Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements and Treatment Strategies for Central Nervous System Malignancies and Cancer Stem Cells
edited by Mingli Liu
submission deadline 30 Jun 2025 | Viewed by 231 | Submission Open
Keywords: central nervous system; signaling pathways; cancer stem cells; biomarker; tumor microenvironment
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in PET/CT Application in Urological Cancer
edited by
submission deadline 30 Jun 2025 | Viewed by 231 | Submission Open
Keywords: prostate cancer; urothelial cancer; kidney cancer; diagnosis; staging; treatment; PSMA PET CT; FDG PET CT; CAIX imaging
(This special issue belongs to the Section Cancer Therapy)
Diagnosis, Staging, and Management for Gynecologic Oncology
edited by
submission deadline 30 Jun 2025 | Viewed by 219 | Submission Open
Keywords: gynecologic oncology; cancer biology; HPV infection; molecular risk factors; translational medicine; cancer staging systems; radiation therapy; brachytherapy; radioresistance
(This special issue belongs to the Section Cancer Therapy)
The Role of Circulating Tumor Cells in Cancer Metastasis
edited by Ammar A. Javed
submission deadline 30 Jun 2025 | Viewed by 216 | Submission Open
Keywords: circulating tumor cells (CTCs); cancer metastasis; cancer detection
(This special issue belongs to the Section Cancer Metastasis)
Lymph Node Detection in Gynecological Cancers
edited by Roberto Berretta
submission deadline 30 Jun 2025 | Viewed by 212 | Submission Open
Keywords: sentinel node; endometrial cancer; cervical cancer; vulvar cancer; nodal staging; ultra-staging; isolated tumor cells; micrometastasis; nodal staging
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advanced Prostate Cancer: From Bench to Bedside: 2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 205 | Submission Open
Keywords: prostate cancer; castration resistance; metastases; abiraterone; enzalutamide; apalutamide; docetaxel; darolutamide; PARP inhibitors
(This special issue belongs to the Section Cancer Therapy)
Innovative Treatments Based on Genomic Aberrations in Leukemia and Lymphoma submission deadline 30 Jun 2025 | Viewed by 201 | Submission Open
Keywords: leukemia; lymphoma; AI and predictive modeling; MRD; B-ALL; DLBCL; genomics; treatment  
(This special issue belongs to the Section Cancer Therapy)
Hematopoietic Stem-Cell Transplantation for Acute Myeloid Leukemia
edited by Nidhi Jyotsana
submission deadline 30 Jun 2025 | Viewed by 184 | Submission Open
Keywords: hematopoietic stem cell transplantation (HSCT); acute myeloid leukemia (AML); leukemic stem cells; optimize transplant protocols
(This special issue belongs to the Section Cancer Pathophysiology)
Treatments of Uveal Melanoma
edited by
submission deadline 30 Jun 2025 | Viewed by 175 | Submission Open
Keywords: uveal melanoma; radiotherapy; radiation retinopathy; liver metastases; prognostication
(This special issue belongs to the Section Cancer Therapy)
Liquid Biopsy for Lung Cancer Treatment (2nd Edition)
edited by and Frullanti Elisa
submission deadline 30 Jun 2025 | Viewed by 154 | Submission Open
Keywords: cancer; lung cancer; new strategies; liquid biopsy; CTC; exosomes; Cf-NA; DdPCR; NGS
(This special issue belongs to the Section Cancer Biomarkers)
Peptide-Drug Conjugates for Cancer Therapy
edited by Hans-Georg Lerchen, and Anne-Sophie Rebstock
submission deadline 30 Jun 2025 | Viewed by 151 | Submission Open
Keywords: peptide– drug conjugates (PDCs); small molecule– drug conjugates (SMDCs); cyclic peptide; targeted drug delivery; tumor marker; radioconjugates; cytotoxic payload
(This special issue belongs to the Section Cancer Drug Development)
Clinical Epidemiology and Risk Prediction for Gastrointestinal Cancers submission deadline 1 Jul 2025 | 8 articles | Viewed by 14889 | Submission Open
Keywords: gastrointestinal cancers; genetic risk; polygenic risk scores; exposome; lifestyle risk factors; biomarkers; chemoprevention
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
PET/CT and Conventional Imaging in Cancers submission deadline 1 Jul 2025 | 6 articles | Viewed by 11672 | Submission Open
Keywords: PET/CT; CT; MR; conventional imaging; positron emission tomography; neoplasm; cancer
(This special issue belongs to the Section Methods and Technologies Development)
Beyond Cancer: Enhancing Quality of Life for Cancer Survivors
