Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Applications of Ultrasound in Cancer Imaging and Treatment
edited by Gregory Jan Czarnota
submission deadline 25 Oct 2024 | Viewed by 252 | Submission Open
Keywords: ultrasound; imaging; CT; MRI; treatment
(This special issue belongs to the Section Methods and Technologies Development)
New and Emerging Strategies for Targeting Genomic Instability and Overcoming Drug Resistance in Lung Cancer
edited by Kelsie L. Thu
submission deadline 25 Oct 2024 | Viewed by 236 | Submission Open
Keywords: lung cancer; genomic instability; drug resistance; treatment strategy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Relationship between Protein and Metabolite in Cancers
edited by
submission deadline 25 Oct 2024 | Viewed by 140 | Submission Open
Keywords: cancer progression; cancer cells; proteins; metabolites; signaling pathway; metabolic dysregulations
(This special issue belongs to the Section Tumor Microenvironment)
Recent Advances in the Understanding of Myelodysplastic Syndrome and Acute Myeloid Leukemia
edited by , Konstantinos Liapis and
submission deadline 28 Oct 2024 | 9 articles | Viewed by 24494 | Submission Open
Keywords: myelodysplastic syndrome; acute myeloid leukemia; bone marrow microenvironment; targeted therapies; hematopoietic stem cell; leukemic stem cell; hematopoietic stem cell transplantation
(This special issue belongs to the Section Cancer Therapy)
Diagnostics and Therapeutics Advances in Pancreatic Cancer submission deadline 30 Oct 2024 | 7 articles | Viewed by 13035 | Submission Open
Keywords: pancreatic cancer; pancreatic adenocarcinoma; IPMN; neoadjuvant chemotherapy; minimally invasive pancreatic resection; robotic pancreatic resection; radiomics; DWI; pancreatic electroporation
(This special issue belongs to the Section Molecular Cancer Biology)
Immunotherapy for Hepatocellular Carcinoma: Novel Experimental Approaches and Biomarkers submission deadline 30 Oct 2024 | 3 articles | Viewed by 4846 | Submission Open
Keywords: immunotherapy; hepatocellular carcinoma; liver diseases; liver immunology; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Developments in Artificial Intelligence and Advanced Medical Imaging in Cancers
edited by
submission deadline 30 Oct 2024 | 3 articles | Viewed by 2973 | Submission Open
Keywords: oncologic imaging; artificial intelligence; machine learning; deep learning; radiomics; photon-counting computed tomography; spectral computed tomography; ultra-high-field magnetic resonance imaging; ultra-high-frequency ultrasound
(This special issue belongs to the Section Methods and Technologies Development)
Lymph Node Dissection for Gynecologic Cancers
edited by
submission deadline 30 Oct 2024 | 2 articles | Viewed by 2822 | Submission Open
(This special issue belongs to the Section Methods and Technologies Development)
CAR T Therapy of Solid Cancers: Problems and Progress
edited by John F. Marshall and Lauren Cutmore
submission deadline 30 Oct 2024 | 2 articles | Viewed by 1832 | Submission Open
Keywords: CAR T therapy; tumor microenvironment; solid tumor; treatment; immuno-competent models
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
What Is New in the Treatment of Intraocular (Uveal) Melanoma submission deadline 30 Oct 2024 | 1 articles | Viewed by 1786 | Submission Open
Keywords: uveal melanoma; plaque brachytherapy; ocular tumors; proton therapy; transpupillary thermotherapy; molecular prognostication; gene expression
(This special issue belongs to the Section Cancer Therapy)
Gastric Cancer Surgery: Gastrectomy, Risk, and Related Prognosis submission deadline 30 Oct 2024 | 1 articles | Viewed by 1540 | Submission Open
Keywords: gastric cancer; surgical treatment; gastrectomy; outcome; minimally invasive surgical
(This special issue belongs to the Section Clinical Research of Cancer)
Role of Cytokines in Cancer submission deadline 30 Oct 2024 | 2 articles | Viewed by 1516 | Submission Open
Keywords: inflammation; tumor microenvironment; cytokines
(This special issue belongs to the Section Tumor Microenvironment)
The Progress of Pancreatectomy for Pancreatic Cancer Treatment submission deadline 30 Oct 2024 | 1 articles | Viewed by 976 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatectomy timing in multimodal regimen; minimally invasive pancreatectomy for PDAC; pancreatectomy and resectability; extended pancreatectomy; vascular resection and reconstruction; outcome research— pancreatectomy for cancer in unselected patient cohorts; interaction of postoperative complications and preoperative or adjuvant therapy; postoperative pancreatic fistula
