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  • Review
  • Open Access
94 Citations
20,901 Views
49 Pages

Deep learning has emerged as a powerful tool for medical image analysis and diagnosis, demonstrating high performance on tasks such as cancer detection. This literature review synthesizes current research on deep learning techniques applied to lung c...

  • Review
  • Open Access
85 Citations
15,931 Views
22 Pages

Digital twins (DTs) are becoming increasingly popular in various industries, and their potential for healthcare in the metaverse continues to attract attention. The metaverse is a virtual world where individuals interact with digital replicas of them...

  • Review
  • Open Access
83 Citations
21,290 Views
33 Pages

Genomics for Emerging Pathogen Identification and Monitoring: Prospects and Obstacles

  • Vishakha Vashisht,
  • Ashutosh Vashisht,
  • Ashis K. Mondal,
  • Jaspreet Farmaha,
  • Ahmet Alptekin,
  • Harmanpreet Singh,
  • Pankaj Ahluwalia,
  • Anaka Srinivas and
  • Ravindra Kolhe

Emerging infectious diseases (EIDs) pose an increasingly significant global burden, driven by urbanization, population explosion, global travel, changes in human behavior, and inadequate public health systems. The recent SARS-CoV-2 pandemic highlight...

  • Review
  • Open Access
71 Citations
25,231 Views
47 Pages

Recent Advances in Large Language Models for Healthcare

  • Khalid Nassiri and
  • Moulay A. Akhloufi

Recent advances in the field of large language models (LLMs) underline their high potential for applications in a variety of sectors. Their use in healthcare, in particular, holds out promising prospects for improving medical practices. As we highlig...

  • Review
  • Open Access
64 Citations
11,330 Views
16 Pages

This review explores the transformative integration of artificial intelligence (AI) and healthcare through conversational AI leveraging Natural Language Processing (NLP). Focusing on Large Language Models (LLMs), this paper navigates through various...

  • Article
  • Open Access
52 Citations
8,081 Views
21 Pages

Enhancing Brain Tumor Classification with Transfer Learning across Multiple Classes: An In-Depth Analysis

  • Syed Ahmmed,
  • Prajoy Podder,
  • M. Rubaiyat Hossain Mondal,
  • S M Atikur Rahman,
  • Somasundar Kannan,
  • Md Junayed Hasan,
  • Ali Rohan and
  • Alexander E. Prosvirin

This study focuses on leveraging data-driven techniques to diagnose brain tumors through magnetic resonance imaging (MRI) images. Utilizing the rule of deep learning (DL), we introduce and fine-tune two robust frameworks, ResNet 50 and Inception V3,...

  • Review
  • Open Access
43 Citations
10,749 Views
14 Pages

Recent advancements in artificial intelligence (AI) have facilitated its widespread adoption in primary medical services, addressing the demand–supply imbalance in healthcare. Vision Transformers (ViT) have emerged as state-of-the-art computer...

  • Article
  • Open Access
42 Citations
6,488 Views
26 Pages

Advancing Early Leukemia Diagnostics: A Comprehensive Study Incorporating Image Processing and Transfer Learning

  • Rezaul Haque,
  • Abdullah Al Sakib,
  • Md Forhad Hossain,
  • Fahadul Islam,
  • Ferdaus Ibne Aziz,
  • Md Redwan Ahmed,
  • Somasundar Kannan,
  • Ali Rohan and
  • Md Junayed Hasan

Disease recognition has been revolutionized by autonomous systems in the rapidly developing field of medical technology. A crucial aspect of diagnosis involves the visual assessment and enumeration of white blood cells in microscopic peripheral blood...

  • Article
  • Open Access
39 Citations
9,984 Views
26 Pages

Supporting the Demand on Mental Health Services with AI-Based Conversational Large Language Models (LLMs)

  • Tin Lai,
  • Yukun Shi,
  • Zicong Du,
  • Jiajie Wu,
  • Ken Fu,
  • Yichao Dou and
  • Ziqi Wang

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which heightened the need for timely and professional mental health support. Online psychological counselling emerged...

