World Hepatitis Day—“Hepatitis: Let’s Break It Down”, 28 July 2025
World Hepatitis Day is observed each year on 28 July to raise awareness of viral hepatitis, a type of inflammation of the liver that causes severe liver disease and liver cancer.
The theme for 2025—“Hepatitis: Let’s Break It Down”—calls for urgent action to dismantle the financial, social and systemic barriers, including stigma, that stand in the way of hepatitis elimination and liver cancer prevention.
Chronic hepatitis B and C silently cause liver damage and cancer—despite them being preventable, treatable, and, in the case of hepatitis C, curable. The theme emphasizes the need to simplify, scale up, and integrate hepatitis services—vaccination, safe injection practices, harm reduction and especially testing and treatment—into national health systems.
The campaign is a reminder that we must act now to expand access, integrate care, and end hepatitis as a public health problem by 2030.
In recognition of this important day, we recommend the following related articles, Special Issues, and journals spanning multidisciplinary fields, including clinical medicine. We believe that promoting such research contributes to enhanced public awareness and a greater understanding of viral hepatitis, an inflammation of the liver that causes severe liver disease and liver cancer.
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Biology & Life Sciences |
Medicine & Pharmacology |
“Curcumin Nanocarriers in the Protection Against Iron- and Alcohol-Induced Oxidative Stress in a Cellular Model of Liver Disease”
by Lucy Petagine, Mohammed G. Zariwala, Satyanarayana Somavarapu, Stefanie Ho Yi Chan and Vinood B. Patel
Biology 2025, 14(5), 455; https://doi.org/10.3390/biology14050455
“Hepatic Estrogen Receptor Alpha Overexpression Protects Against Hepatic Insulin Resistance and MASLD”
by Ester S. Alves, Jessica D. M. Santos, Alessandra G. Cruz, Felipe N. Camargo, Carlos H. Z. Talarico, Anne R. M. Santos, Carlos A. A. Silva, Henrique J. N. Morgan, Sandro L. Matos, Layanne C. C. Araujo et al.
Pathophysiology 2025, 32(1), 1; https://doi.org/10.3390/pathophysiology32010001
“Change in Estimated Glomerular Filtration Rate After Direct-Acting Antiviral Treatment in Chronic Hepatitis C Patients”
by Gantogtokh Dashjamts, Amin-Erdene Ganzorig, Yumchinsuren Tsedendorj, Dolgion Daramjav, Enkhmend Khayankhyarvaa, Bolor Ulziitsogt, Otgongerel Nergui, Ganchimeg Dondov, Tegshjargal Badamjav, Tulgaa Lonjid et al.
Diseases 2025, 13(2), 26; https://doi.org/10.3390/diseases13020026
“Effects of SARS-CoV-2 Spike S1 Subunit on the Interplay Between Hepatitis B and Hepatocellular Carcinoma Related Molecular Processes in Human Liver”
by Giovanni Colonna
Livers 2025, 5(1), 1; https://doi.org/10.3390/livers5010001
“Liver Cancer Neuroscience: Regulating Liver Tumors via Selective Hepatic Vagotomy”
by Kylynda C. Bauer, Shadin Ghabra, Chi Ma Lee Chedester and Tim F. Greten
Methods Protoc. 2024, 7(6), 99; https://doi.org/10.3390/mps7060099
“Role of Circulating microRNAs in Liver Disease and HCC: Focus on miR-122”
by Francesco Colaianni, Veronica Zelli, Chiara Compagnoni, Martina Sara Miscione, Mario Rossi, Davide Vecchiotti, Monica Di Padova, Edoardo Alesse, Francesca Zazzeroni and Alessandra Tessitore
Genes 2024, 15(10), 1313; https://doi.org/10.3390/genes15101313
“Impact of Hepatitis Delta Virus Infection on the Selection of Hepatitis B Surface Antigen Mutations”
by Kabo Baruti,Wonderful T. Choga, Bonolo B. Phinius, Basetsana Phakedi, Lynnette Bhebhe, Gorata G. A. Mpebe, Patience C. Motshosi, Tsholofelo Ratsoma, Sikhulile Moyo, Mosimanegape Jongman et al.
Genes 2024, 15(8), 982; https://doi.org/10.3390/genes15080982
“NAFLD/MASLD and the Gut–Liver Axis: From Pathogenesis to Treatment Options”
by Natalia G. Vallianou, Dimitris Kounatidis, Sotiria Psallida, Nikolaos Vythoulkas-Biotis, Andreas Adamou, Tatiana Zachariadou, Sofia Kargioti, Irene Karampela and Maria Dalamaga
Metabolites 2024, 14(7), 366; https://doi.org/10.3390/metabo14070366
“miRNA Expression and HCC Occurrence in HCV Cirrhotic Patients Treated with Direct Acting Antivirals”
by Antonietta Romano, Alessandra Brocca, Zoe Mariño, Sofía Pérez-del-Pulgar, Sabela Lens, Loreto Boix, María Reig, Jordi Bruix, Giulio Ceolotto, Valeria Calvino et al.