(This special issue belongs to the Section Clinical Research of Cancer)
The Application of Laparo-Endoscopic and Robotic Surgery in Cancer Treatments and Research
edited by Yutaro Kato
submission deadline 30 Oct 2024 | 1 articles | Viewed by 918 | Submission Open
Keywords: cancer; minimally invasive surgery; laparoscopic surgery; endoscopic surgery; robotic surgery; telesurgery; periop-erative outcomes; oncologic outcomes; clinicopathology; molecular biology
(This special issue belongs to the Section Cancer Therapy)
Pathology of Pediatric Cancers submission deadline 30 Oct 2024 | Viewed by 364 | Submission Open
Keywords: pediatric cancers; pathology; oncogenesis; childhood tumors; molecular profiling; histopathology; diagnostic challenges; targeted therapy; immunological aspects; prognostic markers
(This special issue belongs to the Section Pediatric Oncology)
From Genomics and Immunogenomics to Treatments of Head and Neck Cancer
edited by Vivian Wai Yan Lui and Yan Cui
submission deadline 30 Oct 2024 | Viewed by 263 | Submission Open
Keywords: head and neck cancer; genomics; immunogenomics; multi-omics; immunotherapy; translational research; preclinical drug development; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Genitourinary Cancer: The Latest Advances in Diagnosis and Therapy
edited by Sanja Štifter-Vretenar
submission deadline 30 Oct 2024 | Viewed by 159 | Submission Open
Keywords: genitourinary cancer; prevention; epidemiology; diagnosis; diagnostic markers; oncogenesis; tumor biology; pathology; prognostic indicators; targeted therapy; multimodality therapy; integrative therapy
(This special issue belongs to the Section Clinical Research of Cancer)
Innovation in Reconstruction after Sarcoma Resection in Musculoskeletal System
edited by
submission deadline 30 Oct 2024 | Viewed by 132 | Submission Open
Keywords: limb salvage in sarcoma; free fibula after sarcoma resection; 3D-printed prosthesis; cryotherapy; chest sarcoma; soft tissue reconstruction in sarcoma; lymphedema in sarcoma; LVA
(This special issue belongs to the Section Clinical Research of Cancer)
Artificial Intelligence in Cancer Screening submission deadline 31 Oct 2024 | 9 articles | Viewed by 29230 | Submission Open
Keywords: artificial intelligence; biomarkers; breast cancer; cancer screening; cervical cancer; colorectal cancer; deep learning; lung cancer; machine learning; risk stratification
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Hypofractionated Radiotherapy in Cancer Treatments submission deadline 31 Oct 2024 | 7 articles | Viewed by 15298 | Submission Open
Keywords: hypofractionation; SBRT; brachytherapy; therapeutic ratio; hypofractionated radiotherapy
(This special issue belongs to the Section Cancer Therapy)
Microtubule-Associated Proteins (MAPs) and Cancers
edited by and Christian Poüs
submission deadline 31 Oct 2024 | 3 articles | Viewed by 11400 | Submission Open
Keywords: Microtubule; tubulin; tau; stathmin; EB1; dynein; kinesin; biomarker; target
(This special issue belongs to the Section Molecular Cancer Biology)
Head and Neck Cancers—Novel Approaches and Future Outlook
edited by
submission deadline 31 Oct 2024 | 7 articles | Viewed by 11246 | Submission Open
Keywords: tumor microenvironment; biomarker; patient-derived tumor models; novel treatment approaches; combination strategies; prognostic marker; liquid biopsy; neoadjuvant treatment
(This special issue belongs to the Section Cancer Biomarkers)
The Analysis of Circulating Tumor Cells (CTCs): New Insights into the Biology of Cancers submission deadline 31 Oct 2024 | 5 articles | Viewed by 10553 | Submission Open
Keywords: CTC; DTC; ctDNA; minimal residual disease; MRD; liquid biopsy; circulating biomarkers; single cell analysis
(This special issue belongs to the Section Molecular Cancer Biology)
Radiation Therapy for Pancreatic Cancer submission deadline 31 Oct 2024 | 6 articles | Viewed by 9780 | Submission Open
Keywords: radiation therapy; pancreatic cancer; image-guided adaptive radiation therapy; artificial-intelligence-based systems; RT effectiveness
(This special issue belongs to the Section Cancer Therapy)
Oncolytic Viruses: A Key Step toward Cancer Immunotherapy
edited by Louisa Chard Dunmall
submission deadline 31 Oct 2024 | 5 articles | Viewed by 9453 | Submission Open
Keywords: oncolytic viruses; tumor microenvironment; immunotherapy; checkpoint inhibitors; BiTE; stroma; CAR-T
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Oncology: State-of-the-Art Research and Initiatives in Japan submission deadline 31 Oct 2024 | 5 articles | Viewed by 9098 | Submission Open