  • Communication
  • Open Access
37 Citations
10,031 Views
21 Pages

The Crucial Role of Interdisciplinary Conferences in Advancing Explainable AI in Healthcare

  • Ankush U. Patel,
  • Qiangqiang Gu,
  • Ronda Esper,
  • Danielle Maeser and
  • Nicole Maeser

As artificial intelligence (AI) integrates within the intersecting domains of healthcare and computational biology, developing interpretable models tailored to medical contexts is met with significant challenges. Explainable AI (XAI) is vital for fos...

  • Review
  • Open Access
36 Citations
8,442 Views
16 Pages

This article delves into the intersection of generative AI and digital twins within drug discovery, exploring their synergistic potential to revolutionize pharmaceutical research and development. Through various instances and examples, we illuminate...

  • Article
  • Open Access
36 Citations
4,782 Views
15 Pages

Myocardial Infarction (MI) is the death of the heart muscle caused by lack of oxygenated blood flow to the heart muscle. It has been the main cause of death worldwide. The fastest way to detect MI is by using an electrocardiogram (ECG) device, which...

  • Article
  • Open Access
35 Citations
8,138 Views
14 Pages

A common consequence of diabetes mellitus called diabetic retinopathy (DR) results in lesions on the retina that impair vision. It can cause blindness if not detected in time. Unfortunately, DR cannot be reversed, and treatment simply keeps eyesight...

  • Article
  • Open Access
32 Citations
3,924 Views
13 Pages

Identifying Potent Fat Mass and Obesity-Associated Protein Inhibitors Using Deep Learning-Based Hybrid Procedures

  • Kannan Mayuri,
  • Durairaj Varalakshmi,
  • Mayakrishnan Tharaheswari,
  • Chaitanya Sree Somala,
  • Selvaraj Sathya Priya,
  • Nagaraj Bharathkumar,
  • Renganathan Senthil,
  • Raja Babu Singh Kushwah,
  • Sundaram Vickram and
  • Konda Mani Saravanan
  • + 1 author

The fat mass and obesity-associated (FTO) protein catalyzes metal-dependent modifications of nucleic acids, namely the demethylation of methyl adenosine inside mRNA molecules. The FTO protein has been identified as a potential target for developing a...

  • Article
  • Open Access
29 Citations
11,904 Views
12 Pages

Background: Currently, discriminating Iron Deficiency Anemia (IDA) from other anemia requires an expensive test (serum ferritin). Complete Blood Count (CBC) tests are less costly and more widely available. Machine learning models have not yet been ap...

  • Article
  • Open Access
27 Citations
8,472 Views
15 Pages

Real-Time Jaundice Detection in Neonates Based on Machine Learning Models

  • Ahmad Yaseen Abdulrazzak,
  • Saleem Latif Mohammed,
  • Ali Al-Naji and
  • Javaan Chahl

Introduction: Despite the many attempts made by researchers to diagnose jaundice non-invasively using machine learning techniques, the low amount of data used to build their models remains the key factor limiting the performance of their models. Obje...

  • Review
  • Open Access
26 Citations
9,694 Views
26 Pages

Artificial Intelligence (AI) and deep learning models have revolutionized diagnosis, prognostication, and treatment planning by extracting complex patterns from medical images, enabling more accurate, personalized, and timely clinical decisions. Desp...

  • Review
  • Open Access
26 Citations
29,516 Views
40 Pages

Generative Artificial Intelligence in Healthcare: Applications, Implementation Challenges, and Future Directions

  • Syed Arman Rabbani,
  • Mohamed El-Tanani,
  • Shrestha Sharma,
  • Syed Salman Rabbani,
  • Yahia El-Tanani,
  • Rakesh Kumar and
  • Manita Saini

Generative artificial intelligence (AI) is rapidly transforming healthcare systems since the advent of OpenAI in 2022. It encompasses a class of machine learning techniques designed to create new content and is classified into large language models (...

