- Article
Development and Validation of a CatBoost-Based Model for Predicting Significant Creatinine Elevation in ICU Patients Receiving Vancomycin Therapy
- Junyi Fan,
- Li Sun,
- Shuheng Chen,
- Yong Si,
- Minoo Ahmadi and
- Maryam Pishgar
Vancomycin remains a cornerstone for severe Gram-positive infections in the ICU, yet creatinine elevation—a sensitive marker of early renal stress—occurs frequently and complicates therapy. We developed a machine learning model to predict...