edited by , Maryam Lustberg and Muna Al-Khaifi
submission deadline 1 Jul 2025 | 8 articles | Viewed by 9898 | Submission Open
Keywords: psychosocial oncology; cancer survivorship; long-term effects of cancer; psychoeducational interventions; innovative care models; continuing education; knowledge translation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Therapeutic Strategies for Prostate Cancer
edited by Angelo Naselli and
submission deadline 1 Jul 2025 | 4 articles | Viewed by 7941 | Submission Open
Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies
(This special issue belongs to the Section Cancer Therapy)
New Insights into Prostate Cancer Radiotherapy
edited by
submission deadline 1 Jul 2025 | 5 articles | Viewed by 7077 | Submission Open
Keywords: prostate cancer; radiotherapy; radiation therapy
(This special issue belongs to the Section Cancer Therapy)
New Insights into Targeted Drugs for Breast Cancer (Volume II)
edited by and Jennifer Richer
submission deadline 1 Jul 2025 | 4 articles | Viewed by 5762 | Submission Open
Keywords: breast cancer targeted therapies treatment resistance HER2 hormone receptor-positive triple-negative breast cancer
(This special issue belongs to the Section Cancer Drug Development)
The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms
edited by
submission deadline 1 Jul 2025 | 3 articles | Viewed by 4963 | Submission Open
Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer
(This special issue belongs to the Section Cancer Therapy)
Advanced Research in Imaging-Guided Cancer Therapy
edited by Valentina Berti and
submission deadline 1 Jul 2025 | 2 articles | Viewed by 3132 | Submission Open
Keywords: imaging-guided therapies; theranostic; cancer; PET imaging; nuclear medicine; nuclear oncology; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments
edited by Christian Ott and Julius Höhne
submission deadline 1 Jul 2025 | 1 articles | Viewed by 2516 | Submission Open
Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy
(This special issue belongs to the Section Cancer Therapy)
Radiomics in Gynaecological Cancers submission deadline 1 Jul 2025 | 2 articles | Viewed by 2440 | Submission Open
Keywords: MRI; CT; PET; radiomics; gynecologic malignancies
(This special issue belongs to the Section Cancer Informatics and Big Data)
The Role of Imaging in Cervical Cancer
edited by , Emma R. Allanson and Ming Yin Lin
submission deadline 1 Jul 2025 | Viewed by 572 | Submission Open
Keywords: cervical cancer; staging; ultrasound; MRI; PET-CT; radiotherapy; image-guided brachytherapy
(This special issue belongs to the Section Methods and Technologies Development)
Surgical Innovations in Advanced Gastric Cancer
edited by Ugo Elmore, Francesco Puccetti and Andrea Cossu
submission deadline 1 Jul 2025 | Viewed by 97 | Submission Open
Keywords: gastric cancer; gastrectomy; oligometastatic cancer; recurrence; peritoneal carcinomatosis; multimodal management
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer: Tailored Rehabilitation Strategies to Address the Challenge of Survivorship Issues submission deadline 3 Jul 2025 | 5 articles | Viewed by 22624 | Submission Open
Keywords: breast cancer; rehabilitation; biomarkers; survivorship; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Advances in Neurofibromatosis
edited by Yunjia Chen and Yulong Fu
submission deadline 5 Jul 2025 | Viewed by 334 | Submission Open
Keywords: neurofibromatosis; schwannomatosis; NF1; NF2; SMARCB1; LZTR1
(This special issue belongs to the Section Molecular Cancer Biology)
Challenges and Opportunities for Novel Therapeutic Strategies in Pediatric Oncology
edited by and
submission deadline 6 Jul 2025 | 6 articles | Viewed by 9145 | Submission Open
Keywords: antibody-drug conjugate; bispecific antibody; cancer predisposition; CAR T cell; immunotherapy; leukemia; monoclonal antibody; neuroblastoma; pediatric cancer; photoimmunotherapy; precision medicine; sarcoma; translational research; tyrosine kinase inhibitor
(This special issue belongs to the Section Cancer Therapy)
Novel Strategies in the Prevention/Treatment of Colorectal Cancer submission deadline 10 Jul 2025 | 5 articles | Viewed by 21585 | Submission Open
Keywords: colorectal cancer; chemotherapy; chemoprevention; targeted therapy; kinase inhibitor; immunotherapy
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Genome Sequencing of Cancer: Identifying Targets and Biomarkers for Therapy