  • Review
  • Open Access
25 Citations
16,050 Views
64 Pages

Lung cancer is a leading cause of cancer-related deaths worldwide, emphasizing the significance of early detection. Computer-aided diagnostic systems have emerged as valuable tools for aiding radiologists in the analysis of medical images, particular...

  • Article
  • Open Access
24 Citations
5,536 Views
18 Pages

Towards Effective Emotion Detection: A Comprehensive Machine Learning Approach on EEG Signals

  • Ietezaz Ul Hassan,
  • Raja Hashim Ali,
  • Zain ul Abideen,
  • Ali Zeeshan Ijaz and
  • Talha Ali Khan

Emotion detection assumes a pivotal role in the evaluation of adverse psychological attributes, such as stress, anxiety, and depression. This study undertakes an exploration into the prospective capacities of machine learning to prognosticate individ...

  • Article
  • Open Access
21 Citations
10,417 Views
16 Pages

Breast cancer is among the most common cancers found in women, causing cancer-related deaths and making it a severe public health issue. Early prediction of breast cancer can increase the chances of survival and promote early medical treatment. Moreo...

  • Article
  • Open Access
21 Citations
8,961 Views
25 Pages

Survey of Multimodal Medical Question Answering

  • Hilmi Demirhan and
  • Wlodek Zadrozny

Multimodal medical question answering (MMQA) is a vital area bridging healthcare and Artificial Intelligence (AI). This survey methodically examines the MMQA research published in recent years. We collect academic literature through Google Scholar, a...

  • Review
  • Open Access
20 Citations
14,725 Views
17 Pages

Artificial Intelligence in Wound Care: A Narrative Review of the Currently Available Mobile Apps for Automatic Ulcer Segmentation

  • Davide Griffa,
  • Alessio Natale,
  • Yuri Merli,
  • Michela Starace,
  • Nico Curti,
  • Martina Mussi,
  • Gastone Castellani,
  • Davide Melandri,
  • Bianca Maria Piraccini and
  • Corrado Zengarini

Introduction: Chronic ulcers significantly burden healthcare systems, requiring precise measurement and assessment for effective treatment. Traditional methods, such as manual segmentation, are time-consuming and error-prone. This review evaluates th...

  • Article
  • Open Access
19 Citations
4,449 Views
12 Pages

Transfer-Learning Approach for Enhanced Brain Tumor Classification in MRI Imaging

  • Amarnath Amarnath,
  • Ali Al Bataineh and
  • Jeremy A. Hansen

Background: Intracranial neoplasm, often referred to as a brain tumor, is an abnormal growth or mass of tissues in the brain. The complexity of the brain and the associated diagnostic delays cause significant stress for patients. This study aims to e...

  • Article
  • Open Access
19 Citations
6,756 Views
36 Pages

Early Breast Cancer Detection Based on Deep Learning: An Ensemble Approach Applied to Mammograms

  • Youness Khourdifi,
  • Alae El Alami,
  • Mounia Zaydi,
  • Yassine Maleh and
  • Omar Er-Remyly

Background: Breast cancer is one of the leading causes of death in women, making early detection through mammography crucial for improving survival rates. However, human interpretation of mammograms is often prone to diagnostic errors. This study add...

  • Review
  • Open Access
19 Citations
7,873 Views
12 Pages

Exploring the Role of ChatGPT in Oncology: Providing Information and Support for Cancer Patients

  • Maurizio Cè,
  • Vittoria Chiarpenello,
  • Alessandra Bubba,
  • Paolo Florent Felisaz,
  • Giancarlo Oliva,
  • Giovanni Irmici and
  • Michaela Cellina

Introduction: Oncological patients face numerous challenges throughout their cancer journey while navigating complex medical information. The advent of AI-based conversational models like ChatGPT (San Francisco, OpenAI) represents an innovation in on...