Keywords: Japan; cancer; oncology; research; clinical trial; survivorship; patient support
State of the Art and New Approaches to Spinal Cord Tumors
edited by Cédric Y. Barrey and Gabriele Capo
submission deadline 31 Oct 2024 | 7 articles | Viewed by 8006 | Submission Open
Keywords: neurosurgery; spinal cord tumors; ependymoma; microsurgery; neuromonitoring; neuroradiology; neurorehabilitation; neurohistology; neuro-oncology; intramedullary tumors
(This special issue belongs to the Section Methods and Technologies Development)
Radiation Therapy for Brain Tumors
edited by
submission deadline 31 Oct 2024 | 3 articles | Viewed by 5930 | Submission Open
Keywords: radiosurgery; hypofractionated radiosurgery; spectroscopic MRI; proton radiation; image-guided radiotherapy; radiotherapy for benign tumors; radiotherapy for gliomas; gamma knife
(This special issue belongs to the Section Cancer Therapy)
Applications of Machine and Deep Learning in Thoracic Malignancies
edited by , Yeun-Chung Chang and
submission deadline 31 Oct 2024 | 4 articles | Viewed by 5185 | Submission Open
Keywords: deep learning; esophageal cancer; genomics; lung cancer; machine learning; radiomics; thoracic malignancies; pathology; proteomics; thymoma
(This special issue belongs to the Section Methods and Technologies Development)
Regulation of HIFs in Cancer Cells submission deadline 31 Oct 2024 | 3 articles | Viewed by 4904 | Submission Open
Keywords: Hypoxia; Hypoxia-inducible Factors (HIFs); tumor microenvironment; cancer; oxygen; transcription; post-translational modifications; mRNA synthesis
(This special issue belongs to the Section Tumor Microenvironment)
Targeted Treatment of Brain Cancer: From Basic Research to Clinical Relevance in the Treatment of Glioma Patients
edited by and Dorte Schou Nørøxe
submission deadline 31 Oct 2024 | 3 articles | Viewed by 4815 | Submission Open
Keywords: targeted treatment; personalized medicine; glioma; glioblastoma; tumor heterogeneity; tumor microenvironment
(This special issue belongs to the Section Clinical Research of Cancer)
Cancer-Therapy-Related Adverse Events in Organs
edited by and Pauline Funchain
submission deadline 31 Oct 2024 | 4 articles | Viewed by 4788 | Submission Open
Keywords: cancer; cancer therapy; toxicities; adverse events
(This special issue belongs to the Section Cancer Therapy)
Updates on Depression among Cancer Patients
edited by Wen-Yu Hu, and
submission deadline 31 Oct 2024 | 3 articles | Viewed by 3894 | Submission Open
Keywords: depression; cancer patients; mental health; psycho-oncology; treatment; psychosocial interventions; survivorship; comorbidity; quality of life; neurobiology
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Updates on the Molecular Profile of Gastrointestinal Stromal Tumors (Volume II) submission deadline 31 Oct 2024 | 3 articles | Viewed by 3703 | Submission Open
Keywords: molecular profile; novel tumor biomarkers; predictive biomarkers for therapeutic outcomes; immunological profile; GIST immune microenvironment; immunotherapy
(This special issue belongs to the Section Molecular Cancer Biology)
Recent Advances in Hepatobiliary Cancers: From Diagnosis to Treatment (2nd Edition)
edited by
submission deadline 31 Oct 2024 | 2 articles | Viewed by 3409 | Submission Open
Keywords: hepatobiliary cancers; hepatocellular carcinoma; cholangiocarcinoma; gallbladder cancer; immunotherapy; targeted therapy; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Evidence from the Real World Provides New Insights into the Evolving Landscape of Cancer Immunotherapy
edited by Fabrizio Nelli, and Enzo Ruggeri
submission deadline 31 Oct 2024 | 3 articles | Viewed by 3349 | Submission Open
Keywords: immune-checkpoint inhibitors; solid tumors; cytotoxic chemotherapy; targeted therapies; radiotherapy; concomitants medications; supportive therapies; real-world investigation
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Radiation Dose in Cancer Radiotherapy
edited by
submission deadline 31 Oct 2024 | 1 articles | Viewed by 2754 | Submission Open
Keywords: radiation dosimetry; radiation detectors; radiotherapy treatment planning; radiotherapy technological developments; cancer patients
(This special issue belongs to the Section Cancer Therapy)
Health Services Research in Cancer Care
edited by Francesco Giusti and
submission deadline 31 Oct 2024 | 2 articles | Viewed by 2623 | Submission Open
Keywords: cancer care; cancer care outcomes; cancer care services; cancer costs; treatment; health systems; quality; survival; indicators; health technology assessments