edited by
submission deadline 10 Jul 2025 | 4 articles | Viewed by 14624 | Submission Open
Keywords: cancer genome analysis; next-generation sequencing; heterogeneity; molecular targeted therapy; therapeutic biomarker; precision medicine
(This special issue belongs to the Section Cancer Biomarkers)
Combination Immunotherapy for Cancer Treatment submission deadline 10 Jul 2025 | 5 articles | Viewed by 11957 | Submission Open
Keywords: immunotherapy; immune checkpoint inhibitor; cancer vaccine; novel cancer therapy; treatment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Research on Clinical Treatment of Mesothelioma
edited by and Walid Hadid
submission deadline 10 Jul 2025 | 6 articles | Viewed by 7041 | Submission Open
Keywords: pleural mesothelioma; targeted therapy; local treatments; radiomics; genetic traits; occupational health; asbestos exposure
(This special issue belongs to the Section Clinical Research of Cancer)
The Future of Machine Learning in Predicting the Treatment Responses of Cancers
edited by Alfredo Vellido, and
submission deadline 11 Jul 2025 | 2 articles | Viewed by 4355 | Submission Open
Keywords: cancer treatment response; medical decision support systems; cancer outcome prediction; personalized medicine; pre-clinical models; artificial intelligence; machine learning; deep learning; progression-free survival; disease-free survival; event-free survival; overall survival; adverse event; quality of life; surrogate endpoint
(This special issue belongs to the Section Methods and Technologies Development)
Molecular Biology, Diagnosis and Management of Endometrial Cancer
edited by , and Thomas Vrekoussis
submission deadline 12 Jul 2025 | 2 articles | Viewed by 5541 | Submission Open
Keywords: endometrial cancer; molecular biology; lymph node dissection; sentinel lymph node mapping; sentinel lymph node dissection; surgery; systemic therapy; radiotherapy; fertility preservation; molecular targeted therapies
(This special issue belongs to the Section Molecular Cancer Biology)
Applications of Different Knowledge Graphs and Large Language Models in Diagnosis Cancers
edited by
submission deadline 12 Jul 2025 | Viewed by 732 | Submission Open
Keywords: deep learning; machine learning; large language models; cancer diagnosis; clinical decision support systems; image analysis; genomic data interpretation; biomedical literature mining; patient risk assessment; computational oncology; healthcare informatics; precision medicine; artificial intelligence; medical research; patient care
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
New Approaches in Radiotherapy for Cancer
edited by Dandan Zheng, Alexander Podgorsak and Olga Maria Dona Lemus
submission deadline 15 Jul 2025 | 16 articles | Viewed by 31338 | Submission Open
Keywords: adaptive radiotherapy; FLASH; artificial intelligence; SFRT; particle therapy; proton therapy; SRS; SBRT; HDR; 3D printing; immuno-radiotherapy; radiogenmics
(This special issue belongs to the Section Cancer Therapy)
Advances in Bacteria and Cancer
edited by
submission deadline 15 Jul 2025 | 4 articles | Viewed by 11176 | Submission Open
Keywords: pathogenic bacteria; microbiota; tumor-associated bacteria; probiotics; oncogenesis; metastasis; chemotherapy; cancerous cells; tumor microenvironment; cell signaling
(This special issue belongs to the Section Tumor Microenvironment)
Impact of Surgery on Brain Cancer and Other Central Nervous System Tumors
edited by Paolo Tini, and Giuseppe Minniti
submission deadline 15 Jul 2025 | 4 articles | Viewed by 7496 | Submission Open
Keywords: glioblastoma; low-grade gliomas; ependymomas; PNET; meningiomas; medulloblastomas; other brain tumors
(This special issue belongs to the Section Cancer Therapy)
Lung Cancer Proteogenomics: New Era, New Insights submission deadline 15 Jul 2025 | 2 articles | Viewed by 6981 | Submission Open
Keywords: lung cancer; genomic; transcriptomic; bioinformatic tools; multi-omics
(This special issue belongs to the Section Molecular Cancer Biology)
Gastric Cancer Metastases
edited by Yu-Yin Liu
submission deadline 15 Jul 2025 | 4 articles | Viewed by 6558 | Submission Open
Keywords: conversion surgery; stage IV gastric cancer; immunotherapy; unresectable gastric cancer; neo-adjuvant chemotherapy
(This special issue belongs to the Section Cancer Metastasis)