  • Article
  • Open Access
18 Citations
5,139 Views
23 Pages

Early detection of dyslexia and learning disorders is vital for avoiding a learning disability, as well as supporting dyslexic students by tailoring academic programs to their needs. Several studies have investigated using supervised algorithms to sc...

  • Article
  • Open Access
18 Citations
4,777 Views
23 Pages

Naturalize Revolution: Unprecedented AI-Driven Precision in Skin Cancer Classification Using Deep Learning

  • Mohamad Abou Ali,
  • Fadi Dornaika,
  • Ignacio Arganda-Carreras,
  • Hussein Ali and
  • Malak Karaouni

Background: In response to the escalating global concerns surrounding skin cancer, this study aims to address the imperative for precise and efficient diagnostic methodologies. Focusing on the intricate task of eight-class skin cancer classification,...

  • Review
  • Open Access
18 Citations
6,823 Views
19 Pages

An Overview of Approaches and Methods for the Cognitive Workload Estimation in Human–Machine Interaction Scenarios through Wearables Sensors

  • Sabrina Iarlori,
  • David Perpetuini,
  • Michele Tritto,
  • Daniela Cardone,
  • Alessandro Tiberio,
  • Manish Chinthakindi,
  • Chiara Filippini,
  • Luca Cavanini,
  • Alessandro Freddi and
  • Andrea Monteriù
  • + 2 authors

Background: Human-Machine Interaction (HMI) has been an important field of research in recent years, since machines will continue to be embedded in many human actvities in several contexts, such as industry and healthcare. Monitoring in an ecological...

  • Review
  • Open Access
17 Citations
8,671 Views
17 Pages

This review explores the integration of artificial intelligence (AI) and machine learning (ML) into kidney transplantation (KT), set against the backdrop of a significant donor organ shortage and the evolution of ‘Next-Generation Healthcare&rsq...

  • Article
  • Open Access
17 Citations
7,877 Views
13 Pages

Lip-Reading Advancements: A 3D Convolutional Neural Network/Long Short-Term Memory Fusion for Precise Word Recognition

  • Themis Exarchos,
  • Georgios N. Dimitrakopoulos,
  • Aristidis G. Vrahatis,
  • Georgios Chrysovitsiotis,
  • Zoi Zachou and
  • Efthymios Kyrodimos

Lip reading, the art of deciphering spoken words from the visual cues of lip movements, has garnered significant interest for its potential applications in diverse fields, including assistive technologies, human–computer interaction, and securi...

  • Article
  • Open Access
17 Citations
6,942 Views
17 Pages

Assessment of Voice Disorders Using Machine Learning and Vocal Analysis of Voice Samples Recorded through Smartphones

  • Michele Giuseppe Di Cesare,
  • David Perpetuini,
  • Daniela Cardone and
  • Arcangelo Merla

Background: The integration of edge computing into smart healthcare systems requires the development of computationally efficient models and methodologies for monitoring and detecting patients’ healthcare statuses. In this context, mobile devic...

  • Review
  • Open Access
16 Citations
9,571 Views
26 Pages

Background: Over the past few years, clinical studies have utilized machine learning in telehealth and smart care for disease management, self-management, and managing health issues like pulmonary diseases, heart failure, diabetes screening, and intr...

  • Systematic Review
  • Open Access
16 Citations
26,133 Views
14 Pages

Networks in Healthcare: A Systematic Review

  • Santhosh Kumar Rajamani and
  • Radha Srinivasan Iyer

Networks form the backbone of any healthcare system. Various databases were searched with relevant keywords, data were abstracted, and numerous papers were appraised for this synthesis. This compiled systematic review gives a comprehensive overview o...