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Recent Updates on Cancer Stem Cells and Tumor Microenvironment
edited by Jer-Yen Yang and
submission deadline 31 Oct 2024 | 1 articles | Viewed by 2573 | Submission Open
Keywords: cancer stem cells; tumor microenvironment; tumor heterogeneity; plasticity; metastasis; therapeutic resistance
(This special issue belongs to the Section Tumor Microenvironment)
Novel Targeted Therapies in Brain Tumors submission deadline 31 Oct 2024 | 1 articles | Viewed by 2379 | Submission Open
Keywords: precision-medicine; targeted-therapy; brain tumors; immunotherapy; glioma; meningioma
(This special issue belongs to the Section Cancer Therapy)
Hematopoietic Stem Cell Transplant in Hematological Malignancies
edited by and Alessandro Cignetti
submission deadline 31 Oct 2024 | 2 articles | Viewed by 2062 | Submission Open
Keywords: stem cell transplant; graft-versus-host disease; conditioning regimen; prophylaxes; immunology; donors; hematological disease
(This special issue belongs to the Section Cancer Therapy)
Recent Advances in Pancreatic Surgery for Pancreatic Ductal Adenocarcinoma
edited by Shuji Isaji
submission deadline 31 Oct 2024 | 1 articles | Viewed by 2051 | Submission Open
Keywords: neoadjuvant therapy; adjuvant therapy; resectability; conversion surgery; surgical technique; laparoscopic surgery; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
Curative Therapies for Non-small Cell Lung Cancer
edited by John Michael Varlotto
submission deadline 31 Oct 2024 | 1 articles | Viewed by 1661 | Submission Open
Keywords: radiotherapy; surgery; early-stage NSCLC; oligometastases; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Radioligand Therapy (RLT) in Neuroendocrine Neoplasms
edited by
submission deadline 31 Oct 2024 | 2 articles | Viewed by 1478 | Submission Open
Keywords: neuroendocrine neoplasms (NENs); neuroendocrine tumors (NETs); radioligand therapy (RLT); peptide receptor radionuclide therapy (PRRT)
(This special issue belongs to the Section Cancer Therapy)
Prostate Cancer Therapy: Supporting Strategies and Management Options
edited by and
submission deadline 31 Oct 2024 | 1 articles | Viewed by 958 | Submission Open
Keywords: prostate cancer; therapy; supporting strategies; management options; lifestyle modifications; dietary interventions; risk reduction techniques; prehabilitation; physical activity; interdisciplinary approach; cancer early detection strategies; rehabilitation; complications
(This special issue belongs to the Section Cancer Therapy)
MicroRNA and Cancer Immunology
edited by
submission deadline 31 Oct 2024 | Viewed by 530 | Submission Open
Keywords: microRNA; miRNA; tumor microenvironment; biomarkers; cancer immunology; cancer treatment; therapeutic target; tumor angiogenesis; tumor metastasis
(This special issue belongs to the Section Tumor Microenvironment)
Microbiomes and Modulation of Therapeutic Responses in Cancer
edited by and Angelos D. Gritzapis
submission deadline 31 Oct 2024 | Viewed by 472 | Submission Open
Keywords: immunomodulation; microbiome; tumor microenvironment; cancer immunotherapy; microbial components; genomic profiling
(This special issue belongs to the Section Tumor Microenvironment)
Pathology of Hematologic Malignancies
edited by
submission deadline 31 Oct 2024 | Viewed by 350 | Submission Open
Keywords: hematologic malignancy; acute leukemia; lymphoma; lymphoproliferative disorder; myeloid neoplasm; genetic abnormalities; pediatric and/or germline mutation-associated disorders
(This special issue belongs to the Section Cancer Pathophysiology)
Applications of Ex Vivo Microscopy in Cancer Detection and Diagnosis
edited by J. Quincy Brown
submission deadline 31 Oct 2024 | Viewed by 315 | Submission Open
Keywords: microscopy; cancer; optical sectioning; diagnosis; detection
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Radiation Therapy for Head and Neck Cancer submission deadline 31 Oct 2024 | Viewed by 249 | Submission Open
Keywords: adaptive radiotherapy  ; hyper- and hypo-fractionated radiotherapy  ; artificial intelligence in radiotherapy for head and neck cancer  ; quality assurance and set-up errors associated with IMRT; VMAT; IGRT; and SGRT techniques  ; protons and heavy ions for radiotherapy  ; re-irradiation  ; nanoparticles plus radiotherapy  ; hyperthermia plus radiotherapy  ; radiotherapy plus immunotherapy  ; the de-escalation of radiation therapy
(This special issue belongs to the Section Cancer Therapy)
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