Recent Studies on Oral Cancer: Diagnostic Technologies, Pathology, and Surgery submission deadline 15 Jul 2025 | 1 articles | Viewed by 1540 | Submission Open
Keywords: oral cancer; oral squamous cell carcinoma; oral potentially malignant disorders; diagnostic technologies; oral surgery; maxillo-facial surgery; oncology; radiology; immunohistochemistry; molecular biology
(This special issue belongs to the Section Clinical Research of Cancer)
Endoscopic Diagnosis and Treatment in Hepato-Pancreato-Biliary (HPB) Cancers
edited by Mamoru Takenaka and
submission deadline 15 Jul 2025 | 1 articles | Viewed by 684 | Submission Open
Keywords: cancer; ERCP; EUS; interventional EUS; contrast-enhanced EUS; EUS-BD; EUS-FNA; EUS-FNB
(This special issue belongs to the Section Methods and Technologies Development)
Clinicopathological Study of Gynecologic Cancer (2nd Edition)
edited by
submission deadline 15 Jul 2025 | 1 articles | Viewed by 352 | Submission Open
Keywords: gynecological oncology; gynecological cancer; female cancer; uterine cancer; ovarian cancer; endometrial cancer; cancerogenesis; cancer biology; cell transformation; cancer pathology; cancer biology
(This special issue belongs to the Section Clinical Research of Cancer)
Medical Treatment for Urological Cancers submission deadline 15 Jul 2025 | Viewed by 328 | Submission Open
Keywords: prostate cancer; urothelial cancer; renal cancer; antibody– drug conjugates; cytotoxic chemotherapy; immune checkpoint inhibitors
(This special issue belongs to the Section Cancer Therapy)
Primary Central Nervous System Lymphoma: A Challenging Disease
edited by
submission deadline 15 Jul 2025 | Viewed by 276 | Submission Open
Keywords: primary central nervous system lymphoma (PCNSL); diffuse large B cell lymphoma (DLBCL); advanced imaging; novel therapies; prognostic markers
(This special issue belongs to the Section Clinical Research of Cancer)
Recent Updates on Treatment of Uveal Melanoma
edited by Richard D. Carvajal, Shaheer Khan and Brian Peter Marr
submission deadline 15 Jul 2025 | Viewed by 224 | Submission Open
Keywords: uveal melanoma; systemic therapies; surgical innovations; radiotherapy; genetic and molecular insights; translational research
(This special issue belongs to the Section Cancer Therapy)
Advanced Research on Radioresistant Tumors
edited by Mansoor M. Ahmed and Kamila Rawojć
submission deadline 15 Jul 2025 | Viewed by 204 | Submission Open
Keywords: radioresistant tumors; radiotherapy innovations; proton and heavy ion therapy; immunotherapy and radiotherapy combinations; genetic biomarkers; tumor hypoxia; combination treatment strategies; molecular oncology
(This special issue belongs to the Section Cancer Therapy)
The Elderly Multiple Myeloma Patient in the Era of Quad Therapy and CAR-T Cells
edited by James J. Ignatz-Hoover and Koen Van Besien
submission deadline 15 Jul 2025 | Viewed by 116 | Submission Open
Keywords: multiple myeloma; quad therapy; CAR-T; elderly
(This special issue belongs to the Section Cancer Therapy)
Application of Advanced Biomedical Imaging in Cancer Treatment submission deadline 20 Jul 2025 | 9 articles | Viewed by 35928 | Submission Open
Keywords: new horizons in cancer imaging; image-guided; therapy planning; oncology; therapy response assessment; recurrence assessment; experimental imaging; breast cancer; lung cancer; colorectal cancer; liver cancer; varia (lymphoma; CNS)
(This special issue belongs to the Section Methods and Technologies Development)
EVs and EPS in Cancer: Cell-to-Cell Communication, Diagnosis, and Evaluation of Cancer Therapy Response
edited by Irina Nazarenko and
submission deadline 20 Jul 2025 | 1 articles | Viewed by 2756 | Submission Open
Keywords: extracellular vesicles; EVs; particles; cancer; liquid biopsy; cell-cell communication
(This special issue belongs to the Section Tumor Microenvironment)
Hormones and Tumors
edited by Kiyoshi Takagi and
submission deadline 20 Jul 2025 | 1 articles | Viewed by 1300 | Submission Open
Keywords: diagnosis; hormone; prognosis; progression; therapy; tumor
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in the Molecular Pathogenesis of T-Cell Lymphoma
edited by
submission deadline 20 Jul 2025 | Viewed by 331 | Submission Open
Keywords: pathogenesis; molecular biology; T-cell neoplasia/lymphoma; biomarkers
(This special issue belongs to the Section Cancer Pathophysiology)
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