  • Review
  • Open Access
15 Citations
4,900 Views
19 Pages

In pharmaceutical research and development, pursuing novel therapeutics and optimizing existing drugs have been revolutionized by the fusion of cutting-edge technologies and computational methodologies. Over the past few decades, the field of drug de...

  • Article
  • Open Access
15 Citations
5,835 Views
28 Pages

Background: Transforming one-dimensional (1D) biomedical signals into two-dimensional (2D) images enables the application of convolutional neural networks (CNNs) for classification tasks. In this study, we investigated the effectiveness of different...

  • Article
  • Open Access
14 Citations
2,079 Views
20 Pages

Background: Malignant breast cancer is the most common cancer affecting women worldwide. The COVID-19 pandemic appears to have slowed the diagnostic process, leading to an enhanced use of invasive approaches such as mastectomy. The increased use of a...

  • Article
  • Open Access
14 Citations
4,740 Views
24 Pages

Background: Creating models to differentiate self-reported mental workload perceptions is challenging and requires machine learning to identify features from EEG signals. EEG band ratios quantify human activity, but limited research on mental workloa...

  • Editorial
  • Open Access
14 Citations
6,985 Views
9 Pages

Biomedical informatics can be considered as a multidisciplinary research and educational field situated at the intersection of computational sciences (including computer science, data science, mathematics, and statistics), biology, and medicine. In r...

  • Review
  • Open Access
14 Citations
3,127 Views
23 Pages

Deep Learning and Federated Learning for Screening COVID-19: A Review

  • M. Rubaiyat Hossain Mondal,
  • Subrato Bharati,
  • Prajoy Podder and
  • Joarder Kamruzzaman

Since December 2019, a novel coronavirus disease (COVID-19) has infected millions of individuals. This paper conducts a thorough study of the use of deep learning (DL) and federated learning (FL) approaches to COVID-19 screening. To begin, an evaluat...

  • Review
  • Open Access
14 Citations
5,957 Views
28 Pages

Automated Methods for Tuberculosis Detection/Diagnosis: A Literature Review

  • Marios Zachariou,
  • Ognjen Arandjelović and
  • Derek James Sloan

Tuberculosis (TB) is one of the leading infectious causes of death worldwide. The effective management and public health control of this disease depends on early detection and careful treatment monitoring. For many years, the microscopy-based analysi...

  • Perspective
  • Open Access
14 Citations
8,685 Views
13 Pages

AlphaFold2 Update and Perspectives

  • Sébastien Tourlet,
  • Ragousandirane Radjasandirane,
  • Julien Diharce and
  • Alexandre G. de Brevern

Access to the three-dimensional (3D) structural information of macromolecules is of major interest in both fundamental and applied research. Obtaining this experimental data can be complex, time consuming, and costly. Therefore, in silico computation...

  • Review
  • Open Access
13 Citations
5,142 Views
16 Pages

Should AI-Powered Whole-Genome Sequencing Be Used Routinely for Personalized Decision Support in Surgical Oncology—A Scoping Review

  • Kokiladevi Alagarswamy,
  • Wenjie Shi,
  • Aishwarya Boini,
  • Nouredin Messaoudi,
  • Vincent Grasso,
  • Thomas Cattabiani,
  • Bruce Turner,
  • Roland Croner,
  • Ulf D. Kahlert and
  • Andrew Gumbs

In this scoping review, we delve into the transformative potential of artificial intelligence (AI) in addressing challenges inherent in whole-genome sequencing (WGS) analysis, with a specific focus on its implications in oncology. Unveiling the limit...

  • Article
  • Open Access
13 Citations
8,569 Views
26 Pages

Synthetic MRI Generation from CT Scans for Stroke Patients

  • Jake McNaughton,
  • Samantha Holdsworth,
  • Benjamin Chong,
  • Justin Fernandez,
  • Vickie Shim and
  • Alan Wang

CT scans are currently the most common imaging modality used for suspected stroke patients due to their short acquisition time and wide availability. However, MRI offers superior tissue contrast and image quality. In this study, eight deep learning m...