Livers 2024, 4(2), 275-286; https://doi.org/10.3390/livers4020020
“The Full-Genome Analysis and Generation of an Infectious cDNA Clone of a Genotype 6 Hepatitis E Virus Variant Obtained from a Japanese Wild Boar: In Vitro Cultivation in Human Cell Lines”
by Putu Prathiwi Primadharsini, Masaharu Takahashi, Tsutomu Nishizawa, Yukihiro Sato, Shigeo Nagashima, Kazumoto Murata and Hiroaki Okamoto
Viruses 2024, 16(6), 842; https://doi.org/10.3390/v16060842
“Hepatitis C Prevalence and Birth Outcomes among Pregnant Women in the United States: A 2010–2020 Population Study”
by Paul Wasuwanich, Songyos Rajborirug, Robert S. Egerman, Tony S. Wen and Wikrom Karnsakul
Pathogens 2024, 13(4), 321; https://doi.org/10.3390/pathogens13040321
“Prospects for Controlling Hepatitis B Globally”
by Vicente Soriano, Víctor Moreno-Torres, Ana Treviño, Fernando de Jesús, Octavio Corral and Carmen de Mendoza
Pathogens 2024, 13(4), 291; https://doi.org/10.3390/pathogens13040291
“Longterm Outcome of Therapeutic Vaccination with a Third Generation Pre-S/S HBV Vaccine (PreHevbrioR) of Chronically HBV Infected Patients”
by Hedwig Roggendorf, Daniel Shouval, Michael Roggendorf and Guido Gerken
J. Pers. Med. 2024, 14(4), 364; https://doi.org/10.3390/jpm14040364
“NAFLD Fibrosis Progression and Type 2 Diabetes: The Hepatic–Metabolic Interplay”
by Simona Cernea
Life 2024, 14(2), 272; https://doi.org/10.3390/life14020272
“Updated Clinical Guidelines on the Management of Hepatitis C Infection in Children”
by Chaowapong Jarasvaraparn, Christopher Hartley and Wikrom Karnsakul
Pathogens 2024, 13(2), 180; https://doi.org/10.3390/pathogens13020180
“Non-Invasive Assessment of Liver Fibrosis in Hepatitis B Patients”
by Chinmay Bera, Nashla Hamdan-Perez and Keyur Patel
J. Clin. Med. 2024, 13(4), 1046; https://doi.org/10.3390/jcm13041046
“Real-World Utilization of Corticosteroids in Severe Alcoholic Hepatitis: Eligibility, Response, and Outcomes”
by Ana-Maria Singeap, Horia Minea, Oana Petrea, Madalina-Andreea Robea, Ioana-Miruna Balmuș, Raluca Duta, Ovidiu-Dumitru Ilie, Carmen Diana Cimpoesu, Carol Stanciu and Anca Trifan
Medicina 2024, 60(2), 311; https://doi.org/10.3390/medicina60020311
“Autoimmune Hepatitis: A Diagnostic and Therapeutic Overview”
by Lydia A. Mercado, Fernando Gil-Lopez, Razvan M. Chirila and Denise M. Harnois
Diagnostics 2024, 14(4), 382; https://doi.org/10.3390/diagnostics14040382
“Hepatoprotective Effects of Flavonoids against Benzo[a]Pyrene-Induced Oxidative Liver Damage along Its Metabolic Pathways”
by Min Kim, Seung-Cheol Jee and Jung-Suk Sung
Antioxidants 2024, 13(2), 180; https://doi.org/10.3390/antiox13020180
”Enhancing Liver Delivery of Gold Nanoclusters via Human Serum Albumin Encapsulation for Autoimmune Hepatitis Alleviation”
by Cong Meng, Yu Liu, Yuping Ming, Cao Lu, Yanggege Li, Yulu Zhang, Dongdong Su, Xueyun Gao and Qing Yuan
Pharmaceutics 2024, 16(1), 110; https://doi.org/10.3390/pharmaceutics16010110
“Hepatitis B Virus Reactivation with Immunosuppression: A Hidden Threat?”
by Sama Anvari and Keith Tsoi
J. Clin. Med. 2024, 13(2), 393; https://doi.org/10.3390/jcm13020393
“Metabolic Dysfunction-Associated Fatty Liver Disease and Chronic Viral Hepatitis: The Interlink”
by Cornelius J. Fernandez, Mohammed Alkhalifah, Hafsa Afsar and Joseph M. Pappachan
Pathogens 2024, 13(1), 68; https://doi.org/10.3390/pathogens13010068
“A Case Report: Idiopathic or Drug-Induced Autoimmune Hepatitis—Can We Draw a Line?”
by Dorotea Božić, Ante Tonkić, Jr,Katarina Vukojevic and Maja Radman
Clin. Pract. 2023, 13(6), 1393–1399; https://doi.org/10.3390/clinpract13060125
“Liver dECM–Gelatin Composite Bioink for Precise 3D Printing of Highly Functional Liver Tissues”
by Min Kyeong Kim, Wonwoo Jeong and Hyun-Wook Kang
J. Funct. Biomater. 2023, 14(8), 417; https://doi.org/10.3390/jfb14080417
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“Viral Hepatitis: Diagnosis, Treatment and Management” |
“New Insights into Diagnosis and Therapeutic Strategies for Chronic Liver Diseases” |
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“The Surveillance, Prevention, and Treatment of Viral Hepatitis: Looking Forward to Global Elimination” |
“Viral Hepatitis and Therapeutic Strategies” |
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“Genetic Analysis of Hepatitis Virus Infection” |
“Oxidative Stress in Hepatic Diseases” |
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“Viral Hepatitis Among Specific Populations: Epidemiology, Transmission, Treatment, and Prevention” |
“Biology of Liver Diseases” |
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“Hepatitis E Virus (HEV) Infection Among Humans and Animals: Epidemiology, Clinical Characteristics, Treatment and Prevention—2nd Edition” |
“Human Hepatitis Viruses and Their Animal Homologues” |
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“Advances in Hepatitis: Prevention, Treatment, and Global Health Impact” |
“Pathogenesis of Viral Hepatitis” |
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“Liver Diseases: Diagnosis and Treatment in the Era of Personalized Medicine” |
“Gastrointestinal and Liver Diseases: New Advances in Diagnosis and Prognosis” |
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