

Komal Raina

submission deadline 30 Jun 2026 | 3 articles | Viewed by 5626 | Submission Open

Keywords: cancer prevention; chemoprevention; nutrition and cancer; bio-active food components; natural products; non-toxic anticancer agents; precision nutrition in cancer; tumor metabolomics; gut microbiome in cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

NK Cells in the Tumor Microenvironment: Immunosuppressive Mechanisms and Therapy

edited by

Alexander Barrow

and Julian Vivian

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5617 | Submission Open

Keywords: immunosuppression; activation; inhibition; receptor; NK-CAR; checkpoint; adoptive cell therapy; immunotherapy; tumor microenvironment; nanoparticles

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in PET/CT for Predicting Cancer Outcomes

edited by Ahmad Shariftabrizi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 5558 | Submission Open

Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism

(This special issue belongs to the Section Methods and Technologies Development)

Recent Advances in Peritoneal Carcinomatosis

edited by Neda Dadgar and Patrick L. Wagner

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5406 | Submission Open

Keywords: peritoneal carcinomatosis; tumor microenvironment; immunotherapy biomarkers; microbiome– host interactions; epithelial– mesenchymal transition (emt); intra-cavitary therapies; cytokine signaling; translational oncology; multiomics profiling; organoid

(This special issue belongs to the Section Clinical Research of Cancer)

Neuroscience of Brain Tumors

edited by Zefferino Rossini,

Miguel Segura Ginard

and Maria Pia Tropeano

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5207 | Submission Open

Keywords: neurosurgery; neuroscience; brain tumors (gliomas; meningiomas; and pituitary tumors); neural pathway; neuroimaging; neurogenetics

Advances in Blood Cancers: How We Define Success

edited by

Stefano Molica

and

David Allsup

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5076 | Submission Open

Keywords: blood cancers; research-driven advancements; cure rates; novel agents

(This special issue belongs to the Section Cancer Therapy)

Urological Cancer: Epidemiology and Genetics

edited by Ilir Agalliu and Evan Kovac

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4934 | Submission Open

Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Molecular Pathology and Human Cancers

edited by

Stefano Marletta

, Alessandro Russo and Giuliana Pavone

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4926 | Submission Open

Keywords: molecular pathology; cancer pathogenesis; targeted therapy; personalized medicine; cancer signaling

(This special issue belongs to the Section Cancer Pathophysiology)

Neurosurgical Advances in Brain Tumor Surgery

edited by Camilla Bonaudo, Alessandro Della Puppa and

Antonello Grippo

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4826 | Submission Open

Keywords: brain lesions/tumors; preoperative mapping; neuro-oncology; navigated TMS (n TMS); brain stimulation; optical imaging; cognitive mapping; awake surgery; functional mapping; functional preservation; intraoperative monitoring; neurophysiological monitoring

(This special issue belongs to the Section Clinical Research of Cancer)

Modern Neurosurgical Management of Gliomas

edited by

Arthur Wagner

and

Chiara Negwer

submission deadline 30 Jun 2026 | 4 articles | Viewed by 4791 | Submission Open

Keywords: precision medicine; personalized oncological surgery; intraoperative imaging; fluorescence-guided surgery; intraoperative histopathology; liquid biopsy; minimally invasive oncological surgery; radiosurgery

(This special issue belongs to the Section Cancer Therapy)

Molecular and Genetic Biomarkers in Oral Squamous Cell Carcinoma

edited by

Kalu U.E. Ogbureke

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4760 | Submission Open

Keywords: oral cancer; oropharyngeal cancer; biomarkers; liquid biopsy; genetic determinants

(This special issue belongs to the Section Cancer Biomarkers)

Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice

edited by

Maria Trovato

, Silvia Martina Ferrari and

Fausto Famà

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4671 | Submission Open

Keywords: thyroid cancer; precision diagnosis; clinical management; molecular tests; molecular therapeutic targets; thyroid cancer epidemiology; artificial intelligence; health inequalities

(This special issue belongs to the Section Clinical Research of Cancer)

Surgery in Metastatic Cancer (2nd Edition)

edited by

Ulrich Ronellenfitsch

submission deadline 30 Jun 2026 | 4 articles | Viewed by 4664 | Submission Open

Keywords: metastatic cancer; surgery; metastasectomy; indication; timing

(This special issue belongs to the Section Cancer Therapy)

Clinical Pathology of Lung Cancer (2nd Edition)

edited by

Letizia Gnetti

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4326 | Submission Open

Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Cutaneous Metastases: State-of-the-Art Research and Management

edited by Marios N. Papadakis and

Dimitra Koumaki

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4130 | Submission Open

Keywords: cutaneous metastases; cancer skin metastasis; metastatic skin lesions; diagnosis of cutaneous metastases; oncology; skin oncology; patient outcomes