  • Review
  • Open Access
13 Citations
13,408 Views
70 Pages

Advancements in Breast Cancer Detection: A Review of Global Trends, Risk Factors, Imaging Modalities, Machine Learning, and Deep Learning Approaches

  • Md. Atiqur Rahman,
  • M. Saddam Hossain Khan,
  • Yutaka Watanobe,
  • Jarin Tasnim Prioty,
  • Tasfia Tahsin Annita,
  • Samura Rahman,
  • Md. Shakil Hossain,
  • Saddit Ahmed Aitijjo,
  • Rafsun Islam Taskin and
  • Touhid Bhuiyan
  • + 2 authors

Breast cancer remains a critical global health challenge, with over 2.1 million new cases annually. This review systematically evaluates recent advancements (2022–2024) in machine and deep learning approaches for breast cancer detection and ris...

  • Article
  • Open Access
12 Citations
3,597 Views
10 Pages

Hearables: In-Ear Multimodal Data Fusion for Robust Heart Rate Estimation

  • Marek Żyliński,
  • Amir Nassibi,
  • Edoardo Occhipinti,
  • Adil Malik,
  • Matteo Bermond,
  • Harry J. Davies and
  • Danilo P. Mandic

Background: Ambulatory heart rate (HR) monitors that acquire electrocardiogram (ECG) or/and photoplethysmographm (PPG) signals from the torso, wrists, or ears are notably less accurate in tasks associated with high levels of movement compared to clin...

  • Article
  • Open Access
11 Citations
4,803 Views
17 Pages

Utilizing Immunoinformatics for mRNA Vaccine Design against Influenza D Virus

  • Elijah Kolawole Oladipo,
  • Stephen Feranmi Adeyemo,
  • Modinat Wuraola Akinboade,
  • Temitope Michael Akinleye,
  • Kehinde Favour Siyanbola,
  • Precious Ayomide Adeogun,
  • Victor Michael Ogunfidodo,
  • Christiana Adewumi Adekunle,
  • Olubunmi Ayobami Elutade and
  • Helen Onyeaka
  • + 4 authors

Background: Influenza D Virus (IDV) presents a possible threat to animal and human health, necessitating the development of effective vaccines. Although no human illness linked to IDV has been reported, the possibility of human susceptibility to infe...

  • Article
  • Open Access
11 Citations
7,167 Views
12 Pages

Background: Heart failure poses a significant global health challenge, with high rates of readmission and mortality. Accurate models to predict these outcomes are essential for effective patient management. This study investigates the impact of data...

  • Article
  • Open Access
11 Citations
8,462 Views
21 Pages

Background: Epilepsy is one of the most common and devastating neurological disorders, manifesting with seizures and affecting approximately 1–2% of the world’s population. The criticality of seizure occurrence and associated risks, combi...

  • Article
  • Open Access
10 Citations
3,502 Views
18 Pages

Harnessing Immunoinformatics for Precision Vaccines: Designing Epitope-Based Subunit Vaccines against Hepatitis E Virus

  • Elijah Kolawole Oladipo,
  • Emmanuel Oluwatobi Dairo,
  • Comfort Olukemi Bamigboye,
  • Ayodeji Folorunsho Ajayi,
  • Olugbenga Samson Onile,
  • Olumuyiwa Elijah Ariyo,
  • Esther Moradeyo Jimah,
  • Olubukola Monisola Oyawoye,
  • Julius Kola Oloke and
  • Helen Onyeaka
  • + 2 authors

Background/Objectives: Hepatitis E virus (HEV) is an RNA virus recognized to be spread mainly by fecal-contaminated water. Its infection is known to be a serious threat to public health globally, mostly in developing countries, in which Africa is one...

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BioMedInformatics - ISSN 2673-7426