2026 June - 15 articles
Immunohistochemistry (IHC) is a widely used method for detecting specific proteins in tissue samples, helping diagnose diseases such as cancer. Traditional analysis methods rely heavily on human interpretation, which can lead to inconsistencies. In t...
Lung cancer is the deadliest cause of cancer-related deaths worldwide, and early and accurate detection is key to improving patient outcomes. IQ-OTH/NCCD CT scan images are used in this study to present an optimized computer-aided diagnosis (CAD) fra...
Heterogeneity is central to the credibility, transportability, and clinical interpretation of meta-analytic evidence, yet its assessment is frequently reduced to isolated or misinterpreted statistics. This tutorial provides a clinically oriented fram...
The increasing prevalence of autoimmune thyroid diseases and thyroid cancer highlights the urgent need for improved diagnostic support approaches. Traditional diagnostic methods often rely primarily on biochemical markers or qualitative imaging evalu...
Electrocardiogram (ECG) arrhythmia classification remains critical for automated cardiac diagnosis, yet feature extraction methods are frequently adopted without systematic comparative evaluation. This study presents a controlled comparative analysis...
This study developed two Causal Graphical Models (CGMs) to analyze the transitions associated with Bacterial Vaginosis (BV) and to identify key bacterial species at each stage. BV results from an imbalance in the vaginal microbiota, whose composition...
Gliomas represent the most prevalent type of brain tumor, with their most aggressive variant, glioblastoma multiforme, associated with high mortality rates. Due to their elevated molecular heterogeneity, accurate classification of gliomas has present...
Antiretroviral drugs (ARVDs) remain the cornerstone of HIV/AIDS management, but their therapeutic efficacy and safety are highly influenced by bioconversion processes such as hepatic metabolism and enzymatic transformation. Variability in metabolic p...
Background: Targeting Apolipoprotein E4 (ApoE4) represents a frontier in Alzheimer’s disease therapeutics. This study investigates the therapeutic potential of a nutraceutical panel (Polydatin, trans-resveratrol, luteolin, and PEA) by exploring...
Background: This study examines the clinical efficacy of daratumumab when combined with other therapeutic agents in patients with multiple myeloma, with a focus on key outcomes including overall response, progression-free survival (PFS), and stringen...
Glaucoma is a chronic progressive optic neuropathy causing irreversible blindness globally, underscoring the need for reliable diagnostic tools. While visual field (VF) testing remains the clinical standard, it has significant limitations, including...
Myocardial edema is associated with cardiac electrical instability, but the cellular mechanisms linking osmotic cell swelling to arrhythmias remain unclear. Hypoosmotic conditions are hypothesized to drive transitions between dynamical regimes (e.g.,...
Background: Accurate and early detection of hematological disorders from microscopic peripheral blood smear images remains a technically challenging task due to inherent imaging limitations, including noise contamination, low contrast, staining varia...
Background: Hemagglutinin (HA) is the primary surface protein of the influenza A virus, determining its subtype and antigenic properties. Traditional subtype classification methods rely on DNA or amino acid sequence analysis, which does not account f...
Background: Liver fibrosis arises from chronic liver injury and remains a major clinical challenge due to its progression toward cirrhosis and hepatocellular carcinoma, as well as the absence of approved antifibrotic therapies. This study aimed to ch...