(This special issue belongs to the Section Cancer Metastasis)

Advances in Breast Cancer Imaging: From Detection to Personalized Diagnosis

edited by

Nuno Matela

and

Ana Margarida Mota

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4098 | Submission Open

Keywords: breast cancer imaging; artificial intelligence; radiomics; deep learning; personalized diagnosis; multimodal imaging; predictive modeling; early detection; treatment response; clinical applications

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Technical and Technological Innovations in Head and Neck Cancer Surgery

edited by Marta Filauro

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4079 | Submission Open

Keywords: head and neck; squamous cell carcinoma; larynx; oral cavity; free flap; exoscope; TORS

(This special issue belongs to the Section Methods and Technologies Development)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3884 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Radioimmunotherapy, Neoadjuvant Immunotherapy, and Adjuvant Immunotherapy for Cancer

edited by

Rashidul Alam Mahumud

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3734 | Submission Open

Keywords: immunotherapy; radioimmunotherapy; neoadjuvant immunothearpy; radiopharmaceuticals

(This special issue belongs to the Section Cancer Therapy)

Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention

edited by Adam Barsouk

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3143 | Submission Open

Keywords: epidemiology; disparities; oncology; cancer; prevention

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Immunotherapy Approaches in Breast Cancer Treatment (2nd Edition)

edited by Yi Huang and

Bing Li

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3050 | Submission Open

Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Contemporary Management for Gallbladder Cancer: From Diagnosis to Treatment (2nd Edition)

edited by Hiromichi Ito

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3016 | Submission Open

Keywords: gallbladder cancer; radical cholecystectomy; adjuvant chemotherapy; neoadjuvant therapy; incidental gallbladder cancer; multidisciplinary management; preoperative staging

(This special issue belongs to the Section Cancer Therapy)

Deep Learning and Radiomics for Cancer Diagnosis, Staging, and Treatment Response

edited by Mohamed Shehata,

Mostafa Elhosseini

Mahmoud Badawy

and Hanaa ZainEldin

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2932 | Submission Open

Keywords: radiomics; deep learning; cancer imaging; diagnosis; staging; treatment response; machine learning; medical image analysis; precision oncology; federated learning; AI in healthcare

(This special issue belongs to the Section Methods and Technologies Development)

Understanding the Molecular Basis and Immunobiology of Renal Cell Carcinoma and Exploring Novel Therapeutic Strategies

edited by

Heba Khella

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2919 | Submission Open

Keywords: renal cell carcinoma; molecular basis; immunobiology; tumor microenvironment; immunotherapy; targeted therapy; metastasis; precision medicine; biomarkers; non-coding RNA; miRNA; prognosis; molecular diagnostics; translational research

(This special issue belongs to the Section Cancer Therapy)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2918 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2825 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Accelerated Partial Breast Irradiation

edited by Roxolyana Abdah-Bortnyak

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2731 | Submission Open

Keywords: radiotherapy; accelerated partial breast irradiation; breast cancer; intraoperative radiotherapy; external beam radiotherapy; brachytherapy

(This special issue belongs to the Section Cancer Therapy)

Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management

edited by

Stefano Cacciatore

and Luiz Zerbini

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2719 | Submission Open

Keywords: hepatocellular carcinoma (HCC); cholangiocarcinoma; pancreatic ductal adenocarcinoma (PDAC); tumour microenvironment; molecular biomarkers; therapeutic resistance; cancer immunotherapy; early cancer detection; precision oncology; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Neoadjuvant Therapy for Urologic Cancer

edited by Carlo Messina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2674 | Submission Open

Keywords: neoadjuvant treatment; bladder cancer; prostate cancer; renal cell carcinoma; penile cancers; immunotherapy; antibody– drug conjugates

(This special issue belongs to the Section Cancer Therapy)

The Use of Artificial Intelligence in Predicting Response to Cancer Therapy

edited by

Arturo Loaiza-Bonilla

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2656 | Submission Open

Keywords: artificial intelligence; response prediction; precision oncology; machine learning; multimodal data integration; immunotherapy biomarkers; treatment resistance; clinical decision support; real-world data; explainable AI

Head and Neck Cancer: Survivorship Challenges and Therapeutic Approaches

edited by

Lucía Ortiz-Comino

, Avraham Eisbruch and

Ángela González-Santos

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2652 | Submission Open

Keywords: head and neck cancer; supportive care; survivorship care; physiotherapy; quality of life; lifestyle interventions

(This special issue belongs to the Section Cancer Therapy)

Ultrasound for Cancer Therapy

edited by Zhen Xu and

Natasha D. Sheybani

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2635 | Submission Open

Keywords: HIFU; histotripsy; drug delivery; immunotherapy; sonodynamic therapy; blood brain barrier opening; sonobiopsy; cancer treatment; image-guided therapy

(This special issue belongs to the Section Cancer Therapy)

Diagnosis of Hematologic Malignancies: 2nd Edition

edited by

Leonor Arenillas

and

Xavier Calvo

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2551 | Submission Open

Keywords: diagnosis of hematologic malignancies; myeloid neoplasms; lymphoid neoplasms; cytomorphology; flow cytometry; cytogenetic; molecular biology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Quantitative Imaging, AI, and Novel Imaging Techniques for Precision Radiology in Prostate Cancer

edited by Rulon R. Mayer,

Charles Simone

and

Yuan Yuan

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2437 | Submission Open

Keywords: prostate cancer; multi-parametric MRI (mpMRI); bi-parametric MRI; positron emission tomography (PET); computed tomography (CT); ultrasound (US); artificial intelligence (AI); convolutional neural network; visual language model; computer-aided diagnosis; spatially registered multi-parametric MRI; prostate specific membrane antigen in PET/CT

(This special issue belongs to the Section Methods and Technologies Development)

New Insights in the Management of Resectable Esophageal Malignancy

edited by

Tania Triantafyllou

and Dimitrios A. Theodorou

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2369 | Submission Open

Keywords: esophageal cancer; perioperative chemotherapy; radiotherapy; immunotherapy; radical surgical resection

(This special issue belongs to the Section Methods and Technologies Development)

The Role of Anatomical Resections in Secondary Lung Cancer: Indications, Techniques, and Outcomes

edited by

Andrea Dell'Amore

and

Alessio Campisi

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2243 | Submission Open

Keywords: anatomical resections; segmentectomy; lobectomy; secondary lung cancer; pulmonary metastases; thoracic surgery; minimally invasive surgery; surgical outcomes; lung neoplasms; personalized treatment

(This special issue belongs to the Section Clinical Research of Cancer)

Dendritic Cells and Immune Checkpoints Within the Tumor Microenvironment: Mechanisms, Models, and Therapy

edited by

Francisco J. Cueto

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2200 | Submission Open

Keywords: tumor immune microenvironment; immune checkpoint blockade; dendritic cells; antigen presentation; T-cell responses

(This special issue belongs to the Section Tumor Microenvironment)

Non-Coding RNAs and Extracellular Vesicles in Cancer Crosstalk: Diagnostic and Therapeutic Implications 2nd Edition

edited by

Simona Taverna

and

Giuseppe Cammarata

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2003 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; inflammation; non-coding RNA; microRNAs; circular-RNAs; PIWI-RNAs; lnc-RNAs

(This special issue belongs to the Section Cancer Therapy)

Updates on Anti-Cancer Drug Research

edited by

Ana Luísa De Sousa-Coelho

and Mónica Fernandes

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1994 | Submission Open

Keywords: anti-cancer drug research; drug resistance; biomarkers; pharmacogenomics; single-cell RNA sequencing; non-coding RNAs; multi-omics data

(This special issue belongs to the Section Cancer Drug Development)

Targeted Radiotracers for Molecular Imaging and Therapy in Cancer

edited by

Vladimir Tolmachev

and

Maryam Oroujeni

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1932 | Submission Open

Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Autophagy and Apoptosis in Cancer Progression

edited by Antonio Ieni

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1902 | Submission Open

Keywords: autophagy; apoptosis; cancer progression; cell death pathways; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Proton and Light Ion Therapy for Cancer

edited by Oliver Jäkel

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1886 | Submission Open

Keywords: novel beam delivery concepts; image guidance; adaptive therapy; in vivo monitoring; radiobiological studies with protons and light ions; clinical studies; outcome reports

(This special issue belongs to the Section Cancer Therapy)

Cancer Inhibitory Receptors: Targeting Tumor Microenvironment Therapeutically

edited by

Vaishali Aggarwal

and Alok Kumar

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1873 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy; tumor microenvironment; inhibitory receptors; immune system; T cells; malignant cells; therapeutic targets

(This special issue belongs to the Section Cancer Therapy)

Neurofibromatosis Type 1 (NF1) Related Tumors (2nd Edition)

edited by

Daochun Sun

and

Sameer Farouk Sait

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1862 | Submission Open

Keywords: NF1; tumorigenesis; cancer stem cells; targeted therapy; tumor microenvironment; epigenetics; case report; metastasis; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Advanced Segmentation in Multimodal Nuclear Imaging of Solid Tumors and Lymphomas: Tools, Challenges, and Clinical Integration

edited by

Ken Kudura

and Robert Förster

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1850 | Submission Open

Keywords: multimodal nuclear imaging; artificial intelligence in nuclear medicine; radiomics in nuclear medicine; tumor segmentation; segmentation techniques; segmentation tools; outcome prediction; radioligand therapy

(This special issue belongs to the Section Methods and Technologies Development)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1838 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Displaying special issue 151-200 on page 4 of 26.